Stuttgart Muhlhausen, Germany
Stuttgart Muhlhausen, Germany

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Browse 162 tables and 52 figures, 13 Company profiles spread across 181 pages available at The global continuous manufacturing market is expected to reach USD 650.4 million by 2022 from USD 348.5 million in 2017, at a CAGR of 13.3%. The market is segmented on the basis of product, application, end user, and geography. The product segment includes integrated systems, semi-continuous systems, and controls. The integrated systems segment is expected to account for the largest share of the continuous manufacturing market in 2017. The integrated systems enable end-to-end manufacturing to convert raw materials into final products. In addition, these systems save substantial cost and time by integrating various pharmaceutical processes in a single system. By application, the end product manufacturing segment is estimated to account for the largest share of the market, in 2017. FDA approval for certain drugs manufactured by the continuous process is the primary factor driving the growth of this segment. On the basis of end user, the full-scale manufacturing companies are expected to hold the highest share of the market, in 2017. The large share of this segment can primarily be attributed to the increasing adoption of continuous technologies by pharmaceutical manufacturing companies and CMOs to address the challenges related to product quality, drug supply, and operational costs. The geographic segments in this report include North America, Europe, Asia-Pacific, and RoW. Of these, the North American segment is expected to account for the largest share of the market in 2017. This large share can primarily be attributed to the support from regulatory bodies, initiation by leading pharmaceutical companies, and the need for pharmaceutical manufacturers to reduce rising operational costs and eliminate issues related to the inconsistent quality of pharmaceutical products produced through batch manufacturing. Product launch was the dominant strategy adopted by key industry participants to increase their market share and cater to unmet needs. Major players include GEA Group AG (Germany), Thermo Fisher Scientific Inc. (U.S.), Bosch Packaging Technology (Germany), Coperion GmbH (Germany), and Glatt GmbH (Germany). Other players include KORSCH AG (Germany), Munson Machinery Company, Inc. (U.S.), L.B. Bohle Maschinen + Verfahren Gmbh (Germany), Gebruder Lodige Maschinenbau GmbH (Germany), Baker Perkins Ltd. (U.K.), Scott Equipment Company (U.S.), and Sturtevant, Inc. (U.S.). Order a copy of Continuous Manufacturing Market By Product (Integrated system, Semi-continuous (Granulator, Coater, Blender), Control), Application (API, End Product (Solid Dosage)), End User (R&D Department (CRO), Pharmaceutical Companies, CMO) - Global Forecast to 2022 Research Report at Nuclear Medicine/Radiopharmaceuticals Market by Type (Diagnostic (SPECT - Technetium, PET - F-18), Therapeutic (Beta Emitters - I-131, Alpha Emitters, Brachytherapy - Y-90) & by Application (Oncology, Thyroid, Cardiology) - Global Forecasts to 2021. Explore more reports on Pharmaceuticals market Research at is an online market research reports library of 500,000+ in-depth studies of over 5000 micro markets. Not limited to any one industry, offers research studies on agriculture, energy and power, chemicals, environment, medical devices, healthcare, food and beverages, water, advanced materials and much more.

According to a new research report by Transparency Market Research (TMR), the degree of competition in the Global Pharmaceutical Hot Melt Extrusion Market is very high. The presence of a large number of participants characterizes the market, which demonstrates a fragmented landscape. Led by Leistritz AG, Milacron Holdings Corp., Xtrutech Ltd., Coperion GmbH, and Gabler GmbH & Co. KG, the market is expected to continue with intense rivalry between them in the near future. The leading players are likely to invest heavily in R&D initiatives over the years to come, in order to meet the demand of consumers by offering innovative products, states the report. TMR estimates the opportunity in the global market for pharmaceutical hot melt extrusion, which was worth US$26.6 mn in 2015, to expand at a CAGR of 3.90% between 2016 and 2024 and reach a value of US$36.4 mn by the end of the period of the forecast. During the same period of time, the market volume is anticipated to swell at a CAGR of more than 4.7%, boosting the market significantly. Twin screw extruders have emerged as the most valued products in this market and is predicted to continue to enjoy a high demand over the forthcoming years. On Backdrop of Large Pool of Leading Players, North America to Retain its Lead The worldwide market for pharmaceutical hot melt extrusion boasts of a widespread presence across North America, Asia Pacific, Latin America, Europe, and the Middle East and Africa. In this research report, a regional analysis of this market has also been provided to the readers. According to the study, North America led the global market with a share of nearly 38% in 2015. Researchers predicts this regional market to maintain its dominance throughout the forecast period, thanks to the presence of a large pool of established players, especially in the U.S. The Europe market for pharmaceutical hot melt extrusion has also been witnessing steady growth and is predicted to continue doing so in the near future on account of the increasing demand for improved medical equipment and the growing adoption of extruders. Asia Pacific, However, will present the most lucrative growth opportunities for players in this market over the forthcoming years, thanks to rising number of research and development initiatives and the improving situation of the healthcare facilities in emerging economies, such as China, India, and Japan. The heightening standard of medical and healthcare infrastructure and the increase in government initiatives is also expected to impact this regional market in the forthcoming years. Rising Awareness among Consumers to Reflect Positively on Demand for Pharmaceutical Hot Melt Extrusion According to an analyst at TMR, "the rising awareness regarding the benefits hot melt extrusion offers over traditional processing techniques, is the key factor behind the significant growth of the global pharmaceutical hot melt extrusion market." The operating parameters in hot melt extrusion can be easily changed, the segmented screw elements allow agitator designs to be easily optimized to suit a particular application, and the die plates can also be easily exchanged to alter the extrudate diameter. All these characteristics are having a positive influence on the demand for pharmaceutical hot melt extrusion, leading to a significant rise in this market. However, the rising concerns over the quality and the non-compliance of regulatory requirements may limit the growth of this market to some extent over the next few years, notes the research study. The study presented here is based on a report by Transparency Market Research (TMR), titled "Pharmaceutical Hot Melt Extrusion Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024." The market has been segmented as below: Healthcare CMO Market (Service - Pharmaceutical Contract Manufacturing Services (Active Pharmaceutical Ingredients (API) Manufacturing, Final Dosage Form (FDF) Manufacturing, and Packaging) and Medical Device Contract Manufacturing Services (Outsourcing Design, Device Manufacturing (Material Process Services, Electronic Manufacturing Services, and Finished Products), and Final Goods Assembly) - Global Industry Analysis, Size, Share, Trends, Growth and Forecast 2013 - 2019 Single-use Bioprocessing Systems Market - (Product - Bioreactors & Fermenters, Mixers, Bags, Bioprocess Containers, Filtration Devices, Tubing, Sampling Systems, Connectors & Clamps, Probes & Sensors; End User - Pharmaceutical, Biotechnology, CRO & CMO, and Academic & Research Institutes; Application - Monoclonal Antibody Production, Vaccine Production, Plant Cell Cultivation, and Patient Specific Cell Therapies) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024 Medical Education Market (Type of Training - Cardiothoracic, Neurology, Orthopedic, Oral and Maxillofacial, Pediatric, Radiology, Laboratory; Mode of Education - On-campus, Distance, Online) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024 Transparency Market Research (TMR) is a U.S. based provider of syndicated research, customized research, and consulting services. TMR's global and regional market intelligence coverage includes industries such as pharmaceutical, chemicals and materials, technology and media, food and beverages, and consumer goods, among others. Each TMR research report provides clients with a 360-degree view of the market with statistical forecasts, competitive landscape, detailed segmentation, key trends, and strategic recommendations.

Coperion GmbH | Date: 2012-02-06

A device for producing granules has a water-cooled granulating mechanism for producing plastics material granules. A discharge line arranged downstream of the granulating mechanism discharges a starting mixture flow and a granule heat exchanger arranged downstream of the discharge line controls the temperature of the mixture containing the plastics material granules and cooling water using parallel fluid passages. The granule heat exchanger has an inlet and an outlet for a transmission heat exchanger medium. A drying mechanism arranged downstream of the granule heat exchanger dries the plastics material granules. The device also may have an energy recovery mechanism arranged downstream of the discharge line for recovering energy from a recovery cooling water flow, containing at least a part of the cooling water of the starting mixture flow. The device uses waste heat, transmitted to the cooling water to increase the performance of the device and improve the energy efficiency thereof.

In a processing plant for producing plastics material granulate, the start-up takes place in such a way that a screw machine is firstly driven by means of a drive device and then plastics material to be processed is fed by means of a metering device into the screw machine. At least one conveying position of the plastics material in the screw machine is determined by means of a control device by evaluating at least one measuring signal. Depending on the conveying position determined, a granulating device is activated and put into operation. The method according to the invention allows a direct start-up of the processing plant without the use of a start-up valve. This ensures an easy and safe start-up of the processing plant.

A loading system for loading bulk material from a bulk material production plant onto a ship has at least one stationary intermediate storage container for receiving the bulk material from the bulk material production plant. A first loading conveying device is used to convey the bulk material from the bulk material production plant into the intermediate storage container. A second loading conveying device is used to convey the bulk material from the intermediate storage container into the ship. An unloading system for loading bulk material from a ship onto transporters has a stationary intermediate storage container for receiving the bulk material from the ship. Two unloading conveying devices are used to convey the bulk material, from the ship into the intermediate storage container and, from the intermediate storage container into the transporters.

A device, to homogenise plastics material melts, has a homogenising element with a plurality of flow channels, which differ with respect to at least one feature from the group length, cross sectional area and cross sectional shape. When flowing through the homogenising element, the plastics material melt is divided into a plurality of part streams, which, in each case, flow through an associated flow channel. When leaving the respective flow channel the part streams have different flow speeds so the plastics material melt is expanded and sheared on transition to a uniform flow. As a result, a homogenisation of the plastics material melt takes place in a simple, efficient and effective manner.

A gearbox assembly for a twin-screw extruder comprises a speed change gearbox for adjusting a screw shaft speed of two screw shafts of the twin-screw extruder, a distribution gearbox allowing the screw shafts to be coupled thereto, and a speed reduction gearbox. The speed change gearbox and the speed reduction gearbox are configured such as to be separable from each other, wherein the speed change gearbox is arranged at a driving end while the speed reduction gearbox couples the speed change gearbox to the distribution gearbox. Due to the fact that the speed change gearbox is configured as an individual gearbox unit arranged at the driving end, an adjustment of the screw shaft speed is easily possible by replacing the speed change gearbox. As a result, a high flexibility and productivity are obtained in the operation of the twin-screw extruder.

A processing installation for the processing of bulk material has a vacuum filter insert for degassing of the bulk material. The vacuum filter insert is arranged in a casing of a screw machine downstream of the feed opening thereof and is provided with at least one filter element so that the vacuum filter insert forms a gas-permeable wall portion which defines the at least one casing bore of the screw machine. Seen in a degassing direction, a protective element comprising a plurality of through-openings is arranged upstream of the at least one filter element. The protective element acts as a granule protection for the at least one filter element and prevents granular bulk material from damaging the at least one filter element. As a result, the vacuum filter insert has a longer service life, thus ensuring a long operating time for the processing installation without interruptions.

A cellular wheel sluice has a housing, a feed shaft opening therein and an outlet shaft opening out therefrom. Arranged between the shafts is a cellular wheel. The latter is arranged so as to be rotatably drivable about a horizontal rotational axis in a cylindrical cellular wheel housing portion. A cellular wheel drive shaft non-rotatably connected to the cellular wheel is rotatably mounted in the housing. A pressure drop is applied during operation of the cellular wheel sluice, a higher pressure being present in the feed shaft than in the outlet shaft. The cellular wheel is operated during the product conveyance between the feed shaft and the outlet shaft at a rotational speed in such a way that an outer periphery of the cellular wheel reaches a speed that is greater than 0.6 m/s.

A processing installation for devolatilization of polymer melts comprises a first extruder and a second extruder arranged downstream thereof in a direction of conveyance. The first extruder comprises several rotatably drivable first shafts which are provided with first treatment members and several devolatilization zones with associated devolatilization ports. Correspondingly, the second extruder comprises several rotatably drivable second shafts which are provided with second treatment members and several second devolatilization zones with associated devolatilization ports. The first treatment members have an external diameter which is smaller than or equal to that of the second treatment members. A devolatilization unit is arranged in a transfer zone which interconnects the extruders. The devolatilization unit comprises a perforated plate and a clearance arranged downstream in the direction of conveyance. A control unit is configured in such a way that when the processing installation is operated, the speed of the second shafts is lower than the speed of the first shafts. The processing installation allows a high devolatilization performance and a high polymer throughput to be achieved at the same time. A throttle is arranged in the transfer zone upstream of the devolatilization unit when seen in the direction of conveyance, with the position of the throttle being adjustable by means of the control unit.

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