Mosihuzzman M.,University of Karachi |
Naheed S.,Jinnah University for Women |
Hareem S.,University of Karachi |
Talib S.,University of Karachi |
And 6 more authors.
Life Sciences | Year: 2013
Aims One of the aims of this research work is the isolation and identification of various constituents of two medicinally important plants (Iris loczyi and Iris unguicularis). Secondly, the prime aim is the biological evaluation of these natural products to discover new potential inhibitors of α-glucosidase enzyme and protein glycation. Main methods Plants of the genus Iris contain a variety of secondary metabolites. Chromatographic techniques were applied for the isolation of different compounds from Iris loczyi and Iris unguicularis. All the isolated compounds were screened for their α-glucosidase enzyme inhibition and antiglycation potential. Key findings It is shown in the results that two compounds (Kaempferol and 8-Methoxyeriodictyol) isolated from plant Iris unguicularis and compounds (Arborinone and 5,7-dihydroxy-2′,6-dimethoxyisoflavone) isolated from plant Iris loczyi possess promising activity against α-glucosidase enzyme as compare to acarbose which is used as a standard α-glucosidase inhibitor in this study. A flavanone (2′,5-dihydroxy-6,7-methylenedioxy) isolated from Iris loczyi was explored as most active anti-glycating agent. Significance α-Glucosidase enzyme is a therapeutic target to treat carbohydrate mediated diseases. In this study various inhibitors of α-glucosidase are identified which might be important for the management of diabetes. Similarly, antiglycation agents may have application for the management of late diabetic complications. © 2012 Elsevier Inc.
Razzaq A.,CIIT Abbottabad |
Razzaq A.,Polytechnic University of Turin |
Orefice M.,Polytechnic University of Turin
IEEE Antennas and Propagation Society, AP-S International Symposium (Digest) | Year: 2015
A miniaturized antenna for printed circuits radiating at Industrial Scientific and Medical (ISM) band (center frequency 2.44 GHz) has been designed and simulated. A prototype has been developed, manufactured and tested for reflection coefficient and radiation pattern. Prototype measurement results shows a good agreement with simulations. The size of the antenna is smaller than 0.1 λ. The presence of components around the antenna has been considered, and their effect on the resonance has been studied. The variation of resonant frequency as a function of the component position and orientation has been summarized in a plot. © 2015 IEEE.
Khan K.,CIIT Abbottabad |
Sher H.,King Saud University |
Iqbal M.,Pakistan Cereal Crops Research Institute |
Al-Qurainy F.,King Saud University
African Journal of Agricultural Research | Year: 2011
Maize (Zea mays L.) is the second most important summer cereal crop after wheat in Khyber Pakhtoonkhua province of Pakistan. It occupies more than 27% of the total cropped area of the province, however, with a very low yield as compared to the achievable potential of 10 t ha -1. Such a low average yield is primarily due to a widespread use of low-yielding open-pollinated maize cultivars by farmers in different areas of the province. In the year 2000, Hybrid-oriented maize breeding research work for the development of indigenous maize hybrids was initiated at the cereal crops research institute (CCRI), Pirsabak, Nowshera, Pakistan. The main objective was to evolve single-cross maize hybrids of high yield potential, white kernel and low to medium maturity for the environments of Khyber Pakhtoonkhua province. A large number of replicated field experiments, both on-station and on-farm, were carried out in 2005 and 2006 to evaluate the experimental hybrids. Grain yield, Stover yield, and maturity were among the important traits used in these investigations. A highest grain yield of 9.84 t ha -1, and a Stover yield of 30.56 t ha -1, with maturity earlier than other hybrids, including a leading maize hybrid of private sector (Pioneer-3025) were observed for one of the experimental hybrids, FRW-2 x FRW-8. This hybrid with a few exceptions was invariably found higher yielding and early maturing as compared to other hybrids included in the trials. The new experimental hybrid was officially named as "Kiramat". The results of the current study provided a sound basis for its approval by the 'Provincial Seed Council' and its registration by the 'Federal Seed Certification and Registration Department' for commercial cultivation. © 2011 Academic Journals.
Shahzad K.,Hazara University |
Umer A.I.,Hazara University |
Nazir B.,CIIT Abbottabad
ICNSC 2015 - 2015 IEEE 12th International Conference on Networking, Sensing and Control | Year: 2015
In modern data centres (DCs), energy consumption and resource management are challenging tasks. So in large virtualized DCs, performance of applications is highly dependent on energy-Aware DC architecture and smooth network communication between virtual machines (VMs), while minimizing the communication burden to avoid congestion, latency etc. The communication cost of a network can be reduced by minimizing the VMs migration between physical machines (PMs). Therefore customer as well as service providers need cloud computing solutions that not only minimize operational costs, but also total network load. Minimizing the use of energy/network communication overhead with maximum resource utilization in large DCs is a challenging task as computing applications and data are growing so quickly for which increasing larger servers and disks are required to process them fast enough within the required time period. In order to minimize network load and maximize resource utilization in cloud DCs, we simulated our proposed network load-Aware scheduling algorithm that ensures minimum VMs migration while delivering the negotiated Quality-of-Service (QoS). Our simulation also shows results with different bit rates. © 2015 IEEE.
Aurangzeb N.,Hazara University |
Irshad M.,CIIT Abbottabad |
Hussain F.,University of Peshawar |
Mahmood Q.,CIIT Abbottabad
Journal of the Chemical Society of Pakistan | Year: 2011
Heavy metal (HM) pollution of waters, soils and vegetation is a major ecological problem that needs to be investigated. The present study involved the collection of soil samples and natural vegetations (Tribilas terristris, Lepia nodiflora, Amaranthus viridis, Heliotropium euoropeum, Coronopis didymus, Cynodon ductylon, Chenopodium murale and Eclipta alba) from the vicinity of wastewater canal and subsequent analysis for their HM concentrations. Results showed that HM concentrations varied within the species of vegetation and type of metal analyzed. The order of vegetation for metal concentrations was A. viridis > E. alba > H. euoropeum > L. nodiflora > C. murale > C. didymus > C. ductylon > T. terristris. Metals prevailed in plants in the decreasing order of Fe > Mn > Zn > Pb > Cr > Cu > Cd, irrespective of the vegetation. Metal prevalence in soils was in the order of Fe > Mn > Cd > Cr > Pb > Zn > Cu. Samples near canal were found with higher level of Mn, Pb and Zn as compared to soil away from canal water. Distant sampling gave higher accumulation of Cd, Cr, Cu and Fe as compared to the soil nearby wastewater. The analyzed species of HM in the soils and plants may indicate the variability of their composition in wastewater.
Khan L.,CIIT Abbottabad |
Khan M.U.,CIIT Abbottabad |
Qamar S.,CIIT Abbottabad
ICIAS 2012 - 2012 4th International Conference on Intelligent and Advanced Systems: A Conference of World Engineering, Science and Technology Congress (ESTCON) - Conference Proceedings | Year: 2012
The suspension system aims to support vehicle body. It provides passenger comfort and vehicle stability by isolating road disturbances. Passive suspension systems can't handle the tradeoff between passenger safety and vehicle stability. Active control has the ability to handle this tradeoff and provide both vehicle stability and passenger safety. Different active controllers based on adaptive Takagi Sugeno Kang (TSK) are developed for active suspension system and are simulated on full-car's model suspension in MATLAB/SIMULINK. The adaptive fuzzy controller's inference consists of different Degree of Fulfillment (DOF), differentiating control strategies compared to others, also showing importance of choosing proper DOF for selection of proper rules. The performance and effectiveness of the proposed scheme based active suspension system is compared with passive and active suspension system. © 2012 IEEE.
Irshad M.,COMSATS Institute of Information Technology |
Eneji A.E.,University of Calabar |
Hussain Z.,CIIT Abbottabad |
Ashraf M.,CIIT Abbottabad
Journal of Soil Science and Plant Nutrition | Year: 2013
Effect of composting on the extractability of plant nutrients in organic wastes is essential for their recycling in sustainable soil fertility management. Therefore, an experiment was carried out to determine the concentrations of total C, total N, extractable P, K, Na and B in five types of fresh and composted manures (namely buffalo, camel, cow, goat and poultry). Laboratory results showed that the extractability of elements varied considerably with the type of composted manure. Total C varied in the order cow > goat > buffalo > poultry > camel while total N was in the order buffalo > poultry > cow > camel > goat. Total C, total N, extractable K and Na decreased with composting, whereas extractable P and B increased. Goat manure had higher pH and EC values than cow and poultry manures whether in fresh or composted samples. A marked increase in the EC value was observed in composted manures, whereas pH was reduced with composting.
Nawaz M.,CIIT Abbottabad |
Nisar U.B.,CIIT Abbottabad |
Ali Bukhari S.A.,CIIT Abbottabad |
Khan S.,University of Peshawar
Journal of Himalayan Earth Sciences | Year: 2015
The research mainly involves the petrophysical analysis of Chanda deep-01 and to mark the best reservoir zone while second part of the research work was to correlate the Lockhart Limestone of Chanda deep-01 with exposed Lockhart Limestone at Nathia Gali in Hazara region on the basis of porosity and thickness. To interpret petrophysical properties, different logs were used which include gamma ray log, neutron log, density log, long latero log, spontaneous potential and sonic log. Exposed Lockhart Limestone unit was studied in the eld and petrographically analyzed. The thickness acquired from eld was 242m while porosity estimated by thin section study was about 11% .The petrophysical properties calculated at Chanda deep-01 well estimated the thickness to be 170m and porosity to be 9.5% along with volume of shale 5.5% and water saturation 29.3%. In the same zone, hydrocarbon saturation turned out to be 70.6%. These values conrmed Lockhart limestone to be the best reservoir in Chanda deep-01 well. The exposed unit in Hazara was then correlated and the porosity difference with subsurface unit in Chanda deep-01 was estimated to be 1.86%. The changes in porosity at different locations of same formation were interpreted to be due to overburden pressure, facies changes, diagenesis and pressure dissolution. © 2015 National Centre of Excellence in Geology. All rights reserved.