Yang L.,Tianjin University |
Zhang-Negrerie D.,Concordia International School Shanghai |
Zhao K.,Tianjin University |
Du Y.,Tianjin University
Journal of Organic Chemistry | Year: 2016
Functionalization at the benzylic methylene group that is adjacent to the ring nitrogen atom in a series of N-aryltetrahydroisoquinoline compounds has been realized through intramolecular cross-dehydrogenative coupling reactions. The presented transformation provided straightforward access to the formation of C(sp3)-Y (Y = C, N or O) bond via I(III) reagent. © 2016 American Chemical Society.