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Wu D.C.,Charles ng Community Health Center
International Journal of Infectious Diseases | Year: 2013

It is well known that statins may cause elevation of liver enzymes, but the association of statins with hepatitis B reactivation has never been reported before. A case of hepatitis B reactivation induced by atorvastatin is reported herein. Atorvastatin not only caused significant increases in aminotransferases, but also caused ongoing viral replication by evidence of a several-log increase in hepatitis B virus. The reactivation recovered spontaneously by discontinuation of atorvastatin. The evolving concept of a double-edged sword with regard to statins in patients with hepatitis B is discussed. © 2013 International Society for Infectious Diseases.


Kwong K.,York College | Chung H.,Yeshiva University | Cheal K.,3843 Wellington Drive | Chou J.C.,Rutgers University | Chen T.,Charles ng Community Health Center
Community Mental Health Journal | Year: 2013

This study describes a culturally relevant intervention using a collaborative depression care model to integrate mental health and primary care services for depressed low income Chinese-Americans at a community health center. A total of 6,065 patients were screened for depression. Of the 341 who screened positive, 57 participated and were randomly assigned to receive either enhanced physician care with care management (32) or enhanced physician care only (25). All enrolled participants were assessed at baseline and 4 monthly follow-up visits for depression, physical and mental health functioning, and perceived stigma toward receiving depression care, to determine the impact, if any, of their mental health treatment. Both groups reported significant reduction of depressive symptoms and improved mental health functioning from baseline to follow-up assessments although there was no significant difference between the two groups. Although the study found no advantage to adding the care management component in the treatment of depression, screening and assertive treatment of immigrant Chinese Americans who tend to underutilize mental health services is important and consistent with the increased adoption of team based care models in patient centered medical homes. High refusal rates for enrollment in the study have implications for future study designs for this group. © 2013 Springer Science+Business Media, LLC.


Nguyen D.,New York University | Shibusawa T.,New York University | Chen M.T.,Charles ng Community Health Center
Clinical Social Work Journal | Year: 2012

This paper explores the history of Asian immigration to the United States, and its intersections with the mental health system. As mental health care have evolved since the 1960s from institutions to the community, public mental health services for Asian Americans have become increasingly culturally relevant. Major policy shifts, trends in immigration, and mental health practice will be presented with a focus on the Bridge Program at the Charles B. Wang Community Health Center. Integrative practice and research models that extend evidence-based knowledge to Asian American communities and practice implications are discussed. © 2011 Springer Science+Business Media, LLC.


Pollack H.J.,New York University | Kwon S.C.,New York University | Wang S.H.,Saint Barnabas Medical Center | Wang S.H.,Charles ng Community Health Center | And 2 more authors.
Cancer Epidemiology Biomarkers and Prevention | Year: 2014

Background: Hepatitis B virus (HBV) infection, the predominant cause of hepatocellular carcinoma (HCC) worldwide, disproportionately affects Asian Americans. Limited data exist on the variability and characteristics of infection that determine disease progression risk within U.S. Asian ethnic subgroups. Methods: Retrospective analyses were conducted on a large, community-based HBV screening and treatment program in New York City (NYC). From 2004 to 2008, the program enrolled 7,272 Asian-born individuals. Determinants of HBV seroprevalence were calculated and risk factors for HCC progression were compared across Asian subgroups. Results: Among newly tested individuals, 13% were HBV positive. Seroprevalence varied significantly with age, gender, education, birthplace, and family history of infection. Chinese-born individuals, particularly from the Fujian province, had the highest seroprevalence (23.2%and 33.1%, respectively). Clinical and virologic characteristics placed HBV-infected individuals at significant risk for HCC. Significant differences in HCC risk existed among Asian subgroups in bivariate analysis, including age, gender, HBV viral load, and HBeAg status. Differences in HBV genotype and family history of HCC may further HCC risk among subgroups. Conclusions: Asian immigrants in NYC have a high prevalence of HBV infection and are at significant risk of disease progression and HCC. Although heterogeneity in HBV seroprevalence was found by Asian subgroups, HCC risk among infected individuals was primarily explained by age and gender differences. Country and province of birth, age, and gender may further explain seroprevalence differences. Impact: Findings provide estimates of HBV burden in Asian ethnic subgroups and identify high-risk groups to target for screening and treatment that can prevent HCC. ©2014 AACR.


Kwong K.,City College of New York | Chung H.,Yeshiva University | Cheal K.,Biostatistician | Chou J.C.,Rutgers University | Chen T.,Charles ng Community Health Center
Journal of Social Work in Disability and Rehabilitation | Year: 2012

In this study the authors assessed the effects of disability beliefs, conceptualization and labeling of emotional disabilities, and perceived barriers on help-seeking behaviors among depressed Chinese Americans in a primary care setting. Forty-two Chinese Americans participated in semistructured interviews using established psychological measures and open-ended questions adapted from the Explanatory Model Interview Catalogue. The authors found that care utilization appears to be complicated by somatization of emotional problems, variations in causal attribution to depression, barriers to receiving mental health care, and the burden of comorbid physical conditions. Their findings highlight the importance of addressing these issues and educating patients about body-mind dialectic common to depression. © 2012 Copyright Taylor and Francis Group, LLC.

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