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Lake Clarke Shores, IA, United States

Clarke University is a four-year liberal arts college located in Dubuque, Iowa, United States, affiliated with the Roman Catholic Church in the Archdiocese of Dubuque. The campus is situated on a bluff overlooking the Mississippi River and picturesque downtown Dubuque. Clarke is known regionally as the "College for the Arts", and offers a broad undergraduate curriculum in 19 academic departments with over 40 majors and programs. The university also provides graduate master's and doctoral degrees in select areas of study and has a general enrollment of approximately 1,200 students. Wikipedia.

Bowman S.M.,State University of New York at Buffalo | Bowman S.M.,Clarke University | Patel M.,State University of New York at Buffalo | Patel M.,North Carolina State University | And 5 more authors.
BMC Plant Biology | Year: 2013

Background: Plants that utilize the highly efficient C4 pathway of photosynthesis typically possess kranz-type leaf anatomy that consists of two morphologically and functionally distinct photosynthetic cell types, the bundle sheath (BS) and mesophyll (M) cells. These two cell types differentially express many genes that are required for C4 capability and function. In mature C4 leaves, the plastidic rbcL gene, encoding the large subunit of the primary CO2 fixation enzyme Rubisco, is expressed specifically within BS cells. Numerous studies have demonstrated that BS-specific rbcL gene expression is regulated predominantly at post-transcriptional levels, through the control of translation and mRNA stability. The identification of regulatory factors associated with C4 patterns of rbcL gene expression has been an elusive goal for many years.Results: RLSB, encoded by the nuclear RLSB gene, is an S1-domain RNA binding protein purified from C4 chloroplasts based on its specific binding to plastid-encoded rbcL mRNA in vitro. Co-localized with LSU to chloroplasts, RLSB is highly conserved across many plant species. Most significantly, RLSB localizes specifically to leaf bundle sheath (BS) cells in C4 plants. Comparative analysis using maize (C4) and Arabidopsis (C3) reveals its tight association with rbcL gene expression in both plants. Reduced RLSB expression (through insertion mutation or RNA silencing, respectively) led to reductions in rbcL mRNA accumulation and LSU production. Additional developmental effects, such as virescent/yellow leaves, were likely associated with decreased photosynthetic function and disruption of associated signaling networks.Conclusions: Reductions in RLSB expression, due to insertion mutation or gene silencing, are strictly correlated with reductions in rbcL gene expression in both maize and Arabidopsis. In both plants, accumulation of rbcL mRNA as well as synthesis of LSU protein were affected. These findings suggest that specific accumulation and binding of the RLSB binding protein to rbcL mRNA within BS chloroplasts may be one determinant leading to the characteristic cell type-specific localization of Rubisco in C4 plants. Evolutionary modification of RLSB expression, from a C3 " default" state to BS cell-specificity, could represent one mechanism by which rbcL expression has become restricted to only one cell type in C4 plants. © 2013 Bowman et al.; licensee BioMed Central Ltd. Source

Weltin A.,Clarke University
American Journal of Nursing | Year: 2013

Background. The idea of a garden first surfaced during clinic visits with diabetic patients, during which the diabetes educator and I worked together to educate these patients on healthier food options. As experienced gardeners, we suggested they create their own home gardens as a way of ensuring healthiereating habits. But none of the Marshallese patients had experience gardening and didn't act on our suggestions. We realized we'd have to show them ourselves how to create and maintain a garden. It took us about a year to organize this effort, beginning with a discussion with their pastor. The church at which most Marshallese worship is a home that has been converted into a worship space; it has a large backyard, which the pastor agreed could be used to create a garden. Preparation. The husband of one of the RNs at the clinic rototilled the land in preparation for planting. A physician donated excess fencing from her farm property. We put up signs in the clinic and local hospital asking for donations, and people generously gave supplies like shovels, hoes, rakes, and tomato cages. We received a small donation from the hospital of $100 to purchase seeds and other supplies. Both the diabetes educator and I donated plants that multiply easily, such as strawberries, from our own gardens. Source

Vaassen M.M.,Clarke University
Ostomy Wound Management | Year: 2015

A variety of conditions result in lower extremity edema, such as deep vein thrombosis, cellulitis, venous stasis insufficiency, and congestive heart failure (CHF). A case study is presented to illustrate the dynamics of the lymphatic system, the pathology of CHF, the importance of obtaining a pretreatment differential diagnosis, and how to implement a safe treatment plan. The patient was a 69-year-old overweight woman with bilateral lower extremity lymphedema of almost equal volume (∼9,100 mL) of >2 months duration. She had 11 draining wounds and a reported history of chronic obstructive pulmonary disease (COPD) but no cardiac dysfunction. Treatment consisted of 6 sessions of manual lymph drainage (MLD), remedial exercises, and compression wrapping and weekly volumetric measurements over a period of 3 weeks. A 4-L decrease in lower extremity edema volume was noted, but fatigue and shortness of breath increased markedly. Treatment was discontinued and the patient was referred back to her physician for cardiac evaluation and treatment. The literature suggests patients, as well as health care professionals, do not always distinguish CHF symptoms from COPD. Proper assessment, monitoring, and lymphedema treatment adjustments are paramount to providing safe care for patients with signs and symptoms of COPD and suspected CHF. More research to elucidate best practice approaches in patients with lymphedema and concurrent CHF/COPD before the start of MLD treatment is warranted. Source

Mastroianni C.,University of Rome Tor Vergata | Piredda M.,University of Rome Tor Vergata | Piredda M.,Biomedical University of Rome | Taboga C.,Antea Formad | And 6 more authors.
Omega (United States) | Year: 2015

Nurses' attitudes toward caring for dying patients have an impact on the quality of the care provided. Education can improve knowledge and attitudes toward end-of-life care. No validated tool that measures such attitudes is available for Italian nursing students. The aim of this study was to translate the Frommelt Attitudes Toward Care of the Dying Scale (FATCOD) Form B from English into Italian and to establish its validity and reliability within an Italian population of students. A two-stage design was used. Stage 1 adapted the original version of the tool and tested it for content validity through a multistep process. Stage 2 tested its psychometric properties by analyzing internal consistency, test-retest reliability, and construct validity. The convenience sample consisted of 465 nursing students from all the universities of one Italian region. Measures of stability showed a very good overall (0.87) intraclass correlation coefficient (ICC). The discriminating capacity of the scale was adequate with good values of asymmetry and kurtosis for most of the items. Good internal consistency was found. The six factors derived from the factor analysis are the following: Fear/Malaise, Communication, Relationship, Care of the family, Family as Caring, and Active Care. FATCOD Form B-I is a valid, reliable, and acceptable tool for evaluation of attitudes toward end-of-life care in Italian students. It measures six specific dimensions that should be highlighted during health care student education and training. © The Author(s) 2015. Source

Malapati S.,Clarke University
ACS Symposium Series | Year: 2013

Food Chemistry was developed as an Honors course with a diversity component. Students first explored flavor, texture, nutrition, cooking methods and other traditional food chemistry topics. Students then used their knowledge to do small research projects in the chemistry laboratory and explored cuisine in the kitchen. Students experienced multiple ethnic cuisines and delved into the science behind how ingredients are used in different ways by different cultures. Each student group was responsible for one ethnic cuisine: from menu planning and ingredient sourcing, to cooking and serving, with an oral presentation that explored the nutritional and flavor profiles of the cuisine in general and the meal in particular and put them in a geographical and cultural context. In addition, students explored socioeconomic factors in cuisine by cooking in a chain restaurant and serving in a homeless kitchen. Honors students were thus able to integrate food chemistry into their liberal arts education. © 2013 American Chemical Society. Source

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