CINOGY GmbH

Duderstadt, Germany

CINOGY GmbH

Duderstadt, Germany
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An electrode arrangement for forming a dielectric barrier plasma discharge between a flat surface (4) of the electrode arrangement and a surface to be treated which functions as a counter surface and on which a fluid can collect, comprising a flat electrode (14) which can be connected to a high-voltage source by means of a connector and which is completely embedded in a flat dielectric (2), except for the connector for the high-voltage source, wherein the dielectric (2) forms an upper surface (1) and a lower surface (4) which appears as a flat surface to the surface to be treated, enables the drainage or supply of a fluid by means of a simple design. The flat electrode (14) has through openings (15) distributed across the surface thereof, and the dielectric (2) is provided with through openings (3) which extend from the lower surface (4) to the upper surface (1) and which align with the through openings (15) of the electrode (14) and which have smaller dimensions than the through openings (15) of the electrode (14), so that the dielectric (2) is also completely covered in the region of the through openings (15) of the electrode (14).


Rajasekaran P.,Ruhr University Bochum | Mertmann P.,Ruhr University Bochum | Bibinov N.,Ruhr University Bochum | Wandke D.,CINOGY GmbH | And 3 more authors.
Plasma Processes and Polymers | Year: 2010

The reported dielectric barrier discharge (DBD) source comprises of a ceramic-covered copper electrode, and plasma can be ignited in ambient air with grounded Opposite' electrodes or with objects of high capacitance (e.g., human body), when breakdown conditions are satisfied. Filamentary plasma mode is observed when the same source is operated using grounded opposite electrodes like aluminium plate and phosphate buffered saline solution, and a homogeneous plasma mode when operated on glass. When the source is applied on human body, both homogeneous and filamentary discharges occur simultaneously which cannot be resolved into two separate discharges. Here, we report the characterization of filamentary and homogeneous modes of DBD plasma source using the above mentioned grounded electrodes, by applying optical emission spectroscopy, microphotography and numerical simulation. Averaged plasma parameters like electron velocity distribution function and electron density are determined. Fluxes of nitric oxide, ozone and photons reaching the treated surface are simulated. These fluxes obtained in different discharge modes namely, single-filamentary discharge (discharge ignited in same position), stochastical filamentary discharge and homogeneous discharge are compared to identify their applications in human skin treatment. It is concluded that the fluxes of photons and chemicallyactive particles in the single filamentary mode are the highest but the treated surface area is very small. For treating larger area, the homogeneous DBD is more effective than stochastical filamentary discharge. (Figure Presented) © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Rajasekaran P.,Ruhr University Bochum | Oplander C.,RWTH Aachen | Hoffmeister D.,University of Science and Arts of Iran | Bibinov N.,Ruhr University Bochum | And 3 more authors.
Plasma Processes and Polymers | Year: 2011

Atmospheric-pressure dielectric barrier discharge (DBD) in air is investigated for medical applications, especially for skin treatment. When the DBD was tested on mouse skin, a homogeneous discharge accompanied by filamentary microdischarges is observed. For characterization of the homogeneous discharge, averaged plasma parameters (namely electron density and electron velocity distribution function) and gas temperature are determined by optical emission spectroscopy, microphotography and numerical simulation. Chemical kinetics in the active plasma volume and in the afterglow is simulated. Fluxes of biologically useful molecules like nitric oxide (NO) and ozone reaching the treated surface and irradiation by UV photons are determined. Skin biopsy results show that DBD treatment causes no inflammation and no changes in the skin-collagen. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Brehmer F.,University of Gottingen | Haenssle H.A.,University of Gottingen | Daeschlein G.,University of Greifswald | Ahmed R.,Institute fur Anwendungsorientierte Forschung und Klinische Studien IFS GmbH | And 6 more authors.
Journal of the European Academy of Dermatology and Venereology | Year: 2015

Background: Cold atmospheric plasma (CAP, i.e. ionized air) is an innovating promising tool in reducing bacteria.Objective: We conducted the first clinical trial with the novel PlasmaDerm® VU-2010 device to assess safety and, as secondary endpoints, efficacy and applicability of 45 s/cm2 cold atmospheric plasma as add-on therapy against chronic venous leg ulcers.Methods: From April 2011 to April 2012, 14 patients were randomized to receive standardized modern wound care (n = 7) or plasma in addition to standard care (n = 7) 3× per week for 8 weeks. The ulcer size was determined weekly (Visitrak®, photodocumentation). Bacterial load (bacterial swabs, contact agar plates) and pain during and between treatments (visual analogue scales) were assessed. Patients and doctors rated the applicability of plasma (questionnaires).Results: The plasma treatment was safe with 2 SAEs and 77 AEs approximately equally distributed among both groups (P = 0.77 and P = 1.0, Fisher's exact test). Two AEs probably related to plasma. Plasma treatment resulted in a significant reduction in lesional bacterial load (P = 0.04, Wilcoxon signed-rank test). A more than 50% ulcer size reduction was noted in 5/7 and 4/7 patients in the standard and plasma groups, respectively, and a greater size reduction occurred in the plasma group (plasma -5.3 cm2, standard: -3.4 cm2) (non-significant, P = 0.42, log-rank test). The only ulcer that closed after 7 weeks received plasma. Patients in the plasma group quoted less pain compared to the control group. The plasma applicability was not rated inferior to standard wound care (P = 0.94, Wilcoxon-Mann-Whitney test). Physicians would recommend (P = 0.06, Wilcoxon-Mann-Whitney test) or repeat (P = 0.08, Wilcoxon-Mann-Whitney test) plasma treatment by trend.Conclusion: Cold atmospheric plasma displays favourable antibacterial effects. We demonstrated that plasma treatment with the PlasmaDerm® VU-2010 device is safe and effective in patients with chronic venous leg ulcers. Thus, larger controlled trials and the development of devices with larger application surfaces are warranted. © 2014 European Academy of Dermatology and Venereology.


A plasma treatment device for treating a surface with a dielectrically impeded plasma field which is generated between an electrode (16), to which a high voltage is supplied, and the surface, wherein the electrode (16) forms, with a dielectric (17) surrounding the electrode (16), a roller (6) mounted rotatably in a grip housing (1), which roller can be rolled on the surface, has an extended treatment field and enables defined and controlled plasma treatment of the surface by virtue of the fact that the roller (6) is designed such that it can be matched flexibly to irregularities on the surface and has a rolling area with elevations (19, 19), between which interspaces (20) forming the plasma field are located.


In order to treat human or animal hair fixedly arranged on a sopport, hair is divided into strands. The divided strands are subjected to a dielectric plasma treatment by drawing an apparatus connected to a high voltage source (8) through the strands. The apparatus can be in the form of tongs or have a comb-like structure.


Patent
CINOGY GmbH | Date: 2013-07-18

An electrode arrangement for forming a dielectrically impeded plasma between an active surface of a flexible, planar electrode that can be connected to a high voltage source has a planar, flexible dielectric that forms the active surface which is connected to the planar electrode to form an electrode element where the electrode is completely covered towards to surface to be treated. The electrode arrangement is adaptable to irregular surfaces using a contact with surface elasticity for pressing onto the rear face of the electrode element facing away from the surface such that the electrode element by local deformation is automatically adapted to the irregularities.


The invention relates to a flexible flat electrode arrangement for a dielectrically limited gas discharge, comprising a central region (3), an edge region, and a flat electrode (14) which conducts a high-voltage potential and which is embedded in a flat dielectric that forms an upper face (10) and a contact face (6). The invention allows the active surface of the electrode arrangement to be matched to the size of a surface to be treated in that the flat dielectric is in the form of a flat strip (1) wound into a spiral at least in the edge region, and the electrode (14) is formed by at least one electric conductor which runs in the longitudinal direction of the wound strip (1) and which leads into an end surface (13) of the strip (1).


Patent
Cinogy Gmbh | Date: 2014-11-07

A device for treating a surface with a dielectric barrier plasma, wherein the surface functions as a return electrode, having a housing (1), in which a high-voltage feed line, an electrode (8) which is connected to the high-voltage feed line, and a dielectric (9), which screens the electrode (8) with respect to the surface, are located, permits the plasma treatment of highly curved surfaces and of relatively large surface areas by virtue of the fact that the electrode (8) has the shape of a circle which is mounted in the housing (1) so as to be rotatable at least to a limited degree, and projects with a spherical section from an end-side opening (5) in the housing (1), and in that the electrode (8) is coated with the dielectric (9) in such a way that its spherical section projecting out of the housing (1) is covered by the dielectric (9) in every possible rotational position.


Patent
Cinogy Gmbh | Date: 2014-11-06

A device for treating a body surface of a living body by means of a dielectric barrier discharge plasma, with a planar, flexible dielectric (4) by which an electrode (1) attached to a high voltage source (3) is screened off from the body surface and which is suitable for placing on the body surface, functioning as counter-electrode, and is designed with a structured surface (7) which provides a gas space for the plasma discharge between dielectric (4) and body surface, which device permits the conduct of plasma treatment and the delivery of curative or healing substances without a change of the position of the device, by virtue of the fact that a layer (11) composed of a solid, open-pore matrix of a curative or healing material is arranged on the surface (7) of the dielectric (4).

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