Debiopharm SA

Lausanne, Switzerland

Debiopharm SA

Lausanne, Switzerland
SEARCH FILTERS
Time filter
Source Type

News Article | May 9, 2017
Site: tech.eu

Swiss BC Platforms, which provides genomic data management solutions, has raised $10 million in Series B financing. The round was led by Debiopharm Innovation Fund in conjunction with Tesi, a Finnish venture capital and private equity company, with participation from BC Platforms’ existing investors. BC Platforms' genomic data management platform enables data integration and secure analysis of molecular and clinical information. The company currently works with over 50 leading international institutions in 19 countries including top-tier academic and hospital research groups, major pharmaceutical and agricultural companies. "We are delighted to have been supported by Debiopharm Innovation Fund and Tesi in this new financing round," said Tero Silvola, CEO at BC Platforms. "This funding will enable us to progress to our next stage of expansion and to launch our new knowledge based solutions for R&D customers worldwide. Debiopharm’s experience in drug development will provide us with invaluable insight as we launch this major new initiative." BC Platforms’ vision is to provide the world’s leading analytics platform for healthcare and industry, with access by 2020 to over 5 million subjects’ diverse genomic and clinical data and samples consolidated from a global network of biobanks - organized repositories of human biological material and associated data stored for research purposes. BC Platforms partners with biobanks to aggregate these data for analysis, and to provide solutions for customers across all therapeutic areas.


BC Platforms, a world leader in genomic data management solutions, today announces that it has closed a $USD 10 million financing round. The round was led by Debiopharm Innovation Fund in conjunction with Tesi, a Finnish venture capital and private equity company, and was supported by BC Platforms' existing investors. BC Platforms will use the funds to launch new technologies in 2017 integrating complex clinical and genomic data in order to deliver precision medicine and clinical patient benefits, as well as to grow its existing genomic data management software business worldwide. To date, the company has established partnerships with over 50 enterprise level Healthcare units and biobanks globally in 19 countries representing more than 2 million subjects. BC Platforms' vision is to provide the world's leading analytics platform for healthcare and industry, with access by 2020 to over 5 million subjects' diverse genomic and clinical data and samples consolidated from a global network of biobanks. Biobanks are organized repositories of human biological material and associated data stored for research purposes. BC Platforms partners with biobanks to aggregate these data for analysis to provide transformative solutions for customers across all therapeutic areas and along the entire product development life cycle. Tero Silvola, CEO at BC Platforms, said: 'We are delighted to have been supported by Debiopharm Innovation Fund and Tesi in this new financing round. This funding will enable us to progress to our next stage of expansion and to launch our new knowledge based solutions for R&D customers worldwide. Debiopharm's experience in drug development will provide us with invaluable insight as we launch this major new initiative.' Tanja Dowe, Head of Debiopharm Innovation Fund, said: "We see big data as a core asset in research and development. We are excited to have invested in BC Platforms and look forward to working with them to unlock the potential of big data to dramatically improve R&D productivity and provide clinical benefits to patients. BC Platforms fits directly with our fund's vision to invest in innovative companies that change the way we develop drugs and treat patients. Joni Karsikas, Investment Manager at Tesi, commented: 'We are dedicated supporters of innovation and believe that health technology is going to be a key growth opportunity for Finland. We are very pleased to be supporting BC Platforms, who are a leader in the field of genomic data management, in their next stage of transformative growth.' BC Platforms is a world leader in providing powerful genomic data management solutions to address some of the biggest healthcare challenges today by leveraging the convergence of genomics and healthcare information technologies. Our high performing genomic data management platform enables flexible data integration, secure analysis and interpretation of molecular and clinical information. BC Platforms' vision is to revolutionize decision making in drug development to bring clinical benefits to patients. Founded in 1997, the Company has a strong scientific heritage underpinned by 20 years of working in close collaboration with a network of leading researchers, developers, manufacturers and vendors. We currently provide solutions to over 50 leading international institutions in 19 countries including top-tier academic and hospital research groups, major pharmaceutical and agricultural companies.  Our management team consists of industry leaders with over 100 years of combined experience in life sciences, computational biology and industrial technology.  BC Platforms has global operations with its headquarters in Basel, Switzerland, research and development located in Helsinki, Finland, and sales and marketing based in London, Boston, and Vancouver. For more information, please visit http://www.bcplatforms.com or follow us on Twitter @BCPlatforms. Part of Debiopharm Group™ - a Swiss-headquartered global biopharmaceutical group including five companies active in the life science areas of drug development, GMP manufacturing of proprietary drugs, diagnostic tools and investment management - Debiopharm Innovation Fund's mission is to invest in companies developing innovative therapeutics, diagnostics and smart data solutions that change the way we develop drugs and treat patients. Since 2008, the company has invested nearly USD 100 million and led 10 out of the 14 last investment rounds in its portfolio companies. For more information, please visit http://www.debiopharm.com We are on Twitter. Follow us @DebiopharmNews at http://twitter.com/DebiopharmNews Tesi (Finnish Industry Investment Ltd) is a venture capital and private equity company that accelerates companies' success stories by investing in them directly and via funds. Tesi always invests together with other investors, providing them with access to high quality deal flow in Finland. Our investments under management total 1 billion euros and we have altogether 723 companies in portfolio. http://www.tesi.fi | @TesiFII


A ce jour, la société a établi des partenariats au niveau entreprise avec plus de 50 unités de soins et biobanques dans 19 pays, représentant plus de 2 millions d'individus. La vision de BC Platforms consiste à fournir la meilleure plateforme mondiale pour les services de santé et l'industrie, qui donnera accès d'ici 2020 aux données génomiques et cliniques variés ainsi qu'aux échantillons de plus de 5 millions d'individus réunis par un réseau mondial de biobanques. Les biobanques sont des entrepôts organisés de matériel biologique humain et de données associées stockés à des fins de recherche. BC Platforms établit des partenariats avec des biobanques dans le but de regrouper ces données pour analyse afin de proposer aux clients des solutions novatrices dans tous les domaines thérapeutiques et sur l'intégralité du cycle de développement des produits. «Nous considérons le « big data » comme un atout essentiel pour la recherche et développement, a déclaré Tanja Dowe, Head of Debiopharm Innovation Fund. Nous nous félicitons d'avoir investi dans BC Platforms et avons hâte de travailler avec cette entreprise pour libérer le potentiel de « big data » afin d'améliorer de manière spectaculaire la productivité de la R&D et d'apporter des bénéfices cliniques aux patients. BC Platforms s'inscrit directement dans la vision de notre fonds d'investir dans des sociétés innovantes qui changent la manière dont nous développons des médicaments et traitons les patients.» BC Platforms est un leader mondial qui fournit des solutions puissantes de gestion de données génomiques destinées à relever certains des plus grands défis de santé actuels en tirant parti de la convergence de la génomique et des technologies d'information de santé. Notre plateforme hautement performante de gestion de données génomiques permet une intégration souple des données, une analyse sécurisée et une interprétation des informations moléculaires et cliniques. BC Platforms a pour vision de révolutionner la prise de décisions dans le développement des médicaments afin d'offrir des bénéfices cliniques aux patients. Fondée en 1997, la Société possède un solide patrimoine scientifique étayé par 20 années de collaboration étroite avec un réseau composé de chercheurs, développeurs, fabricants et prestataires renommés. Nous fournissons actuellement des solutions à plus de 50 institutions internationales de premier plan dans 19 pays, notamment à des groupes de recherche universitaires et hospitaliers de haut niveau et à de grandes sociétés pharmaceutiques et agricoles. Notre équipe de direction est composée de leaders du secteur qui totalisent plus de 100 années d'expérience combinée en sciences de la vie, biologie computationnelle et technologie industrielle. BC Platforms est une entreprise internationale dont le siège social est situé à Bâle (Suisse), la recherche et développement à Helsinki (Finlande) et les ventes et le marketing à Londres, Boston et Vancouver. Pour plus d'informations, veuillez consulter le site Internet http://www.bcplatforms.com ou nous suivre sur Twitter @BCPlatforms. Membre de Debiopharm Group™, groupe international dont le siège social se trouve en Suisse, composé de cinq sociétés biopharmaceutiques actives dans les domaines des sciences de la vie que sont le développement de médicaments, la fabrication de médicaments exclusifs selon les BPF et les outils de diagnostic, ainsi que dans la gestion des investissements, Debiopharm Innovation Fund a pour mission d'investir dans des sociétés développant des produits thérapeutiques, des diagnostics et des solutions de smart data novateurs qui changent la manière dont nous développons les médicaments et traitons les patients. Depuis 2008, la société a investi près de USD 100 millions et mené 10 des 14 derniers cycles de financement des entreprises de son portefeuille. Pour plus d'informations, veuillez consulter notre site Internet http://www.debiopharm.com Tesi (Finnish Industry Investment Ltd) est une société de capital-risque et de capital-investissement qui accélère la réussite des entreprises dans lesquelles elle investit directement et via des fonds. Tesi investit toujours avec d'autres investisseurs, leur donnant accès à un flux d'opérations de haute qualité en Finlande. Le total de nos investissements sous gestion s'élève à 1 milliard d'euros et notre portefeuille est composé de 723 sociétés. http://www.tesi.fi | @TesiFII


Patent
Aurigene Discovery Technologies Ltd. and Debiopharm S.A. | Date: 2011-02-17

The present invention relates to substituted aromatic bicyclic compounds containing pyrimidine and pyridine rings of formula (I) having the structure as well as pharmaceutically acceptable salts thereof. The compounds of the present invention are useful as tyrosine kinase inhibitors, preferably SRC family kinases (SFKs) inhibitors, in particular as multi SFK/JAK. kinases inhibitors and even preferably as dual c-SRC/JAK kinases inhibitors, thereby inhibiting the STAT3 activation and therefore abnormal growth of particular cell types. Notably, the compounds of the present invention are useful for the treatment or inhibition of certain diseases that are the result of deregulation of STAT3.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH.2010.2.4.1-6 | Award Amount: 3.90M | Year: 2011

Pancreatic ductal adenocarcinoma (PDAC) causes 34000 deaths in the EU every year. Conventional cancer treatments have close to no impact on this disease. As a result, almost all patients diagnosed with PDAC develop metastases and eventually die. Given this poor outlook, the search for new therapeutics is mandatory. These will have to target relevant cancer pathways and be designed based on the available knowledge on the genetic alterations that characterize this malignancy. We propose to build a team composed of clinicians, translational cancer researchers, chemists, and two pharmaceutical enterprises, to synthesize and implement new drugs for PDAC. The focus of the participants in this project will be on pathways and cellular functions broadly involved in PDAC metastasis and immune escape. These drugs are meant to work through diverse and novel modes of action and will be validated using genetically engineered PDAC mouse models that we have established at the Center for Integrated Oncology in Bonn. By creating and exploring diverse classes of compounds capable of arresting tumor growth and of interfering with its metastatic spread, this project will deliver a high number of new molecules with potential as anticancer therapeutics. In particular, our consortium will produce new indoleamine 2,3-dioxygenase-2 (IDO2) inhibitors, galectin-3 inhibitors, edelfosine analogues, inhibitors of the Hippo signaling pathway, alpha-mannosidase inhibitors, SIRT6 inhibitors, and therapeutics acting by synthetic lethality. For compounds with strong proof-of-concept activity, our consortium will perform the Investigational New Drug (IND)-Enabling Studies, with the goal of delivering a new drug ready to be tested clinically by the end of the project. The PANACREAS project is meant to help find better treatments for PDAC, boost research on this form of cancer in the EU, and open new avenues for scientific and technological innovation.


Janssens S.,Ghent University | Tinel A.,Debiopharm SA
Cell Death and Differentiation | Year: 2012

P53-induced protein with a death domain (PIDD) was cloned as a death domain (DD)-containing protein whose expression is induced by p53. It was later described as the core of a molecular platform-activating caspase-2, named the PIDDosome. These first results pointed towards a role for PIDD in apoptosis, in response to DNA damage. Identification of new PIDDosome complexes involved in DNA repair and nuclear factor-κB signaling challenged this early concept. PIDD functions are growing as new complexes and new interaction partners are being discovered, and as additional functions are being revealed. A fascinating feature of PIDD lies within its complex and tight regulation mechanisms, which allow the molecule to fine-tune its different functions: from transcriptional regulation to the expression of different isoforms, and from the interaction with regulatory proteins to an ingenious post-translational cleavage mechanism generating various active fragments with specific functions. Further studies still need to be carried out to provide answers to many unresolved issues and to reconcile conflicting results. This review aims at providing an overview of the current PIDD knowledge status. © 2012 Macmillan Publishers Limited All rights reserved.


Patent
Catholic University of Leuven and Debiopharm SA | Date: 2013-12-23

Assays for characterization of genotypic mutations of Hepatitis C Virus (HCV) showing a resistance to anti-HCV drugs.


Patent
Debiopharm S.A. | Date: 2014-08-27

The present invention relates to an indole derivative of structural formula (I), or a pharmaceutically acceptable salt or solvate thereof, which is useful as a direct AMPK activator, to uses and methods of use thereof, and to pharmaceutical compositions comprising such compound.


Patent
Debiopharm S.A. and Novartis | Date: 2011-12-12

The invention provides lipid-based pharmaceutical compositions comprising alisporivir.


Patent
Novartis and Debiopharm S.A. | Date: 2016-05-12

The invention provides lipid-based pharmaceutical compositions comprising alisporivir.

Loading Debiopharm SA collaborators
Loading Debiopharm SA collaborators