Time filter

Source Type

Mourer-Chauvire C.,CNRS Geological Laboratory of Lyon: earth, planets and environment
Neues Jahrbuch fur Geologie und Palaontologie - Abhandlungen | Year: 2013

The genus Dynamopterus Milne-edwards, 1892, described from the "Phosphorites du Quercy", is only known from humeri, whereas the genus Idiornis OberhOlser, 1899, is known in the Quercy from numerous elements of the post-cranial skeleton, but its humeri are known only from three fragments referred to the species I. itardiensis. Comparison of the humeri of Dynamopterus with those of Idiornis itardiensis, and with the recent genus Cariama, makes it possible to identify these humeri as belonging to the same genus as the remains attributed to Idiornis. The generic name Dynamopterus Milne-edwards, 1892, has priority over Idiornis OberhOlser, 1899, and therefore must replace it. © 2013 E. Schweizerbart'sche Verlagsbuchhandlung, Stuttgart, Germany. Source

Legg D.A.,Imperial College London | Legg D.A.,Natural History Museum in London | Vannier J.,CNRS Geological Laboratory of Lyon: earth, planets and environment
Lethaia | Year: 2013

Isoxys is a cosmopolitan bivalved arthropod genus known almost exclusively from Cambrian Konservat-Lagerstätten. Despite its wide geographical distribution in such sites of exceptional preservation, little was known of its soft-part anatomy until recently when remains of eyes and raptorial frontal appendages were discovered. This absence has precluded determination of affinities. The new discovery of soft parts led to two important hypotheses: (1) that Isoxys was related to the 'great-appendage' arthropods and (2) that its contained species were not congeneric. Neither has been tested using a detailed cladistics analysis. The morphology of Isoxys is re-evaluated and coded into an extensive cladistics analysis. Our results indicate that Isoxys was indeed a monophyletic genus with all representatives united by the presence of an expansive dorsal shield with prominent antero- and posterolateral cardinal spines. It also indicates that Isoxys occupies a crucial role in arthropod evolution, resolving at the base of Arthropoda. The 'great appendages' of Isoxys are interpreted as innovating from either the protocerebral or deutocerebral somite and are therefore not homologous to those of other 'great-appendage' arthropods, which are interpreted as originating from the tritocerebral somite of the head. © 2013 The Lethaia Foundation. Source

Buffetaut E.,CNRS ENS Geology Laboratory | Angst D.,CNRS Geological Laboratory of Lyon: earth, planets and environment
Geological Magazine | Year: 2013

A large heterocoelous cervical vertebra from the Late Cretaceous of Cruzy (Hérault, southern France) is described and referred to the giant bird Gargantuavis philoinos Buffetaut & Le Loeuff, 1998, confirming its avian nature. Gargantuavis appears to have been a long-necked bird with possibly a relatively small skull. Derived features such as heterocoely suggest that Gargantuavis was an advanced ornithuromorph, close to ornithurines. Copyright © 2012 Cambridge University Press. Source

Bonaventura P.,University of Lyon | Benedetti G.,University of Lyon | Albarede F.,CNRS Geological Laboratory of Lyon: earth, planets and environment | Miossec P.,University of Lyon
Autoimmunity Reviews | Year: 2015

Zinc (Zn) nutritional importance has been known for a long time, but in the last decades its importance in immune modulation has arisen. This review aims at describing the mechanisms involved in the regulation of Zn homeostasis and their effects on the immune response focusing on those which are implicated in the physiopathology of rheumatoid arthritis. Zn functions as a modulator of the immune response through its availability, which is tightly regulated by several transporters and regulators. When this mechanism is disturbed, Zn availability is reduced, altering survival, proliferation and differentiation of the cells of different organs and systems and, in particular, cells of the immune system. Zn deficiency affects cells involved in both innate and adaptive immunity at the survival, proliferation and maturation levels. These cells include monocytes, polymorphonuclear-, natural killer-, T-, and B-cells. T cell functions and the balance between the different T helper cell subsets are particularly susceptible to changes in Zn status. While acute Zn deficiency causes a decrease in innate and adaptive immunity, chronic deficiency increases inflammation. During chronic deficiency, the production of pro-inflammatory cytokines increases, influencing the outcome of a large number of inflammatory diseases, including rheumatoid arthritis. © 2014 Elsevier B.V. Source

Vannier J.,CNRS Geological Laboratory of Lyon: earth, planets and environment | Liu J.,Northwest University, China | Lerosey-Aubril R.,CNRS Geological Laboratory of Lyon: earth, planets and environment | Vinther J.,University of Bristol | Daley A.C.,University of Oxford
Nature Communications | Year: 2014

Understanding the way in which animals diversified and radiated during their early evolutionary history remains one of the most captivating of scientific challenges. Integral to this is the 'Cambrian explosion', which records the rapid emergence of most animal phyla, and for which the triggering and accelerating factors, whether environmental or biological, are still unclear. Here we describe exceptionally well-preserved complex digestive organs in early arthropods from the early Cambrian of China and Greenland with functional similarities to certain modern crustaceans and trace these structures through the early evolutionary lineage of fossil arthropods. These digestive structures are assumed to have allowed for more efficient digestion and metabolism, promoting carnivory and macrophagy in early arthropods via predation or scavenging. This key innovation may have been of critical importance in the radiation and ecological success of Arthropoda, which has been the most diverse and abundant invertebrate phylum since the Cambrian. © 2014 Macmillan Publishers Limited. Source

Discover hidden collaborations