Danish Emergency Management Agency

Birkerod, Denmark

Danish Emergency Management Agency

Birkerod, Denmark

The Danish Emergency Management Agency is a Danish governmental agency under the Ministry of Defence. Its principal task is to manage an operational part who work out of six Emergency Management Centres, and administrative and legalizing part, who supervises the national and municipal rescue preparedness and advices the authorities on matters of preparedness. DEMA works in closely structured co-operation with the EU, UN and several neighbouring countries.DEMA is capable of deploying abroad on request from another state or an international organisation. The decision to render assistance is taken in co-counsel with the Danish Foreign Ministry. DEMA can give support in instances of natural disasters and accidents, technological events and crises and civil wars. It is able to react quickly in acute situations and leave its home base within hours on smaller missions, and have the ability to deploy a mobile hospital in only 24 hours. Wikipedia.

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Mariager T.P.,Copenhagen University | Madsen P.V.,Aarhus University Hospital | Ebbehoj N.E.,Copenhagen University | Schmidt B.,Danish Emergency Management Agency | Juhl A.,Aarhus University Hospital
Clinical Toxicology | Year: 2013

This is a case of severe chemical burns following prolonged accidental exposure to a glyphosate-surfactant herbicide. The patient developed local swelling, bullae and exuding wounds. Neurological impairment followed affecting finger flexion and sensation with reduced nerve conduction. Imaging revealed oedema of the soft tissue and juxta-articular osteopenia, and a causal relationship to exposure is suggested. © 2013 Informa Healthcare USA, Inc.

Mithander A.,Copenhagen University | Goen T.,Friedrich - Alexander - University, Erlangen - Nuremberg | Felding G.,Danish Emergency Management Agency | Jacobsen P.,Copenhagen University
Journal of Occupational Medicine and Toxicology | Year: 2017

Preservation of museum objects with inorganic arsenic compounds and contamination of the surroundings has previously been documented. The present study addresses the exposure of museum staff by measuring arsenicals in urine. After 1 week without exposure, urinary samples were taken before and after handling of preserved skins and analysed by HPLC-ICP-MS for inorganic arsenic, arsenic metabolites and arsenobetaine. The sum of inorganic arsenic and metabolites was an index of exposure. Information about work and seafood intake was obtained by questionnaire. One out of five subjects had a work-related rise in the exposure index of 18.1 μg As/L to a post-exposure level of 37.1 μg As/L. Four subjects had no certain exposure-related increase in the index. The study indicates that museum staff may be exposed to arsenic from handling arsenic-preserved objects and supports the use of specified arsenic analysis to avoid interference from organic arsenic. © 2017 The Author(s).

Dowdall M.,Norwegian Radiation Protection Authority | Mattila A.,Radiation and Nuclear Safety Authority | Rameback H.,Swedish Defence Research Agency | Aage H.K.,Danish Emergency Management Agency | Palsson S.E.,Icelandic Radiation Safety Authority
Journal of Radioanalytical and Nuclear Chemistry | Year: 2015

The capabilities of a number of national reach-back entities in situations involving possible interdiction of nuclear materials was assessed. The assessment was conducted as a training exercise using simulated gamma spectra of a range of materials typical of those that may trigger border alarms, some of which included nuclear materials of various types. Responses indicated that the majority of participants were in a position to highlight the potential presence of such materials even in the presence of shielding or masking materials. Cases where participants had greater difficulty in indicating the presence of nuclear material involved materials with which the majority of participants were unfamiliar. Even though conducted as an exercise, results indicate that national reach-back entities can perform adequately but further enhancement of capabilities through training assessments may increase the efficacy of the expert assistance they provide to first responders. © 2014, Akadémiai Kiadó, Budapest, Hungary.

Lahtinen J.,Radiation and Nuclear Safety Authority | Aage H.K.,Danish Emergency Management Agency | Ammann M.,Radiation and Nuclear Safety Authority | Dyve J.E.,Norwegian Radiation Protection Authority | And 3 more authors.
Radioprotection | Year: 2010

Decision makers must react in a prompt and appropriate manner in various emergency situations. The bases for decisions are often predictions produced with decision support systems (DSS). Actual radiation measurement data can be used to improve the reliability of the predictions. Data assimilation is an important link between model calculations and measurements and thus decreases the overall uncertainty of the DSS predictions. However, different aspects have to be taken into account for the optimal use of the data assimilation technique: different countries may have differing measurement strategies and systems as well as differing calculation models. The scenario and the amount and composition of radionuclides released may vary. In this paper we analyse the situation during and after an accident and draw up a list of recommendations that can help modellers to take into account the measurements that are best suited for data assimilation. © EDP Sciences, 2010.

Dowdall M.,Norwegian Radiation Protection Authority | Smethurst M.A.,University of Exeter | Watson R.,Geological Survey of Norway | Mauring A.,Norwegian Radiation Protection Authority | And 3 more authors.
Journal of Environmental Radioactivity | Year: 2012

In recent years car-borne gamma spectrometry has expanded from its role as a geological survey platform to being a useful asset in searching for orphan sources and for surveying in the aftermath of an incident involving the release of radioactive materials. The opportunities for gaining practical experience in the field however are limited by cost considerations and practicability. These limitations are exacerbated by the fact that field data can differ significantly from data generated in the laboratory. As a means of exercising existing emergency measuring/surveying capability and introducing car-borne measurements to a larger group, a virtual exercise was devised. The exercise ORPEX (Orphan Sources and Fresh Fallout Virtual Exercise in Mobile Measurement) featured two typical emergency scenarios: a search for orphan sources and surveying to delineate fallout from a local release point. Synthetic spectral data were generated for point sources and inserted into genuine car-borne measurement data. Participants were presented with a typical software tool and data and were asked to report source locations and isotopes within a time limit. In the second scenario, synthetic data representing fallout from a local fire involving radioactive material were added to real car-borne data, participants being asked to produce maps identifying and characterising the regions of contamination. Fourteen individual organisations from seven different countries supplied results which indicated that for strong sources of isotopes with simple spectra featuring high energy peaks, location and identification was not a problem. Problems arose for isotopes with low energy signals or that presented a weak signal even when visible for extended periods. Experienced analysts tended to perform better in identification of sources irrespective of experience with mobile measurements whereas those with experience in such measurements were more confident in providing more precise estimates of location. The results indicated the need for the inclusion of less frequently encountered sources in field exercise related to mobile measurements. © 2011 Elsevier Ltd.

Hedlund F.H.,Cowi A/S | Hedlund F.H.,Technical University of Denmark | Nielsen M.F.,Danish Emergency Management Agency | Mikkelsen S.H.,Cowi A/S | Kragh E.K.,Cowi A/S
Safety Science | Year: 2014

At a brewery in 1997, an operator confused filling nozzles for two commonly used acid cleaning agents and transferred nitric acid into a tank with P3, a proprietary phosphoric acid based cleaner that also contained 5-15% isopropanol. 10-15. min later the mixture exploded violently. The stainless steel tank disintegrated with such force that fragments lodged in walls of concrete. The explosion ravaged the cellar, destroyed equipment, blew out a masonry wall and released large amounts of nitrous oxide fumes. Likely, 62% nitric acid (CAS 7697-37-2) and isopropanol (2-propanol, CAS 67-63-0) reacted to produce isopropyl nitrate (nitric acid 1-methylethyl ester, CAS 1712-64-7), a rocket propellant. It is argued that the accident has broad learning potential because of the widespread usage of the two chemicals across industries, the innocent nature of the human error and the severity of the consequence. A review 15. years later of lessons learned finds that information dissemination has followed a tradition of informal meetings in small industry sector associations but impact is unclear. There is no useful mention of the accident in open sources. Although the Danish Working Environment Authority took the brewery to court for negligence, they did not report or investigate the accident, or attempt to disseminate information available to them. Today, the general literature is silent on the explosion hazards of mixing the two chemicals. The paper argues that without institutional support, learning opportunities are missed and broader cross-sector learning is limited or non-existent. © 2014 Elsevier Ltd.

Rohrich C.R.,Fraunhofer Institute for Molecular Biology and Applied Ecology | Rohrich C.R.,AB SCIEX Germany GmbH | Jaklitsch W.M.,University of Vienna | Voglmayr H.,University of Vienna | And 9 more authors.
Fungal Diversity | Year: 2014

Approximately 950 individual sequences of non-ribosomally biosynthesised peptides are produced by the genus Trichoderma/Hypocrea that belong to a perpetually growing class of mostly linear antibiotic oligopeptides, which are rich in the non-proteinogenic α-aminoisobutyric acid (Aib). Thus, they are comprehensively named peptaibiotics. Notably, peptaibiotics represent ca. 80 % of the total inventory of secondary metabolites currently known from Trichoderma/Hypocrea. Their unique membrane-modifying bioactivity results from amphipathicity and helicity, thus making them ideal candidates in assisting both colonisation and defence of the natural habitats by their fungal producers. Despite this, reports on the in vivo-detection of peptaibiotics have scarcely been published in the past. In order to evaluate the significance of peptaibiotic production for a broader range of potential producers, we screened nine specimens belonging to seven hitherto uninvestigated fungicolous or saprotrophic Trichoderma/Hypocrea species by liquid chromatography coupled to electrospray high resolution mass spectrometry. Sequences of peptaibiotics found were independently confirmed by analysing the peptaibiome of pure agar cultures obtained by single-ascospore isolation from the specimens. Of the nine species examined, five were screened positive for peptaibiotics. A total of 78 peptaibiotics were sequenced, 56 (= 72 %) of which are new. Notably, dihydroxyphenylalaninol and O-prenylated tyrosinol, two C-terminal residues, which have not been reported for peptaibiotics before, were found as well as new and recurrent sequences carrying the recently described tyrosinol residue at their C-terminus. The majority of peptaibiotics sequenced are 18- or 19-residue peptaibols. Structural homologies with ‘classical representatives’ of subfamily 1 (SF1)-peptaibiotics argue for the formation of transmembrane ion channels, which are prone to facilitate the producer capture and defence of its substratum. © 2014, The Author(s).

PubMed | Danish Emergency Management Agency, University of Vienna, Justus Liebig University, Fraunhofer Institute for Molecular Biology and Applied Ecology and 2 more.
Type: Journal Article | Journal: Fungal diversity | Year: 2015

Approximately 950 individual sequences of non-ribosomally biosynthesised peptides are produced by the genus

Malmen Y.,VTT Technical Research Center of Finland | Joki H.,VTT Technical Research Center of Finland | Jensen J.S.,Danish Emergency Management Agency
WIT Transactions on Information and Communication Technologies | Year: 2014

There are many elements to chemical, biological, radiological and nuclear (CBRN) crisis management (handheld detectors, decontamination methods, personal protective equipment, standard operating procedures, emergency managements systems, training programmes, etc.). In the ongoing CATO project (EU FP7: 'A comprehensive holistic answer centred on an integrated CBRN toolbox'), these different elements are pulled together in an overall approach to CBRN preparedness and resilience. CATO proposes a comprehensive holistic answer to CBRN crisis management centred on an integrated CBRN toolbox. CATO starts from the 'puzzle pieces' of the current situation and works within the existing organisational limitations. In order to complete the 'toolbox puzzle', CATO is also defining and developing new tools. A new risk assessment tool has been developed as part of CATO's Chemical Knowledge Base. This tool tackles one of the key differences between a malicious act and an industrial accident: the unknown identity of the chemical released. The tool allows an unknown chemical agent used in a chemical attack to be categorised based on a limited amount of data. This paper describes the rationale behind the new risk analysis tool and briefly discusses the content given for various chemical groups and how it has been tailored to meet the needs of five user groups: the policy-makers, the incident coordinators, the health care personnel, the responders, and the population. The development work has been carried out by VTT Technical Research Centre of Finland in cooperation with the Danish Emergency Management Agency (DEMA). © 2014 WIT Press.

Klitgaard A.,Technical University of Denmark | Iversen A.,Technical University of Denmark | Iversen A.,Danish Emergency Management Agency | Andersen M.R.,Technical University of Denmark | And 3 more authors.
Analytical and Bioanalytical Chemistry | Year: 2014

In natural-product drug discovery, finding new compounds is the main task, and thus fast dereplication of known compounds is essential. This is usually performed by manual liquid chromatography-ultraviolet (LC-UV) or visible light-mass spectroscopy (Vis-MS) interpretation of detected peaks, often assisted by automated identification of previously identified compounds. We used a 15 min high-performance liquid chromatography-diode array detection (UHPLC-DAD)-high-resolution MS method (electrospray ionization (ESI)+ or ESI-), followed by 10-60 s of automated data analysis for up to 3000 relevant elemental compositions. By overlaying automatically generated extracted-ion chromatograms from detected compounds on the base peak chromatogram, all major potentially novel peaks could be visualized. Peaks corresponding to compounds available as reference standards, previously identified compounds, and major contaminants from solvents, media, filters etc. were labeled to differentiate these from compounds only identified by elemental composition. This enabled fast manual evaluation of both known peaks and potential novel-compound peaks, by manual verification of: the adduct pattern, UV-Vis, retention time compared with log D, co-identified biosynthetic related compounds, and elution order. System performance, including adduct patterns, in-source fragmentation, and ion-cooler bias, was investigated on reference standards, and the overall method was used on extracts of Aspergillus carbonarius and Penicillium melanoconidium, revealing new nitrogen-containing biomarkers for both species. © 2014 The Author(s).

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