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Yang L.,Tianjin University | Zhang-Negrerie D.,Concordia International School Shanghai | Zhao K.,Tianjin University | Du Y.,Tianjin University
Journal of Organic Chemistry | Year: 2016

Functionalization at the benzylic methylene group that is adjacent to the ring nitrogen atom in a series of N-aryltetrahydroisoquinoline compounds has been realized through intramolecular cross-dehydrogenative coupling reactions. The presented transformation provided straightforward access to the formation of C(sp3)-Y (Y = C, N or O) bond via I(III) reagent. © 2016 American Chemical Society.

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