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Chen Y.,Dallas Technologies | Lask T.A.,Vanderbilt University | Mei Q.,University of Michigan | Chen Q.,Vanderbilt University | And 7 more authors.
BMC Medical Informatics and Decision Making | Year: 2017

Background: Active learning (AL) has shown the promising potential to minimize the annotation cost while maximizing the performance in building statistical natural language processing (NLP) models. However, very few studies have investigated AL in a real-life setting in medical domain. Methods: In this study, we developed the first AL-enabled annotation system for clinical named entity recognition (NER) with a novel AL algorithm. Besides the simulation study to evaluate the novel AL algorithm, we further conducted user studies with two nurses using this system to assess the performance of AL in real world annotation processes for building clinical NER models. Results: The simulation results show that the novel AL algorithm outperformed traditional AL algorithm and random sampling. However, the user study tells a different story that AL methods did not always perform better than random sampling for different users. Conclusions: We found that the increased information content of actively selected sentences is strongly offset by the increased time required to annotate them. Moreover, the annotation time was not considered in the querying algorithms. Our future work includes developing better AL algorithms with the estimation of annotation time and evaluating the system with larger number of users. © 2017 The Author(s).


Yang K.,University of Texas at Dallas | Grant J.C.,University of Texas at Dallas | Lamey P.,University of Texas at Dallas | Joshi-Imre A.,University of Texas at Dallas | And 3 more authors.
Advanced Functional Materials | Year: 2017

This study presents a new 3D printing process, the Diels-Alder reversible thermoset (DART) process, and a first generation of printable DART resins, which exhibit thermoset properties at use temperatures, ultralow melt viscosity at print temperatures, smooth part surface finish, and as-printed isotropic mechanical properties. This study utilizes dynamic covalent chemistry based on reversible furan-maleimide Diels-Alder linkages in the polymers, which can be decrosslinked and melt-processed during printing between 90 and 150 °C, and recrosslinked at lower temperatures to their entropically favored state. This study compares the first generation of DART materials to commonly 3D printed high-toughness thermoplastics. Parts printed from typical fused filament fabrication compatible materials exhibit anisotropy of more than 50% and sometimes upward of 98% in toughness when deformed along the build direction, while the first generation of DART materials exhibit less than 4% toughness reduction when deformed along the build direction. At room temperature, the toughest DART materials exhibit baseline toughness of 18.59 ± 0.91 and 18.36 ± 0.57 MJ m-3 perpendicular and parallel to the build direction, respectively. DART printing will enable chemists, polymer engineers, materials scientists, and industrial designers to translate new robust materials possessing targeted thermomechanical properties, multiaxial toughness, smooth surface finish, and low anisotropy. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Ellis T.W.,Dallas Technologies | Bevans S.,Quemetco
Pb Zn 2010 - Lead-Zinc 2010 Symposium, Held in Conjunction with COM 2010 | Year: 2010

Quemetco, City of Industry, California, an Eco-Bat battery recycling facility, maintains state of the art emissions control technology producing 100,000+ metric tons of lead/lead alloys primarily from spent lead acid batteries controlling emission streams of the feed dryer, reverberatory and electric arc furnaces, and pyro-metallurgical refinery. In 2008, Quemetco introduced the most advanced air emissions treatment system significantly reducing the already low emissions installing both a regenerative thermal oxidizer (RTO) reducing hydrocarbon emissions, and a wet electrostatic precipitator (WESP) lowering lead, arsenic, cadmium and nickel emissions. Quemetco's accomplishment demonstrates a new maximum available control technology (MACT) for secondary smelters.


Bagchi D.,Sparsha Learning Technologies | Kaushik K.,Sparsha Learning Technologies | Kapoor B.,Dallas Technologies
Proceedings of the 3rd Interdisciplinary Engineering Design Education Conference, IEDEC 2013 | Year: 2013

Online learning is fast becoming a preferred medium of learning. It is estimated that 6 million college students took at least one online course last year. Online learning in technical education is primarily delivered through pre-recorded videos. We will discuss a virtual learning system in the context of electronics engineering education. This learning system models the circuits as well as the instruments that are typically used in the labs to allow students to carry out the experiments in a virtual environment. We have extended the concept further to allow students to carry out the experiments on the web-browsers and devices of their choice. The simulations themselves are carried out utilizing cloud computing infrastructure such as those provided by Amazon and Microsoft while the use focuses on putting the experiments. © 2013 IEEE.


Mahmood M.A.I.,Dallas Technologies | Ali W.,Dallas Technologies | Adnan A.,University of Texas at Arlington | Iqbal S.M.,Dallas Technologies | Iqbal S.M.,University of Texas at Arlington
Journal of Physical Chemistry B | Year: 2014

Biomarker-binding nucleotide sequences, like aptamers, have gained recent attention in cancer cell isolation and detection works. Self-assembly and 3D conformation of aptamers enable them to selectively capture and bind diseased cells and related biomarkers. One mode of utilizing such an extraordinary selective property of the aptamers is by grafting these in nanopores. Coating the inside walls of the nanopore with biomarker specific ligands, like DNA, changes the statistics of the dynamic translocation events. When the target protein passes through the nanopore, it interacts with ligand coated inside the nanopore, and the process alters the overall potential energy profile which is essentially specific to the protein detected. The fundamental goal in this process is to ensure that these detection motifs hold their structure and functionality under applied electric field and experimental conditions. We report here all-atom molecular dynamics simulations of the effects of external electric field on the 3D conformation of such DNA structures. The simulations demonstrate how the grafted moieties affect the translocation time, velocity, and detection frequency of the target molecule. We also investigated a novel case of protein translocation, where DNA is prebound to the protein. As model, a thrombin-specific G-quartet and thrombin pair was used for this study. © 2014 American Chemical Society.


Evanoo J.,Dallas Technologies | Cameron D.,Dallas Technologies
Healthcare financial management : journal of the Healthcare Financial Management Association | Year: 2010

Capital equipment strategic planning (CESP) is a data-driven method that can be used for evaluating a hospital's existing equipment in light of its business goals and budget to develop an unbiased multiyear plan for replacing aging equipment. The foundation for CESP is a rigorous technology assessment of all clinical equipment items that represent a significant cost to replace (above a certain threshold). Armed with the data gleaned from this technology assessment, hospital executives can begin to make informed decisions about where to allocate capital spending to replace mission-critical clinical equipment.


Jones J.B.,Dallas Technologies
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2016

The advent of laser technology has been a key enabler for industrial 3D printing, known as Additive Manufacturing (AM). Despite its commercial success and unique technical capabilities, laser-based AM systems are not yet able to produce parts with the same accuracy and surface finish as CNC machining. To enable the geometry and material freedoms afforded by AM, yet achieve the precision and productivity of CNC machining, hybrid combinations of these two processes have started to gain traction. To achieve the benefits of combined processing, laser technology has been integrated into mainstream CNC machines - effectively repurposing them as hybrid manufacturing platforms. This paper reviews how this engineering challenge has prompted beam delivery innovations to allow automated changeover between laser processing and machining, using standard CNC tool changers. Handling laser-processing heads using the tool changer also enables automated change over between different types of laser processing heads, further expanding the breadth of laser processing flexibility in a hybrid CNC. This paper highlights the development, challenges and future impact of hybrid CNCs on laser processing. © 2016 SPIE.


David Prengaman R.,Dallas Technologies | Ellis T.,Dallas Technologies | Mirza A.,Dallas Technologies
Pb Zn 2010 - Lead-Zinc 2010 Symposium, Held in Conjunction with COM 2010 | Year: 2010

It has been 10 years since RSR Technologies introduced a new rolled anode for Zinc Electrowinning. The anode contains calcium and significantly less silver than the traditional cast or rolled lead silver anodes. The anodes are rolled to produce uniform dispersion of calcium and silver. These anodes have much higher mechanical properties than lead-silver which makes them more resistant to deformation. The calcium allows the anode to condition in several days. The anodes have been extensively tested in Japan, North America, South America, Europe, and South Africa. Anodes have been service for up to 5 years without significant thinning or corrosion. The anodes remain straight and MnO2 removal is easier than with cast or rolled lead silver anodes. The anodes yield a 1% improvement in current efficiency when compared to conventional anodes. This paper describes the experiences with rolled lead-calcium-silver anodes, the resistance or inertia to their use, the manufacturing process, and improvements to surface treatment and handling which will enhance the use of the anodes in cellhouse operations. The paper also compares the significant economic benefits in utilizing RSR rolled lead-calcium-silver anodes in today's environment.


Ellis T.W.,Dallas Technologies | Mirza A.H.,Dallas Technologies
Journal of Power Sources | Year: 2010

Secondary lead, i.e. material produced by the recycling of lead-acid batteries has become the primary source of lead in much of the world. This has been important to the secondary lead industry as other uses have dwindled, e.g. lead based pigments, chemicals, fuel additives, solders and CRT glasses [1]. Presently, battery manufacturing accounts for greater than 80% of lead consumption while recycled lead accounts for approximately the same market share of lead supply. These two facts strongly demonstrate the battery manufacturing and recycled lead are intimately coupled in everyday life. In this paper we will explore how recycled lead has become the material of choice for battery construction through the development of a recovery and refining process that exceeds the industries requirements. Particular focus will be on addressing the results presented by Prengaman [2] on the effects of contaminant or tramp elements on gassing in lead-acid batteries. © 2010 Elsevier B.V. All rights reserved.


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