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Pocheon, South Korea

Daejin University is a private university in Pocheon City, Gyeonggi province of South Korea. About 200 instructors are employed. The current president is Chung, Tae Soo, who has served since the university's founding.The university operates Daejin University China Campus, a study abroad program based at the campuses of two universities in the People's Republic of China: Soochow University in Suzhou, and Harbin Normal University in Harbin. Wikipedia.

An effective method for the 3D porous scaffold design of human tissue is presented based on a hybrid method of distance field and triply periodic minimal surface (TPMS). By the creative application of traditional distance field algorithm into the Boolean operations of the anatomical model and TPMS-based unit cell library, an almost defects free porous scaffolds having the complicated micro-structure and high quality external surface faithful to a specific anatomic model can be easily obtained without the difficult and time-consuming trimming and re-meshing processes. After generating the distance fields for the given tissue model and required internal micro-structure, a series of simple modifications in distance fields enable us to obtain a complex porous scaffold. Experimental results show that the proposed scaffold design method has the potential to combine the perfectly interconnected pore networks based on the TPMS unit cell libraries and the given external geometry in a consistent framework irrespective of the complexity of the models. © 2011 Elsevier Ltd. Source

Yoo D.,Daejin University
Materials Science and Engineering C | Year: 2013

This paper presented an effective method for the three-dimensional (3D) hierarchical porous scaffold design for tissue engineering. To achieve such a hierarchical porous structure with accurately controlled internal pore architectures, the recursive intersection Boolean operation (RIBO) was proposed in order to satisfy computational efficiency and biological function requirements of a porous scaffold. After generating the distance field (DF) for the given anatomic model and required pore architectures, the recursive DF modifications enable us to design hierarchical porous scaffolds with complex combinations of pore morphologies. A variety of experimental results showed that the proposed hierarchical porous scaffold design method has the potential benefits for accurately controlling both the porosity and the pore architecture gradients while preserving the advantages of triply periodic minimal surface pore geometries. © 2013 Elsevier B.V. All Rights Reserved. Source

Yoo D.-J.,Daejin University
International Journal of Precision Engineering and Manufacturing | Year: 2012

Recently, a paradigm shift is taking place in tissue engineering scaffold design from homogeneous porous scaffolds to functionally graded scaffolds that have heterogeneous internal structures with controlled porosity levels and architectures. This paper presents a new heterogeneous modeling methodology for designing tissue engineering scaffolds with precisely controlled porosity and internal architectures using triply periodic minimal surfaces. The internal architectures and porosity at the spatial locations of the scaffolds are determined based on a given distribution of architectures and porosity levels specified at a few selected points on the model. After generating the hexahedral elements for a 3D anatomical shape using the distance field algorithm, the unit cell libraries composed of triply periodic minimal surfaces are mapped into the subdivided hexahedral elements using the shape function widely used in the finite element method. By simply allocating parameter values related to the porosity and architecture type to the corner nodes in each hexahedral element, we can easily and precisely control the pore size, porosity, and architecture type at each region of the scaffold while preserving perfectly interconnected pore networks across the entire scaffold. © KSPE and Springer 2012. Source

Advanced additive manufacture (AM) techniques are now being developed to fabricate scaffolds with controlled internal pore architectures in the field of tissue engineering. In general, these techniques use a hybrid method which combines computer-aided design (CAD) with computer-aided manufacturing (CAM) tools to design and fabricate complicated three-dimensional (3D) scaffold models. The mathematical descriptions of micro-architectures along with the macro-structures of the 3D scaffold models are limited by current CAD technologies as well as by the difficulty of transferring the designed digital models to standard formats for fabrication. To overcome these difficulties, we have developed an efficient internal pore architecture design system based on triply periodic minimal surface (TPMS) unit cell libraries and associated computational methods to assemble TPMS unit cells into an entire scaffold model. In addition, we have developed a process planning technique based on TPMS internal architecture pattern of unit cells to generate tool paths for freeform fabrication of tissue engineering porous scaffolds. © 2012 IPEM. Source

Yoo D.-J.,Daejin University
CAD Computer Aided Design | Year: 2011

An effective method for the 3D Bio-CAD model reconstruction of human bone from a scanned point cloud data or a sequence of CT image data is presented based on a B-spline interpolation scheme. In the method, a base surface is generated by creating a smooth implicit surface from the given point cloud data or a sequence of CT image data. The implicit surface is defined by a combination of the well-known thin plate radial basis functions (RBFs) using the domain decomposition method (DDM). After generating the base implicit surface, various types of CAD models such as surface and solid are constructed by using the base implicit surface. In order to reconstruct a complex model, voxel data which can be extracted easily from the base implicit surface are used to generate a rectangular curve net with good quality using the projection and smoothing scheme. After generating the interior points and tangential vectors in each rectangular region considering the required accuracy, a complex B-spline surface is reconstructed by interpolating the rectangular array of points. Experimental results show that the proposed method creates the three dimensional shapes of human bones suitable for bone scaffold design, finite element analysis, and medical diagnosis. © 2011 Elsevier Ltd. All rights reserved. Source

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