Selden P.A.,University of Kansas |
Selden P.A.,Natural History Museum in London |
Nam K.-S.,Daejeon Science High School |
Kim S.H.,University of Wisconsin - Madison |
Kim H.J.,Chonnam National University
Journal of Paleontology | Year: 2012
A fossil spider from the Cretaceous Jinju Formation of Korea is redescribed as Korearachne jinju, n. gen. n. sp. Previous description of this specimen, the only known fossil spider from Korea, was inadequate, and here we present a more detailed interpretation and illustration of the specimen. The fossil spider is preserved alongside juvenile albuiform fish, Diptera and possible crustaceans, which suggests a mass mortality event. Familial identification of the spider is impossible, but it probably belongs to a guild of wandering spiders, possibly lycosoids. © 2012 The Paleontological Society.
Lim H.Y.,Chungnam National University |
Ju H.Y.,Daejeon Science High School |
Chung H.-Y.,Hanyang University |
Kim Y.S.,Chungnam National University
Cancer Biology and Therapy | Year: 2010
We investigated whether expression of the IL-12 p35 subunit in membrane-bound form in tumor cells enhanced their immunogenicity. Since p35 is only secreted when associated with the IL-12 p40 subunit, we generated tumor cells expressing membrane-bound forms of p35 and p40 as chimeras with the transmembrane/cytoplasmic region of TNFα (mbIL-12p35 and mbIL-12p40). The relevant vectors were transfected into MethA fibrosarcoma cells, and mbIL-12p35 or mbIL-12p40-expressing tumor clones were isolated and their ability to induce anti-tumor immunity studied. Cells of the mbIL-12p35 tumor clone induced CD69 expression and IFNγ production in purified CD8+ T cells in vitro, and their in vivo tumorigenicity was reduced. Cells of the mbIL-12p40 tumor clone failed to show either of these activities. Mice that had rejected cells of the mbIL-12p35 tumor clone possessed systemic anti-tumor immunity to wild type tumor cells. The growth rate of mbIL-12p35 tumor cells was greater in CD8+ T cell-depleted mice than in CD4+ T cell- and NK cell-depleted mice or normal mice, suggesting that CD8+ T cells were mainly responsible for the anti-tumor immunity. These results indicate that expression of mbIL-12p35 on tumor cells enhances their immunogenicity by increasing their ability to activate CD8+ T cells, possibly by direct priming. © 2010 Landes Bioscience.
Kang J.-H.,National Research Institute of Cultural Heritage |
Lee Y.-J.,National Research Institute of Cultural Heritage |
Oh B.-K.,National Research Institute of Cultural Heritage |
Lee S.-K.,National Research Institute of Cultural Heritage |
And 4 more authors.
Journal of Asia-Pacific Biodiversity | Year: 2014
This study is aimed to identify the external features of the water spiders (Argyroneta aquatica) collected from "The Natural Monument No. 412 Yeoncheon Eundaeri Water Spider Habitat" through observation of their microstructures using a scanning electron microscope. There is no study on the microstructures of the water spiders excluding several studies on protection plans and ecological investigations, thus giving this study considerable academic significance. Based on the scanning electron microscopy analysis, the water spider has eight simple eyes, and both of its lateral simple eyes are stuck together. A lateral bump was confirmed on the upper jaw, and the pedipalps had six joints and the legs had seven joints. The abdomen and sternum of A. aquatica have more hairs compared with those of land spiders, and its structure shows an elongated area of contact with the air bell so that the air bell can become attached to the abdomen better. Copyright © 2014 National Science Museum of Korea (NSMK) and Korea National Arboretum (KNA).
Rho H.,Daejeon Science High School |
Shin B.,Chungnam National University |
Lee O.,Chungnam National University |
Choi Y.-H.,Chungnam National University |
And 2 more authors.
Journal of Environmental Monitoring | Year: 2012
The increasing usage of antibiotics in the animal farming industry is an emerging worldwide problem contributing to the development of antibiotic resistance. The purpose of this work was to investigate the prevalence and antibiotic resistance profile of bacterial isolates collected from animal farming aquatic environments and meats in a peri-urban community in Daejeon, Korea. In an antibacterial susceptibility test, the bacterial isolates showed a high incidence of resistance (∼26.04%) to cefazolin, tetracycline, gentamycin, norfloxacin, erythromycin and vancomycin. The results from a test for multiple antibiotic resistance indicated that the isolates were displaying an approximately 5-fold increase in the incidence of multiple antibiotic resistance to combinations of two different antibiotics compared to combinations of three or more antibiotics. Most of the isolates showed multi-antibiotic resistance, and the resistance patterns were similar among the sampling groups. Sequencing data analysis of 16S rRNA showed that most of the resistant isolates appeared to be dominated by the classes Betaproteobacteria and Gammaproteobacteria, including the genera Delftia, Burkholderia, Escherichia, Enterobacter, Acinetobacter, Shigella and Pseudomonas. © 2012 The Royal Society of Chemistry.