Princeton, NJ, United States
Princeton, NJ, United States

Covance Inc. with headquarters in Princeton, New Jersey, is a contract research organization providing drug development and animal testing services. According to its website, it is one of the largest companies of its kind in the world, with annual revenues of over $2 billion, and over 11,000 employees in more than 60 countries. It claims to provide the world's largest central laboratory network. It became a publicly traded company after being spun off by Corning Incorporated in 1996. In 2011 it was listed as one of the top 100 employers by the Diversity Employers Magazine.Under the name Covance Research Products Inc., based in Denver, Pennsylvania, the company also deals in the import, breeding and sale of laboratory animals. It breeds dogs, rabbits, guinea pigs, non-human primates, and pigs, and runs the largest non-human primate laboratory in Germany. The company became the subject of controversy following allegations in 2003–2005 by the British Union for the Abolition of Vivisection and People for the Ethical Treatment of Animals that non-human primates were being abused in its laboratories in Germany and the United States. No violations of the law were found by the authorities in the first case, and a small fine was levied in the second. In response, the company drew up a new welfare code to guide its treatment of laboratory animals.On November 3rd, 2014, Labcorp announced it would be purchasing Covance for $6.1bn. Wikipedia.


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BURLINGTON, N.C.--(BUSINESS WIRE)--LabCorp® (NYSE: LH) today announced it will participate at the Bank of America Merrill Lynch 2017 Health Care Conference. LabCorp’s presentation is scheduled for Tuesday, May 16, 2017, at 10:40 a.m. PT. A live audio webcast of the presentation will be available via the Company website at www.labcorp.com and archived for replay. LabCorp (NYSE: LH), an S&P 500 company, is a leading global life sciences company that is deeply integrated in guiding patient care, providing comprehensive clinical laboratory and end-to-end drug development services. With a mission to improve health and improve lives, LabCorp delivers world-class diagnostic solutions, brings innovative medicines to patients faster and uses technology to provide better care. LabCorp reported net revenues of nearly $9.5 billion for 2016 through the contributions of 52,000 employees in approximately 60 countries. To learn more about LabCorp, visit www.labcorp.com, and to learn more about Covance Drug Development, visit www.covance.com. This press release contains forward-looking statements including with respect to estimated 2017 guidance and the impact of various factors on operating and financial results. Each of the forward-looking statements is subject to change based on various important factors, including without limitation, competitive actions in the marketplace, and adverse actions of governmental and other third-party payers. Actual results could differ materially from those suggested by these forward-looking statements. The Company has no obligation to provide any updates to these forward-looking statements even if its expectations change. Further information on potential factors that could affect operating and financial results is included in the Company’s Form 10-K for the year ended December 31, 2016, and subsequent Forms 10-Q, including in each case under the heading risk factors, and in the Company’s other filings with the SEC. The information in this press release should be read in conjunction with a review of the Company’s filings with the SEC including the information in the Company’s Form 10-K for the year ended December 31, 2016, and subsequent Forms 10-Q, under the heading MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS.


New Research Identifies Need for Patient-Centric Clinical Trials and Role for CROs New Research Identifies Patient-centric Strategies for Clinical Development with over 125 Global Research Opinion Leaders. Recognizing the upcoming need of distinct patient populations and understanding how CROs can play a role in running patient-centric trials, Life Science Strategy Group (LSSG) conducted research with 126 global opinion leaders involved in preclinical and clinical research at small, mid-sized, and large biopharmaceutical companies. LSSG found that up to 87% of respondents are discussing patient-centric approaches to clinical development, with half of the surveyed companies expecting to implement patient-centric approaches for clinical development within the next 1-3 years. "It is important to realize where Pharma is in its implementation of patient-centric strategies for clinical development today and to understand their needs in the future," said Jon Meyer, Life Science Strategy Group’s CRO Industry Practice Leader. Further, the research identifies that CROs need to play an increasing role as an enabler of success in patient-centric clinical trials. "Sponsors would like to see CROs research new and existing technologies such as data collection devices, patient-oriented websites and applications, and sample storage options, that enhance patient-centric trial approaches. This study gives us a glimpse at which CROs are best prepared to meet Pharma’s needs today and in the future," said Meyer. To learn more about LSSG’s new study examining patient-centric development trends as well as which CROs such as Covance, ICON, inVentiv Health Clinical, INC Research, Parexel, PPD, PRA International and QuintilesIMS are best prepared to address the new development needs, please contact Life Science Strategy Group or click on the link below. http://lifesciencestrategy.com/publications/cro-industry/pubs-cro-patient-centric-april-2017/ About Life Science Strategy Group, LLC Life Science Strategy Group, LLC specializes in strategic consulting and market research engagements across a variety of therapeutic, technology and service industries including contract research services, pharmaceutical, biotechnology, medical devices, diagnostics and drug discovery. Menlo Park, CA, April 28, 2017 --( PR.com )-- Life Science Strategy Group (LSSG) the leading strategic consulting firm to the CRO industry, is pleased to announce the results of a new 2017 study, "Patient-Centric Clinical Development Status and the Role of the Contract Research Organization (CRO)." which focuses on the current status and emerging trends of patient-centric clinical trials and the role CROs will play.Recognizing the upcoming need of distinct patient populations and understanding how CROs can play a role in running patient-centric trials, Life Science Strategy Group (LSSG) conducted research with 126 global opinion leaders involved in preclinical and clinical research at small, mid-sized, and large biopharmaceutical companies. LSSG found that up to 87% of respondents are discussing patient-centric approaches to clinical development, with half of the surveyed companies expecting to implement patient-centric approaches for clinical development within the next 1-3 years."It is important to realize where Pharma is in its implementation of patient-centric strategies for clinical development today and to understand their needs in the future," said Jon Meyer, Life Science Strategy Group’s CRO Industry Practice Leader.Further, the research identifies that CROs need to play an increasing role as an enabler of success in patient-centric clinical trials. "Sponsors would like to see CROs research new and existing technologies such as data collection devices, patient-oriented websites and applications, and sample storage options, that enhance patient-centric trial approaches. This study gives us a glimpse at which CROs are best prepared to meet Pharma’s needs today and in the future," said Meyer.To learn more about LSSG’s new study examining patient-centric development trends as well as which CROs such as Covance, ICON, inVentiv Health Clinical, INC Research, Parexel, PPD, PRA International and QuintilesIMS are best prepared to address the new development needs, please contact Life Science Strategy Group or click on the link below.About Life Science Strategy Group, LLCLife Science Strategy Group, LLC specializes in strategic consulting and market research engagements across a variety of therapeutic, technology and service industries including contract research services, pharmaceutical, biotechnology, medical devices, diagnostics and drug discovery. Click here to view the list of recent Press Releases from Life Science Strategy Group, LLC


BURLINGTON, N.C.--(BUSINESS WIRE)--LabCorp® (NYSE: LH) today announced that the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, or HSR Act, applicable to LabCorp’s acquisition of Pathology Associates Medical Laboratories, LLC (PAML) has expired. As previously announced, LabCorp, Providence Health & Services (Providence) and Catholic Health Initiatives (CHI) entered into a definitive agreement for LabCorp to acquire all of the ownership interests in PAML, one of the nation's premier medical reference laboratories and a healthcare solutions company jointly owned by Providence and CHI. Expiration of the waiting period satisfies one of the conditions necessary to complete the pending acquisition. The transaction remains subject to other closing conditions, which are expected to be satisfied in the near future. LabCorp (NYSE: LH), an S&P 500 company, is a leading global life sciences company that is deeply integrated in guiding patient care, providing comprehensive clinical laboratory and end-to-end drug development services. With a mission to improve health and improve lives, LabCorp delivers world-class diagnostic solutions, brings innovative medicines to patients faster and uses technology to improve the delivery of care. LabCorp reported net revenues of nearly $9.5 billion for 2016 through the contributions of 52,000 employees in approximately 60 countries. To learn more about LabCorp, visit www.labcorp.com, and to learn more about Covance Drug Development, visit www.covance.com. This press release contains forward-looking statements including with respect to estimated 2017 guidance and the impact of various factors on operating and financial results. Each of the forward-looking statements is subject to change based on various important factors, including without limitation, competitive actions in the marketplace, and adverse actions of governmental and other third-party payers. Actual results could differ materially from those suggested by these forward-looking statements. The Company has no obligation to provide any updates to these forward-looking statements even if its expectations change. Further information on potential factors that could affect operating and financial results is included in the Company’s Form 10-K for the year ended December 31, 2016, and subsequent Forms 10-Q, including in each case under the heading risk factors, and in the Company’s other filings with the SEC. The information in this press release should be read in conjunction with a review of the Company’s filings with the SEC including the information in the Company’s Form 10-K for the year ended December 31, 2016, and subsequent Forms 10-Q, under the heading MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS.


Drug Discovery Informatics Market is accounted for $1.91 billion in 2015 and is expected to reach $6.94 billion by 2022 growing at a CAGR of 17.5% from 2015 to 2022Pune , India - April 25, 2017 /MarketersMedia/ — Drug Discovery Informatics Industry Description Global Drug Discovery Informatics Market is accounted for $1.91 billion in 2015 and is expected to reach $6.94 billion by 2022 growing at a CAGR of 17.5% from 2015 to 2022. The rising demand for computational technology is the primary factor favouring the market growth. Furthermore, Drug discovery industry and rising number of technologically advanced products are the key drivers for the Drug Discovery Informatics market. However, Lack of information technology and critical attributes of data evaluation are limiting the market growth. The recent trends in Drug Discovery Informatics are considerable shift observed from traditional in-vitro drug development to computer aided drug designing, as costly failures of late drug development increases the use of in-silico models for early ADME/Toxicity screening. Sequence analysis platforms services accounted the largest revenue share and are expected to continue and dominate the market over the forecast period. North America commanded the largest share driven by the increasing demand for computational technology. However, Asia Pacific is projected to register the fastest growth over the forecast period owing to technological developments in the software and drug nano technology fields carried out in the developing economies. Request for Sample Report @ https://www.wiseguyreports.com/sample-request/456587-drug-discovery-informatics-global-market-outlook-2015 Some of the key players in the market include ChemAxon, GVK Biosciences, Jubilant Biosys, Selvita, Certara, Infosys, Albany Molecular Research Inc., BoehringerIngelheim GmBh,, DiscoverX, Charles River Laboratories, Covance, Collaborative Drug Discovery Inc., Novo Informatics, UCB and Evotec. Modes Covered: • In-house Informatics • Outsourced Informatics Services Covered: • Molecular Modelling • Sequence Analysis Platforms • Docking • Clinical Trial Data Management • Other Services Leave a Query @ https://www.wiseguyreports.com/enquiry/456587-drug-discovery-informatics-global-market-outlook-2015 Regions Covered: • North America o US o Canada o Mexico • Europe o Germany o France o Italy o UK o Spain o Rest of Europe • Asia Pacific o Japan o China o India o Australia o New Zealand o Rest of Asia Pacific • Rest of the World o Middle East o Brazil o Argentina o South Africa o Egypt What our report offers: - Market share assessments for the regional and country level segments - Market share analysis of the top industry players - Strategic recommendations for the new entrants - Market forecasts for a minimum of 7 years of all the mentioned segments, sub segments and the regional markets - Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations) - Strategic recommendations in key business segments based on the market estimations - Competitive landscaping mapping the key common trends - Company profiling with detailed strategies, financials, and recent developments - Supply chain trends mapping the latest technological advancements Buy now @ https://www.wiseguyreports.com/checkout?currency=one_user-USD&report_id=456587 Continued... Contact Us: Sales@Wiseguyreports.Com Ph: +1-646-845-9349 (US) Ph: +44 208 133 9349 (UK) Contact Info:Name: NORAH TRENTEmail: sales@wiseguyreports.comOrganization: WISE GUY RESEARCH CONSULTANTS PVT LTDAddress: Office No. 528, Amanora Chambers Magarpatta Road, Hadapsar Pune - 411028Phone: +91 841 198 5042Source URL: http://marketersmedia.com/drug-discovery-informatics-market-2017-global-analysis-opportunities-and-forecast-to-2022/190033For more information, please visit https://www.wiseguyreports.com/sample-request/456587-drug-discovery-informatics-global-market-outlook-2015Source: MarketersMediaRelease ID: 190033


TORONTO, ON--(Marketwired - April 25, 2017) - On Monday, May 8, 2017, Xtalks will host a complimentary webinar with a panel of speakers from Covance, featuring: Amy Franke, Senior Director of Strategy and Planning, Bridget (Fitzsimmons) Weeks, Director of Project Management (Oncology) and Montessa Lizaso, Senior Data Analyst for Strategy and Planning (Oncology).


Grant
Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: HEALTH.2010.4.2-9-1 | Award Amount: 9.40M | Year: 2011

In the development of products for use by humans it is vital to identify compounds with toxic properties at an early stage of their development, to avoid spending time and resource on unsuitable and potentially unsafe candidate products. Human pluripotent stem cell lines offer a unique opportunity to develop a wide variety of human cell-based test systems because they may be expanded indefinitely and triggered to differentiate into any cell type. SCR&Tox aims at making use of these two attributes to provide in vitro assays for predicting toxicity of pharmaceutical compounds and cosmetic ingredients. The consortium has been designed to address all issues related with biological and technological resources to meet that goal. In order to demonstrate the value of pluripotent stem cells for toxicology, the consortium will focus on four complementary aspects: Relevance i.e. establishing and maintaining discrete cell phenotypes over long-term cultures; providing large versatility to adapt to assays of specific pathways. Efficiency for i) automated cell production and differentiation, ii) cell engineering for differentiation and selection iii) multi-parametric toxicology using functional genomic, proteomic and bioelectronics. Extension i.e. i) scalability through production of cells and technologies for industrial-scale assays, and ii) diversity of phenotypes (5 different tissues), and of genotypes (over 30 different donors). Normalization validation and demonstration of reproducibility and robustness of cell-based assays on industrial-scale platforms, to allow for secondary development in the pharmaceutical and cosmetic industry. SCR&Tox will be intricately associated to other consortia of the Alternative Testing call, sharing biological, technological and methodological resources. Proof of concept of the proposed pluripotent stem cell-based assays for toxicology will be provided on the basis of toxicity pathways and test compounds identified by other consortia.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH.2011.1.4-3 | Award Amount: 8.73M | Year: 2011

The consortium aims to develop and produce an Anticalin, a member of a novel high-affinity scaffold derived from the lipocalin protein family. The Anticalin is specific for hepcidin which is a central regulator of iron homeostasis, and will be used to antagonize hepcidin for the treatment of anemia of chronic disease (ACD). Anticalins are genetically modified lipocalins that can target almost any desired molecule. Unlike Immunoglobulins, they can be produced at low cost in microbial expression systems, are expected to be non immunogenic and offer therapeutic advantages where antibody effector functions are not desired. ACD, the most frequent anemia in hospitalized patients, develops in subjects suffering from infections, inflammatory and auto-immune disease, cancer and chronic kidney disease. It is often successfully treated by administering Erythropoiesis-Stimulating Agents. However, a significant number of patients are hypo- or non-responsive to ESA. Anti-hepcidin therapies, alone or together with ESAs, may improve anemia and the patients erythropoietic response and enable the use of no or even much lower ESA doses, avoiding the potential detrimental effects of high doses of ESA. The Consortium has already generated proof-of-concept data in an animal model with early candidates. The project aims at identifying, validating, and developing a specific, high affinity drug candidate based on the lipocalin scaffold as promising alternatives to immunoglobulins and a therapeutic approach based on the neutralization of hepcidin. Animal models will be developed and utilized to characterize pharmacokinetic and pharmacodynamic relationships, optimize dosing, to determine safety, biomarker responses and potential synergy with ESAs. Furthermore, production processes will be optimized leading to a scalable GMP process which provides material for preclinical and clinical studies to establish the safety, tolerability, and PK/PD of an Anticalin hepcidin blocker (Phase Ia/b).


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: NMBP-10-2016 | Award Amount: 5.85M | Year: 2017

Lysosomal storage disorders (LSD) diseases are a group of rare diseases that currently lack a definitive cure. LSD incidence is about 1:5,000 - 1:10,000, representing a serious global health problem. In the case of Fabry LSD Disease (FD), the deficiency in -Galactosidase A (GLA) enzyme activity results in the cellular accumulation of neutral glycosphingolipids, leading to widespread vasculopathy with particular detriment to the kidneys, heart and nervous system. The current treatment for FD is the Enzyme Replacement Therapy (ERT), in which free GLA recombinant protein is administered intravenously to patients. ERT exhibits several drawbacks mainly related to the instability, high immunogenicity and low efficacy of the exogenously administered GLA to cross biological barriers, such as cell membranes and BBB.The aim of Samrt-4-Fabry project is to achieve excellent quality control over the assembly of the different molecular components of a new liposomal nanoformulation of GLA, nano-GLA, for the treatment of Fabry disease. Nanoformulated GLA has already shown to have better PK/PD profile than free GLA and higher efficacy in vivo. Smart-4-Fabry project will advance nano-GLA from an experimental PoC (TRL3) to preclinical regulatory phase (TRL5-6). A one-step method based on the use of green cCO2, will be used for the manufacturing of this novel nanoformulation under GMPs. The final GLA nanoformulation will have tailored transport of GLA through cell membranes and BBB. Fulfillment of Smart-4-Fabry will impact on a major health problem, the existence of new therapies for rare diseases, which constitutes a priority societal challenge as shown in the H2020 Work Programmes. Another important impact is related to its contribution to support the European Strategy for KETs, which aims to reverse the decline in manufacturing as this will stimulate growth and jobs. Smart-4-Fabry is strongly focusing on three KETs: nanotechnology, industrial biotechnology and advanced materials.

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