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AlJaroudi W.A.,Clemenceau Medical Center | Hage F.G.,University of Alabama at Birmingham | Hage F.G.,Birmingham Veterans Affairs Medical Center
Journal of Nuclear Cardiology | Year: 2016

In 2015, many original articles pertaining to cardiovascular imaging with impressive quality were published in the Journal of Nuclear Cardiology. In a set of 2 articles, we provide an overview of these contributions to facilitate for the interested reader a quick review of the advancements that occurred in the field over this year. In this first article, we focus on arterial plaque imaging, cardiac positron emission tomography, computed tomography, and magnetic resonance imaging. © 2015, American Society of Nuclear Cardiology. Source

Andrikopoulou E.,University of Alabama at Birmingham | Andrikopoulou E.,Birmingham Veterans Affairs Medical Center | AlJaroudi W.A.,Clemenceau Medical Center | Farag A.,University of Alabama at Birmingham | And 5 more authors.
European Journal of Nuclear Medicine and Molecular Imaging | Year: 2016

Purpose: The heart rate response (HRR, percentage change from baseline) to regadenoson during myocardial perfusion imaging (MPI) can provide incremental prognostic value in patients with known or suspected coronary artery disease. Our purpose was to evaluate the variability and prognostic value of HRR on serial measurements. Methods: We studied 648 consecutive patients (61 ± 11 years, 48 % with diabetes) who underwent two regadenoson MPI studies (16 ± 9 months between studies). HRR <30 % was defined as abnormal. All-cause mortality was determined by chart review and verified using the US Social Security Death Master File. Results: HRR was well correlated between the two studies (intraclass correlation coefficient 0.72, 95 % CI 0.67 – 0.76) with no systematic bias (mean difference 0.88 %, p = 0.2) or proportional bias (p = 0.5) by Bland-Altman analysis in all patients and in those with normal MPI on both studies. Of the 308 patients (48 %) with normal baseline HRR (HRR-1), 33 % had developed a blunted HRR on the second MPI study (HRR-2). Older age, male gender, end-stage renal disease, and abnormal baseline left ventricular ejection fraction were independent predictors of a new-onset abnormal HRR. During a mean follow-up of 2.4 ± 1.2 years, 55 patients (8.5 %) died. Patients with a blunted HRR-1 had increased mortality risk irrespective of their HRR-2 (p = 0.9, log-rank test). Among patients with normal HRR-1, a blunted HRR-2 was an independent predictor of all-cause mortality beyond clinical and traditional MPI data (hazard ratio 2.83, 95 % CI 1.14 – 7.03). Finally, patients with a normal HRR-1 and HRR-2 had the lowest event rate, while those with any abnormal HRR had an increased risk of death (hazard ratio 2.5, 95 % CI 1.2 – 5.4). Conclusion: There was good correlation in the HRR to regadenoson on serial measurements without systematic or proportional biases. Patients with consistently normal HRR had the best prognosis. © 2016, Springer-Verlag Berlin Heidelberg. Source

Hage F.G.,University of Birmingham | Hage F.G.,Birmingham Veterans Affairs Medical Center | AlJaroudi W.A.,Clemenceau Medical Center
Journal of Nuclear Cardiology | Year: 2016

In 2015, the Journal of Nuclear Cardiology® published many high-quality articles. In this series, we will summarize key articles that have appeared in the Journal last year to provide for the interested reader a quick review of the advancements that have recently occurred in the field. In the first article of this 2-part series, we concentrated on publications dealing with plaque imaging, cardiac positron emission tomography, computed tomography, and magnetic resonance. This review will focus on myocardial perfusion imaging summarizing advances in the field including in diagnosis, prognosis, and appropriate use. © 2016, American Society of Nuclear Cardiology. Source

Badra M.I.,Clemenceau Medical Center | Feldman D.S.,New York University | Hart R.A.,Oregon Health And Science University
Journal of Pediatric Orthopaedics Part B | Year: 2010

Selection of the appropriate fusion levels in thoracic adolescent idiopathic scoliosis has been traditionally a subject of debate among surgeons. Landmarks that have been suggested include the end vertebra, stable vertebra and neutral vertebra. Various results have been reported with multiple theories proposed to explain them. The clinical appearance of the patient, the type of the curve and its flexibility, the surgical technique and the instrumentation used all seem to play major roles in selecting the appropriate levels of fusion. © 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins. Source

Jambart S.,Saint - Joseph University | Ammache Z.,Clemenceau Medical Center | Haddad F.,King Hussein Medical Center | Younes A.,Private Practice | And 6 more authors.
Journal of International Medical Research | Year: 2011

The prevalence of painful diabetic peripheral neuropathy (DPN) was evaluated in type 1 or type 2 diabetes mellitus patients (n = 4097) attending outpatient clinics across the Middle East. Overall, 53.7% of 3989 patients with DN4 data met the criteria for painful DPN (Douleur Neuropathique-4 [DN4] scores ≥ 4). Significant predictors of painful DPN included long history (≥ 10 years) of diabetes (odds ratio [OR] 2.43), age ≥ 65 years (OR 2.13), age 50 - 64 years (OR 1.75), presence of type 1 versus type 2 diabetes (OR 1.59), body mass index ≥ 30 kg/m2 (OR 1.35) and female gender (OR 1.27). Living in one of the Gulf States was associated with the lowest odds of having painful DPN (OR 0.44). The odds of painful DPN were highest among patients with peripheral vascular disease (OR 4.98), diabetic retinopathy (OR 3.90) and diabetic nephropathy (OR 3.23). Because of the high prevalence and associated suffering, disability and economic burden of painful DPN, it is important that diabetic patients are periodically screened, using a simple instrument such as the DN4, and receive appropriate treatment if symptoms develop. © 2011 Field House Publishing LLP. Source

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