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Dey A.,Presidency University of India | De J.N.,Charuchandra College
Asian Pacific Journal of Tropical Disease | Year: 2012

Objective: Ethnobotanical excursions were carried out among the tribals of Purulia district, West Bengal, India to explore the traditional use of medicinal plants against fever. Methods: With the help of a semi structured questionnaire, informants were interviewed and their indigenous knowledge regarding antipyretic use of plants was documented. Results: A total number of 22 plants used as febrifuge were recorded along with their vernacular names, part(s) used, method of preparation and route of administration. Conclusions: Different tribal communities residing in the area were found to possess traditional knowledge of using phytotherapy in the treatment of fevers. © 2012 Asian Pacific Tropical Medicine Press.

Dey A.,Presidency University of India | Nath De J.,Charuchandra college
Research Journal of Botany | Year: 2011

Fungi are associated with a number of plant and human diseases. Plant extracts have been used as efficient fungicides inhibiting the growth of many fungal pathogens. Bryophytes, a small group of lower plants, evolutionarily placed between the algae and the pteridophytes, have been reported to store a number of compounds having antifungal efficacy. This review includes a list of bryophytes investigated against a number of plant and human pathogenic fungi with special reference to the compounds, nature of the compounds, name of the fungi and mode of action on the basis of available information. Bisbibenzyl was found to be the predominant antifungal active principle present in the bryophytes showing efficacy by inhibiting different types of biological activities of the pathogens. © 2011 Academic Journal Inc.

Dey A.,Presidency University of India | Nath De J.,Charuchandra College
Journal of Herbs, Spices and Medicinal Plants | Year: 2012

Purulia, the westernmost district of West Bengal, India is inhabited by a large number of tribals. A study on ethnomedicinal plants used against snakebite in the villages of the district was carried out. Using a questionnaire, personal interviews, and conversations, 15 plant species were found to be used by the ethnic groups as anti-snake venom ousethnobotanicals. Information, mostly collected from villagers, was documented with scientific names of the plants, families, vernacular names, parts used, mode of administration, and locality of use. A note on other reports of the plants used as antivenom and their pharmacological significance were added to bridge the traditional knowledge and scientific investigations. © 2012 Copyright Taylor and Francis Group, LLC.

Dey A.,Presidency University of India | De J.N.,Charuchandra College
Journal of Herbal Medicine | Year: 2015

Medical herbalism has been popularized due to its reported efficacy, lesser side effects and synergistic interactions against complex syndromes. Herbal medicines are used in neurological disorders in ancient traditional systems in India, China, Japan and Korea. We retrieved and analyzed the research into anti-Huntington's neuroprotective therapeutics from plant sources investigated in neurotoxic models and transgenics in vitro and in vivo studies to provide future references for basic, pre-clinical and clinical research. The extracts, fractions and herbal compounds were summarized from popular scientific search engines and were analyzed according to their source and bioactivity. A total number of 10 plant extracts or fractions belonging to 10 species, 10 genera and 10 families, 24 active compounds and two herbal formulations were found to possess anti-HD activity via modulating a number of key signaling pathways and events implicated to HD pathogenesis. Herbal extracts/fractions and formulations exhibiting positive results in neurotoxic HD models need to be characterized for active components and underlying mechanisms of action. Plants that included Bacopa monnieri, Centella asiatica, Cannabis sativa, Gastrodia elata, Ginkgo biloba, Panax ginseng and Withania somnifera were cited as the most promising anti-HD candidates, many of which are known CNS-active drugs. Anti-HD compounds included curcumin, epigallocatechin-gallate, ginsenosides, kaempferol, naringin, resveratrol and S-allylcysteine, some of which are well known as neuroprotectants. Further research is still needed to evaluate the therapeutic efficacy of the already known as well as the novel herbal extracts and compounds in HD models. © 2015 Elsevier GmbH. All rights reserved.

Dey A.,Presidency College | De J.N.,Charuchandra College
African Journal of Traditional, Complementary and Alternative Medicines | Year: 2012

Snakebite has been a major cause of mortality across the tropical countries including Indian subcontinent. The present review deals with the enormous amount of ethnobotanical work performed in the last few years involving use of different plants against snakebite in Indian subcontinent (India, Bangladesh, Pakistan and Nepal). From a variety of literature sources the data has been compiled mentioning the plants, parts used, dosage, mode of administration, name of the ethnic communities, geographical locations etc. depending on the availability of information.

Dey A.,Presidency College | De J.N.,Charuchandra College
Asian Journal of Plant Sciences | Year: 2011

Aristolochia indica L. (Aristolochiaceae) has long been used in Indian subcontinent in the traditional system of medicine to treat cholera, fever, bowel troubles, ulcers, leprosy, skin diseases, menstrual problems and snakebites. The plant is also used as emmenagogue, abortifacient, antineoplastic, antiseptic, anti-inflammatory, antimicrobial, antipyretic, antifertility and antispermatogenic agent. Aristolochic acid, a major active constituent of the plant is reported to cause cancer, nephropathy, sister chromatid exchange and is a potent abortifacient. The present review deals with the different scientific studies and reports available in different aspects of this plant in the areas of Morpho-taxonomy, Phytochemistry, Pharmacology, Medicoethnobotany, Tissue culture and Chromosomal study. © 2011 Asian Network for Scientific Information.

Dey A.,Presidency College | De J.N.,Charuchandra College
Asian Journal of Plant Sciences | Year: 2010

Rauvolfia serpentina (L). Benth. ex Kurz. (Apocynaceae) has long being used in India for the treatment of snakebites and mental illness. It also controls hypertension and reduces blood pressure. The present review deals with the enormous amount of studies undertaken in different aspects of this plant in the areas of tissue culture, phytochemistry, pharmacology, molecular biology, chromosomal constituents, morpho- taxonomy, medicine and ethnobotany. © 2010 Asian Network for Scientific Information.

Dey A.,Presidency College | De J.N.,Charuchandra College
Journal of Medicinal Plants Research | Year: 2011

Rauvolfia serpentina has long being used in India for the treatment of snakebites, hypertension, high blood pressure and mental illness. The present review deals with the extensive amount of work undertaken in recent years at different parts of the Indian subcontinent to explore the use of this plant in the treatment of different ailments by the tribals or the aboriginals as a part of their ethnomedical system. Different ethnic groups use this plant to treat snake, insect and animal bite, mental illness, schizophrenia, hypertension, blood pressure, gastrointestinal diseases, circulatory disorders, pneumonia, fever, malaria, asthma, skin diseases, scabies, eye diseases, spleen diseases, AIDS, rheumatism, body pain, veterinary diseases etc. This plant is also being used to prepare fermented food products © 2011 Academic Journals.

Dey A.,Presidency College | De Dr. J.N.,Charuchandra College
American-Eurasian Journal of Sustainable Agriculture | Year: 2010

Purulia, The westernmost district of West Bengal, is inhabited by a large number of tribals. A study on the ethnomedicinal plants of Ajodhya hill and its surrounding tribal villages was carried out. Through questionnaire, personal interviews and conversation, a total number of 56 plant species used by the aboriginals to treat different ailments of human beings and livestock were enumerated. The major ethnic groups present in this area include Santhali, Bhumijs, Mundas, Oraon, Birhor, Mal Pahariya, Kharia and Ho. During the investigation, a well developed system of ethnmedicinal practices was found to exist among the tribals. The family Fabaceae was having maximum number of medicinal plants (7) used by the tribals followed by Euphorbiaceae and Rubiaceae (4 each). The major plant part used was constituted by roots followed by leaves and stem. Gastrointestinal ailments, Fever, cough and cold related ailments, skin diseases and sexually transmitted diseases were the four major disorders treated by the use of medicinal plants in this area. 14, 10, 6 and 6 plants were found to be useful in the treatment of gastrointestinal ailments, fever, cough and cold related ailments, skin diseases and sexually transmitted diseases respectively.

Das S.,Charuchandra College
Asian Journal of Pharmaceutical and Clinical Research | Year: 2012

Consumption of diets rich in fruits, vegetables and derived food products can bring substantial health benefits. Research interest thus has increased in natural antioxidants and antimicrobials present in herbs, fruits or vegetables. Underutilized tropical fruits of India provide limitless opportunities for screening of novel drugs. Present study was aimed to understand the antimicrobial and antioxidant activities of tropical fruits Averrhoa carambola Linn. (starfruit) and Zizyphus mauritiana Lam. (jujube) fruits. The edible parts of the fruits were analyzed for different phytochemicals and phenolics, flavonoids, alkaloids and glycosides were found in all ripe and green starfruits or jujubes. Green fruits of Averrhoa carambola showed better antimicrobial activities in comparison with ripe varieties. Widest inhibition zones (14-15 mm DIZ) were seen in cases of extracts of ripe Zizyphus mauritiana against Escherichia coli and Staphylococcus aureus. Common antioxidants like Phenolics, flavonoids and ascorbate were measured. Extracts of ripe fruits contain higher amounts of flavonoids and ascorbate. Bers contain higher amount of ascorbate than starfruits. Ripe jujube or Zizyphus mauritiana extract showed strongest free radical scavenging or antioxidant activity among the tested.

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