Seoul, South Korea
Seoul, South Korea

Chung-Ang University is a notable private university based in Seoul.Starting as a church-run kindergarten in 1918, CAU transformed into a female school for kindergarten teachers in 1922 and was granted university status in 1953. The university claimed 2018 to be their centennial. It has 33,600 undergraduates, 5,200 graduates, 700 professors and 500 more part-time teaching staff.CAU is the first in South Korea to offer courses in Pharmacy, Business Management, Mass Communication, Advertising & Public Relations, Creative Writing, Photography, and Drama & Film Studies, and is active in Pharmacy, Media and the Arts. Wikipedia.


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Patent
Chung - Ang University | Date: 2016-08-11

Disclosed are stem cells having a thin multilayer structure, a method of preparing the same, and use thereof for cytotherapy. In accordance with the present invention, stem cells with a thin multilayer structure having improved stability and controlled multifunctionality are provided. A method of preparing the stem cells having the thin multilayer structure according to the present invention is very simple, and thus, the stem cells having the thin multilayer structure can be produced at low cost and high efficiency. Therefore, the stem cells having the thin multilayer structure prepared according to the present invention are very useful as a stem cell therapy agent for treating various diseases.


Qin S.,Chung - Ang University | Qin S.,University of Missouri
Nature neuroscience | Year: 2014

The importance of the hippocampal system for rapid learning and memory is well recognized, but its contributions to a cardinal feature of children's cognitive development-the transition from procedure-based to memory-based problem-solving strategies-are unknown. Here we show that the hippocampal system is pivotal to this strategic transition. Longitudinal functional magnetic resonance imaging (fMRI) in 7-9-year-old children revealed that the transition from use of counting to memory-based retrieval parallels increased hippocampal and decreased prefrontal-parietal engagement during arithmetic problem solving. Longitudinal improvements in retrieval-strategy use were predicted by increased hippocampal-neocortical functional connectivity. Beyond childhood, retrieval-strategy use continued to improve through adolescence into adulthood and was associated with decreased activation but more stable interproblem representations in the hippocampus. Our findings provide insights into the dynamic role of the hippocampus in the maturation of memory-based problem solving and establish a critical link between hippocampal-neocortical reorganization and children's cognitive development.


Kwon S.-H.,Chung - Ang University
Optics Express | Year: 2012

We propose a plasmonic whispering-gallery-mode cavity comprising of a dielectric disk with sub-hundred nanometer thickness sandwiched by two silver disks. By reducing radius and thickness carefully based on the investigated resonant wavelength dependencies, the surfaceplasmonpolariton cavity mode with a resonant wavelength of 1550 nm can be confined in a disk with a radius of 88 nm and a thickness of 10 nm, where the physical size of the cavity is 0.000064 λ0 3 (λ0: free space wavelength). The cavity mode has a deep subwavelength mode volume of 0.010 (λ/2n)3 and a high quality factor of 1900 at 40K, consequently, a large Purcell factor of 1.1 × 105. © 2012 Optical Society of America.


This paper presents a distributed containment control approach for uncertain nonlinear strict-feedback systems with multiple dynamic leaders under a directed graph topology where the leaders are neighbors of only a subset of the followers. The strict-feedback followers with nonparametric uncertainties are considered and the local adaptive dynamic surface controller for each follower is designed using only neighbors' information to guarantee that all followers converge to the dynamic convex hull spanned by the dynamic leaders where the derivatives of leader signals are not available to implement controllers, i.e.; the position information of leaders is only required. The function approximation technique using neural networks is employed to estimate nonlinear uncertainty terms derived from the controller design procedure for the followers. It is shown that the containment control errors converge to an adjustable neighborhood of the origin. © 2013 Published by Elsevier Ltd.


Hyun S.,Chung - Ang University
Cellular and Molecular Life Sciences | Year: 2013

How animals achieve their specific body size is a fundamental, but still largely unresolved, biological question. Over the past decades, studies on the insect model system have provided some important insights into the process of body size determination and highlighted the importance of insulin/insulin-like growth factor signaling. Fat body, the Drosophila counterpart of liver and adipose tissue, senses nutrient availability and controls larval growth rate by modulating peripheral insulin signaling. Similarly, insulin-like growth factor I produced from liver and muscle promotes postnatal body growth in mammals. Organismal growth is tightly coupled with the process of sexual maturation wherein the sex steroid hormone attenuates body growth. This review summarizes some important findings from Drosophila and mammalian studies that shed light on the general mechanism of animal size determination. © 2013 Springer Basel.


Lee H.M.,Chung - Ang University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2014

We consider a decaying magnetic dark matter explaining the X-ray line at 3.55keV shown recently from XMM-Newton observations. We introduce two singlet Majorana fermions that have almost degenerate masses and fermion-portal couplings with a charged scalar of weak scale mass. In our model, an approximate Z2 symmetry gives rise to a tiny transition magnetic moment between the Majorana fermions at one loop. The heavier Majorana fermion becomes a thermal dark matter due to the sizable fermion-portal coupling to the SM charged fermions. We find the parameter space for the masses of dark matter and charged scalar and their couplings, being consistent with both the relic density and the X-ray line. Various phenomenological constraints on the model are also discussed. © 2014 The Authors.


The present invention relates to a protein transduction domain comprising gold nanoparticles and aptamers binding to the surfaces of the gold nanoparticles. The protein transduction domain according to the present invention is expected to be useful for diagnosing or treating diseases since the protein transduction domain specifically binds to proteins, which are to be delivered by various tagged aptamers or protein-specific aptamers binding to gold nanoparticles, thereby effectively delivering the proteins into cells, can be harmless to humans by using gold nanoparticles having very little cytotoxicity, and allows easy confirmation of the intercellular position thereof by reflecting lights of various wavelengths.


Patent
Chung - Ang University | Date: 2016-02-24

A system for training beam including a transmitter forming a transmission beam using a transmission array and a receiver forming a receiving beam using a receiving array is disclosed. The transmitter transmits an identifier of a transmission training beam selected from the transmission beams using a secondary synchronization signal or a common reference signal, etc. The identifier of the transmission training beam is used for the beam training.


The present invention relates to a pharmaceutical composition for preventing or treating ovary granulosa cell tumors containing, as an active ingredient, one selected from the group consisting of a compound represented by chemical formula 1, a pharmaceutically acceptable salt of the compound represented by chemical formula 1, a compound represented by chemical formula 2, and a pharmaceutically acceptable salt of the compound represented by chemical formula 2, or a functional health food composition. The composition according to the present invention inhibits glycogen synthase kinase-3 beta (GSK3beta) and thus has an effect of inhibiting a phosphorylation of a serine, which is the 33rd amino acid of the forkhead box L2 (FOXL2) protein, by containing, as an active ingredient, one selected from the group consisting of the compound represented by chemical formula 1, the pharmaceutically acceptable salt of the compound represented by chemical formula 1, the compound represented by chemical formula 2, and the pharmaceutically acceptable salt of the compound represented by chemical formula 2, so that the composition can be useful as a composition for preventing or treating ovary granulosa cell tumors. Further, the composition according to the present invention is expected to be also useful as a functional health food composition.


Kwak S.,Chung - Ang University
IEEE Transactions on Industrial Electronics | Year: 2012

A four-leg-based fault-tolerant matrix converter topology is proposed, along with switching function and space vector approaches for modulation schemes, to improve the reliability of matrix converter drives. The four-leg-based fault-tolerant structure utilizes an additional redundant phase module. Based on the reconfigured hardware topology, fault-tolerant modulation strategies with both switching function and space vector approaches are developed to provide the matrix converter drives with continuous and disturbance-free operation. Pulsewidth-modulated algorithms with closed-form expressions, based on a switching function matrix, are presented to synthesize redefined output waveforms with reconfigured converter structures. Furthermore, a space-vector-based scheme using the indirect equivalent circuit with the fictitious dc link is also developed for the fault-tolerant topology after failures. Experimental results show the feasibility of the proposed four-leg-based fault-remedial approach, along with the developed modulation techniques. © 2011 IEEE.

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