Seoul, South Korea

Chung - Ang University

www.cau.ac.kr/
Seoul, South Korea

Chung-Ang University is a notable private university based in Seoul.Starting as a church-run kindergarten in 1918, CAU transformed into a female school for kindergarten teachers in 1922 and was granted university status in 1953. The university claimed 2018 to be their centennial. It has 33,600 undergraduates, 5,200 graduates, 700 professors and 500 more part-time teaching staff.CAU is the first in South Korea to offer courses in Pharmacy, Business Management, Mass Communication, Advertising & Public Relations, Creative Writing, Photography, and Drama & Film Studies, and is active in Pharmacy, Media and the Arts. Wikipedia.

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The present invention relates to a ribosomal DNA nontranscribed spacer (rDNA NTS)-based gene multiple insertion cassette set and a GRAS-grade recombinant yeast strain using the same. In particular, a gene multiple insertion cassette set including rDNA NTS fragments and an auxotrophic selection marker having an incomplete promoter is developed, and a safe oral recombinant strain having no antibiotic resistant marker is constructed by multiple insertion of an optimum number of the developed gene multiple insertion cassette sets into chromosomes of a Saccharomyces cerevisiae strain. In addition, the present invention provides a vaccine composition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or nodavirus capsid protein (NNVcp) isolated and purified therefrom. In addition, the present invention provides a composition for feed addition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or squalene or oxidosqualene isolated and purified therefrom. Furthermore, the present invention provides a technique of preparing a GRAS-grade recombinant yeast strain for mass production of various recombinant proteins or useful metabolites.


Provided is a technique related to a new sensor unit which is flexible in that the sensor unit can be installed in various locations such as inside of a structure with a large curvature, and which can stably measure multi-directional deformation and very efficiently and wireless measure deformation information, and thus provided is a technique of a sensor structure which can be universally utilized in various systems for measuring deformation information. The sensor unit using an electro-active polymer for the wireless transmission/reception of deformation information, according to a first embodiment of the present invention, comprises: a first sensor part formed from a fiber or film comprising a ferroelectric electro-active polymer material; a second sensor part configured to include the first sensor part therein, and formed from a matrix comprising a dielectric elastomer electro-active polymer material; and an electrode part provided to come into contact with the first sensor part or the second sensor part and, when an external force is applied to the first sensor part or the second sensor part, transmits to the outside an electric signal generated by the first sensor part or the second sensor part.


Patent
Chung - Ang University | Date: 2016-08-11

Disclosed are stem cells having a thin multilayer structure, a method of preparing the same, and use thereof for cytotherapy. In accordance with the present invention, stem cells with a thin multilayer structure having improved stability and controlled multifunctionality are provided. A method of preparing the stem cells having the thin multilayer structure according to the present invention is very simple, and thus, the stem cells having the thin multilayer structure can be produced at low cost and high efficiency. Therefore, the stem cells having the thin multilayer structure prepared according to the present invention are very useful as a stem cell therapy agent for treating various diseases.


The present invention relates to a novel brazzein multiple variants having increased sweetness, and a production method for the same.


Patent
SK hynix and Chung - Ang University | Date: 2016-04-27

The present invention relates to an auto-focus system and method based on a sensor, using hierarchical extraction and motion estimation for an image. The auto-focus method may include the steps of: (a) extracting a phase difference image from a sensed image; (b) extracting a robust feature image which satisfies a preset reference with respect to noise and out-of-focus blur, from the phase difference image; and (C) estimating a motion vector for lens shift from the feature image.


Patent
Chung - Ang University | Date: 2016-03-14

A method and an apparatus for restoring a motion blurred image are disclosed. The method of restoring a motion blurred image comprises calculating a motion trajectory and a project trajectory of a camera using an embedded sensor; estimating a point spread function according to camera motion by using the motion trajectory and the project trajectory; and restoring the motion blurred image using the estimated point spread function and a spatially variant activity map.


The present invention relates to a method for manufacturing a transgenic plant producing immunogenic complex proteins and immunogenic complex proteins obtained therefrom and, more specifically, to a method for manufacturing a transgenic plant producing immunogenic complex proteins, a plant manufactured by the method, and immunogenic complex proteins obtained from the plant, wherein the method comprises the steps of: (a) manufacturing a transgenic plant expressing an antigen; (b) manufacturing a transgenic plant expressing an antibody specific to the antigen in step (a); and (c) cross-breeding the plants in steps (a) and (b) to manufacture a cross-bred plant. Immunogenic complex proteins can be mass-produced through the method for manufacturing a transgenic plant, comprising steps (a) to (c), and the transgenic plant manufactured by the method, of the present invention. Further, the immunogenic complex proteins (antigen-antibody complex) obtained from the plant have a gigantic four-dimensional structure, thereby having an excellent immune reaction boosting effect, thus exhibiting an excellent antibody producing capacity in a host animal, even without the use of an immune adjuvant.


The purpose of the present invention is to develop a cucumber fruit mottle mosaic virus vector so as to enable a study of gene function through gene silencing phenomenon in Cucurbitaceae plants, which has been difficult to study in the past, and to enable the study in fruits as well through stable expression. Furthermore, the present invention establishes a system that enables expression of a heterologous protein in plants, thereby, for the first time, providing a vector applicable to both the gene silencing phenomenon and protein expression in Cucurbtaceae plants.


Hyun S.,Chung - Ang University
Cellular and Molecular Life Sciences | Year: 2013

How animals achieve their specific body size is a fundamental, but still largely unresolved, biological question. Over the past decades, studies on the insect model system have provided some important insights into the process of body size determination and highlighted the importance of insulin/insulin-like growth factor signaling. Fat body, the Drosophila counterpart of liver and adipose tissue, senses nutrient availability and controls larval growth rate by modulating peripheral insulin signaling. Similarly, insulin-like growth factor I produced from liver and muscle promotes postnatal body growth in mammals. Organismal growth is tightly coupled with the process of sexual maturation wherein the sex steroid hormone attenuates body growth. This review summarizes some important findings from Drosophila and mammalian studies that shed light on the general mechanism of animal size determination. © 2013 Springer Basel.


Lee H.M.,Chung - Ang University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2014

We consider a decaying magnetic dark matter explaining the X-ray line at 3.55keV shown recently from XMM-Newton observations. We introduce two singlet Majorana fermions that have almost degenerate masses and fermion-portal couplings with a charged scalar of weak scale mass. In our model, an approximate Z2 symmetry gives rise to a tiny transition magnetic moment between the Majorana fermions at one loop. The heavier Majorana fermion becomes a thermal dark matter due to the sizable fermion-portal coupling to the SM charged fermions. We find the parameter space for the masses of dark matter and charged scalar and their couplings, being consistent with both the relic density and the X-ray line. Various phenomenological constraints on the model are also discussed. © 2014 The Authors.

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