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Kolkata, India

Dey A.,Presidency College | De J.N.,Charuchandra college
African Journal of Traditional, Complementary and Alternative Medicines | Year: 2012

Snakebite has been a major cause of mortality across the tropical countries including Indian subcontinent. The present review deals with the enormous amount of ethnobotanical work performed in the last few years involving use of different plants against snakebite in Indian subcontinent (India, Bangladesh, Pakistan and Nepal). From a variety of literature sources the data has been compiled mentioning the plants, parts used, dosage, mode of administration, name of the ethnic communities, geographical locations etc. depending on the availability of information. Source

Dey A.,Presidency University of India | De J.N.,Charuchandra college
Asian Pacific Journal of Tropical Disease | Year: 2012

Objective: Ethnobotanical excursions were carried out among the tribals of Purulia district, West Bengal, India to explore the traditional use of medicinal plants against fever. Methods: With the help of a semi structured questionnaire, informants were interviewed and their indigenous knowledge regarding antipyretic use of plants was documented. Results: A total number of 22 plants used as febrifuge were recorded along with their vernacular names, part(s) used, method of preparation and route of administration. Conclusions: Different tribal communities residing in the area were found to possess traditional knowledge of using phytotherapy in the treatment of fevers. © 2012 Asian Pacific Tropical Medicine Press. Source

Dey A.,Presidency College | De J.N.,Charuchandra college
Asian Journal of Plant Sciences | Year: 2010

Rauvolfia serpentina (L). Benth. ex Kurz. (Apocynaceae) has long being used in India for the treatment of snakebites and mental illness. It also controls hypertension and reduces blood pressure. The present review deals with the enormous amount of studies undertaken in different aspects of this plant in the areas of tissue culture, phytochemistry, pharmacology, molecular biology, chromosomal constituents, morpho- taxonomy, medicine and ethnobotany. © 2010 Asian Network for Scientific Information. Source

Dey A.,Presidency University of India | De J.N.,Charuchandra college
Journal of Herbal Medicine | Year: 2015

Medical herbalism has been popularized due to its reported efficacy, lesser side effects and synergistic interactions against complex syndromes. Herbal medicines are used in neurological disorders in ancient traditional systems in India, China, Japan and Korea. We retrieved and analyzed the research into anti-Huntington's neuroprotective therapeutics from plant sources investigated in neurotoxic models and transgenics in vitro and in vivo studies to provide future references for basic, pre-clinical and clinical research. The extracts, fractions and herbal compounds were summarized from popular scientific search engines and were analyzed according to their source and bioactivity. A total number of 10 plant extracts or fractions belonging to 10 species, 10 genera and 10 families, 24 active compounds and two herbal formulations were found to possess anti-HD activity via modulating a number of key signaling pathways and events implicated to HD pathogenesis. Herbal extracts/fractions and formulations exhibiting positive results in neurotoxic HD models need to be characterized for active components and underlying mechanisms of action. Plants that included Bacopa monnieri, Centella asiatica, Cannabis sativa, Gastrodia elata, Ginkgo biloba, Panax ginseng and Withania somnifera were cited as the most promising anti-HD candidates, many of which are known CNS-active drugs. Anti-HD compounds included curcumin, epigallocatechin-gallate, ginsenosides, kaempferol, naringin, resveratrol and S-allylcysteine, some of which are well known as neuroprotectants. Further research is still needed to evaluate the therapeutic efficacy of the already known as well as the novel herbal extracts and compounds in HD models. © 2015 Elsevier GmbH. All rights reserved. Source

Dey A.,Presidency University of India | Nath De J.,Charuchandra college
Journal of Herbs, Spices and Medicinal Plants | Year: 2012

Purulia, the westernmost district of West Bengal, India is inhabited by a large number of tribals. A study on ethnomedicinal plants used against snakebite in the villages of the district was carried out. Using a questionnaire, personal interviews, and conversations, 15 plant species were found to be used by the ethnic groups as anti-snake venom ousethnobotanicals. Information, mostly collected from villagers, was documented with scientific names of the plants, families, vernacular names, parts used, mode of administration, and locality of use. A note on other reports of the plants used as antivenom and their pharmacological significance were added to bridge the traditional knowledge and scientific investigations. © 2012 Copyright Taylor and Francis Group, LLC. Source

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