China Tobacco Yunnan Industry Co.

Kunming, China

China Tobacco Yunnan Industry Co.

Kunming, China
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Zhou M.,Yunnan University | Zhou M.,China Tobacco Yunnan Industry Co. | Xing H.-H.,Yunnan University | Yang Y.,Yunnan University | And 8 more authors.
Journal of Asian Natural Products Research | Year: 2017

Three previously unreported anthraquinones, fistulaquinones A–C (1–3), together with three known ones (4–6) were isolated from the twigs of Cassia fistula. Their structures were determined by means of extensive NMR and MS spectroscopic analyses. All the isolated compounds were tested for their anti-tobacco mosaic virus (anti-TMV) activity, and compound 3 showed significant activity with inhibition rate of 34.5% at 20 μM concentration, even more potent than positive control. Additionally, compounds 1–6 exhibited moderate cytotoxicity with IC50 values ranging from 2.8 to 9.4 μM for some tested human tumor cell lines. © 2017 Informa UK Limited, trading as Taylor & Francis Group


Guo Y.,Kunming Medical University | Leng H.,Kunming Medical University | Leng H.,Yunnan Academy of Tobacco Science | Yang G.,Yunnan Academy of Tobacco Science | And 3 more authors.
Asian Journal of Chemistry | Year: 2013

A new furanoflavone, cordifoliketone C (1), together with three known furanoflavones (2-4), were isolated from the roots of Codonopsis cordifolioidea. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compounds 1-4 were tested for their anti-HIV-1 activity and antitobacco mosaic virus activity, respectively. The results showed that compounds 1-4 have modest anti-HIV-1 activity and anti-tobacco mosaic virus activity, respectively.


Tan J.,Yunnan Academy of Tobacco Science | Tan J.,Yunnan University | Chen Z.,Yunnan Academy of Tobacco Science | Chen Z.,China Tobacco Yunnan Industry Co. | And 5 more authors.
Heterocycles | Year: 2011

Two new benzofuranylpropanoids, nicotfurans A and B (1 - 2), were isolated from the roots and stems of Nicotiana tabacum. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D- NMR techniques. Compounds 1 - 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 - 2 have high anti-TMV activities. © 2011 The Japan Institute of Heterocyclic Chemistry.


Chen Z.,Yunnan Academy of Tobacco Science | Chen Z.,China Tobacco Yunnan Industry Co. | Tan J.,Yunnan Academy of Tobacco Science | Tan J.,Yunnan University | And 5 more authors.
Phytochemistry Letters | Year: 2012

Two new isoflavones, 7-hydroxy-6,3′,4′,5′-tetramethoxy- isoflavone (1) and 6-hydroxy-7,3′,4′,5′-tetramethoxy- isoflavone (2), together with seven known isoflavones were isolated from the roots and stems of Nicotiana tabacum. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidences. The anti-tobacco mosaic virus (anti-TMV) activities of the isoflavones were also evaluated. The results reveal that compound 9 shows high anti-TMV activity, compound 2 shows moderate anti-TMV activity, and compounds 1, 3-8 show weak anti-TMV activities. © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.


Jiang W.,Yunnan University | Zhu D.-L.,China Tobacco Yunnan Industry Co. | Wang M.-F.,China Tobacco Yunnan Industry Co. | Yang Q.-S.,Yunnan University | And 3 more authors.
Natural Product Research | Year: 2015

Two new xanthones (1–2), together with four known ones (3–6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1–6 showed weak anti-TMV activities with inhibition rate in the range of 15.2–28.8% at the concentration of 20 μM. © 2015 Taylor & Francis


Li Y.,Southwest University | Li Y.,China Tobacco Yunnan Industry Co. | Zhao Y.,China Tobacco Yunnan Industry Co. | Xiang N.,China Tobacco Yunnan Industry Co. | And 4 more authors.
Heterocycles | Year: 2014

Three new flavonoids, 8-formyl-4′-hydroxy-7-methoxy-6-methyl-flavone (1), 8-formyl-4′,7-dimethoxy-6-methylflavone (2), 4′,6-dihydroxy-7-methoxy-8-methoxycarbonylflavone (3) together with two known flavonoids (4 and 5) were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HRESIMS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1-3 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1-3 exhibited inhibition rates (%) of 18.4, 22.1 and 16.4, respectively. © 2014 The Japan Institute of Heterocyclic Chemistry.


PubMed | Yunnan University and China Tobacco Yunnan Industry Co.
Type: Journal Article | Journal: Journal of Asian natural products research | Year: 2015

Two new flavones, siameflavones A and B (1 and 2), together with five known flavones (3-7) were isolated from the stem of Cassia siamea. Their structures were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-5 were evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1-5 showed weak anti-TMV activity with inhibition rates in the range of 11.6-18.5%.


PubMed | Yunnan University and China Tobacco Yunnan Industry Co.
Type: Journal Article | Journal: Journal of Asian natural products research | Year: 2016

Phytochemical investigations on the ethanol extract of the twigs of Garcinia tetralata resulted in the isolation of three new biphenyls, tetralatabiphenyls A-C (1-3), along with three known biphenyl derivatives (4-6). Structural elucidations of 1-3 were performed by spectroscopic methods such as 1D and 2D NMR spectra, in addition to high-resolution mass spectra. Compounds 1-6 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 showed high anti-TMV activity with inhibition rate of 31.1%. Compounds 1, 2, and 4-6 also showed modest anti-TMV activities with inhibition rates in the range of 18.9-24.5%, respectively.


PubMed | Yunnan University and China Tobacco Yunnan Industry Co.
Type: Journal Article | Journal: Natural product research | Year: 2016

Two new xanthones (1-2), together with four known ones (3-6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1-6 showed weak anti-TMV activities with inhibition rate in the range of 15.2-28.8% at the concentration of 20M.


PubMed | Yunnan University and China Tobacco Yunnan Industry Co.
Type: Journal Article | Journal: Planta medica | Year: 2016

Oryzaeins A-D (1-4), four new isocoumarin derivatives, along with five known ones (5-9) were isolated from solid cultures of an endophytic fungus Aspergillus oryzae. Their structures were elucidated by detailed spectroscopic analysis and by comparison with reported data of related derivatives. Among them, compounds 1 and 2 represent the first examples of isocoumarins possessing an unusual 2-oxopropyl group and a rare 3-hydroxypropyl group. Compounds 1 and 2 displayed moderate anti-tobacco mosaic virus activities with inhibition rates of 28.4% and 30.6%, respectively, at the concentration of 20 M. The new compounds showed moderate inhibitory activities against several human tumor cell lines with IC50 values in the range of 2.8-8.8 M. Supporting information available online at http://www.thieme-connect.de/products.

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