Wushan, China

South China Agricultural University commonly referred to as SCAU, is a public university in Guangzhou, China.Founded in 1909. Main campus settles in Wushan, Guangzhou, People's Republic of China. It is a national comprehensive university with long history. The university has 24 colleges/department and more than 40,000 students, including international students from 33 countries. The main feature of the university is biology science. Wikipedia.


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Grant
Agency: Cordis | Branch: FP7 | Program: CP-SICA | Phase: ENV.2007.4.1.4.2.;ENV.2007.2.1.4.3. | Award Amount: 1.91M | Year: 2009

Project partner will complete a detailed multidisciplinary situation analysis of highland aquatic resources, focused on values, livelihoods, conservation issues and wise-use options at five sites in Asia (Guangdong, China; Uttrakhand and West Bengal, India and northern and central Vietnam). Factors assessed will include biodiversity and ecosystem services, including provisioning, regulating, supporting and cultural services. Livelihood strategies of households dependent on ecosystem services derived from highland aquatic resources, in particular poor, food-insecure and vulnerable people, will be assessed within a sustainable livelihoods framework and opportunities to enhance such livelihoods assessed. Institutional features, including local, national and international policy and legislation, trajectories of change, stakeholder values associated with highland aquatic resources and areas of conflict will be assessed. Stakeholder participation will be critical to ensure new knowledge is accessible for collective decision-making and development of policies for the equitable use and conservation; methods and indicators for participatory monitoring and evaluation of ecosystem services and biodiversity will be developed. Action plans will then be formulated with stakeholders to: monitor the health of highland aquatic resources; develop and promote wise-use, and where necessary livelihoods diversification, to enhance poor livelihoods and conservation; integrate sustainable and wise-use, livelihoods diversification and conservation with watershed management priorities throughout the region. Action plans will be implemented by stakeholders at four sites displaying high biodiversity in Asia and the ecosystem, livelihoods and institutional impacts assessed through participatory monitoring and evaluation. Best practices aimed at conserving biodiversity and sustaining ecosystem services will be communicated to potential users to promote uptake and enhanced policy formulation.


News Article | February 21, 2017
Site: cen.acs.org

Anyone who has ever been to a farm knows there’s no shortage of drool dangling from the mouths of barnyard animals. Those super-active salivary glands could someday be put to good use, according to a new study. Zhenfang Wu and colleagues at the South China Agricultural University transformed the salivary glands of mice into miniature bioreactors for producing human nerve growth factor (NGF) proteins in their spit (Sci. Rep. 2017, DOI: 10.1038/srep41270). “This is the first paper that reports production of therapeutic protein from transgenic animals’ saliva,” Wu says. Protein drugs, such as blood clotting factors and insulin, are often produced in large vats of genetically engineered cells. Sometimes yields are low, and if bacterial or yeast cells are used, the protein drugs may lack the appropriate chemical modifications that occur in mammalian cells, such as glycosylation. To get around that limitation, some scientists have turned to harvesting the proteins from transgenic animals. Two therapeutic proteins produced in in the milk of genetically modified animals, ATryn and Ruconest, have been approved for use in Europe and the U.S. In the new study, Wu’s team looked to produce NGF. Scientists have studied human NGF because of its therapeutic implications in a number of neurological diseases, including Alzheimer’s, Parkinson’s, spinal cord injury, and glaucoma. Surprisingly, NGF is produced in both mouse and human saliva, but Wu and colleagues engineered mice to produce human NGF protein in their salivary glands instead of the mouse version. To collect the NGF protein, the researchers anesthetized the mice and administered pilocarpine hydrochloride, a known salivary stimulant. After purifying NGF from the saliva, the team showed that the protein was functional, triggering rat adrenal gland cells to become neuronlike. “Currently we are working on using this process in pigs,” Wu says, adding that his team has already developed methods for “repeated, long-term and large-volume collection of saliva from pigs.” “The production of pharmaceutical proteins from transgenic animals is developing slowly. This is the case even for the production from milk, which is likely the best system,” says Louis-Marie Houdebine, an expert on producing drugs in transgenic animals at the French National Institute for Agricultural Research. Enqi Liu of the Laboratory Animal Center at Xi’an Jiaotong University School of Medicine says that compared with milk, saliva would be especially “susceptible to microbial contamination,” posing a further complication for purifying the proteins. But could scientists produce a high enough concentration of a protein and collect a large enough volume of saliva to make spit a viable option? “In theory, I think it could work,” says Karen Beauchemin, a ruminant nutrition scientist at Agriculture & Agri-Food Canada. Beauchemin says that dairy cows produce more than 200 L of saliva in a single day to buffer fermentation in the rumen, the cow’s first of four stomachs. Like humans, pigs have only one stomach. Wu says that swine produce about 15 L of saliva per day, and his team has been able to collect 3 L of spit per day from pigs, for 40 days straight, without any apparent harm to the animals. Houbedine points out that salivary glands are not the first unusual tissue researchers have attempted to tap for protein production. Other researchers have proposed to engineer bladder epithelium and male epididymis tissues for collecting therapeutic proteins in animal urine and semen, respectively. “These two systems were soon abandoned,” he says, perhaps because of low yield, and also the foreseeable difficultly in marketing such a product.


Li X.,South China Agricultural University | Yu J.,Wuhan University of Technology | Yu J.,King Abdulaziz University | Jaroniec M.,Kent State University
Chemical Society Reviews | Year: 2016

As a green and sustainable technology, semiconductor-based heterogeneous photocatalysis has received much attention in the last few decades because it has potential to solve both energy and environmental problems. To achieve efficient photocatalysts, various hierarchical semiconductors have been designed and fabricated at the micro/nanometer scale in recent years. This review presents a critical appraisal of fabrication methods, growth mechanisms and applications of advanced hierarchical photocatalysts. Especially, the different synthesis strategies such as two-step templating, in situ template-sacrificial dissolution, self-templating method, in situ template-free assembly, chemically induced self-transformation and post-synthesis treatment are highlighted. Finally, some important applications including photocatalytic degradation of pollutants, photocatalytic H2 production and photocatalytic CO2 reduction are reviewed. A thorough assessment of the progress made in photocatalysis may open new opportunities in designing highly effective hierarchical photocatalysts for advanced applications ranging from thermal catalysis, separation and purification processes to solar cells. © 2016 The Royal Society of Chemistry.


Chen L.,State Key Laboratory for Conservation and Utilization of Subtropical Agro Bioresources | Chen L.,Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms | Chen L.,South China Agricultural University | Liu Y.-G.,State Key Laboratory for Conservation and Utilization of Subtropical Agro Bioresources | And 2 more authors.
Annual Review of Plant Biology | Year: 2014

In plants, male sterility can be caused either by mitochondrial genes with coupled nuclear genes or by nuclear genes alone; the resulting conditions are known as cytoplasmic male sterility (CMS) and genic male sterility (GMS), respectively. CMS and GMS facilitate hybrid seed production for many crops and thus allow breeders to harness yield gains associated with hybrid vigor (heterosis). In CMS, layers of interaction between mitochondrial and nuclear genes control its male specificity, occurrence, and restoration of fertility. Environment-sensitive GMS (EGMS) mutants may involve epigenetic control by noncoding RNAs and can revert to fertility under different growth conditions, making them useful breeding materials in the hybrid seed industry. Here, we review recent research on CMS and EGMS systems in crops, summarize general models of male sterility and fertility restoration, and discuss the evolutionary significance of these reproductive systems. Copyright © 2014 by Annual Reviews.


Patent
Zhaoqing Dahuanong Biological Medicine Co. and South China Agricultural University | Date: 2015-11-18

The invention discloses an avian infectious bronchitis virus purification method. The method uses ordinary avian embryo which was affected by avian bronchitis virus. Using the combination of centrifugation, ultrafiltration, concentration, molecular sieve chromatography and ultrafiltration method can effectively remove miscellaneous protein in embryo-derived infectious bronchitis virus antigen, high virus recovery, and have no effect on the activity of avian infectious bronchitis virus. The avian infectious bronchitis virus purified by this method can be directly used in the preparation of avian infectious bronchitis virus vaccine.


In order to elucidate the immune-protective mechanisms of inactivated Cryptocaryon irritans vaccine, different doses of C. irritans theronts were used to immunize orange-spotted grouper (Epinephelus coioides). We measured serum immobilization titer, blood leukocyte respiratory burst activity, serum alternative complement activity, and serum lysozyme activity weekly. In addition, the expression levels of immune-related genes such as interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), major histocompatibility complexes I and II (MHC I and II), and transforming growth factor-β1 (TGF-β1) were determined in spleen and gills. The results showed that the immobilization titer, respiratory burst activity, and alternative complement activity of immunized fish were significantly increased, and the levels of the last two immune parameters in the high-dose vaccine group were significantly higher than in the low-dose vaccine group. Serum lysozyme activity in the high-dose vaccine group was significantly higher than in the PBS control group. Vaccination also regulated host immune-related gene expression. For example, at 2- and 3- weeks post immunization, IL-1β expression in the high-dose vaccine group spleen was significantly increased. At 4-weeks post immunization, the fish were challenged with a lethal dose of parasite, and the survival rates of high-dose vaccine group, low-dose vaccine group, PBS control group, and adjuvant control group were 80%, 40%, 0%, and 10% respectively. These results demonstrate that inactivated C. irritans vaccination improves specific and nonspecific immune responses in fish, enhancing their anti-parasite ability. These effects are vaccine antigen dose-dependent. Copyright © 2013 Elsevier Ltd. All rights reserved.


Qi W.,South China Agricultural University
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin | Year: 2014

Human infection with a novel influenza A(H10N8) virus was first described in China in December 2013. However, the origin and genetic diversity of this virus is still poorly understood. We performed a phylogenetic analysis and coalescent analysis of two viruses from the first case of influenza A(H10N8) (A/Jiangxi-Donghu/346-1/2013 and A/Jiangxi-Donghu/346-2/2013 and a novel A(H10N8) virus (A/chicken/Jiangxi/102/2013) isolated from a live poultry market that the patient had visited. The haemagglutinin (HA), neuraminidase (NA), PA subunit of the virus polymerase complex, nucleoprotein (NP), M and nonstructural protein (NS) genes of the three virus strains shared the same genetic origins. The origins of their HA and NA genes were similar: originally from wild birds to ducks, and then to chickens. The PA, NP, M, and NS genes were similar to those of chicken influenza A(H9N2) viruses. Coalescent analyses showed that the reassortment of these genes from A(H9N2) to A(H10N8) might have occurred at least twice. However, the PB1 and PB2 genes of the chicken A(H10N8) virus most likely originated from H7-like viruses of ducks, while those of the viruses from the case most likely stemmed from A(H9N2) viruses circulating in chickens. The oseltamivir-resistance mutation, R292K (R291K in A(H10N8) numbering) in the NA protein, occurred after four days of oseltamivir treatment. It seems that A(H10N8) viruses might have become established among poultry and their genetic diversity might be much higher than what we have observed.


Situ H.,South China Agricultural University
Quantum Information Processing | Year: 2014

We present a quantum approach to play asymmetric coordination games, which are more general than symmetric coordination games such as the Battle of the Sexes game, the Chicken game and the Hawk-Dove game. Our results show that quantum entanglement can help the players to coordinate their strategies. © 2013 Springer Science+Business Media New York.


Liu M.,South China Agricultural University
Match | Year: 2010

This paper presents a simple approach to order the first Zagreb indices of connected graphs. Moreover, by the application of this simple approach, we extend the known ordering of the first Zagreb indices for some class of connected graphs.


Li C.,South China Agricultural University
Nongye Gongcheng Xuebao/Transactions of the Chinese Society of Agricultural Engineering | Year: 2012

This paper theoretically analyzes the features of hot air drying system for grain, exergy reference point, enthalpy and exergy structure of drying chamber and exergy efficiency, in order to reveal the nature of energy consumption of grain drying system. The results shows that the moisture content of grain is a state function, establishes the exergy reference point of drying system for starting calculation, proposes exergy benchmark functions and plots the changing process of moist air on its psychrometric chart. The paper also reveals the matching relation between "quantity" and "quality" by analyzing the exergy efficiency. It lays a foundation for further study of the reasons and position of energy loss. Additionally, it provides scientific analysis methods to investigate the approach and the process design of energy efficient drying system and to develop reasonable evaluation criteria for the system.

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