The City University of New York is the public university system of New York City. It is the largest urban university in the United States, consisting of 24 institutions: 11 senior colleges, seven community colleges, the William E. Macaulay Honors College at CUNY, the CUNY Baccalaureate for Unique and Interdisciplinary Studies Program at the Graduate Center, the doctorate-granting Graduate School and University Center, the City University of New York School of Law, CUNY Graduate School of Journalism, the CUNY School of Public Health and the Sophie Davis School of Biomedical Education. More than 270,000 degree-credit students and 273,000 continuing and professional education students are enrolled at campuses located in all five New York City boroughs. Its administrative offices are in mid-town Manhattan.The university has one of the most diverse student bodies in the United States, with students hailing from 208 countries. The black, white and Hispanic undergraduate populations each comprise more than a quarter of the student body, and Asian undergraduates make up 18 percent. Fifty-eight percent are female, and 28 percent are 25 or older. CUNY graduates include 13 Nobel laureates, a U.S. Secretary of State, a Supreme Court Justice, several New York City mayors, members of Congress, state legislators, scientists and artists.CUNY is the third-largest university system in the United States, in terms of enrollment, behind the State University of New York , and the California State University system. CUNY and SUNY are separate and independent university systems, although both are public institutions that receive funding from New York State. CUNY, however, is additionally funded by the City of New York. Wikipedia.
City University of New York | Date: 2016-09-29
A device for providing hands-optional mobility to a visually impaired toddler is disclosed. The device has a frame with vertical rods that connect to a toddlers body with a fastener. Curved surfaces at the distal ends of the rods slide along the floor and transmit tactile sensations to the toddler. Advantageously, the vertical rods are sufficiently flexible that the toddler cannot utilize the rods as walking aids.
Brigham, Women's Hospital and City University of New York | Date: 2016-07-18
This invention discloses drug-delivery compositions, methods of making prodrugs, and methods of drug delivery using a self-assembled gelator. The backbone of the gelator can contain a drug or prodrug, such as acetaminophen or salicin. Additional drugs or agents can be encapsulated in the gelator. Enzymatic or hydrolytic cleavage can be used to release the drugs.
City University of New York | Date: 2016-08-22
Fabry disease is a rare (incidence approximately 1 in 20,000) X-linked inborn error of glycolipid metabolism caused by a deficiency of the lysosomal enzyme, -galactosidase A, that leads to early death in affected males due to occlusive disease of the heart, kidney, and brain. The present invention provides a modified alpha-Galactosidase A enzyme derivative with improved stability and catalytic properties. As a result of the present invention, an effective therapeutic effect is achieved with a lower dose of enzyme infused to the patients.
City University of New York | Date: 2016-08-19
An impedance spectroscopy biosensor is provided that is fabricated on a stretchable substrate. The stretchable substrate is integrated with an impedance biosensor that undergoes cyclic strain without cracking.
City University of New York | Date: 2016-07-25
Structured beams, Bessel beams Laguerre beams, and focused Gaussian are used as a natural waveguide and its group velocity can be subluminal (slower than the speed of light) as compared to a Gaussian beam in free space. A free space dispersion relation for a Bessel beam, i.e., the dependence of its wavenumber on its angular frequency, is outlined from which the Bessel beams subliminal group velocity is derived. For reasonable conditions a Bessel light beam has associated parameters that allow slowing near a critical frequency. The application of Bessel beams for a natural optical buffer in free space is presented. Optical transitions and selection rules in materials are altered by structured light carrying orbital angular momentum (OAM). Nano antennas are used to enhance the interactions of structured light.
City University of New York | Date: 2017-01-26
This disclosure describes unique single stranded DNA templates having a characteristic sequence and secondary structure. The DNA templates disclosed herein are useful for making small RNA molecules through promoter-independent transcription by a mammalian RNA polymerase, and can serve as an effective vector for producing small RNA molecules of interest in vitro, in situ and in vivo in mammalian cells.
City University of New York | Date: 2017-03-15
A method of delivering a transgene to a cell is provided. The method uses a vector that contains a T-cell receptor alpha locus control region (TCRLCR) derived gene regulatory cassette having fewer than 5.0-kb. The method delivers the transgene with spatiotemporally specific gene expression and silencing-prevention controls to a cell such that a predetermined subset of progeny cell-types express a gene product from the transgene. Other progeny of the cell diminish, or silence, the expression of the gene product.
City University of New York and New York University | Date: 2017-02-15
The present invention relates to devices and methods of use thereof for detection of biomolecules, in vitro, in vivo, or in situ. The invention relates to methods of diagnosing and/or treating a subject as having or being at risk of developing a disease or condition that is associated with abnormal levels of one or more biomolecules including, but not limited to, inter alia, epilepsy, diseases of the basal ganglia, athetoid, dystonic diseases, neoplasms, Parkinsons disease, brain injuries, spinal cord injuries, and cancer. The invention also provides methods of differentiating white matter from gray matter. In some embodiments, regions of the brain to be resected or targeted for pharmaceutical therapy are identified using sensors. The invention further provides methods of measuring the neurotoxicity of a material by comparing microvoltammograms of a neural tissue in the presence and absence of the material using the inventive sensors.
City University of New York | Date: 2017-03-23
A secondary alkaline battery using manganese dioxide is described. The battery includes a mixed cathode material with birnessite-phase manganese dioxide or electrolytic manganese dioxide (EMD), a bismuth compound and a copper compound selected from the group consisting of elemental copper and a copper salt. In some embodiments, a conductive carbon and/or a binder may also be included.
City University of New York | Date: 2017-02-06
Certain neurological disorders are treated with dopamine agonists (e.g. L-Dopa) but these treatments unintentionally cause Levodopa-induced dyskinesias (LIDs) or tardive dyskinesia. An improved treatment is described that treats the patient with both a dopamine agonist and a Smoothened (Smo) agonist or with a dopamine agonist and combination of a Smoothened (Smo) agonist together with Amantadine.