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Zainul Z.,Chhatrapati Shahuji Maharaj Medical University
EXCLI Journal | Year: 2011

Tobacco smoking is the common practice in a large percentage of the population worldwide, and the incidence is continuously increasing. Tobacco smoking is the most preventable cause of lung cancer, and it also impairs oral health. People are aware of the carcinogenic effects of tobacco smoking on the lungs and oral cavity, but it is also a risk factor for many other harmful diseases. This review article covers most of the diseases that are associated with tobacco smoking, such as coronary artery disease (CAD), diabetes, chronic obstructive pulmonary disease (COPD), arthritis, impotency, infertility, tuberculosis, and Alzheimer's disease. The association of these diseases with tobacco smoking is discussed in detail in this review, along with their possible pathophysiology. This article focuses on the ongoing research of these diseases, and aims to raise awareness of the hazards of tobacco smoking, and to promote antismoking awareness programs.

Kaur A.,Chhatrapati Shahuji Maharaj Medical University
Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH | Year: 2012

To analyze cases undergoing orbital exenteration in terms of demographic and socioeconomic profile of patients, indications for surgery, histopathological diagnosis and to assess the magnitude of eyelid malignancies as indication of orbital exenteration. A case record analysis of 25 patients who underwent orbital ex enteration at a tertiary care centre in India between October 2002 and October 2007 was undertaken. The case records were reviewed to obtain demographic data, presenting symptoms, duration of symptoms, laterality, best-corrected visual acuity (BCVA), and the clinical and histopathological diagnosis. The age group of patients undergoing exenteration ranged from 1 year to 78 years (Mean 46.92 +/- 10 years). Proptosis and/or a palpable mass were the main presenting complaints in 80 % of cases. The duration of symptoms was more than 5 years in 80 % cases. Primary orbital malignancies were the commonest indication for exenteration and were diagnosed in 11 cases (44 %), followed by lid malignancies in 8 cases (32 %), retinoblastoma in 4 cases (16 %) and conjunctival malignancies in 2 cases (8 %). Sebaceous gland carcinoma was the commonest lid malignancy followed by basal cell carcinoma and squamous cell carcinoma. Lid malignancies contribute the majority of the patients undergoing orbital exenteration in this part of the world, leading to an extreme sacrifice of eyes with good visual acuity. Increase in awareness, early diagnosis and prompt referral may help to overcome this grim scenario. © NEPjOPH.

Dubey P.P.,Chhatrapati Shahuji Maharaj Medical University
Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand | Year: 2011

The purpose of this study was to assess vascularity of the lunate by number of foramina and radiography of vessels of the wrist. The genesis of lunatomalacia requires some vascular risk and mechanical predisposition. The findings were correlated with the cause of Kienböck's disease. The vascular foramina were more than two in 91.33% of the lunate. The lunate had consistent dorsal and palmar branches from radial artery. The additional branches from anterior interosseous artery in 72.22% and a branch of palmar inter carpal arch in 69.44% cases contributed in arterial anastomosis on palmar aspect of lunate. The dorsal blood supply was found by anterior interosseous artery in 85.71% of specimens and dorsal branch from dorsal intercarpal arch in 50% of specimens. The blood supply of lunate comes along with various ligaments which may be disrupted due to trauma or strain leading to avascular necrosis. The present observations are suggestive of rich blood supply of lunate in comparison of other investigations. Therefore Kienböck's disease is less common in northern India.

Tikku A.P.,Chhatrapati Shahuji Maharaj Medical University
Journal of oral science | Year: 2010

This study evaluated the effectiveness of ultrasound, color Doppler imaging and conventional radiography in monitoring the post-surgical healing of periapical lesions of endodontic origin. Fifteen patients who underwent periapical surgery for endodontic pathology were randomly selected. In all patients, periapical lesions were evaluated preoperatively using ultrasound, color Doppler imaging and conventional radiography, to analyze characteristics such as size, shape and dimensions. On radiographic evaluation, dimensions were measured in the superoinferior and mesiodistal direction using image-analysis software. Ultrasound evaluation was used to measure the changes in shape and dimensions on the anteroposterior, superoinferior, and mesiodistal planes. Color Doppler imaging was used to detect the blood-flow velocity. Postoperative healing was monitored in all patients at 1 week and 6 months by using ultrasound and color Doppler imaging, together with conventional radiography. The findings were then analyzed to evaluate the effectiveness of the 3 imaging techniques. At 6 months, ultrasound and color Doppler imaging were significantly better than conventional radiography in detecting changes in the healing of hard tissue at the surgical site (P < 0.004). This study demonstrates that ultrasound and color Doppler imaging have the potential to supplement conventional radiography in monitoring the post-surgical healing of periapical lesions of endodontic origin.

Vijay S.K.,Chhatrapati Shahuji Maharaj Medical University
Echocardiography | Year: 2012

(Echocardiography 2012;29:E48-E49) Mitral annular abscess is an uncommon entity that rarely develops during the course of infective endocarditis. In this report, we present a case of a young girl who presented with acute decompensated heart failure due to acute mitral regurgitation caused by an abscess of the medial mitral annulus that perforated leading to left ventriculo-atrial fistula. This report includes echocardiographic images of this rare complication of infective endocarditis. © 2011, Wiley Periodicals, Inc.

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