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Adana, Turkey

Çukurova University has sixteen faculties, three colleges, seven vocational colleges, three institutes and twenty six research and application centers. The university campus is located 10 kilometers away from Adana city center, by the Seyhan Dam Lake.The university, with its 1903 teaching staff, offers courses to over 40,000 undergraduate, post graduate and doctorate students.The library has internet access and houses national and international publications. Computer rooms are available for student use campus-wide. These computer rooms are also used for computer-assisted education and scientific research. The university also offers its students recreational facilities including an indoor sports center and swimming pool, a boathouse and sports grounds. Students can make the best of their leisure time in any of the 29 student clubs.The students of the university have the opportunity to do practical training abroad through AIESEC and similar organizations. Transportation to the Balcalı Campus is offered by private bus services. Wikipedia.

Paydas S.,Cukurova University
Critical Reviews in Oncology/Hematology | Year: 2014

Dasatinib is a second generation tyrosine kinase inhibitor approved for clinical use in first line and imatinib-resistant chronic myeloid leukemia and Philadelphia positive (Ph+) acute lymphoblastic leukemia. In addition to BCR-ABL1, dasatinib inhibits TEC kinases and SRC family kinases and is more potent than imatinib in the treatment of Ph+ leukemias. In the last 3 years, increases in cytotoxic T and natural-killer cells in peripheral blood samples have been reported in cases treated by dasatinib. The awareness of the clonal expansion of large granular lymphocytes and beneficial effect of these clonal cells increased the interest to dasatinib in cases receiving this drug. Clonal expansion of large granular lymphocytes is an important effect of dasatinib therapy, shown to be an off-target phenomenon associated with pleural effusion and better clinical response. The benefit of dasatinib-induced lymphocytosis and its underlying mechanism of this are important points for clinicians working in hematology and oncology. © 2013 Elsevier Ireland Ltd. Source

Paydas S.,Cukurova University
Critical Reviews in Oncology/Hematology | Year: 2015

Hepatitis C virus (HCV) is a hepatotrophic and lymphotrophic virus and is a global health problem. Cirrhosis and hepatocellular cancer are the most common complications of HCV. Association between HCV and B cell non-Hodgkin lymphomas (B-NHL) has been shown in epidemiological studies in the last 20 years. High prevalence of HCV infection among patients with NHL has been reported in the early 1990s by Ferri in Italy and this association has been confirmed in later studies. Geographically, HCV related NHL is highly variable and chronic rather than cleared HCV infection is required for lymphomagenesis. Although anti-HCV antibody test is the most commonly used technique in epidemiological studies, HCV-RNA is more useful test to detect the association between HCV and NHL. The optimal management of HCV related NHL is not clear. However, anti-viral treatment may be sufficient for cases with low grade and/or asymptomatic lymphomas, while immuno-chemotherapy is necessary, in spite of probable hepatic toxicity, in cases with high grade lymphomas. © 2014 Elsevier Ireland Ltd. Source

Tumgor G.,Cukurova University
World Journal of Gastroenterology | Year: 2014

Hepatopulmonary syndrome (HPS) is characterized as a triad: liver disease, intrapulmonary vascular dilatation and arterial hypoxemia. HPS is reported to be present in 4% to 32% of adult patients with end-stage liver disease and in 9%-20% of children. The pathogenesis of HPS has not been clearly identified. Portal hypertension causes impairment in the perfusion of the bowel and increases the enteral translocation of Gram (-) bacteria and endotoxins. This stimulates the release of vasoactive mediators, such as tumor necrosis factor-alpha, heme oxygenase-derived carbon monoxide and nitric oxide. Genetic alterations have not been associated with this syndrome yet; however, cytokines and chemokines have been suggested to play a role. Recently, it was reported that cumulated monocytes lead to the activation of vascular endothelial growth factor-dependent signaling pathways and pulmonary angiogenesis, which plays an important role in HPS pathogenesis. At present, the most effective and only radical treatment is a liver transplant (LT). Cirrhotic patients who are on the waiting list for an LT have a shorter survival period if they develop HPS. Therefore, it is suggested that all cirrhotic cases should be followed closely for HPS and they should have priority in the waiting list. © 2014 Baishideng Publishing Group Co., Limited. All rights reserved. Source

The main purpose of this study is to design a "Courseware Development Model" (CDM) and investigate its effects on pre-service teachers' academic achievements in the field of geography and attitudes toward computer-based education (ATCBE). The CDM consisted of three components: content (C), learning theory, namely, meaningful learning (ML).; multimedia (M). The CDM is designed to show the synthesis of the C and M components under ML. In this study, an experimental design including pre-test and post-test groups is used to define the efficiency of the CDM. There are 31 pre-service teachers in the control group, 28 pre-service teachers in the meaningful learning theory group-ML.; 30 pre-service teachers in GTC group that uses geography teaching courseware-GTC based on the CDM. The results of the analysis indicate that the courseware is quite effective, improving pre-service teachers' academic achievements as well as their ATCBE scores. The results also suggest that the new model has an appropriate structure for courseware design. © 2012 Elsevier Ltd. All rights reserved. Source

The potential effect of indigenous and selected mycorrhizal fungal inoculation and phosphorus (P) treatment on plant growth, yield, root infection and inoculation effectiveness (IE) were tested with and without methyl bromide (MBr) for three successive years under field conditions. In 1997-1999, twelve plant species were used as host plants in a Menzilat soil series (Typic Xerofluvents) in the Mediterranean coastal region of Turkey. Compared to non-inoculated control plants, mycorrhizal inoculation increased yield in some years, but not in others. The mycorrhizal inoculum increased the root colonization of garlic, horsebean, soybean, chickpea, melon, watermelon, cucumber, maize, cotton, pepper, eggplant and tomato plants compared with the non-inoculated treatments. Compared to fumigation, plant roots grown in non-fumigated soil and successfully infected by indigenous mycorrhiza, resulted with better plant growth. Plant species belonging to the Solanaceae, Leguminosae, and Cucurbitaceae showed high responses to the mycorrhizal inoculation effectiveness under both fumigated and non-fumigated soil conditions. In general, IE was higher under low P supply than under high P supply. The effects of mycorrhizal inoculation on plant P and Zn concentrations were determined: mycorrhiza-inoculated plants had a higher nutrient content than non-inoculated plants, and this was most pronounced under fumigated soil conditions. After 3 years of field experiments, it has been concluded that for (seeded) field crops, soil and plant management systems make a great contribution to indigenous mycorrhiza to improve plant development. Whereas for horticultural plants, on the other hand, (plants transplanted into the field as seedlings), mycorrhizal inoculation makes it easy to use for large agricultural areas compared with the non-inoculated plants. It can be suggested to the farmers that arbuscular mycorrhizal fungus inoculated seedlings can be used under field conditions for high yield and quality. © 2011 Elsevier B.V. Source

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