Siti H.N.,National University of Malaysia |
Siti H.N.,Darul Iman University, Malaysia |
Kamisah Y.,National University of Malaysia |
Kamsiah J.,National University of Malaysia
Vascular Pharmacology | Year: 2015
The concept of mild chronic vascular inflammation as part of the pathophysiology of cardiovascular disease, most importantly hypertension and atherosclerosis, has been well accepted. Indeed there are links between vascular inflammation, endothelial dysfunction and oxidative stress. However, there are still gaps in our understanding regarding this matter that might be the cause behind disappointing results of antioxidant therapy for cardiovascular risk factors in large-scale long-term randomised controlled trials. Apart from the limitations of our knowledge, limitations in methodology and assessment of the body's endogenous and exogenous oxidant-antioxidant status are a serious handicap. The pleiotropic effects of antioxidant and anti-inflammation that are shown by some well-established antihypertensive agents and statins partly support the idea of using antioxidants in vascular diseases as still relevant. This review aims to provide an overview of the links between oxidative stress, vascular inflammation, endothelial dysfunction and cardiovascular risk factors, importantly focusing on blood pressure regulation and atherosclerosis. In view of the potential benefits of antioxidants, this review will also examine the proposed role of vitamin C, vitamin E and polyphenols in cardiovascular diseases as well as the success or failure of antioxidant therapy for cardiovascular diseases in clinical trials. © 2015 Elsevier Inc.
Jusoh A.,University of Malaysia, Terengganu |
Hartini W.J.H.,University of Malaysia, Terengganu |
Ali N.,University of Malaysia, Terengganu |
Endut A.,Darul Iman University, Malaysia
Bioresource Technology | Year: 2011
In this batch study, the adsorption of malathion by using granular activated carbon with different parameters due to the particle size, dosage of carbons, as well as the initial concentration of malathion was investigated. Batch tests were carried out to determine the potential and the effectiveness of granular activated carbon (GAC) in removal of pesticide in agricultural run off. The granular activated carbon; coconut shell and palm shells were used and analyzed as the adsorbent material. The Langmuir and Freundlich adsorption isotherms models were applied to describe the characteristics of adsorption behavior. Equilibrium data fitted well with the Langmuir model and Freundlich model with maximum adsorption capacity of 909.1. mg/g. The results indicate that the GAC could be used to effectively adsorb pesticide (malathion) from agricultural runoff. © 2010 Elsevier Ltd.
Mohammed J.S.,Darul Iman University, Malaysia
Progress in Oceanography | Year: 2015
A better understanding of the vast range of plankton and their interactions with the marine environment would allow prediction of their large-scale impact on the marine ecosystem, and provide in-depth knowledge on pollution and climate change. Numerous technologies, especially lab-on-a-chip microsystems, are being used to this end. Marine biofouling is a global issue with significant economic consequences. Ecofriendly polymer nanotechnologies are being developed to combat marine biofouling. Furthermore, nanomaterials hold great potential for bioremediation and biofuel production. Excellent reviews covering focused topics in plankton research exist, with only a handful discussing both micro- and nanotechnologies. This work reviews both micro- and nanotechnologies applied to broad-ranging plankton research topics including flow cytometry, chemotaxis/toxicity assays, biofilm formation, marine antifouling/fouling-release surfaces and coatings, green energy, green nanomaterials, microalgae immobilization, and bioremediation. It is anticipated that developments in plankton research will see engineered exploitation of micro- and nanotechnologies. The current review is therefore intended to promote micro-/nanotechnology researchers to team up with limnologists/oceanographers, and develop novel strategies for understanding and green exploitation of the complex marine ecosystem. © 2015 Elsevier Ltd.
Lua P.L.,Darul Iman University, Malaysia
Journal of Complementary and Integrative Medicine | Year: 2011
Although the popularity of complementary indigenous Malay therapies (CIMT) in general healthcare is undeniable in the Malaysian context today, their usage within the palliative care scenarios remains unexplored. Our study was specifically embarked to determine CIMT's usage pattern, reasons, attitudes, beliefs, perceptions and health-related quality of life (HRQoL) differences (users vs. non-users) in a sample of hospice-based palliative patients in Selangor, Malaysia. From the 39 consenting patients (mean age = 56 years; female = 56.4 percent; Malay = 53.8 percent), 38.5 percent were users of CIMT. Dried medicinal roots, herbs and sea cucumber products were the most preferred types of CIMT (53.3 percent). The most common reason cited for usage was because these were "easier and simpler to be administered" (46.7 percent). Although users' attitudes, beliefs and perceptions were more favourable than the non-users, between 30.0-73.3 percent of users remained unsure or had no knowledge regarding CIMT. They also exhibited significantly poorer Physical Symptoms than the non-users (p=0.006), a probable motive for seeking CIMT in the first place. Despite the small sample size, the findings provided some insight into the role of CIMT especially with regard to usage trends and overall well-being among the terminally-ill, of which healthcare professionals should constantly be vigilant of amidst their routine care responsibilities. Copyright © 2011 The Berkeley Electronic Press. All rights reserved.
Loganathan N.,Darul Iman University, Malaysia |
Shahbaz M.,COMSATS Institute of Information Technology |
Taha R.,University of Malaysia, Terengganu
Renewable and Sustainable Energy Reviews | Year: 2014
This paper explores how carbon taxation and economic growth affect environment hazards in Malaysia using time series data over the period 1974-2010. We applied cointegration and causality approaches to determine the long-term cointegration and direction of causal relationship between these variables. Based on the results, we found the cointegration relationship between the variables. Furthermore, we noted that although Kuznets' theory, i.e. inverted-U shaped curve between economic growth and CO2 emissions is valid for Malaysia, the carbon taxation policy is ineffective to control CO 2 emissions. The causality analysis revealed that there is a bidirectional relationship between carbon tax and CO2 emissions. Economic growth Granger causes CO2 emissions and carbon tax Granger causes economic growth. To enhance the awareness concerning pollution issues, governments should rely on alternative instruments that may give benefit to the taxpayers and reduce pollution, which is the pivotal issue to be tackled globally. © 2014 Elsevier Ltd.