Cocuk Saglg ve Hastalklar Anabilim Dal

Bursa, Turkey

Cocuk Saglg ve Hastalklar Anabilim Dal

Bursa, Turkey

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Goksugur S.B.,Cocuk Saglg ve Hastalklar Anabilim Dal | Bekdas M.,Cocuk Saglg ve Hastalklar Anabilim Dal | Isk C.,Ortopedi ve Travmatoloji Anabilim Dal | Sarac E.G.,Cocuk Saglg ve Hastalklar Anabilim Dal | Demircioglu F.,Cocuk Hematolojisi Bilim Dal
Cocuk Enfeksiyon Dergisi | Year: 2015

Varicella is generally a benign infectious disease; however, it can causes complications, such as secondary bacterial infections of the skin and soft tissues, pneumonia, and hematological and neurological complications. Also, it can be rarely complicated with septic arthritis. Here, in this article, a 3.5-year-old boy who developed swelling, erythema, and pain at the right wrist and right knee 5 days after varicella, diagnosed as septic arthritis based on synovial fluid investigation and radiological imaging, is reported. ©Telif Hakkı 2015 Çocuk Enfeksiyon Hastalıkları Derneği - Makale metnine.


Evim M.S.,Cocuk Hematoloji Bilim Dal | Tuten R.,Cocuk Saglg ve Hastalklar Anabilim Dal | Baytan B.,Cocuk Hematoloji Bilim Dal | Yakarsk S.,Cocuk Hematoloji Bilim Dal | Gunes A.M.,Cocuk Hematoloji Bilim Dal
Guncel Pediatri | Year: 2014

Vitamin B12 is essential to all cells in the body. Both high levels and low levels of vitamin B12 are significant. High serum cobalamin (vitamin B12) levels are found particularly in hematological disorders, solid tumors, autoimmune diseases, renal diseases and infectious diseases; and this elevation is associated with prognosis in some of these diseases. High levels of serum vitamin B12 should be taken into consideration and more studies should be performed on this issue. © The Journal of Current Pediatrics, published by Galenos Publishing.


Yetim A.,Cocuk Saglg ve Hastalklar Anabilim Dal | Yetim C.,Krkhan Devlet Hastanesi | Devecioglu E.,Cocuk Saglg ve Hastalklar Anabilim Dal
Guncel Pediatri | Year: 2015

Introduction: Errors in complementary feeding may lead to important problems in child’s physical and mental development. In this study, we aimed to investigate feeding practices, attitudes and knowledge of mothers with infants aged 20-36 months, who attended the outpatient departments. Materials and Methods: Research was performed in the center of Iğdır and the town of Iğdır called Tuzluca. Two hundred three mothers with children aged 20 to 36 months that attended Iğdır and Tuzluca State Hospitals between June-July 2012 constituted the study population. A questionnaire consisting of 11 questions was administered. Questions were asked in detail by a physician. Results: Seventy percent of mothers had breastfed their babies within 1 hour after birth, 92% within 1-24 hours. All mothers thought that breastfeeding was the best for their babies. The mean duration of breastfeeding was 17.0±8.0 months, complementary feeding was started at 6.4 months. Twenty two mothers began to give complementary foods to their babies before 6 months, 51% at 6 months, 15.7% between 6-9 months, and 11% at 9 months and later. The first choice as a complementary food was homemade yogurt (67%) and the second was yoghurt from market (47%). Vegetables and fruit puree were not among the first choices of complementary foods. Sixty three percent of mothers received information from people around (mother, mother-in-law, sister-inlaw, neighbor, etc.), 31% of from health personnel in the family health centers. Conclusions: Mothers in Iğdır and Tuzluca seemed to need counseling about complementary feeding. Health workers with current and practical knowledge should give accurate information to mothers. © The Journal of Current Pediatrics, published by Galenos Publishing.


Balc O.,Cocuk Saglg ve Hastalklar Anabilim Dal | Iskay S.,Gaziantep Cocuk Hastanesi
Guncel Pediatri | Year: 2014

A few infections called with an acronym as TORCH may cause abortion, premature birth or congenital anomalies if acquired during the pregnancy. ORCH, as an acronym, stands for toxoplasmosis, other (syphilis, tuberculosis, listeria, candidiasis, parvovirus B19, varicella, HIV, hepatitis B, coxiella burnetii), rubellavirus, cytomegalovirus (CMV), and herpes simplex virus (HSV). Here, we present toxoplasma infection as a rare reason of neonatal hydrocephalus. © The Journal of Current Pediatrics, published by Galenos Publishing.


Balc O.,Cocuk Saglg ve Hastalklar Anabilim Dal | Iskay S.,Gaziantep Cocuk Hastanesi | Varan C.,Cocuk Saglg ve Hastalklar Anabilim Dal | Klnc A.M.,Cocuk Saglg ve Hastalklar Anabilim Dal | Almacoglu M.,Cocuk Saglg ve Hastalklar Anabilim Dal
Guncel Pediatri | Year: 2015

Urticaria is mainly a fast consisting, scabious, erythematous and swelling lesions of the skin. Acute urticaria usually occurs after having a medicine or food. On the other hand, in the chronic urticaria, the process is longer, more scabious, and the skin lesions are more dramatic. In urticarial vasculitis, the lesions exist longer than 24 hours with pain or swelter instead of itchiness. It can be distinguished from basic urticaria with the damage of the small vessels by histopathologically. Here we present two normocomplementhemic urticarial vasculitis cases. © The Journal of Current Pediatrics, published by Galenos Publishing.


Temur E.,Cocuk Saglg ve Hastalklar Anabilim Dal | Dinleyici E.C.,Cocuk Saglg ve Hastalklar Anabilim Dal | Tekin R.T.,Cocuk Saglg ve Hastalklar Anabilim Dal | Kiremitci A.,Mikrobiyoloji Anabilim Dal | And 5 more authors.
Cocuk Enfeksiyon Dergisi | Year: 2015

Objective: Incidence of Acinetobacter infections is increasing both in Turkey and worldwide. Based on their ability to develop resistance, Acinetobacter species can cause morbidity and mortality, particularly in newborns, children, immunocompromised patients, and critically ill intensive care patients. There are limited treatment options, particularly in carbapenem resistant Acinetobacter strains. In this study, we aimed to compare in vivo activities of colistin sulphate, tigecycline, and cefoperazone-sulbactam in an experimental mouse sepsis model. Material and Methods: Each of the four study groups consisted of eight Wistar breed albino rats. In total, 107 colonies of the Acinetobacter baumannii/calcoaceticus complex were administered intraperitoneally to each rat after the presence of neutropenia with cyclophosphamide. Blood culture samples were taken from all rats after 24 h of treatment and colony count from lung, liver, and kidney specimens were taken after 72 h of treatment. Results: In the tigecycline-treated group, the presence of positive blood culture results at 24 h were found to be lower than the control group (p=0.01). Presence of positive cultures from lung samples in the tigecycline (p<0.05), colistin (p<0.05), and cefoperazone-sulbactam (p<0.05) groups were found to be lower than the control group. Positive culture of liver samples were found to be significantly lower in colistin (p<0.05) and cefoperazone-sulbactam (p<0.05) groups than the control. Positive culture of kidney samples were found to be significantly lower in colistin (p<0.05), cefoperazone-sulbactam (p<0.05), and tigecycline (p<0.05) groups than the control. However, antibiotic groups did not differ among themselves with respect to positive culture. A comparison of colony counts in lung samples revealed a statistically significant decrease in tigecycline and colistin groups than the control group (p<0.01 and p<0.05, respectively). Conclusion: In our study, tigecycline, colistin, and cefoperazone-sulbactam were found to be effective on culture positivity in lung, kidney, and liver specimens of rats and they may be a choice for treatment. Tigecycline was found to be more effective on colony counts in lungs and kidneys and is also more effective in reducing the 24 h bacteraemia than the control group. The results of the ongoing clinical trials about tigecycline use in children with severe infection due to resistant microorganisms will give us an idea about this situation. ©Telif Hakkı 2015 Çocuk Enfeksiyon Hastalıkları Derneği - Makale metnine.


Uner G.,Cocuk Saglg ve Hastalklar Anabilim Dal | Cekic S.,Cocuk Saglg ve Hastalklar Anabilim Dal | Gultekin S.S.K.,Cocuk Saglg ve Hastalklar Anabilim Dal
Guncel Pediatri | Year: 2014

Hyperimmunoglobulin M syndrome is a primary immune deficiency characterized by increased or normal levels of serum IgM with clearly decreased serum IgG, IgA and IgE levels. Patients affected with hiper IgM syndrome are susceptible to recurrent pyogenic infections, to autoimmune diseases induced by IgM antibodies and to malignant lymphoproliferative disease IgM producing B cells. Intravenous immunoglobulin replacement for therapy every 3-4 weeks is effective. Prophylactic treatment for P. jirovecii on trimethoprim-sulfhamethoxazole, in selected neutropenic patients granulocyte colony stimulated factor (G-CSF) treatment is suggested. Bone marrow or cord blood transplantation may provide cure for this syndrome. © The Journal of Current Pediatrics, published by Galenos Publishing.


Aslan A.,Cocuk Saglg ve Hastalklar Anabilim Dal | Kurugol Z.,Cocuk Saglg ve Hastalklar Anabilim Dal | Koturoglu G.,Cocuk Saglg ve Hastalklar Anabilim Dal
Cocuk Enfeksiyon Dergisi | Year: 2014

Erythema nodosum is a self-limited, autoimmune inflammatory disease of subcutaneous tissue. It is rarely seen in childhood. Erythema nodosum may occur as an isolated condition or in association with infectious (streptococcal pharyngitis, tuberculosis, Epstein-Barr virus infection, fungal infection) and non-infectious conditions (sarcoidosis, inflammatory bowel disease, connective tissue diseases, antibiotics, malignancies). Erythema nodosum associated with mycoplasma infection is uncommon. We report here the case of a 10-year-old patient with erythema nodosum associated with Mycoplasma pneumoniae infection. The patient had no symptoms of the respiratory system. © 2014 by Pediatric Infectious Diseases Society.


Demir S.O.,Cocuk Saglg ve Hastalklar Anabilim Dal | Kadayfc E.K.,Cocuk Saglg ve Hastalklar Anabilim Dal | Karaaslan A.,Cocuk Saglg ve Hastalklar Anabilim Dal | Atc S.,Cocuk Saglg ve Hastalklar Anabilim Dal | And 7 more authors.
Cocuk Enfeksiyon Dergisi | Year: 2015

Objective: Varicella and herpes zoster are infectious diseases caused by varicella-zoster virus (VZV) and are generally not serious diseases in immunocompetent patients. However, patients with impaired cellular immunity because of chemotherapy, immune suppressive agent, HIV infection, and primary immune deficiency syndromes have tendency toward causing infections with VZV; also, VZV infections may be more severe with complications in these patient groups. Acyclovir is the drug of choice for treatment of both illnesses. Herein, we aim to describe the characteristics of VZV infections and the role of acyclovir in the treatment of immunocompromised children for these infections. Materials and Methods: Thirty-three children with primary or secondary immune deficiency syndromes aged less than 18 years who were admitted to the Pediatrics clinic of Marmara University Medical Faculty Hospital for varicella or herpes zoster infections between January 2012 and June 2015 were enrolled in this study. Data about clinical manifestations, treatment, and prognosis of VZV infections are collected by performing a chart review of these patients. Results: Thirty-three patients enrolled into the study were aged between 6 months and 16 years with the mean age of 96±52 months. The reasons for causing immune suppression were solid tumor in 15 patients, ALL in 7, primary immune deficiency in 5, immune suppressive drug usage in 3, HIV in 1, organ transplantation in 2 patients. Seven patients were treated for herpes zoster and 16 for varicella. Acyclovir was administered with a dosage of 1500 mg/m2/day divided in three intravenous doses in the first 72 hours of disease manifestations, and the mean duration of treatment was 7 days (range 3–11). Vesicular rash begun to be crusted at 3. Day of treatment and completely crusted at 5th day in all patients. No complications of infection or drug-related adverse effects were observed. Conclusion: This study showed that acyclovir is still safe and is an effective agent for VZV infections; particularly, to prevent complications and dissemination of infection in immunocompromised children, acyclovir administration should be initiated immediately. © 2015 by Pediatric Infectious Diseases Society.


Cekic S.,Cocuk Saglg ve Hastalklar Anabilim Dal | Sapan N.,Cocuk Saglg ve Hastalklar Anabilim Dal
Guncel Pediatri | Year: 2015

Allergen specific immunotherapy (SIT) is the only treatment that can provide a cure for allergic disorders. This treatment is based on development of immune tolerance by exposure to allergen in repetitive and increasing doses. It is tertiary to avoidance of allergen and pharmacotherapy. Allergens used for immunotherapy, must be confirmed by skin prick test or specific IgE and must be applied in supervision of allergy specialists. Studies show that immunotherapy, improve asthma symptoms, decreases drug consumption, prevent development of asthma in rhinitis patients and reduce new sensitizations. Common side effects diminished with the usage of standardized allergen solutions. It is contraindicated in severe asthma. Though it is recommended to avoid immunotherapy in patients using beta blockers and ACE inhibitors, immunotherapy can be considered in mandatory situations regarding possible benefits and harms. Most common ways of administration are subcutaneous and sublingual; new methods such as epicutaneous and intralymphatic injections are currently being studied. © The Journal of Current Pediatrics, published by Galenos Publishing.

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