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Sun X.,University of Sichuan | Zhou X.,University of Sichuan | Ke B.,University of Sichuan | Song H.,University of Sichuan | And 4 more authors.
Synthetic Communications | Year: 2011

A practical and efficient asymmetric synthesis of the key precursor furanose 3 for the synthesis of K252a and CEP-701 has been achieved in nine steps with an overall yield of 12.8% from (R)-methyl-hydroxytetradecanoate 5, an industrial intermediate for production of orlistat. Copyright © 2011 Taylor & Francis Group, LLC.


Patent
Chongqing Zen Pharmaceutical Co. | Date: 2011-05-06

This invention discloses a novel compound with the structure of formula I, or pharmaceutically acceptable salts or solvates thereof. In addition, the invention further discloses a method for preparing the compound, a pharmaceutical composition containing the compound, and use thereof in the preparation of a hypoglycemic medicament.

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