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Trieste, Italy

Marega A.R.,University of Namur | Bergamin M.,Protos Research Institute | Aroulmoji V.,Protos Research Institute | Dinon F.,Cimteclab Spa | And 2 more authors.
European Journal of Organic Chemistry

Carbon nanotube (CNTs) derivatives are nowadays under thorough investigation as biomedically interesting materials. In this paper we describe a method for the preparation of water-soluble CNTs by condensation of the carboxylic groups introduced onto the carbon framework and the primary amine moieties inserted in the naturally occurring biopolymer hyaluronan (HA). The covalent conjugation between CNTs and HA should merge the biocompatibility and further processability of the HA chains with the well-known cellular penetration properties of the CNT derivatives to produce novel drug delivery platforms. In fact, thanks to the primary amino groups introduced in the HA chains, HA-CNT derivatives can be further covalently modified with model drugs like ibuprofen and methotrexate. We describe also the monitoring of all the CNT derivatization steps by diffusion-ordered NMR spectroscopy (DOSY), a technique that allows fast and reliable characterization of these novel derivatives. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

Campaner P.,Cimteclab Spa | D'Amico D.,Cimteclab Spa | Ferri P.,Cimteclab Spa | Longo L.,Cimteclab Spa | And 3 more authors.
Macromolecular Symposia

The aim of this work is the development of composite pipes using renewable resources. The pipes, manufactured by filament winding technology, were obtained using an epoxy resin crosslinked with a cardanol based novolac as matrix and jute fibres as reinforcement. Cardanol is a natural oil extracted from the shell of the cashew (Anacardium occidentale L.) nut. An amount of natural materials higher than 50% by weight was achieved in the final composites. Tensile and parallel plate compression tests were carried out on the composite pipes. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

Benedetti E.,Composite Technical Services Inc. | Weir J.,Composite Technical Services Inc. | Campaner P.,Cimteclab Spa | Minigher A.,Cimteclab Spa | And 3 more authors.
International SAMPE Symposium and Exhibition (Proceedings)

By combining an innovative lamellar machine developed and recently patented by VEM and new bio-based prepolymers and polymers developed by Cimteclab, a process for the production of a different kind of fiber composite pipes by filament winding (FW) technology has been recently optimized. The FW machine used possesses axial metallic lamellas which advance the pipe while rotating; so, apart from many mechanical advantages like faster production, maintenance costs reduced, easier assembly and faster diameter change, a wide range of different tubular articles can be realized by simply varying process conditions. As a further implementation, we explored the use of new cardanol based polymers (novolacs, polyols,...), to develop a sustainable and high-efficient process, to be applied for example, but without any limitation, to the production of pipes insulated with a cardanol based rigid polyurethanic foam. Source

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