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Elsayed E.A.,King Saud University | Elsayed E.A.,National Research Center of Egypt | Sharaf-Eldin M.A.,University of the Humanities | Sharaf-Eldin M.A.,National Research Center of Egypt | And 3 more authors.
Pakistan Journal of Zoology

Moringa peregrina belongs to the Moringaceae family and is native to the western part of Saudi Arabia and the eastern part of Egypt, from where it has been transferred to tropical and subtropical countries. The Moringa trees are highly appreciated for their nutritional and medicinal properties. In the past two decades, research has focused on investigating different parts of Moringa as a source for anticancer preparations. However, M. peregrina extracts were only evaluated for their antioxidant and anti-inflammatory activities, and the literature contains few (or no) information about the cytotoxic properties reported for M. peregrina seed oil. Accordingly, the current work aimed to evaluate the potential anti-proliferative properties of essential oil obtained from M. peregrina and its effects on various cell types. Different cell lines were exposed to increasing concentrations from the seed oil (0.15 to 1000 g/mL) for 24h, and cell toxicity was evaluated. Results revealed that all cell lines under investigation were significantly affected depending on the used oil concentration. Furthermore, cell lines showed different response to the treatment with oil according to cell type. Additionally, HepG2 and HeLa cells showed the highest response to the applied essential oil, followed by MCF-7, CACO-2 and L929, where the toxicity percentages at the maximal oil doses recorded 75.82, 75.35, 67.89, 57.50 and 53.43%, respectively. The IC50 value obtained for HeLa cells was 366.3 g/mL, and increased by 1.7-and 2.0-fold for HepG2 and CACO-2 cells, respectively. The present results suggest that essential oil isolated from M. peregrina seeds has potential cytotoxic properties against different cancer cell lines. Source

Sabra W.,TU Hamburg - Harburg | Sabra W.,Helmholtz Center for Infection Research | Sabra W.,Alexandria University | Haddad A.M.,Helmholtz Center for Infection Research | And 3 more authors.
World Journal of Microbiology and Biotechnology

Small-colony variants (SCVs) of Pseudomonas aeruginosa are often found in chronically infected airways of patients suffering from cystic fibrosis. These slow-growing morphological variants have been associated with persistent and antibiotic-resistant infections. Nevertheless, the behavior of SCVs under varied availability of O2 and iron, two key variables relevant to the lung environment of CF patients and pathogenicity of P. aeruginosa, has not been systematically studied so far. In this work, the effects of O2 and iron were comparatively studied for a CF P. aeruginosa wild type (WT) strain and its SCV phenotype in a real-time controlled cultivation system. Significant differences in the behavior of these strains were observed and quantified. In general, SCV exhibited a higher fitness than the WT toward aerobic conditions. Under iron rich condition, and despite less release of total extracellular proteins, absence of flagellin and lower siderophore production, the SCV cells grown at fully aerobic conditions showed a higher specific growth rate and a significantly higher cytotoxicity in comparison with the WT cells. The strains behaved also differently towards iron limitation. The phenomena of limited O2 transfer from the gas to the liquid phase and enhancement of formation of virulence factors under conditions of iron limitation were much more profound in the SCV culture than in the WT culture. These results have important implications for better understanding the pathogenicity of P. aeruginosa and its small-colony variants. © 2013 Springer Science+Business Media Dordrecht. Source

Khiyami M.A.,King Abdulaziz City for Science and Technology | Serour E.A.,King Abdulaziz City for Science and Technology | Serour E.A.,City for Scientific Research and Technology Applications | Shehata M.M.,King Abdulaziz City for Science and Technology | Bahklia A.H.,King Saud University
African Journal of Biotechnology

Biodiversity in geothermal springs in Saudi Arabia appears scanty and has not been thoroughly investigated. Geothermal springs are scattered in several areas in Saudi Arabia. Water samples were collected from ten hot springs and analyzed for different physical and chemical parameters. Fifteen isolates of thermo-aerobic bacteria were found. Bacillus cereus, B. licheniformis, B. thermoamylovorans, Pseudomonas sp., Pseudomonas aeruginosa and Enterobacter sp. were dominant in hot springs. Genetic relatedness indicated that eleven Bacillus spp. grouped together formed several clusters within one main group with high similarity. Plastic composite support tubes (PCS) were employed to stimulate the bacterial growth at high temperatures. The optimum temperature of isolates was 60°C. Thus, different blend of PCS were used to enhance the growth at higher temperatures. PCS blended with 20 and 15% (w/w) of dates pits and 5% (w/w) of yeast extract stimulated the growth of B. thermoamylovorans at 90°C. © 2012 Academic Journals. Source

Liang W.,Hunan University | Liang W.,Hunan University of Science and Technology | Zhang D.,Hunan University | You Z.,Hunan University | And 2 more authors.
Information Technology Journal

In order to reduce IP (Intellectual Property) infringements in VLSI (Very Large Scale Integration), many IP protection methods have been proposed. These methods have involved knowledge in fields of microelectronics, information hiding and embedded system. As a new field, IP protection can greatly reduce ownership misappropriation but it is faced with numerous challenges. On the basis of existing fundamental theories and engineering technologies, IP protection has rapidly developed in recent years. This study introduced IP protection in terms of concepts, characteristics and architecture. The challenges of IP protection technologies were analyzed. This study focused on the latest research improvement of IP protection technologies. The difficulties of digital watermarks on overhead, security, amounts were stated concretely. Meanwhile, this study presented some research methods for reference, such as multiple IP watermarking technology, models for watermark embedding and optimal computation, IP blind forensics technology and methods for evaluating watermark performance. © 2013 Asian Network for Scientific Information. Source

Husseien M.,Alexandria University | Amer A.A.,Alexandria Petroleum Company | El-Maghraby A.,City for Scientific Research and Technology Applications | Hamedallah N.,Alexandria University
International Journal of Environment and Waste Management

Oil spills impose a major problem on the environmental and economic impact. Mechanical recovery of oil is one of the most important countermeasures in marine oil spill. Development of the oil sorbent made of organic waste material were initiated in order to provide the resources for oil spill with less environmental load and cost. Corn stalk (agriculture residue) is widely spread throughout the world. The present technologically fast changing situation resulted to waste management practices; it is desirable that the disposal of plant waste should be done in a scientific manner by keeping in view the economic and pollution consideration. This is only possible when the plant waste has the potential to be used as a raw material for some useful products. This work examined the using of corn stalk waste agriculture in oil spill clean-up. The investigation revealed that particle size, sorbent weight, temperature, reusability and oil property are the most important factors affecting the oil-sorption performance of corn stalk waste agriculture. The higher sorption capacity of oil was 11.04, 9.65 and 3.95 g oil/g sorbent according to oil type, these values were achieved by using 0.8 mm particle size and 15 minutes sorption time at 20 ± 1°C bath temperature. © Copyright 2015 Inderscience Enterprises Ltd. Source

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