Clinic of Laser Plastics

Riga, Latvia

Clinic of Laser Plastics

Riga, Latvia
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Bekina A.,University of Latvia | Garancis V.,Telemedica SIA | Rubins U.,University of Latvia | Spigulis J.,University of Latvia | And 2 more authors.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Year: 2013

A variety of multi-spectral imaging devices is commercially available and used for skin diagnostics and monitoring; however, an alternative cost-efficient device can provide an advanced spectral analysis of skin. A compact multimodal device for diagnosis of pigmented skin lesions was developed and tested. A polarized LED light source illuminates the skin surface at four different wavelengths - blue (450 nm), green (545 nm), red (660 nm) and infrared (940 nm). Spectra of reflected light from the 25 mm wide skin spot are imaged by a CMOS sensor. Four spectral images are obtained for mapping of the main skin chromophores. The specific chromophore distribution differences between different skin malformations were analyzed and information of subcutaneous structures was consecutively extracted. © 2013 SPIE.


Rubins U.,University of Latvia | Spigulis J.,University of Latvia | Valeine L.,Altera | Berzina A.,Clinic of Laser Plastics
Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Year: 2013

The multi-spectral imaging technique to reveal skin malformations has been described in this work. Four spectral images taken at polarized monochromatic LED illumination (450nm, 545nm, 660nm and 940 nm) and polarized white LED light imaged by CMOS sensor via cross-oriented polarizing filter were analyzed to calculate chromophore maps. The algorithm based on skin color analysis and user-defined threshold selection allows highlighting of skin areas with predefined chromophore concentration semi-automatically. Preliminary results of clinical tests are presented.© 2013 OSA-SPIE.


Jakovels D.,University of Latvia | Kuzmina I.,University of Latvia | Berzina A.,Clinic of Laser Plastics | Spigulis J.,University of Latvia
Biomedical Optics, BIOMED 2012 | Year: 2012

RGB imaging system for mapping and monitoring of hemoglobin changes in skin has been tested for evaluation of vascular malformations' laser treatment. The multi-spectral imaging system was used as the reference. © OSA 2012.


Kuzmina I.,University of Latvia | Lacis M.,University of Latvia | Spigulis J.,University of Latvia | Berzina A.,Clinic of Laser Plastics | Valeine L.,Beauty Clinic 4th Dimension
Journal of Biomedical Optics | Year: 2015

RGB (red-green-blue) technique for mapping skin chromophores by smartphones is proposed and studied. Three smartphones of different manufacturers were tested on skin phantoms and in vivo on benign skin lesions using a specially designed light source for illumination. Hemoglobin and melanin indices obtained by these smartphones showed differences in both tests. In vitro tests showed an increment of hemoglobin and melanin indices with the concentration of chromophores in phantoms. In vivo tests indicated higher hemoglobin index in hemangiomas than in nevi and healthy skin, and nevi showed higher melanin index compared to the healthy skin. Smartphones that allow switching off the automatic camera settings provided useful data, while those with "embedded" automatic settings appear to be useless for distant skin chromophore mapping. © 2015 Society of Photo-Optical Instrumentation Engineers (SPIE).


Jakovels D.,University of Latvia | Kuzmina I.,University of Latvia | Berzina A.,Clinic of Laser Plastics | Valeine L.,Beauty Clinic 4th Dimension | Spigulis J.,University of Latvia
Journal of Biomedical Optics | Year: 2013

A prototype low-cost RGB imaging system consisting of a commercial RGB CMOS sensor, RGB lightemitting diode ring light illuminator, and a set of polarizers was designed and tested for mapping the skin erythema index, in order to monitor skin recovery after phototherapy of vascular lesions, such as hemangiomas and telangiectasias. The contrast of erythema index (CEI) was proposed as a parameter for quantitative characterization of vascular lesions. Skin recovery was characterized as a decrease of the CEI value relative to the value before the treatment. This approach was clinically validated by examining 31 vascular lesions before and after phototherapy.© 2013 Society of Photo-Optical Instrumentation Engineers.


Kuzmina I.,University of Latvia | Diebele I.,University of Latvia | Jakovels D.,University of Latvia | Spigulis J.,University of Latvia | And 3 more authors.
Journal of Biomedical Optics | Year: 2011

A clinical trial comprising 334 pigmented and vascular lesions has been performed in three Riga clinics by means of multispectral imaging analysis. The imaging system Nuance 2.4 (CRi) and self-developed software for mapping of the main skin chromophores were used. Specific features were observed and analyzed for malignant skin melanomas: notably higher absorbance (especially as the difference of optical density relative to the healthy skin), uneven chromophore distribution over the lesion area, and the possibility to select the "melanoma areas" in the correlation graphs of chromophores. The obtained results indicate clinical potential of this technology for noncontact selection of melanoma from other pigmented and vascular skin lesions. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).


Kuzmina I.,University of Latvia | Diebele I.,University of Latvia | Spigulis J.,University of Latvia | Valeine L.,Beauty Clinic 4th Dimension | And 2 more authors.
Journal of Biomedical Optics | Year: 2011

Optical fiber contact probe diffuse reflectance spectroscopy and remote multispectral imaging methods in the spectral range of 400 to 1100 nm were used for skin vascular malformation assessment and recovery tracing after treatment by intense pulsed light. The results confirmed that oxy-hemoglobin relative changes and the optical density difference between lesion and healthy skin in the spectral region 500 to 600 nm may be successfully used for objective appraisal of the therapy effect. Color redness parameter a 2 is suggested as a diagnostic border to distinguish healthy skin and vascular lesions, and as the indicator of phototreatment efficiency. Valuable diagnostic information on large area (5 mm) lesions and lesions with uncertain borders can be proved by the multispectral imaging method. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).

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