City Clinical Hospital No30

Nizhniy Novgorod, Russia

City Clinical Hospital No30

Nizhniy Novgorod, Russia
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Kurysheva M.A.,City Clinical Hospital No30 | Klemenov A.V.,City Clinical Hospital No30
Sovremennye Tehnologii v Medicine | Year: 2011

The prognosis of primary biliary cirrhosis enables to determine optimal time for liver transplantation. There has been presented the case of using Mayo risk score taking into account the parameters available for a physician to prognosticate survival rate and determine the surveillance of the female patient with primary biliary cirrhosis.


Shakhov A.V.,City Clinical Hospital No30 | Laganin A.A.,City Clinical Hospital No30 | Ershov V.V.,City Clinical Hospital No30 | Kleimentiev Ye.V.,City Clinical Hospital No30
Sovremennye Tehnologii v Medicine | Year: 2014

There has been described a case of combined endoscopic therapy (tumor pre-stenting followed by laparoscopy-assisted radical surgery) of sigmoid colon cancer complicated by bowel obstruction. A patient suffered from stage IV obesity and had undergone left nephrectomy before, which resulted in a secondary adhesive process in surgical area.


Krupin A.V.,City Clinical Hospital No30 | Krupin V.N.,Nizhny Novgorod State Medical Academy
Sovremennye Tehnologii v Medicine | Year: 2011

The antibacterial therapy of chronic bacterial prostatitis in use does not always lead to the disappearance of clinical symptoms, does not prevent recurrences and is not always efficient concerning inflammation agent due to the peculiarities of prostate blood supply. At the same time, healthy prostatic fluid is able to suppress the generation of the majority of pathogenic bacteria including clamydia. The aim of the study is to clarify the role of prostate functional recovery in treating chronic bacterial prostatitis (class II) and achieving a long-term therapeutic effect. Materials and methods. There were examined 1106 males, aged 24-52, with clinical presentation of chronic prostatitis, and in 345 of them (31.2%) a bacterial component of the inflammation was confirmed by laboratory findings. The patients were divided into two groups. Results. The treatment results of 2 groups were compared. 1st group patients (n=189) were treated using a traditional approach and in the 2nd group (n=156) the therapy objective was to recover prostate functional capabilities without antibiotics administration despite of the presence of leukocytes in prostate exprimate and bacterial culture. The comparison showed a positive effect of prostate trophism recovery on the course of an inflammatory process. The inflammatory process in prostate (clinical symptoms disappearance, the reduction of white blood count in prostatic fluid) was stated to stop despite of the presence of microflora revealed in bacterial inoculation.


Klemenov A.V.,City Clinical Hospital No30 | Suslov A.S.,City Clinical Hospital No30
Sovremennye Tehnologii v Medicine | Year: 2014

Hereditary connective tissue disorders - a genetically and clinically heterogeneous group of diseases united by common congenital mesenchymal abnormalities - is one of the most debatable problems of clinical medicine. A great while, from the whole variety of hereditary connective tissue disorders, only "differentiated" (with concerted diagnostic recommendations), monogenic syndromes registered in OMIM, have been the focus of attention of medical community. However, numerous unclassifiable forms with multi-factorial development mechanisms or so called dysplastic phenotypes have not been taken into account when estimating the disease prognosis and determining treatment policy. The review represents the current concepts of the nomenclature of hereditary connective tissue disorders, and considers the diagnostic criteria of the classified monogenic syndromes (Marfan syndrome and Ehlers-Danlos syndrome, MASS-phenotype, primary mitral valve prolapse, joint hypermobility syndrome) and unclassifiable dysplastic phenotypes (M{cyrillic}ASS-like phenotypes, marfanoid appearance, Ehlers-like phenotype, benign joint hypermobility, unclassifiable phenotype) in the view of recent international and domestic recommendations. Congenital mesenchymal disorders have been represented in the form of a continuous list in order of decreasing clinical intensity of their manifestations and prognostic value reduction ("phenotypic continuum"): from monogenic syndromes through dysplastic phenotypes to unclassifiable phenotypes. The authors have laid emphasis on the difficulties of clinical identification of hereditary connective tissue disorders related to non-specificity of external and visceral markers of connective tissue weakness and certain conventionality of diagnostic criteria. The review has shown the debating aspects of diagnosis and interpretation of clinical significance of some hereditary connective tissue disorders.

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