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Mexico City, Mexico

Cruz-Benitez L.,Servicio de Oncologia Quirurgica | Morales-Hernandez E.,Cirugia Oncologica
Gaceta Mexicana de Oncologia | Year: 2014

Introduction: Surgical treatment of breast tumors has undergone several modifications over time, from being an aggressive and mutilating procedure as classical radical mastectomy, to become a surgery in our present increasingly conservative, focused on decreasing the psychological impact that this condition prints to patients. Objective: Introduce through a systematic review in the world medical literature, the development undergone by different surgical techniques for the management of breast tumors over time. Methods: Was carried out through a search in Internet servers such as Medline, Scielo, PubMed, among others, in order to locate medical articles concerning this topic. Conclusions: The treatment of operable breast cancer is no longer a radical surgery, bloody, mutilating, which existed as the only treatment option, into an increasingly conservative surgery, performed in a cosmetically acceptable and which is equivalent to performing mastectomy with respect to recurrence and survival. © 2014 Gaceta Mexicana de Oncología. Publicado por Masson Doyma México S.A.

Medina-Villasenor E.A.,Cirugia Oncologica | Oliver-Parra P.A.,Clinica de Colposcopia | Neyra-Ortiz E.,Hospital Angeles Metropolitano | Perez-Castro J.A.,Medico Pasante | And 2 more authors.
Gaceta Mexicana de Oncologia | Year: 2014

Introduction: Cervical intraepithelial neoplasia (CIN) is the most common pre-malignant lesion. Atypical squamous changes occur in the transformation zone of the cervix with mild, moderate or severe changes described by their depth (CIN 1, 2, 3). Human papillomaviruses (HPVs) are a group of more than 100 DNA viruses that infect human epithelial cells. About 15 of these viruses can cause intraepithelial lesions and cervical cancer. Persistent high-risk HPV types can cause cancer of the lower genital tract if not treated. Up to 79% of sexually active women acquire a genital HPV infection during their lifetime, but the infection is usually transient and asymptomatic. Objective: Analyze the sociodemographic characteristics, risk factors and presenting symptoms in patients with pre-invasive cervical disease. Material and methods: A retrospective, observational and descriptive study of electronic files from patients with CIN from March 2002 to March 2012. Results: Five hundred sixty eight patients were included, the most common age of CIN was 24-45 years, the age of first intercourse was 16 years, mostly had multiple sexual partners. Other risk factors found were: high parity, sexually transmitted diseases, tobacco smoking, and use of oral contraceptives. In 85.22% of cases presented with nonspecific symptoms such as itching, genital burning, and vaginal discharge. Only 9.85% of cases presented with classic signs of infection with HPV like genital warts in the lower genital tract. The cervicovaginal cytology had a sensitivity of 64.47%, the diagnosis of ASCUS was detected in 17.26%. The colposcopic study showed acetowhitening lesion, vessels of fine caliber, fine mosaic and iodine negative in 75% of cases that corresponded to low grade lesion. HPV testing (through polymerase chain reaction testing) was performed in 17.26% of cases with ASCUS. The histopathological study was 83.98% CIN1, 6.87% CIN2 and 9.15% CIN3. Conclusions: The cervical pre-invasive lesion has similar risk factors for cervical cancer. The HPV is a necessary, but not the unique factor for the progression to invasive cancer. CIN is initially asymptomatic, spontaneously refers, in latent phase can only be detected by HPV tests. When there are symptoms, they are nonspecific and can be detected by colposcopy and Pap smear, but there are false positives and false negatives. The histopathological study of cervical biopsy is needed to determine the high grade lesions, which are the true precursors of invasive cancer. © 2014 Gaceta Mexicana de Oncologia.

Torres-Lobaton A.,Ginecologia Oncologica | Torres-Rojo A.,Cirugia Oncologica | Roman-Bassaure E.,Servicio de Oncologia | Morales-Palomares M.A.,Cirugia Oncologica | Morgan-Ortiz F.,Autonomous University of Sinaloa
Ginecologia y Obstetricia de Mexico | Year: 2010

Background: Pelvic exenteration offers the last chance of cure for some patients with cervical cancer recurrent after radiation therapy. Objective: To analyze factors associated with recurrence and survival after pelvic exenterations, based on a 40 years institutional experience. Material and method: Retrospective, logitudinal and closed study from files of patients who survived to exenterative procedures at Oncology Department at the Hospital General de México, from January 1966 to December 2006, were screened in order to know risk factors predicting recurrence and survival in a follow up for at least three years. Results: Prognostic factors in 161 patients eligible for this analysis were: diagnosis of recurrence prior 1 year 44/96 (45.8%) vs. 27/41 (65.8%) diagnosis after this time (p = 0.03), central recurrences 32/38 (84.2%) vs. 14/49 (28.5%) infiltration of lateral wall of the pelvis (0.0001), patients with 35 years old or less had a better prognosis when compared with the others: 23/33 (69%) vs. 60/128 (46%), (0.01); Infiltration of urinary bladder and or rectal wall 30/75 (40%) vs. 53/86 (61%) absence of these (0.006), tumor involving myometrium with or without adnexal metastases 6/25 (24%) vs. 77/136 (56%) absence of these reports (0.002), presence of three or more positive lymph nodes 5/16 (31%) vs. 56/90 (62%) absence of lymph nodes metastasis (0.02) and findings of hydronephrosis 2/15 (13.3%) vs. 13/19 (68.4%) of normal reports (0.01). Conclusions: Better evolution in this series was for patients who had central recurrences.

Rioja Martin M.E.,Medicina Nuclear | Ortega Perez G.,Cirugia Oncologica | Cabanas Montero L.J.,Cirugia Oncologica | Munoz-Madero V.,Cirugia Oncologica | Cabanas Navarro L.,Cirugia Oncologica
Revista Espanola de Medicina Nuclear | Year: 2011

Sentinel node biopsy has become the standard practice in lymph node staging in breast cancer in early stages. However, uncertainty remains regarding the best method of radiotracer/dye injection. Currently, the subareolar injection is being widely used because of its technical simplicity and higher rates of SN location versus the so-called deep techniques (peritumoral, intratumoral) that require greater specialization and greater use of resources in the non-palpable lesions.We present a case of a discrepancy between the two techniques that could have caused a false negative. © 2010 Elsevier España, S.L. y SEMNIM.

Monges-Jones J.E.,Cirugia Oncologica | Gonzalez-Jauregui-Diaz F.,Centro Medico ABC | Armando Sanchez J.,Cirugia Oncologica | Meza-Diaz R.,Cirugia Oncologica | And 2 more authors.
Gaceta Mexicana de Oncologia | Year: 2013

Kidney cancer represents 3% of the malignant neoplasms. Presentation can be sporadic or hereditary. The hereditary presentation has a variety with renal oncocytoma associated to Birt-Hogg-Dubé syndrome. This syndrome is characterized with skin lesions (fibrofolliculoma, trichodiscoma), renal neoplasms and lung cysts/ spontaneous pneumothorax. A 16-year-old female, who began in June 2010 with right iliac fosse pain. During the physical examination fibrofolliculoma plaque lesions on cheeks were found, abdomen with palpable mass in right flank, firm, mobile, and painless to palpation. Imaging studie were requested, computerized axial tomography (CT): renal tumor abdmen. Right radical nephrectomy was performed. Histopatologic diagnosis of renal cancer. A control chest CT was performed and hydropneumothorax was found, left chest tube was placed. © 2013 Gaceta Mexicana de Oncología. Publicado por Masson Doyma México S.A.

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