Racca P.,SSCVD Colorectal Cancer Unit |
Spadi R.,SSCVD Colorectal Cancer Unit |
Fora G.,SSCVD Colorectal Cancer Unit |
Fanchini L.,SSCVD Colorectal Cancer Unit |
And 5 more authors.
Tumori | Year: 2011
Introduction. Oxaliplatin is a third-generation platinum compound with proven antitumor activity in the treatment of colorectal cancer. The occurrence of life-threating hemolitic uremic syndrome has been observed after oxaliplatin therapy. The kind of tumor and treatmentmodalities seemto influence the onset of hemolitic uremic syndrome. Methods. The clinical course of the case is reviewed and compared with reports of other similar cases in the literature. Results. We describe the development of hemolitic uremic syndrome as a result of prolonged oxaliplatin treatment of a colon cancer patient. Conclusions. Although this rare event requires the concurrence of other unknown factors, it should be considered in a decision-making setting.