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Moorhead, MN, United States

Concordia College is a private college located in Moorhead, Minnesota, United States. Founded by Norwegian settlers in 1891, the school is associated with the Evangelical Lutheran Church in America and practices the liberal arts. Concordia is accredited by The Higher Learning Commission and has a total student enrollment of 2,531. It offers Bachelor of Arts, Bachelor of Music, and Master of Education degrees.Since Concordia was founded, it has articulated a Christian and global curriculum. Students are required to take courses in health, communication, religion, and culture. The university maintains athletic teams in 22 sports and carries 19 music ensembles, including The Concordia Choir and The Concordia Band. Wikipedia.


Jensen M.B.,Concordia College
Journal of Chemical Education | Year: 2015

An instrumentation-based laboratory curriculum combining traditional unknown analyses with student-designed projects has been developed for an introductory analytical chemistry course. In the first half of the course, students develop laboratory skills and instrumental proficiency by rotating through six different instruments performing quantitative analyses of unknowns. In the second half of the course, students use these skills to design and perform a quantitative chemical analysis of a real-world sample of their choosing in which students direct each step in the analytical process: sampling, sample preparation, data acquisition, interpretation, reporting, and drawing conclusions. Unique features of the course include open lab periods, an online lab manual with embedded video demonstrations, and the publication of student projects in an online journal. Assessment results show that students report high levels of gain in relation to the desired outcomes of the overall project. © 2014 The American Chemical Society and Division of Chemical Education, Inc. Source


Axvig N.,Concordia College
IEEE Transactions on Information Theory | Year: 2014

An approximation of maximum-likelihood decoding over the binary symmetric channel was introduced by Omura in 1972. This decoder employs an iterative, randomized algorithm whose behavior closely mimics that of the simplex algorithm. In this paper, we generalize Omura's decoder to operate on an arbitrary binary-input memoryless channel. Further, we prove that the probability of the generalized Omura decoder (and hence Omura's original decoder) returning a maximum-likelihood codeword approaches 1 as the number of iterations goes to infinity, a result that has hereto remained unproven. © 1963-2012 IEEE. Source


Calcada M.,State University of Ponta Grossa | Lunardi J.T.,State University of Ponta Grossa | Manzoni L.A.,Concordia College | Monteiro W.,State University of Ponta Grossa
Frontiers of Physics | Year: 2014

We consider the one-dimensional quantum mechanical problem of defining interactions concentrated at a single point in the framework of the theory of distributions. The often ill-defined product which describes the interaction term in the Schrödinger and Dirac equations is replaced by a well-defined distribution satisfying some simple mathematical conditions and, in addition, the physical requirement of probability current conservation is imposed. A four-parameter family of interactions thus emerges as the most general point interaction both in the non-relativistic and in the relativistic theories (in agreement with results obtained by self-adjoint extensions). Since the interaction is given explicitly, the distributional method allows one to carry out symmetry investigations in a simple way, and it proves to be useful to clarify some ambiguities related to the so-called δ′ interaction. © 2014 Calçada, Lunardi, Manzoni and Monteiro. Source


Veldhoen R.A.,University of Alberta | Banman S.L.,University of Alberta | Hemmerling D.R.,Concordia College | Odsen R.,University of Alberta | And 4 more authors.
Oncogene | Year: 2013

Anti-mitotic agents such as paclitaxel and docetaxel are widely used for the treatment of breast, ovarian and lung cancers. Although paclitaxel induces apoptosis, this drug also modulates autophagy. How autophagy affects paclitaxel activity, is unclear. We discovered that paclitaxel inhibited autophagy through two distinct mechanisms dependent on cell cycle stage. In mitotic cells, paclitaxel blocked activation of the class III phosphatidyl inositol 3 kinase, Vps34, a critical initiator of autophagosome formation. In non-mitotic paclitaxel-treated cells, autophagosomes were generated but their movement and maturation was inhibited. Chemically or genetically blocking autophagosome formation diminished paclitaxel-induced cell death suggesting that autophagosome accumulation sensitized cells to paclitaxel toxicity. In line with these observations, we identified that primary breast tumors that expressed diminished levels of autophagy-initiating genes were resistant to taxane therapy, identifying possible mechanisms and prognostic markers of clinical chemotherapeutic resistance. © 2013 Macmillan Publishers Limited All rights reserved. Source


Askvig J.M.,Concordia College | Watt J.A.,University of North Dakota
Journal of Cell Communication and Signaling | Year: 2015

While collateral sprouting has been shown to occur in a variety of neuronal populations, the factor or factors responsible for mediating the sprouting response remain largely un-defined. There is evidence indicating that ciliary neurotrophic factor (CNTF) may play an important role in promoting neuronal survival and process outgrowth in neuronal phenotypes tested to date. We previously demonstrated that the astrocytic Jak-STAT pathway is necessary to mediate CNTF-induced oxytocinergic (OT) neuronal survival; however, the mechanism (s) of CNTF-mediated process outgrowth remain unknown. Our working hypothesis is that CNTF mediates differential neuroprotective responses via different intracellular signal transduction pathways. In order to test this hypothesis, we utilized stationary hypothalamic organotypic cultures to assess the contribution of the MAPK-ERK and PI3-AKT pathways to OT neuron survival and process outgrowth. Our results demonstrate that the MAPK-ERK½ pathway mediates CNTF-induced neuronal survival. Moreover, we show that inhibition of the p38-, JNK-MAPK, and mTOR pathways prevents loss OT neurons following axotomy. We also provide quantitative evidence indicating that CNTF promotes process outgrowth of OT neurons via the PI3K-AKT pathway. Together, these data indicate that distinct intracellular signaling pathways mediate diverse neuroprotective processes in response to CNTF. © 2015, The Author(s). Source

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