Croatian Institute of Public Health

Zagreb, Croatia

Croatian Institute of Public Health

Zagreb, Croatia
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Sekerija M.,Croatian Institute of Public Health | Cukelj P.,Croatian Institute of Public Health
Libri Oncologici | Year: 2015

Ovarian cancer is one of the most lethal malignant cancers in women, mainly because of the late stage at diagnosis. It is the seventh most common cancer in women in the world in incidence (239,000,3.6%) andeighth in mortality (152,000, 4.3%). More developed regions have higher incidence and mortality rates than developing countries. In Croatia, ovarian cancer ranks as the sixth most common cancer in women (430 new cases in 2013) and the sixth malignant cause of death (328 deaths in 2013). Research based on the Croatian National Cancer Registry data also shows that trends of standardized incidence and mortality rates for ovarian cancer in Croatia are relatively stable for the period from 1988 to 2008, while recent studies oncancer survival (EUROCARE-5, CONCORD-2) rank Croatia close to the European mean when it comes to ovarian cancer survival. Ovarian cancer is asignificant public health burden in Croatia. Efforts should be put in education about symptoms, and some modifiable risk factors such as tobacco use, obesity and hormone replacement therapy.


PubMed | University of California at San Francisco, University of Zagreb and Croatian Institute of Public Health
Type: | Journal: Case reports in infectious diseases | Year: 2016

Upon HIV infection diagnosis, an 8-month-old boy was transferred for evaluation of worsening respiratory distress requiring mechanical ventilation.


Milanovic S.M.,University of Zagreb | Milanovic S.M.,Croatian Institute of Public Health | Erjavec K.,Clinical Hospital Sveti Duh | Poljicanin T.,Croatian Institute of Public Health | And 2 more authors.
Psychiatria Danubina | Year: 2015

Background: Depression is a growing public health problem still under-recognised in primary care settings. By focusing primarily on somatic complaints and diseases, general practitioners often fail to identify an underlying mental disorder. The aim of this study was to assess the prevalence of patients with unrecognised depression symptoms in general practice and identify associated socio-demographic factors. Subjects and methods: The study included 769 patients without previous psychiatric disorder who attended their primary care physicians in the Health Centre Zagreb - Zapad in January 2011. Data on patients' age, sex, level of education, marital and employment status were collected. All participants completed The Zung Self-Rating Depression Scale. Results: Among the 25.5% of participants whose Zung score was outside the normal range, 19.38% were mildly, 4.64% moderately, and 0.91% severely depressed. Statistically significant differences were observed among groups defined according to level of education, employment and marital status (p<0.001). Lower Zung scores were found in individuals with a higher level of education, who were unmarried, employed or still undergoing education. Multivariate logistic regression model revealed that older age (p<0.001), unemployment (p=0.001) or unmarried status (p=0.025) were significant predictors of depression symptoms. Conclusions: The study revealed a high prevalence of depression symptoms among primary care patients who had not been previously suspected to have any psychiatric co-morbidity. Awareness of depression symptoms and disorders should be raised among general practitioners, focusing on older, unemployed and unmarried people. © Medicinska naklada.


Vujic M.,University of Rijeka | Pollak L.,Croatian Institute of Public Health
Arhiv za Higijenu Rada i Toksikologiju | Year: 2015

The European Union market is overflown by food supplements and an increasing number of consumers prefer those where bee products play an important part in their composition. This paper deals with complex European Union legislation concerning food supplements based on bee products, placing a special emphasis on their composition, labelling, and safety. Correct labelling of food supplements also represents a great challenge since, in spite of legal regulations in force, there are still open issues regarding the statements on the amount of propolis, which is not clearly defined by the legal framework. One of the key issues are the labels containing health claims from the EU positive list approved by the European Food Safety Authority. Emphasis will also be placed on informing consumers about food, as statements which imply the healing properties of food supplements and their capacity to cure diseases are forbidden. One of the key elements of product safety is HACCP based on the EU Regulations EC 178/02 and 852/2004. Health safety analyses of food supplements with bee products used as raw materials, which are standardised by legal regulations will also be discussed. In the future, attention should also be paid to establishing the European Union "nutrivigilance" system. Croatian experiences in addressing challenges faced by producers, supervisory entities, and regulatory and inspection bodies may serve as an example to countries aspiring to become part of the large European family.


Rezic I.,University of Zagreb | Curkovic L.,University of Zagreb | Ujevic M.,Croatian Institute of Public Health
Talanta | Year: 2010

Characterization of metal threads on historical textile materials is important for preservation of valuable cultural heritage. Obtained results dictate decisions on cleaning, conservation and restoration steps. The most important part of characterization is chemical analysis of originally applied materials, since this enables understanding the nature of chemical and physical degradation and determines the cleaning methods. Methods applied should be non-destructive and sensitive enough to detect trace elements in small sample amounts. The goal of this research was to describe the most useful procedures for fast and simple determination of specific metals of interest. Therefore we propose application of scanning electron microscopy equipped with EDS detector (SEM-EDS) for sample surface analysis and inductively coupled plasma-optical emission spectroscopy (ICP-OES) for chemical analysis of metals threads. For quality insurance reasons, a comparative method applied for chemical analysis was atomic absorption spectrometry (AAS). This combination of methods has proven to be very useful in analysis of historical samples, since SEM-EDS was a simple and non-destructive method which provided information on chemical composition of sample surfaces, while ICP-OES and AAS enabled the full insight into the average chemical composition of samples. Nevertheless, both ICP-OES and AAS were destructive methods which demanded dissolving of samples prior to the analysis. In this work nine different metal fibers collected from historical textile materials were characterized. Proposed methods enabled obtaining information on sample constitution, morphology, topology and chemical composition. © 2010 Elsevier B.V. All rights reserved.


Kaic B.,Croatian Institute of Public Health
Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin | Year: 2010

We describe excretion of measles vaccine strain Schwarz in a child who developed a febrile rash illness eight days after primary immunisation against measles, mumps and rubella. Throat swabs and urine specimens were collected on the fifth and sixth day of illness, respectively. Genotyping demonstrated measles vaccine strain Schwarz (genotype A). If measles and rubella were not under enhanced surveillance in Croatia, the case would have been either misreported as rubella or not recognised at all.


Muslic L.,Croatian Institute of Public Health | Jokic-Begic N.,University of Zagreb
Journal of Psychosomatic Obstetrics and Gynecology | Year: 2016

Objective: The hormonal changes that occur in perimenopause can result in distress for a significant proportion of women years before reaching menopause. Previous studies have suggested that various biopsychosocial characteristics and personality traits contribute to more intense reactions to these hormonal changes. In the present study, we examined the contribution of trait anxiety and anxiety sensitivity in predicting the experience of perimenopausal distress in pre- and early perimenopausal women while controlling for some menstrual experiences. Method: A sample of 660 women aged 35-52 years was selected from a broader online survey of biopsychosocial changes in middle-aged women that considered age, menstrual cycle pattern, physical and mental health, and childbearing experience. Three hierarchical multiple regression analyses were conducted for different age subgroups: women aged 35-40, women aged 41-45 and women aged 46-52. Results: Results indicated that anxiety and anxiety sensitivity, along with a number of features of the menstrual experience, explained 56-66% of the perimenopausal distress variance. Different personality trait predictors were found to be important in different age subgroups. In the youngest and middle subgroups (45 years and younger), trait anxiety was found to be more significant, whereas anxiety sensitivity was found to be more important in explaining perimenopausal distress experienced by women older than 40. Conclusion: Anxiety sensitivity (dimension of psychological concerns) might be an important vulnerability factor in the experience of perimenopausal distress among women closer to menopause, whereas the predisposition to an anxiety response might contribute to perimenopausal distress near the beginning of reproductive hormonal changes. Implications for better understanding the development of perimenopausal distress and psychological intervention are discussed. © 2015 Taylor & Francis.


PubMed | Croatian Veterinary Institute, University of Zagreb and Croatian Institute of Public Health
Type: | Journal: Acta tropica | Year: 2017

Leptospirosis is a geographically widespread and globally underestimated zoonosis that affects humans and variety of animals. To identify trends and possible risk factors, joined medical and veterinary teams investigated epidemiology and epizootiology of leptospirosis in Croatia. Retrospective analysis of data obtained from referent diagnostic laboratories included a total of 1917 human and 123964 animal sera tested in the period from 2009 to 2014. We found high human leptospirosis average incidence rate of 1.53/100000 with clear predominance of male patients older than 40 years (sex ratio M/F:3.2; median age 5115.1years). Statistical analysis revealed seasonal and annual variations of incidence in humans that were primarily associated with favourable weather conditions (temperature 10-19,9C and precipitation above 100mm/m


PubMed | University of Zagreb and Croatian Institute of Public Health
Type: Journal Article | Journal: Journal of psychosomatic obstetrics and gynaecology | Year: 2016

The hormonal changes that occur in perimenopause can result in distress for a significant proportion of women years before reaching menopause. Previous studies have suggested that various biopsychosocial characteristics and personality traits contribute to more intense reactions to these hormonal changes. In the present study, we examined the contribution of trait anxiety and anxiety sensitivity in predicting the experience of perimenopausal distress in pre- and early perimenopausal women while controlling for some menstrual experiences.A sample of 660 women aged 35-52 years was selected from a broader online survey of biopsychosocial changes in middle-aged women that considered age, menstrual cycle pattern, physical and mental health, and childbearing experience. Three hierarchical multiple regression analyses were conducted for different age subgroups: women aged 35-40, women aged 41-45 and women aged 46-52.Results indicated that anxiety and anxiety sensitivity, along with a number of features of the menstrual experience, explained 56-66% of the perimenopausal distress variance. Different personality trait predictors were found to be important in different age subgroups. In the youngest and middle subgroups (45 years and younger), trait anxiety was found to be more significant, whereas anxiety sensitivity was found to be more important in explaining perimenopausal distress experienced by women older than 40.Anxiety sensitivity (dimension of psychological concerns) might be an important vulnerability factor in the experience of perimenopausal distress among women closer to menopause, whereas the predisposition to an anxiety response might contribute to perimenopausal distress near the beginning of reproductive hormonal changes. Implications for better understanding the development of perimenopausal distress and psychological intervention are discussed.


PubMed | University of Split, University of Zagreb, Croatian Institute of Public Health and County Hospital Dubrovnik
Type: | Journal: The Journal of pediatrics | Year: 2016

The Republic of Croatia is a Parliamentary Republic with a population of 4.2 million people that sits on the Adriatic coast within Central Europe. Grossdomestic product is approximately 60% of the European Union average, which in turn, limits health service spending. The health system is funded through universal health insurance administered by the Croatian Health Insurance Fund based on the principles of social solidarity and reciprocity. The children of Croatia are guaranteed access to universal primary, hospital, and specialist care provided by a network of health institutions. Pediatricians and school medicine specialists provide comprehensive preventive health care for both preschool and school-aged children. Despite the Croatian War of Independence in the late 20th century, indicators of child health and measures of health service delivery to children and families are steadily improving. However, similar to many European countries, Croatia is experiencing a rise in the new morbidities and is responding to these new challenges through a whole society approach to promote healthy lifestyles and insure good quality of life for children.

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