Consortium for Science, Technology of Materials and University of Florence | Date: 2017-01-04
The present invention relates to molecules of formula (I) where R1 = -SO3H, -PO3H, -PO2(OH)2, -OPO2H2, -NHSO3H, -S (N=H)Me, SH, SR o guanidyl; R = C1-4 alkyl, phenyl or 5 or 6 membered aromatic nitrogen heterocycles; n = 1, 2, 3, 4 o 5; X = C=0, C(OH)H, C(OAIk)H, C=S, CH2; Alk = C1-6 alkyl linear, branched or cyclic, optionally hydroxylated or polyhydroxylated; their preparation and use as analgesics and in the treatment of pain induced by chemotherapies.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: LCE-21-2015 | Award Amount: 3.74M | Year: 2016
The transition to a low carbon economy needs to achieve multiple aims: competitiveness, protection of the environment, creation of quality jobs, and social welfare. Thus policy-makers and other key stakeholders require tools that need to focus beyond the energy sector by including these other domains of economy, society and the environment. Currently, most available tools lack integration of these important areas despite being tightly connected to the energy sector. Moreover, current energy modelling tools often lack documentation, transparency and have been developed for a specialized insider audience, which makes validation and comparison of results as well as independent review impossible. Our project aims to solve the current needs of integration and transparency by developing a leading-edge policy modelling tool based on WoLiM, TIMES and LEAP models and incorporating Input-Output Analysis, that allows for accounting of environmental, social and economic impacts. The modular design of the tool will take into account the necessary flexibility to deal with different levels and interests of stakeholders at great sectorial and spatial detail. Finally, transparency will be achieved through an open access freeware distribution of the model based on the open access programming language (Python), providing a detailed user manual, addressed to a wider non-specialist audience, and including free internet courses and learning materials.
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ICT-25-2015 | Award Amount: 1.12M | Year: 2015
The objective of this project is to elaborate a new roadmap for Nanoelectronics, focused on the requirements of European semiconductor and applications industry, and the advanced concepts developed by Research centers in order to achieve an early identification of promising novel technologies, and cover the R&D needs all along the innovation chain. The final result will be a roadmap for European micro- and nano-electronics, covering all TRL, with a clear identification of short, medium and long term objectives. The roadmap will be divided into main technology sectors and include also cross-functional enabling domains. A proper dissemination of results will take place through the close relationship of the project with the leading European organizations in the field of micro- and nano-electronics, and sanity checks are foreseen during the project with the users world.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: WATER-1b-2015 | Award Amount: 9.80M | Year: 2016
The aim of the project is to implement and demonstrate at large scale the long-term technological and economic feasibility of an innovative, sustainable and efficient solution for the treatment of high salinity wastewater from the F&D industry. Conventional wastewater treatments have proven ineffective for this kind of wastewater, as the bacterial processes typically used for the elimination of organic matter and nutrients are inhibited under high salinity contents. Therefore, generally combinations of biological and physicochemical methods are used which greatly increase the costs of the treatment, making it unaffordable for SMEs, who voluntarily decide not to comply with EU directives and discharge without prior treatment, causing severe damage to the environment. The solution of SALTGAE to this issue consists in the implementation of innovative technologies for each step of the wastewater treatment that will promote energy and resource efficiency, and reduce costs. Amongst these, the use of halotolerant algae/bacteria consortiums in HRAPs for the elimination of organic matter and nutrients stands out for its high added value: not only will it provide an effective and ecological solution for wastewater treatment, but also it will represent an innovative way of producing algal biomass, that will subsequently be valorized into different by-products, reducing the economic and environmental impact of the treatment. Moreover, the project will also address cross-cutting barriers to innovation related to wastewater by developing a platform for the mobilization and networking of stakeholders from all the different sectors related to wastewater, and for the dissemination of results, enabling the development of a common roadmap for the alignment of legislation, regulation and pricing methodologies and promoting financial investment and paradigm shift in perception from wastewater treatment to resource valorisation.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FOF-13-2016 | Award Amount: 3.24M | Year: 2016
The aim of DREAM is to significantly improve the performances of laser Powder Bed Fusion (PBF) of titanium, aluminium and steel components in terms of speed, costs, material use and reliability, also using a LCA/LCC approach, whilst producing work pieces with controlled and significantly increased fatigue life, as well with higher strength-to-weight ratios. DREAM targets the development of a competitive supply chain to increase the productivity of laser-based AM and to bring it a significant step further towards larger scale industrial manufacturing. In order to upscale the results and to reach an industrial relevant level of productivity, the project is focused on the following four main challenges (i) Part modeling and topology optimization (ii) Raw material optimization to avoid powder contamination (iii) Process optimization, including innovations of the control software of the AM machine, to enable high throughput production (iv) Setup of laser-PBF of nanostructured Titanium alloys with unchanged granulometric dimension for an additional push to higher productivity, since nanostructured metal powders can be sintered with lower energy input and faster speed. The project, thanks to the three end-users involved, is focused on components for prosthetic, automotive and moulding applications to optimize the procedure for three different materials, respectively titanium, aluminium and steel.
Agency: European Commission | Branch: H2020 | Program: BBI-IA-DEMO | Phase: BBI.VC3.D5-2015 | Award Amount: 15.54M | Year: 2016
Approximately one third of all food produced globally is wasted every year throughout the whole value chain-from farmers to consumers. To extract the significant amounts of valuable compounds contained in these wastes, AgriMax will combine affordable and flexible processing technologies (ultrasound assisted and solvent extraction, filtration, thermal and enzymatic treatments) for the valorization of side streams from the horticultural culture and food processing industry to be used in a cooperative approach by local stakeholders. Through the selection of case-scenarios previously developed to a pilot scale by the participating RTOs and their industrial transfer in new applications as food additives, packaging and agricultural materials among others, the project will disclose the holistic potential of four new agro-value chains (residues and by products from the culture and processing of tomato, cereals, olives, potato). Any by-product generated along the production cycle will be valorized in a cascade manner to reach over 40% of high value use of the waste. This will lead to additional production of active ingredients in lower concentration, but also fibres, biogas and fertilizers from the left biomass (the latter with the aim of being used in closed loop in the culture of the crops used in the project to prevent soil impoverishing). An LCA and LCC will also study the best approach to minimize the environmental impact of the new value chains without jeopardizing the cost effectiveness of the operations. The pilot multi-feedstock bio-refinery processes will be validated in two demonstration sites in Spain and Italy. Societal, ethical, safety, techno-feasibility and regulatory aspects will be studied. Last but not least, a business model and platform for communication between the potential raw materials suppliers will be set up to maximize the use of the cooperative treatment plants throughout the year.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: NMP-21-2014 | Award Amount: 6.97M | Year: 2015
The project NANO-CATHEDRAL aims at developing, with a nano-metric scale approach, new materials, technologies and procedures for the conservation of deteriorated stones in monumental buildings and cathedrals and high value contemporary architecture, with a particular emphasis on the preservation of the originality and specificity of materials. The objective is providing key tools for restoration and conservation: On representative lithotypes On European representative climatic areas With a time-scale/environmental approach With technology validated in relevant environment (industrial plant and monuments) Exploiting results also on modern stone made buildings A general protocol will be defined for the identification of the petrographic and mineralogical features of the stone materials, the identification of the degradation patterns, the evaluation of the causes and mechanisms of alteration and degradation, including the correlations between the relevant state of decay and the actual microclimatic and air pollution conditions. Moreover, innovative nano-materials will be developed suitable for: Surface consolidation: in this case water-based formulations based on nano-inorganic or nano-hybrid dispersions such as nano-silica, nano-titania, nano-hydroxyapatite, nano-calcite and nano-magnesia as well as their synergic combinations with organic and inorganic compounds will be considered. Surface protection: in this case, innovative composites will be developed consisting of polymers and nano-fillers. The use of hydrophobins, nano-assembled hydrofobic proteins extracted from fungi, and photocatalytic nano-particles (for favoring the decomposition of volatile organic molecules carried by polluted atmosphere and to prevent biofilm growth) will be considered. The project will contribute to the development of transnational cultural tourism and to the development of common European shared values and heritage, thus stimulating a greater sense of European identity.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FETPROACT-01-2016 | Award Amount: 7.98M | Year: 2017
A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (expected efficiency > 12%); ultra-thin layers and nanoparticles of metal or metal oxide catalysts for both half-cell reactions (expected efficiency > 90%); and stateof- the-art membrane technology for gas/liquid/products separation to match a theoretical target solar to fuels efficiency above 10%. All parts will be assembled to maximize performance in pH > 7 solution and moderate temperatures (50-80 C) as to take advantage of the high stability and favorable kinetics of constituent materials in these conditions. Achieving this goal we will improve the state-of-the-art of all components for the sake of cell integration: 1) Surface sciences: metal and metal oxide catalysts (crystals or nanostructures grown on metals or silicon) will be characterized for water oxidation and CO2 reduction through atomically resolved experiments (scanning probe microscopy) and spatially-averaged surface techniques including surface analysis before, after and in operando electrochemical reactions. Activity and performance will be correlated to composition, thickness, structure and support as to determine the optimum parameters for device integration. 2) Photoelectrodes: This unique surface knowledge will be transferred to the processing of catalytic nanostructures deposited on semiconductors through different methods to match the surface chemistry results through viable up-scaling processes. Multiple thermodynamic and kinetic techniques will be used to characterize and optimize the performance of the interfaces with spectroscopy and photo-electrochemistry tools to identify best matching between light absorbers and chemical catalysts along optimum working conditions (pH, temperature, pressure). 3) Modeling: Materials, catalysts and processes will be modeled with computational methods as a pivotal tool to understand and to bring photo-catalytic-electrodes to their theoretical limits in terms of performance. The selected optimum materials and environmental conditions as defined from these parallel studies will be integrated into a PEC cell prototype. This design will include ion exchange membranes and gas diffusion electrodes for product separation. Performance will be validated in real working conditions under sun irradiation to assess the technological and industrial relevance of our A-LEAF cell.
Agency: European Commission | Branch: H2020 | Program: ECSEL-IA | Phase: ECSEL-02-2014 | Award Amount: 8.18M | Year: 2015
R2POWER300 is committed to challenge the following Objectives: Development and manufacturing of a multi-KET Pilot Line (i.e. Nanoelectronics, Nanotechnology, Advanced Manufacturing) Energy Efficiency and CO2 Reduction megatrends. The project aims to achieve the following Goals: 1. Set the stage for the future extension to 300mm of the R2 Fab facility located in Agrate Brianza (Italy) - i.e. lines specification, tools evaluation and screening, new processs optimization and characterization, etc. 2. To evaluate, characterize and optimize the equipments and process necessary to achieve the new BCD10 technology, featuring 90nm lithography, at 300mm wafer size. BCD (i.e. Bipolar \ CMOS \ DMOS) is a unique smart power technology invented by ST in the mid 80s (CMOSs gate length was 4 m at that time!). As of today BCD is one of the key technology assets of ST and the indefatigable evolution and challenging roadmap makes ST a world-class leader on smart power ICs. 3. Advanced System in Packages: some SiP activity will be performed, with specific reference to Sintering based die-attach, thermal analysis and dedicated packaging solution for high density ALD capacitors.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: COMPET-06-2014 | Award Amount: 1.04M | Year: 2015
The project aims to realize a strong methodology for the development and design of a radiation hard non-volatile memory technology by using standard CMOS silicon processing. Since standard silicon memories, such as flash memories tend to fail under irradiation, a new approach is envisaged: the development of a specific memory technology, so called resistive random-access memory (RRAM), which is able to sustain heavy ions and other charged particles. The switching effect of RRAM devices is caused by chemical Redox-reactions, therefore, radiation effects like total ionizing dose and single event effects dont affect the switching mechanism. Semiconductor memories, among rad hard integrated circuit scenario, are one of the most critical topics for space applications. Actually both volatile and nonvolatile memories, excluding few exceptions, are integrated using standard processes and standard architectures. This means that the final device is typically at least Rad tolerant and not Rad Hard and failure during mission is avoided using Error Correcting Code techniques including redundancy at the board level. The basic goal of the project is to give a methodology for the development of a new rad-hard nonvolatile RRAM memory with high-performance features like good retention, re-programmability and cycling, and realize a prototype (1Mbit RRAM memory) in order to validate the approach.