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Guo Y.,Kunming Medical University | Leng H.,Kunming Medical University | Leng H.,Yunnan Academy of Tobacco Science | Yang G.,Yunnan Academy of Tobacco Science | And 3 more authors.
Asian Journal of Chemistry | Year: 2013

A new furanoflavone, cordifoliketone C (1), together with three known furanoflavones (2-4), were isolated from the roots of Codonopsis cordifolioidea. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compounds 1-4 were tested for their anti-HIV-1 activity and antitobacco mosaic virus activity, respectively. The results showed that compounds 1-4 have modest anti-HIV-1 activity and anti-tobacco mosaic virus activity, respectively. Source


Tan J.,Yunnan Academy of Tobacco Science | Tan J.,Yunnan University | Chen Z.,Yunnan Academy of Tobacco Science | Chen Z.,China Tobacco Yunnan Industry Co. | And 5 more authors.
Heterocycles | Year: 2011

Two new benzofuranylpropanoids, nicotfurans A and B (1 - 2), were isolated from the roots and stems of Nicotiana tabacum. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D- NMR techniques. Compounds 1 - 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 - 2 have high anti-TMV activities. © 2011 The Japan Institute of Heterocyclic Chemistry. Source


Chen Z.,Yunnan Academy of Tobacco Science | Chen Z.,China Tobacco Yunnan Industry Co. | Tan J.,Yunnan Academy of Tobacco Science | Tan J.,Yunnan University | And 5 more authors.
Phytochemistry Letters | Year: 2012

Two new isoflavones, 7-hydroxy-6,3′,4′,5′-tetramethoxy- isoflavone (1) and 6-hydroxy-7,3′,4′,5′-tetramethoxy- isoflavone (2), together with seven known isoflavones were isolated from the roots and stems of Nicotiana tabacum. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidences. The anti-tobacco mosaic virus (anti-TMV) activities of the isoflavones were also evaluated. The results reveal that compound 9 shows high anti-TMV activity, compound 2 shows moderate anti-TMV activity, and compounds 1, 3-8 show weak anti-TMV activities. © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. Source


Zhou M.,Yunnan University | Zhou M.,China Tobacco Yunnan Industry Co. | Zhou K.,Yunnan University | Lou J.,Yunnan University | And 8 more authors.
Phytochemistry Letters | Year: 2015

With the aim of searching for new bioactive metabolites from medicinal plants, three new biphenyls, tababiphenyls G-I (1-3), together with four known ones (4-7) were isolated from the leaves of Nicotiana tabacum. Their structures were elucidated by extensive NMR and MS spectroscopic analyses. All the isolated compounds were evaluated for their cytotoxicity against NB4, A549, SHSY5Y, PC3, and MCF7 human cancer cell lines, and some of them showed moderate inhibitory activities against several human tumor cell lines with IC50 values ranging from 2.8 to 9.4 μM. © 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. Source


Jiang W.,Yunnan University | Zhu D.-L.,China Tobacco Yunnan Industry Co. | Wang M.-F.,China Tobacco Yunnan Industry Co. | Yang Q.-S.,Yunnan University | And 3 more authors.
Natural Product Research | Year: 2015

Two new xanthones (1–2), together with four known ones (3–6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1–6 showed weak anti-TMV activities with inhibition rate in the range of 15.2–28.8% at the concentration of 20 μM. © 2015 Taylor & Francis Source

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