CSIC - Institute of Refrigeration

Madrid, Spain

CSIC - Institute of Refrigeration

Madrid, Spain

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Patent
CSIC - Institute of Refrigeration and Polytechnic University of Valencia | Date: 2016-12-22

The invention relates to a catalytic activation layer for use in oxygen-permeable membranes, which can comprise at least one porous structure formed by interconnected ceramic oxide particles that conduct oxygen ions and electronic carriers, where the surface of said particles that is exposed to the pores is covered with nanoparticles made from a catalyst, the composition of which corresponds to the following formula: A_(1-x-y)B_(x)C_(y)O_(R )where: A can be selected from Ti, Zr, Hf, lanthanide metals and combinations thereof; B and C are metals selected from Al, Ga, Y, Se, B, Nb, Ta, V, Mo, W, Re, Mn, Sn, Pr, Sm, Tb, Yb, Lu and combinations of same; and A must always be different from B. 0.01


Patent
CSIC - Institute of Refrigeration | Date: 2017-05-10

The invention relates to a catalytic activation layer for use in oxygen-permeable membranes, which can comprise at least one porous structure formed by interconnected ceramic oxide particles that conduct oxygen ions and electronic carriers, where the surface of said particles that is exposed to the pores is covered with nanoparticles made from a catalyst, the composition of which corresponds to the following formula: A_(1-x-y)B_(x)C_(y)O_(R) where: A can be selected from Ti, Zr, Hf, lanthanide metals and combinations thereof; B and C are metals selected from Al, Ga, Y, Se, B, Nb, Ta, V, Mo, W, Re, Mn, Sn, Pr, Sm, Tb, Yb, Lu and combinations of same; and A must always be different from B. 0.01 < x < 0.5; 0 < y < 0.3.


Patent
CSIC - Institute of Refrigeration | Date: 2017-05-17

The present document provides details of a nanostructured material defined by an anodized alumina having a nanostructure with transverse pores that pass through and connect longitudinal pores grown on an aluminium substrate. This document also describes the process for producing said nanostructured material and the possible use thereof as a template or mould for obtaining nanostructures formed by nanowires, which are generated in the cavities or pores of the aforementioned nanostructure of the nanomaterial of the invention. Likewise, this document details the use of the nanostructured anodized alumina material as a mould for producing nanostructures.


Patent
CSIC - Institute of Refrigeration, Slovak University of Technology in Bratislava and Helmholtz Center Dresden | Date: 2017-05-24

The present invention relates to a procedure for measuring a d.c. magnetic field by means of a cylindrical device formed by a magnetostrictive core. A d.c. magnetic field is applied and the mechanical deformation on the device caused by the magnetic field is measured and compared with the obtained measurements from previous calibrations to estimate magnetic field intensity values. The invention also relates to an apparatus for measuring a d.c. magnetic field by means of the indicated procedure. The apparatus comprises:- a cylindrical sensor element and an abutment/fixing element, such that the cylindrical sensor element experiences mechanical deformation when exposed to the d.c. magnetic field,- a deformation sensing device configured for detecting the mechanical deformation of the cylindrical sensor element, and- a processing unit configured for determining the intensity of the d.c. magnetic field based on the detected mechanical deformation of the cylindrical sensor element.


Patent
CSIC - Institute of Refrigeration | Date: 2017-05-24

The present invention relates to peptides, namely isolated from olive oil, showing antihypertensive activity. The isolated peptides of the invention comprises at least two cysteines separated by n amino acids, being n an integer of 0, 1, 2, or 3, and consisting of a length between 5 and 10 amino acids. The invention also relates to compositions and functional foods comprising said peptides, as well as its use as a medicament for the treatment diseases associated with high blood pressure and a method for obtaining thereof.


Patent
Technion Research & Development Foundation Ltd. and CSIC - Institute of Refrigeration | Date: 2017-03-29

An optical element for use in power adjustable spectacles comprises a front lens and a back lens which can slide laterally with respect to each other to achieve a first relative position and a second relative position. The optical element may be designed to provide good optical performance for far-distance viewing and for near-distance viewing, or to provide good optical performance for near-distance viewing and for intermediate-distance viewing. In some cases, the front lens and the back lens can slide laterally with respect to each other to achieve a third relative position, and the optical element may be designed to provide good optical performance for far-distance viewing, for intermediate-distance viewing and for near-distance viewing. In all cases, the predetermined addition of the prescription is in the range of 0.50 diopters to 3.00 diopters.


Patent
CSIC - Institute of Refrigeration and National Research Council Italy | Date: 2017-06-14

Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.


Patent
Cellerix S.A. and CSIC - Institute of Refrigeration | Date: 2017-06-28

The present invention provides a population of connective tissue derived cells that respond to interferon-gamma (IFN-) by expressing indolamine-2,3-dioxygenase (IDO) for use in preventing, treating or ameliorating one or more symptoms associated with disorders in which modulation of a subjects immune system is beneficial, including, but not limited to, autoimmune diseases, inflammatory disorders, and immunologically mediated diseases including rejection of transplanted organs and tissues.


Patent
CSIC - Institute of Refrigeration | Date: 2017-03-29

The invention relates to a bacterial strain, Lactobacillus casei IPLA12038 with deposit number CECT 8590, and its use for the degradation of gluten, gliadin or derivative peptides. The strain has been isolated from an acidic dough used to make bread. Its advantages include the ability to use gliadin as nitrogen source, possess peptidase activities involved in the degradation of it and be able to completely degrade the immunotoxic (33) amino acid peptide involved in triggering of celiac disease in a short period of time. The fact of considering it a GRAS and QPS microorganism, isolated from a fermented food, sensitive to antimicrobial gastrointestinal agents and resistant to gastrointestinal conditions tested in vitro, guarantees its use as a probiotic or nutraceutical supplement.


The invention relates to substituted heterocyclic indole derivatives of Formula (I), which act as activators of the AMP-activated protein kinase (AMPK) and to the use of them for the treatment and prevention of diseases or disorders regulated by AMPK. As a result, these compounds can be used for the treatment of inflammatory, autoimmune, cardiovascular, neurological diseases and cancer.

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