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Nivelles, Belgium

Deltour D.,Clinique Notre Dame de Grace | Veys E.,Clinique Notre Dame de Grace
Acta Chirurgica Belgica | Year: 2011

Tailgut cysts, also called retro-rectal cystic hamartomas or mucin-secreting cysts, are uncommon vestigial masses. They can become complicated with infection or neoplastic degeneration. Surgery is the only treatment. We report here a case of a tailgut cyst in a 60-year-old female, that was discovered 10 years ago but not investigated. Source

Goudetsidis L.,Clinique Notre Dame de Grace | Titeca G.,Clinique Notre Dame de Grace | Poot F.,Clinique Notre Dame de Grace
Revue Medicale de Bruxelles | Year: 2015

Introduction: Orofacial granulomatosis represents a group of pathologies characterized by a granulomatous inflammation of the face and the oral mucosa. Its etiology is unknown. Since the macrocheilitis resulting from an inflammation could be associated to different pathologies, an accurate diagnosis has to be established. Observation: A 74-year old woman developed a swelling of the inferior lip spreading towards the chin. No lesions was present on the oral mucosa. No other symptoms were reported. The biopsy and further exams concluded to an idiopathic orofacial granulomatosis. Triamcinolone 10 mg/ml was used as treatment and has allowed a lasting improvement of the swelling. Discussion: This rare observation, especially with an older patient, has allowed to illustrate the importance of an accurate diagnosis when facing a macrocheilitis. Indeed, macrocheilitis can be associated to pathologies such as Crohn disease, sarcoidosis or tuberculosis, requiring an appropriate care. Source

Delefortrie Q.,Clinique Notre Dame de Grace | Schatt P.,Clinique Notre Dame de Grace | Grimmelprez A.,Clinique Notre Dame de Grace | Gohy P.,Clinique Notre Dame de Grace | And 3 more authors.
Clinical Biochemistry | Year: 2016

Background: Although colonoscopy associated with histopathological sampling remains the gold standard in the diagnostic and follow-up of inflammatory bowel disease (IBD), calprotectin is becoming an essential biomarker in gastroenterology. The aim of this work is to compare a newly developed kit (Liaison® Calprotectin - Diasorin®) and its two distinct extraction protocols (weighing and extraction device protocol) with a well established point of care test (Quantum Blue® - Bühlmann-Alere®) in terms of analytical performances and ability to detect relapses amongst a Crohn's population in follow-up. Methods: Stool specimens were collected over a six month period and were composed of control and Crohn's patients. Amongst the Crohn's population disease activity (active vs quiescent) was evaluated by gastroenterologists. Results: A significant difference was found between all three procedures in terms of calprotectin measurements (weighing protocol = 30.3 μg/g (median); stool extraction device protocol = 36.9 μg/g (median); Quantum Blue® (median) = 63; Friedman test, P value = 0.05). However, a good correlation was found between both extraction methods coupled with the Liaison® analyzer and between the Quantum Blue® (weighing protocol/extraction device protocol Rs = 0.844, P = 0.01; Quantum Blue®/extraction device protocol Rs = 0.708, P = 0.01; Quantum Blue®/weighing protocol, Rs = 0.808, P = 0.01). Finally, optimal cut-offs (and associated negative predictive values - NPV) for detecting relapses were in accordance with above results (Quantum Blue® 183.5 μg/g and NPV of 100% > extraction device protocol + Liaison® analyzer 124.5 μg/g and NPV of 93.5% > weighing protocol + Liaison® analyzer 106.5 μg/g and NPV of 95%). Conclusions: Although all three methods correlated well and had relatively good NPV in terms of detecting relapses amongst a Crohn's population in follow-up, the lack of any international standard is the origin of different optimal cut-offs between the three procedures. © 2015 The Canadian Society of Clinical Chemists. Source

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