Agrawal M.,Chirayu Medical College |
Sharma P.K.,All India Institute of Medical Sciences |
Dhaneria S.P.,All India Institute of Medical Sciences
Reviews on Recent Clinical Trials | Year: 2017
Background: Antimicrobial prophylaxis should be used in circumstances where efficacy has been demonstrated and benefits outweigh the risk. Each hospital must have an antibiotic policy that is implementable and fully adhered to. Methods: A prospective observational study was conducted in 209 patients, admitted to wards of various surgical departments including surgery, obstetrics & gynaecology (O&G), otorhinolaryngology (ENT) and orthopaedics. Relevant antimicrobial use data of each patient was collected in a customized Case Record Form (CRF) from day one until patient was discharged. Results: Majority of the patients were young adults between 19-39 years of age. Preoperative antibiotics were given in 151 and postoperative antibiotics were prescribed in all. Third generation cephalosporins was the most frequently prescribed group. The selection of antibiotics by different departments varied greatly and many prescribed (n=85) two antibiotics for preoperative prophylaxis. Average duration of surgical prophylaxis was 6.25 days. In 90 patients, preoperative antibiotic was administered before 3 hours. Conclusion: Despite routine interactive academic activities, pattern of antibiotic used was not as per guidelines suggested by competent authorities. Interventions are warranted to promote the development, dissemination and adoption of evidence based antibiotic policy. The policy should be simple, clear, noncontroversial, clinically relevant and implementable. The constant monitoring with periodic audit to ensure adherence is warranted. © 2017 Bentham Science Publishers.
Verma H.,Gandhi Medical College |
Rao S.S.,Chirayu Medical College
International Journal of Pharma and Bio Sciences | Year: 2014
Atypical antipsychotics are commonly used drugs for mental disorders, so early detection of ADRs in patients treated with antipsychotics becomes necessary. This study is a longitudinal prospective observational study of ADRs of Atypical Antipsychotic drugs in patients of psychiatric illness. Information of ADRs was data based and collected from OPD. The noted ADRs were assessed by using Naranjo's probability assessment scale, and WHO (UMC) causality assessment scale. We recorded 104 ADRs due to atypical antipsychotics. Majority of patients in this study belonged to 21-30 years age group which was 24% of the total. According to the severity of ADRs, majority of cases were reported of having weight gain 38.46% followed by sedation 19.23%, dry mouth 13.46% and orthostatic hypotension 5.76% . 88.47% were reported as type A and 11.53% were reported as type B. Definite (certain) relationship was established in 30.40% patients while probable in 57.62% and 11.53% ADRs were categorized as possible. The ADRs can be prevented by collecting reliable information about their frequencies and possible risk factors.
Patil S.B.,Chirayu Medical College |
Doibale M.K.,Dr Science Government Medical College
Online Journal of Health and Allied Sciences | Year: 2013
Objectives: To study the profile of Anganwadi Workers (AWWs). To assess knowledge of AWWs&problems faced by them while working. Study Design: Cross sectional study. Methods: Anganwadi centres were selected by stratified sampling technique. From each block 10% AWWs were enrolled into study. The functioning of AWWs was assessed by interviewing Anganwadi workers for their literacy status, years of experience, their knowledge about the services rendered by them and problems faced by them. Result: Most of AWWs were from the age group of between 41-50 years; more than half of them were matriculate and 34(69.38%) workers had an experience of more than 10 years. Majority (81.63 %) of AWWs had a knowledge assessment score of above 50%. They had best knowledge about nutrition and health education (70%). Of the workers 87.7% complained of inadequate honorarium, 28.5% complained of lack of help from community and other problems reported were infrastructure related supply, excessive work overload and record maintenance. Conclusions: Majority of AWWs were beyond 40 years of age, matriculate, experienced, having more than 50% of knowledge related to their job. Complaints mentioned by them were chiefly honorarium related and excessive workload.
Khadse J.,Medical Officer |
Bhardwaj S.D.,Chirayu Medical College |
Ruikar M.,VN Medical College
Online Journal of Health and Allied Sciences | Year: 2011
Objectives: To assess knowledge, diagnostic and treatment practices of the referring private practitioners of Nagpur city regarding Revised National Tuberculosis Control Programme (RNTCP). Methods: The study involved interview of 103 Private Practitioners (PPs) of Nagpur city. Knowledge of private practitioners was assessed based on questions related to diagnosis, categorization, treatment regimens & follow up. Practices of private practitioners were assessed based on which investigations and treatment regimen they advise & whether they offer supervised treatment. Their willingness to get involved in the programme was also recorded. Results: Only 49 (47.6%) private practitioners knew sputum smear examination as primary tool of diagnosis of TB. Only half, 52 (50.5%) of the private practitioners knew number of categories of tuberculosis correctly and 64 (62.1%) private practitioners did know how to categorize TB patients. Chest X-ray and Mantoux test (38.5%) was mainly used by the PPs for TB diagnosis. 42.7% of PPs were prescribing treatment for TB and among them only 8 were prescribing as per RNTCP guidelines and just one provided treatment under direct observation. Different combination of HRZE and HRZES was prescribed for variable period ranges from 2-8 months. And only 12 (11.6%) private practitioners expressed their willingness to get involved in RNTCP for TB control. Conclusion: There is lack of adequate knowledge, diagnostic and treatment practice among PPs as per RNTCP guidelines and further encouragement is required for their participation in the programme.
Bharosay A.,Sri Aurobindo Institute of Medical science |
Bharosay V.V.,Sri Aurobindo Institute of Medical science |
Varma M.,Sri Aurobindo Institute of Medical science |
Saxena K.,Chirayu Medical College |
And 2 more authors.
Indian Journal of Clinical Biochemistry | Year: 2012
Stroke is the third major cause of death and foremost cause of disability worldwide. Cerebrovascular stroke remains largely a clinical diagnosis. The use of biomarkers in diagnosing stroke and assessing prognosis is an emerging and rapidly evolving field. The study aimed to investigate the predictive value of neurobiochemical marker of brain damage (neuron-specific enolase [NSE]) with respect to degree of disability at the time of admission and neurological worsening in acute ischemic stroke patients. We investigated 150 patients with cerebrovascular stroke who were admitted within 72 h of onset of stroke in the Department of Neurology at SAIMS. Venous blood samples were taken after admission and NSE was analyzed by solid enzyme linked immunosorbent assay using Analyzer and microplate reader from Biored: Code 680. In all patients, the neurological status was evaluated by a standardized neurological examination and the National Institutes of Health Stroke Scale on admission and on day 7. Serum NSE concentration was found to significantly correlate with both degree of disability and neurological worsening in acute ischemic stroke cases in the present study. The maximum serum NSE level within 72 h of admission was significantly higher in patients with greater degree of disability at the time of admission. Serum NSE levels were also found to be significantly elevated in patients with bad neurological outcome. Our study showed that serum NSE has high predictive value for determining severity and early neurobehavioral outcome after acute stroke. © 2012 Association of Clinical Biochemists of India.
Arora P.,Chirayu Medical College |
Srivastava A.K.,Subharti Medical College
Journal of Indian Academy of Forensic Medicine | Year: 2013
Even in the present era of women empowerment and liberalization, a rapid increase in crimes against women is a matter of great social concern. Women are victims of iniquity not only outside but inside home too. In this study epidemiology of deaths among newly married females was explored. Most of the victims were young adults in their early married years. Most of them were housewives of joint Hindu families of middle socio-economic class, where husbands were addicted to one or the other inebriant. Educated and employed women were least affected. Ill treatment by in-laws, rash and negligent behaviour of husbands led to stressful married lives and ill mental health of wives, though most of the victims were otherwise mentally normal. All except one incidents occurred in arranged marriage. Dowry and infidelity were the most common reasons behind such deaths.
Gupta R.,Chirayu Medical College
International Journal of Pharma and Bio Sciences | Year: 2015
To study the drug prescribing pattern in Intensive Care Unit (ICU) in a tertiary care teaching hospital in central India. It was a retrospective and observational study,conducted during the period of September 2014 to February 2015. Data was obtained through the prescription record of 146 patients admitted in the Medical ICUfrom Medical Record Department of the hospital. Data was analyzed for- Most common causes for admission to ICU, male and female admission ratio, average number of drugs prescribed per prescription, Outcome of the patients, percentage usage of various antimicrobial groups. Most common cause for admission in ICU was found to be Myocardial Infarction (MI) followedby angina. In all diseases number of male patients was found to be more than female patients. Average no of drugs perpatients was found to be 7.82, Improvement was seen in 87.23% patients and mortality was seen in 2.23% patients. While condition remained same in 10.54% patients at the time of discharge. Cephalosporins were the most commonlyprescribed antimicrobial group (65.33%) followed by aminoglycosides.
Gupta R.,Chirayu Medical College
International Journal of Pharma and Bio Sciences | Year: 2015
Myristica fragrans (Nutmeg) had been reported to have various effects on different organs. This work was therefore conducted to evaluate the antidiarrheal and sedative effects of Myristica fragrans (Nutmeg) an herbal medicine in albino rats. The antidiarrheal effect of Myristica fragrans evaluated by the comparison of total count of feces discharged during 5 hours after castor oil administration in different groups of albino rats. The sedative effect of Myristica fragrans evaluated by the observation of righting reflex and the duration of hypnosis after administration of pentobarbitone in different groups of albino rats. The results of our study indicate that Nutmeg have antidiarrhoeal and some sedative effects.
PubMed | Government Medical College and Chirayu Medical College
Type: Journal Article | Journal: Journal of forensic dental sciences | Year: 2015
Identification of sex from skeletal remains is one of the important forensic considerations. Discriminant function analysis is increasingly used to determine the sex from skeleton.To develop discriminant function to determine sex from mandible in a Central Indian population.This was a prospective study done at the Department of Anatomy.The mandibles used in the present study were from the museum specimens. Only 82 adult mandibles (55 male and 27 female) that had been preserved were selected. Ten mandibular parameters were measured.Statistical analysis was conducted using Statistical Package for Social Sciences (SPSS) for Windows, version 16. The level of statistical significance was set at P < 0.05.Using stepwise discriminant function analysis, only six variables were selected as the best discriminant between sexes, with the projection length of corpus mandibulae being the most dimorphic. It was observed that sex classification accuracy of the discriminant functions ranged from 57.3 to 80.5% for the individual variables, 81.7% for the stepwise method, and 85.4% for the direct method.The results of the study show that mandibles can be used for determining sex and the results are comparable with other similar studies. The studied mandibular variables showed sexual dimorphism with an accuracy comparable with other skeletal remains, next to cranium and pelvis.
PubMed | Chirayu Medical College
Type: | Journal: Reviews on recent clinical trials | Year: 2016
Antimicrobial prophylaxis should be used in circumstances where efficacy has been demonstrated and benefits outweigh the risk. Each hospital must have an antibiotic policy that is implementable and fully adhered to.A prospective observational study was conducted in 209 patients, admitted to swards of various surgical departments including surgery, obstetrics & gynaecology (O&G), otorhinolaryngology (ENT) and orthopaedics. Relevant antimicrobial use data of each patient was collected in a customized Case Record Form (CRF) from day one until patient was discharged.Majority of the patients were young adults between 19-39 years of age. Preoperative antibiotics were given in 151 and postoperative antibiotics were prescribed in all. Third generation cephalosporins was the most frequently prescribed group. The selection of antibiotics by different department varied greatly and many prescribed (n=85) two antibiotics for preoperative prophylaxis. Average duration of surgical prophylaxis was 6.25 days. In 90 patients, preoperative antibiotic was administered before 3 hours.Despite routine interactive academic activities, pattern of antibiotic used was not as per guidelines suggested by competent authorities. Interventions are warranted to promote the development, dissemination and adoption of evidence based antibiotic policy. The policy should be simple, clear, non-controversial, clinically relevant and implementable. The constant monitoring with periodic audit to ensure adherence is warranted.