Chemical Engineering College

Nanjing, China

Chemical Engineering College

Nanjing, China

Time filter

Source Type

Shi H.-B.,Chemical Engineering College | Shi H.-B.,Institute of Pharmaceutical Chemistry | Hu W.-X.,Zhejiang University of Technology | Zhang W.-M.,Institute of Pharmaceutical Chemistry | Wu Y.-F.,Institute of Pharmaceutical Chemistry
Journal of Chemical Research | Year: 2016

A series of 21 new tri- and tetra-cyclic thiosemicarbazone derivatives were prepared via the condensation of morpholine, piperazine or N-(4-methoxyphenyl)piperazine with seven methyl hydrazine-carbodithioate derivatives of 5-acetyl-2-arylamino-4-methylthiazoles under microwave irradiation. All compounds were tested for their cytotoxic activity in vitro against human gastric, lung and breast cancer cell lines. The results showed that some of the compounds displayed moderate anticancer activity. The most potent compound, a morpholinosubstituted analogue, exhibited significant activity against human breast cancer cells.

Parobek D.,University of Pittsburgh | Shenoy G.,University of Pittsburgh | Zhou F.,University of Pittsburgh | Peng Z.,University of Pittsburgh | And 3 more authors.
Journal of Chemical Education | Year: 2016

In this upper-level undergraduate experiment, students utilize micro-Raman spectroscopy to characterize graphene prepared by mechanical exfoliation and chemical vapor deposition (CVD). The mechanically exfoliated samples are prepared by the students while CVD graphene can be purchased or obtained through outside sources. Owing to the intense Raman signal of a few-layer graphene on a 300 nm thermal oxide silicon wafer, students can learn how different instrumental parameters used in Raman microscopy affect the quality of the measurement. This experiment gives students a first-hand experience in the production of a two-dimensional nanomaterial and exposes them to the utility of micro-Raman spectroscopy as a characterization technique. © 2016 The American Chemical Society and Division of Chemical Education, Inc.

Peng Z.,Chemical Engineering College | Peng Z.,University of Pittsburgh | Liu H.,University of Pittsburgh
Chemistry of Materials | Year: 2016

DNA nanostructures are ideal templates for bottom-up assembly and fabrication of nanomaterials. Their structures can be tailored for a given application and modified with pinpoint precision. They offer the best of top down and bottom up assembly. We highlight recent progress in DNA nanotechnology and in particular advances that are relevant to the materials chemistry community. Examples of using DNA nanostructure to address materials chemistry challenges are highlighted. © 2016 American Chemical Society.

Yu J.,Chemical Engineering College | Xia Y.,Chemical Engineering College | Lu M.,Chemical Engineering College
Synthetic Communications | Year: 2014

Solvent-free oxidative synthesis of benzimidazoles, benzoxazoles, and benzothiazoles from aromatic primary amines and o-phenylenediamine, o-aminophenol, and o-aminothiophenol has been achieved by using Fe(NO 3)3 and TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxyl). This reaction can use air as an economical and green oxidant, and a wide variety of derivatives were obtained in good to excellent yields. The reaction mechanism was proposed and this method provides a direct, practical, and efficient approach for the preparation of substituted benzimidazoles, benzoxazoles, and benzothiazoles. © 2014 Taylor and Francis Group, LLC.

Loading Chemical Engineering College collaborators
Loading Chemical Engineering College collaborators