China Biologic Products, Inc., through its indirect majority-owned subsidiary Shandong Taibang, is the only blood plasma-based biopharmaceutical company approved by the government of Shandong Province, the second largest province in China with a population of 93 million. The company is engaged in research, manufacturing, and sale of plasma-based biopharmaceutical products to hospitals and other health care facilities in China. Plasma-based human albumin is used mainly to increase blood volume while Immunoglobulin is used for disease prevention and treatment. Wikipedia.
Zhang X.,Peking Union Medical College |
Hou Y.,China West Normal University |
Ding X.,China West Normal University |
Ye S.,Peking Union Medical College |
And 6 more authors.
Preparative Biochemistry and Biotechnology | Year: 2014
Alpha1-antitrypsin is a kind of plasma protein that requires a sequence of different fractionation steps to get generally. To report an effective process for isolating and purifying alpha1-antitrypsin from Cohn Fraction IV based upon a new immunoaffinity chromatography medium, named "Alpha-1 Antitrypsin Select," characterization of alpha1-antitrypsin (α1-AT) was performed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), Western blot, and tandem mass spectroscopy. Total protein content was determined by the method of Bradford under visible light absorption at 595 nm. Pretreatment process and the immunoaffinity chromatography step achieved a 60.35±1.39% yield. Thus, an overall 71.68±1.32 fold increase in purity and a 41.88±6.98% yield were obtained from plasma. The α1-AT had a specific activity of about 1.00-1.05 PU/mg. This technique will develop an effective process for isolating and purifying, with high purity and specific activity, alpha1-antitrypsin from Cohn Fraction IV or human whole plasma, which could be an efficient and scaled-up method for alpha1-antitrypsin products purification. Copyright © Taylor & Francis Group, LLC. Source
Treatment for cell immunity deficiency diseases, viral infection and leucopenia caused by various reasons, and assist in postoperative healing. Specifications: 4ml
China Biologic Products, Inc. (NASDAQ: CBPO), is one of the largest non-state-owned fully integrated plasma-based biopharmaceutical companies in China ...