Gupta S.,Luxmi Bai Institute of Dental science and Hospital |
Sandhu S.V.,Genesis Research Institute |
Bansal H.,Baba Jaswant Singh Dental College Hospital and Research Institute |
Sharma D.,Christian Dental College
Journal of Diabetes Science and Technology | Year: 2015
Background: Diabetes mellitus is a noncommunicable disease with a rising prevalence worldwide and in developing countries. The most commonly used diagnostic biofluid for detection of glucose levels is blood, but sample collection is an invasive and painful procedure. Thus, there arises a need for a noninvasive and painless technique to detect glucose levels. Aims and Objectives: The objectives of the present study were to estimate the glucose levels of saliva, to assess if any significant correlation existed between the serum and salivary glucose levels, and to correlate salivary glucose levels with regard to duration of diabetes, age, and gender. In the present study, serum and salivary glucose levels of 200 subjects (100 diabetic subjects and 100 nondiabetic subjects) were estimated by glucose oxidase method. Glycosylated hemoglobin levels were also measured in randomly selected 40 diabetic subjects. Results: The findings of present study revealed a significant correlation between salivary and serum glucose levels in both diabetic and nondiabetic subjects. No significant relationship was observed between salivary glucose levels and gender or age in both diabetics and nondiabetics and between salivary glucose levels and duration of diabetes in diabetics. Conclusion: On the basis of the findings, it was concluded that salivary glucose levels could serve as a potentially noninvasive adjunct to monitor glycemic control in diabetic patients.
Chaudhry A.,Christian Dental College |
Sidhu M.S.,Hospital and Research Institute |
Chaudhary G.,Hospital and Research Institute |
Grover S.,Hospital and Research Institute |
And 2 more authors.
American Journal of Orthodontics and Dentofacial Orthopedics | Year: 2015
Introduction The aim of this study was to evaluate the effects of a fixed functional appliance (Forsus Fatigue Resistant Device; 3M Unitek, Monrovia, Calif) on the mandible with 3-dimensional finite element stress analysis. Methods A 3-dimensional finite element model of the mandible was constructed from the images generated by cone-beam computed tomography of a patient undergoing fixed orthodontic treatment. The changes were studied with the finite element method, in the form of highest von Mises stress and maximum principal stress regions. Results More areas of stress were seen in the model of the mandible with the Forsus compared with the model of the mandible in the resting stage. Conclusions This fixed functional appliance studied by finite element model analysis caused increases in the maximum principal stress and the von Mises stress in both the cortical bone and the condylar region of the mandible by more than 2 times. © 2015 American Association of Orthodontists.
Suneja B.,BJS Dental College |
Chopra S.,Christian Dental College |
Thomas A.M.,Christian Dental College |
Pandian J.,Christian Medical College
Journal of Clinical and Diagnostic Research | Year: 2016
Introduction: Gingival overgrowth, a well-known side effect of chronic phenytoin therapy has also been known to be caused by other anti epileptic drugs (AED’s). Various factors like plaque, gingival inflammation, and periodontal health have been postulated to effect gingival overgrowth. Aim: To identify the AED having an effect on gingival overgrowth and to study the factors affecting it. Materials and Methods: Three groups of 30 children each on monotherapy of phenytoin, sodium valproate, and carbamazepine were longitudinally followed for six months. Their oral and epileptic health status was assessed and were monitored for change in plaque levels, gingival inflammation, probing depth and the status of gingival overgrowth at baseline, at the end of 3 months and finally at the end of 6 months. The data was recorded and statistically analysed. Results: Phenytoin caused gingival overgrowth in a significant number of children (53.6%) within 3 months. Sodium valproate also led to gingival overgrowth, but not upto statistically significant levels. Patients on carbamazepine did not show any signs of gingival overgrowth. Gingival overgrowth is seen more on buccal side, in the anterior segment and in the lower arch. No correlation could be found between, either plaque level, orgingival inflammation with gingival overgrowth. Probing depth could be positively correlated with gingival overgrowth. Conclusion: Phenytoin is the drug, which can be chiefly implicated for causing gingival overgrowth. Sodium valproate carries the potential for gingival overgrowth, although only up to clinically insignificant levels in 6 months. Carbamazepine can be considered a safe drug in children in relation to gingival overgrowth. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.
Philip N.I.,Mahatma Gandhi Medical College |
Prabhakar M.,Desh Bhagat Dental College |
Arora D.,Christian Dental College |
Chopra S.,Christian Dental College
American Journal of Orthodontics and Dentofacial Orthopedics | Year: 2010
Introduction: The Moyers mixed dentition space analysis method is among the most commonly used in clinical practice for detecting tooth size-arch length discrepancies. In view of reported secular trends, racial, and sex differences in tooth sizes, the purposes of this study were to evaluate the applicability of Moyers probability tables in a contemporary orthodontic population of India and to formulate more accurate mixed dentition prediction aids. Methods: Odontometric data were collected from 300 male and 300 female subjects of Indian descent, who had fully erupted mandibular permanent incisors and maxillary and mandibular canines and premolars. We measured the mesiodistal crown widths with vernier scale dial calipers. The odontometric values obtained were then subjected to statistical and linear regression analysis. Results: All tooth groups showed significant differences (P <0.001) between mesiodistal widths of male and female subjects. Regression equations for the maxillary arch (males, Y = 7.15 + 0.67X; females, Y = 7.44 + 0.65X) and the mandibular arch (males, Y = 5.55 + 0.71X; females, Y = 6.15 + 0.67X) were used to develop new probability tables on the Moyers pattern. Significant differences (P <0.05) were found between our predicted widths and the Moyers tables at almost all percentile levels, including the recommended 75% and 50% levels. Conclusions: We believe that these new prediction aids could be considered for a more precise mixed dentition space analysis in Indian children. Copyright © 2010 by the American Association of Orthodontists.
Gandhi S.,Christian Dental College |
Lata J.,Government of Punjab |
Gandhi N.,Christian Dental College
Journal of Oral and Maxillofacial Surgery | Year: 2011
Purpose: Oral lesions usually lead to a diagnostic dilemma. Fine needle aspiration cytology (FNAC) is an important diagnostic aid for making a preoperative diagnosis of oral lesions. It does not supplant histopathology but augments it. Materials and Methods: FNAC of oral lesions was undertaken in 45 patients, and all the lesions were subjected to histopathologic examination. Aspiration was performed with 23- to 25-gauge needles held in a Cameco syringe holder (Amar Udyog, Chandigarh, India). Results: We diagnosed benign lesions in 22 cases, malignant lesions in 15, and inflammatory lesions in 7 by FNAC, whereas in 1 case the specimen was insufficient for diagnosis. One result was false negative, but there was no false-positive result. Specificity and sensitivity of FNAC were 95.45% and 93.75%, respectively. FNAC gave a diagnostic accuracy of 90.0% for benign lesions, 94.0% for malignant lesions, and 100% for inflammatory lesions. Conclusion: The procedure does not have any side effects or complications. Hence FNAC can be used as a reliable diagnostic aid for oral lesions because it is safe, accurate, convenient, and cost-effective. © 2011 American Association of Oral and Maxillofacial Surgeons.