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News Article | April 17, 2017
Site: www.newscientist.com

A form of life that uses a fresh genetic “language” could be just a few years away. This comes after geneticists used a new technique to recode 5 per cent of the Salmonella bacterium’s genome, introducing a record number of engineered changes into a single organism. Now the race is on to recode the entire genome and put the microbes to work. Genome recoding is seen by many as the next big thing in genetic engineering. Among other things, it offers geneticists a way to engineer the proteins produced by organisms and give them new properties – allowing the creation of proteins that don’t exist in nature, and potential uses in new types of drugs and vaccines. Standard proteins are built from 20 amino acids, which are in turn coded for by “codons” – runs of three DNA “letters” in the genetic code (TTT, TTC, and so on). It’s possible to produce 64 distinct codons, meaning there is a lot of redundancy in the system because amino acids are usually coded for by more than one codon. The amino acid leucine, for example, is produced by six different codons. That redundancy could be used to our advantage. For instance, if an entire genome was recoded so that leucine was produced by just one codon, it would free up five others that could be reassigned to produce brand new amino acids beyond the 20 natural ones, potentially leading to new commercially useful proteins. The novel amino acids are important for another reason: they are fundamentally alien to life on Earth. An organism with a fully recoded genome would, in effect, use a subtly different genetic “language” to everything else on the planet. Its DNA would be unable to function properly in other organisms, because they would be unable to read it. This is a particularly useful trait in the microbial realm, in which cells are only too willing to “talk” to one another and share genetic information. That process of DNA sharing is a problem for researchers who want to use genetically engineered bacteria in real-world applications, because society demands that any genetically modified organism doesn’t transfer those modifications to other organisms in the environment. “Ideally, you would have a firewall between your bacterium and the other bacteria,” says Jeffrey Way at Harvard University’s Wyss Institute. Recoding the genome provides that firewall because the new code would be meaningless to natural life forms. It’s a mammoth task to recode one or more codons across an entire genome. However, a team led by Way and his colleague Yu Heng Lau – both members of Pamela Silver’s laboratory at the Wyss Institute – thinks it might be no more than a few years away from achieving the feat. Working with a strain of Salmonella, the team has already made more than 1550 codon changes in 176 genes. The researchers decided to free up two codons that code for leucine, TTA and TTG, by replacing them with CTA and CTG codons, which also code for leucine. They designed the new Salmonella DNA on a computer and paid a commercial supplier to build it. Such suppliers typically provide DNA in short strands, 1-4 kilobases long. To build longer stretches, the geneticists inserted the DNA fragments into yeast cells, which can naturally assemble them into strands 20 kb long. Then came the crucial step – one that the team thinks might be key to making genome recoding much quicker. The researchers used a new technique to replicate each modified 20-kb DNA strand inside the yeast and produce large quantities at the level of micrograms. Then they inserted modified DNA into the Salmonella. The hope was that the bacteria would then do some of the geneticists’ work for them. When bacterial cells divide and replicate their DNA, they may incorporate a new strand of DNA if it happens to be present in the cell. What’s more, if that new strand of DNA has a near-identical sequence to a particular region of the bacterial genome, some of the bacteria should even incorporate the new DNA in that region. This process is known as recombineering, which is a form of “crossing over” between similar DNA strands that occurs naturally in all organisms. Geneticists have used recombineering to insert new DNA sequences in the past, but those were typically only about 3-4 kb rather than 20 kb long. “We were initially unsure if this was feasible,” says Lau. “But it actually worked well enough for our purposes.” It took roughly two days to insert a particular 20 kb section. After that, the team could give the Salmonella engineered DNA corresponding to the next 20 kb of the genome’s DNA sequence and wait for the bacteria to incorporate it, and so on. The approach offers an efficient way to design and assemble recoded genomes, says Marc Lajoie at the University of Washington in Seattle, a member of a team using a different method to recode E. coli. “I think their method will provide a complementary tool for existing efforts to synthesise radically recoded organisms,” he says. Way says it might be no more than a couple of years before the team has applied the technique across the entire Salmonella genome, which will involve changing more than 33,000 codons in total. At that point, the microbe could find uses in vaccine development, he says. Many bacterial vaccines are made using dead microbes because of the risk that living ones would swap genetic material with others in the human body. Because recoded bacteria would be unable to communicate with other microbes, it should be possible to use them to create “live” vaccines – which can be far more effective. “That’s an example of a real-world use of this technology,” says Way. “Salmonella would be a perfect bacterium to work with.” Read more: Synthetic supermicrobe will be resistant to all known viruses; Reprogrammed bacterium speaks new language of life


News Article | April 24, 2017
Site: www.businesswire.com

ARLINGTON, Virginie--(BUSINESS WIRE)--La Consumer Technology Association (CTA) a annoncé aujourd'hui que M. Wan Biao, chef d'exploitation chez Huawei Consumer BG, fera une allocution lors du CES Asia™ 2017, qui se déroulera du 7 au 9 juin à Shanghai, Chine. Le discours liminaire est prévu pour le matin du mercredi 7 juin, au Kerry Hotel, Shanghai Ballroom 2-3. Gary Shapiro, président et CEO de la CTA prononcera, avant l'allocution de M. Wan, le discours d'ouverture abordant la situation général


News Article | April 26, 2017
Site: www.businesswire.com

米バージニア州アーリントン--(BUSINESS WIRE)--(ビジネスワイヤ) -- 全米民生技術協会(CTA)は本日、ファーウェイ(華為技術)消費者業務集団の万飈首席運営官(COO)が、6月7~9日に中国・上海で開催される2017年CESアジアでオープニング基調講演を行うと発表しました。オープニング基調講演は、6月7日(水)午前にケリーホテルの上海ボールルーム2-3で実施されます。CTAのゲーリー・シャピロ社長兼最高経営責任者(CEO)は、万氏の基調講演に先立って開会の挨拶を行い、世界の技術業界の全体的な状況について触れます。 CESアジアは、消費者向け技術の未来に関する貴重な知見、企業の画期的成果、大きなアイデアを共有するプラットフォームを業界のリーダー、ビジョナリー、幹部に提供しています。ファーウェイは、完全に接続された世界の構築に取り組む世界的ブランドです。万氏の基調講演では、より良い知的端末エコシステムの構築方法に関するファーウェイの戦略的ビジョンと業界見通しを紹介します。 CTAのゲーリー・シャピロ社長兼最高経営責任者(CEO)は、次のように述べています。「世界有数の


ARLINGTON, Va.--(BUSINESS WIRE)--De Consumer Technology Association (CTA) heeft vandaag bekendgemaakt dat de heer Wan Biao, operationeel bestuurder van Huawei Consumer BG, de keynotespeech geeft op CES Asia™ 2017, dat van 7 tot 9 juni plaatsvindt in Shanghai, China. De openingsspeech staat in de ochtend van woensdag 7 juni gepland in de Shanghai Ballroom 2-3 van het Kerry Hotel. Gary Shapiro, president en ceo van CTA, houdt voorafgaand aan Wans keynote een openingstoespraak over de algehele staat van de mondiale technologische sector. Deze bekendmaking is officieel geldend in de originele brontaal. Vertalingen zijn slechts als leeshulp bedoeld en moeten worden vergeleken met de tekst in de brontaal, die als enige rechtsgeldig is.


News Article | April 19, 2017
Site: www.PR.com

Art Education a Necessity, Not an Extra at Shorecrest Known as “Celebrate the Arts,” the 2017 weeklong series of events runs from April 17-22 and features a teach-in with more than two dozen local artists, music and theatre performances, student artwork displayed throughout the school and juried in Middle and Upper School, and a campus exhibition of work by internationally recognized printmaker and graphic artist Barry Goodman. The week culminates with the Shorecrest spring musical production, “Les Misérables” with performances on April 20-22. St. Petersburg, FL, April 19, 2017 --( The arts are such a critical component to the Shorecrest curriculum that for nearly 30 years, the school has dedicated an entire week each spring to their study across the pre-k through 12th grade St. Petersburg school. Known as “Celebrate the Arts,” the 2017 weeklong series of events runs from April 17-22 and features a teach-in with more than two dozen local artists, music and theatre performances, student artwork displayed throughout the school and juried in Middle and Upper School, and a campus exhibition of work by internationally recognized printmaker and graphic artist Barry Goodman. The week culminates with the Shorecrest spring musical production, “Les Misérables” with performances on April 20, 21, and 22. Mr. Murphy continues, “Like academic excellence and physical well-being, creative achievement is a core part of our mission at Shorecrest. Celebrate the Arts week is a tradition that allows students, teachers, and parents to come together with each other and with artists in our community to honor all of the ways the arts impact us.” Celebrate the Arts at Shorecrest begins on Monday, April 17, with events through Saturday, April 22. For a full list of events, performance times and featured artists, please visit www.shorecrest.org/CTA. About Shorecrest: Founded in 1923, Shorecrest is a coed, nonsectarian, PK-12 independent school in St. Petersburg, FL. In a safe, student-centered environment, Shorecrest educates a diverse community of students to become lifelong learners in the pursuit of personal and academic excellence, physical well-being, creative achievement and the development of a commitment to social responsibility. Shorecrest graduates empathetic, independent thinkers who succeed at the university level, pursue their passions, and lead purposeful lives. Learn more at www.shorecrest.org. St. Petersburg, FL, April 19, 2017 --( PR.com )-- Preschool students work in an outdoor classroom, modeling paintings after the work of Monet. Kindergartners sew thoughtfully designed quilts alongside their parents and friends. Eighth graders create ROV prototypes out of PVC. High schoolers paint a mural at a community garden during Service Week. These and similar scenes are the norm at Shorecrest Preparatory School, where the arts are inseparable from other subject areas. “With our commitment to project-based learning, there are elements of art in almost everything our students do,” says Shorecrest Headmaster Mike Murphy.The arts are such a critical component to the Shorecrest curriculum that for nearly 30 years, the school has dedicated an entire week each spring to their study across the pre-k through 12th grade St. Petersburg school. Known as “Celebrate the Arts,” the 2017 weeklong series of events runs from April 17-22 and features a teach-in with more than two dozen local artists, music and theatre performances, student artwork displayed throughout the school and juried in Middle and Upper School, and a campus exhibition of work by internationally recognized printmaker and graphic artist Barry Goodman. The week culminates with the Shorecrest spring musical production, “Les Misérables” with performances on April 20, 21, and 22.Mr. Murphy continues, “Like academic excellence and physical well-being, creative achievement is a core part of our mission at Shorecrest. Celebrate the Arts week is a tradition that allows students, teachers, and parents to come together with each other and with artists in our community to honor all of the ways the arts impact us.”Celebrate the Arts at Shorecrest begins on Monday, April 17, with events through Saturday, April 22. For a full list of events, performance times and featured artists, please visit www.shorecrest.org/CTA.About Shorecrest:Founded in 1923, Shorecrest is a coed, nonsectarian, PK-12 independent school in St. Petersburg, FL. In a safe, student-centered environment, Shorecrest educates a diverse community of students to become lifelong learners in the pursuit of personal and academic excellence, physical well-being, creative achievement and the development of a commitment to social responsibility. Shorecrest graduates empathetic, independent thinkers who succeed at the university level, pursue their passions, and lead purposeful lives. Learn more at www.shorecrest.org. Click here to view the list of recent Press Releases from Shorecrest Preparatory School


News Article | April 17, 2017
Site: www.prweb.com

The Northern Virginia Technology Council (NVTC) will host the third annual NVTC CXO Auction on April 20, 2017. During the event, regional and industry C-level executives will be auctioned off to raise money for NVTC's Veterans Employment Initiative, which provides tools and resources to match Veterans with employment opportunities in Virginia's technology community. At the live auction event, attendees will bid electronically to win one-on-one meetings with C-level leaders. Participating CXOs are looking to meet qualified vendors for future projects. Winning bidders are guaranteed a meeting with their auctioned executive within 12 months, during which they can gain insight, pitch future plans or receive advice. Some auction packages go beyond a meeting to include a lunch, dinner, wine tastings and rounds of golf. Brad Antle, CEO, and Tom Ferrando, President, SalientCRGT Kenneth Asbury, President and CEO, CACI International John Backus, Co-Founder and Managing Partner, NAV.VC Mike Baird, CEO, Avizia Rodney Blevins, Senior Vice President and CIO, Dominion Resources, Inc Teresa Carlson, Vice President Worldwide Public Sector, Amazon Web Services Kelly Clark, CIO, MAXIMUS Marilyn Crouther, Senior Vice President and General Manager, Hewlett Packard Enterprise Mac Curtis, President and CEO, Vencore Karen Dahut, Executive Vice President, Booz Allen Hamilton Ted Davies, President and CEO, Altamira Technologies Corporation Nelson Ford, President and CEO, LMI Mark Frantz, Co-Founder, Blue Delta Capital Partners Kim Hayes, CEO and Co-Founder, The Ambit Group Timothy Hurlebaus, President, CGI Federal Sudhakar Kesavan, Chairman and CEO, ICF Curt Kolcun, Vice President, U.S. Public Sector, Microsoft Paul Leslie, CEO, Dovel Technologies Joe Martore, President and CEO, CALIBRE Systems Terri McClements, Market Managing Partner, and Mohamed Kande, Vice Chairman and U.S. Advisory Leader, PwC Rich Montoni, CEO, MAXIMUS Tony Moraco, CEO, SAIC Dan O'Neill, President and CEO, SunTrust, Inc. Carolyn Parent, President and CEO, LiveSafe Shailesh Prakash, Chief Product and Technology Officer, The Washington Post Larry Prior, President and CEO, CSRA Dr. Jason Providakes, President and CEO, MITRE Brian Roach, Executive Vice President and Managing Director Regulated Industries, SAP North America James Schenck, President and CEO, PenFed Credit Union Gary Shapiro, President and CEO, and Karen Chupka, Senior Vice President CES and Corporate Business Strategy, CTA Todd Stottlemyer, CEO, Inova Center for Personalized Health Matthew Strottman, COO, In-Q-Tel John Wood, Chairman and CEO, Telos Corporation Auction packages include meetings and excursions such as an Italian dinner with SAIC CEO Tony Moraco; a VIP CES 2018 ticket package and a meal with CTA President and CEO Gary Shapiro and CTA Senior Vice President CES and Corporate Business Strategy Karen Chupka; a Topgolf outing with Altamira Technologies Corporation President and CEO Ted Davies and Altamira principals; a dinner and wine tasting with CACI President and CEO Kenneth Asbury and select CACI leaders, as well as many more opportunities! In a new bonus auction, NVTC will also be auctioning off four tickets to see Hamilton during its 2018 run at the Kennedy Center. REGISTRATION:     To register as a member of the press, please contact Alexa Magdalenski at 703-904-7878, ext. 207 or email amagdalenski(at)nvtc(dot)org. The event is free for press, but advanced registration is required. Press credentials are required for entry. The Northern Virginia Technology Council (NVTC) is the membership and trade association for the technology community in Northern Virginia. As the largest technology council in the nation, NVTC serves about 1,000 companies from all sectors of the technology industry, as well as service providers, universities, foreign embassies, nonprofit organizations and governmental agencies. Through its member companies, NVTC represents about 300,000 employees in the region. NVTC is recognized as the nation's leader in providing its technology community with networking and educational events; specialized services and benefits; public policy advocacy; branding of its region as a major global technology center; initiatives in targeted business sectors and in the international, entrepreneurship, workforce and education arenas; and the NVTC Foundation, a 501(c)(3) nonprofit charity that supports the NVTC Veterans Employment Initiative and other priorities within Virginia's technology community. Visit NVTC at http://www.nvtc.org.


News Article | May 3, 2017
Site: marketersmedia.com

Summary Nicotine addiction also called tobacco dependence is an addiction to tobacco products caused by the drug nicotine. Predisposing factors include age, depression, schizophrenia, post-traumatic stress disorder and alcoholism. Person experiences withdrawal symptoms at cessation of using, such as shaky hands, sweating, irritability, or rapid heart rate. Treatment includes nicotine replacement therapy (NRT). Report Highlights Pharmaceutical and Healthcare latest pipeline guide Nicotine Addiction – Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Nicotine Addiction (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. The Nicotine Addiction (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Nicotine Addiction and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase II, IND/CTA Filed, Preclinical and Discovery stages are 1, 1, 11 and 1 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 5 molecules, respectively. Nicotine Addiction (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis. Scope - The pipeline guide provides a snapshot of the global therapeutic landscape of Nicotine Addiction (Central Nervous System). - The pipeline guide reviews pipeline therapeutics for Nicotine Addiction (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources. - The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages. - The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities. - The pipeline guide reviews key companies involved in Nicotine Addiction (Central Nervous System) therapeutics and enlists all their major and minor projects. - The pipeline guide evaluates Nicotine Addiction (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. - The pipeline guide encapsulates all the dormant and discontinued pipeline projects. - The pipeline guide reviews latest news related to pipeline therapeutics for Nicotine Addiction (Central Nervous System) Reasons to buy - Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies. - Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage. - Find and recognize significant and varied types of therapeutics under development for Nicotine Addiction (Central Nervous System). - Classify potential new clients or partners in the target demographic. - Develop tactical initiatives by understanding the focus areas of leading companies. - Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics. - Formulate corrective measures for pipeline projects by understanding Nicotine Addiction (Central Nervous System) pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline. Table of Content: Key Points List of Tables List of Figures Introduction Nicotine Addiction - Overview Nicotine Addiction - Therapeutics Development Pipeline Overview Pipeline by Companies Pipeline by Universities/Institutes Products under Development by Companies Products under Development by Universities/Institutes Nicotine Addiction - Therapeutics Assessment Assessment by Target Assessment by Mechanism of Action Assessment by Route of Administration Assessment by Molecule Type Nicotine Addiction - Companies Involved in Therapeutics Development Addex Therapeutics Ltd Astraea Therapeutics LLC C4X Discovery Holdings PLC Chronos Therapeutics Ltd CV Sciences Inc Hager Biosciences LLC Heptares Therapeutics Ltd …Continued For more information, please visit http://www.wiseguyreports.com


News Article | April 25, 2017
Site: www.businesswire.com

ARLINGTON, Va.--(BUSINESS WIRE)--La Consumer Technology Association (CTA) oggi ha annunciato che Wan Biao, Direttore finanziario (COO) di Huawei Consumer BG, terrà l’intervento di apertura al CES Asia™ 2017, che si svolgerà dal 7 al 9 giugno a Shanghai, Cina. L’intervento di apertura è programmato per la mattina di mercoledì 7 giugno al Kerry Hotel, Shanghai Ballroom 2-3. Gary Shapiro, Presidente e Amministratore delegato CTA, precederà Wan sul podio con un intervento che illustrerà lo stato co


News Article | April 25, 2017
Site: www.businesswire.com

ARLINGTON, Va.--(BUSINESS WIRE)--A Consumer Technology Association (CTA) anunciou hoje que o Sr. Wan Biao, Diretor de Operações da Huawei Consumer BG, fará o discurso de abertura na CES Asia™ 2017, que ocorre de 7 a 9 de junho em Xangai, China. O discurso de abertura está agendado para a manhã de quarta-feira, 7 de junho, no Kerry Hotel, Xangai no salão de festas 2-3. Gary Shapiro, Presidente e Diretor Executivo da CTA, irá anteceder ao discurso do Sr. Wan com um tema de abertura que irá aborda


News Article | April 25, 2017
Site: www.businesswire.com

ARLINGTON, Virginia--(BUSINESS WIRE)--Die Consumer Technology Association (CTA) gab heute bekannt, dass Wan Biao, Chief Operating Officer von Huawei Consumer BG, die programmatische Eröffnungsrede auf der CES Asia™ 2017 halten wird. Die Messe findet vom 7. bis 9. Juni in Shanghai, China, statt. Die Eröffnungs-Keynote steht für Mittwoch, den 7. Juni morgens im Kerry Hotel, Shanghai, Ballroom 2-3, auf dem Programm. Gary Shapiro, President und CEO, CTA, hält vor der Keynote von Wan eine Eröffnungs

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