Chao Yang University of Technology

Taichung, Taiwan

Chao Yang University of Technology

Taichung, Taiwan

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Wang S.-S.,National Chung Hsing University | Tien Y.-C.,National Chung Hsing University | Hwang Y.-T.,National Chung Hsing University | Lin J.-F.,Chao Yang University of Technology | And 2 more authors.
2016 IEEE Asia Pacific Conference on Circuits and Systems, APCCAS 2016 | Year: 2016

Adaptive beamforming outperforms its non-adaptive counterpart in that it is capable of achieving a narrower main lobe and suppressing interference. It, however, calls for intensive computations to obtain the weighting factors. In this paper, we present an MVDR (minimum variance directionless response) based adaptive beamformer design for ultrasound imaging and implement the design in an FPGA platform. An efficient matrix inversion computing scheme, which can reduce the complexity by an order, is first developed to facilitate real time operations. Simulation results indicate the performance degradation due to this simplification measure is negligible. A linear systolic array design is further devised to support highly concurrent and pipelined computations. Finally, the design is implemented in a Xilinx Vertex XC7z045ffg900-2 FPGA platform. The working frequency can reach 98 MHz, and the MVDR coefficients can be updated every 64 clock cycles. For the entire ultrasound system, the proposed design can support a 64 lines by 512 pixels scanning at a frame rate of 20fps. © 2016 IEEE.


Hseu Y.-C.,China Medical University at Taichung | Hseu Y.-C.,Asia University, Taiwan | Lee C.-C.,Asia University, Taiwan | Chen Y.-C.,Chao Yang University of Technology | And 6 more authors.
Food and Chemical Toxicology | Year: 2014

Antrodia salmonea is well known in Taiwan as a beneficial mushroom. In the present study, we investigated the antioxidant activity of whole fermented broth (AS), filtrate (ASF), and mycelia (ASM) of A. salmonea using different antioxidant models. Furthermore, the effect of A. salmonea on AAPH-induced oxidative hemolysis of human erythrocytes and CuSO4-induced oxidative modification of human low-density lipoproteins (LDLs) was examined. We found that the AS, ASF, and ASM possess effective antioxidant activity against various oxidative systems including superoxide anion scavenging, reducing power, metal chelation, and DPPH radical scavenging. Further, AAPH-induced oxidative hemolysis in erythrocytes was prevented by AS, ASF, and ASM. Notably, AS, ASF, and ASM appear to possess powerful antioxidant activities against CuSO4-induced oxidative modification of LDL as assessed by malondialdehyde (MDA) formation, cholesterol degradation, and the relative electrophoretic mobility of oxidized LDL. It is noteworthy that AS had comparatively strong antioxidant ability compared to ASF or ASM, which is well correlated with the content of their total polyphenols. Thus, A. salmonea may exert antioxidant properties and offer protection from atherogenesis. © 2014 Elsevier Ltd.


Hseu Y.-C.,China Medical University at Taichung | Hseu Y.-C.,Asia University, Taiwan | Lee C.-C.,Asia University, Taiwan | Chen Y.-C.,Chao Yang University of Technology | And 6 more authors.
Journal of Ethnopharmacology | Year: 2014

Ethnopharmacological relevance The medicinal mushroom Antrodia salmonea has been used as a traditional Chinese medicine and has demonstrated antioxidant and anti-inflammatory effects. Materials and methods In the present study, we examined the anti-tumor activity of the fermented culture broth of Antrodia salmonea (AS) in vitro and in vivo and revealed its underlying molecular mechanism of action. Results Treatment of human promyelocytic leukemia (HL-60) cells with AS (50-150 μg/mL) significantly reduced cell viability and caused G1 arrest via the inhibition of cell-cycle regulatory proteins, including cyclin D1, CDK4, cyclin E, cyclin A, and phosphorylated retinoblastoma protein (p-Rb). Furthermore, AS treatment induced apoptosis, which was associated with DNA fragmentation, followed by a sequence of events, including intracellular ROS generation; mitochondrial dysfunction; Fas ligand activation; cytochrome c release; caspase-3, -8, -9, and PARP activation; and Bcl-2/Bax dysregulation. The results of the in vitro study suggested that AS-induced apoptosis in HL-60 cells was mediated by both the mitochondrial and death receptor pathways. Furthermore, we found that AS treatment was effective in delaying tumor incidence in HL-60 xenografted nude mice and reducing tumor burden. Conclusions To the best of our knowledge, this is the first report confirming the anti-tumor activity of this potentially beneficial mushroom against human promyelocytic leukemia. © 2013 The Authors. Published by Elsevier Ireland Ltd All rights reserved.


Lee M.Y.,Ohio State University | Teater B.,University of Bath | Greene G.J.,Ohio State University | Solovey A.D.,Solution Counseling | And 4 more authors.
Administration and Policy in Mental Health and Mental Health Services Research | Year: 2012

Systems collaboration has repeatedly been cited as a component of successful social service delivery. Through qualitative data, this study explored the process involved in inter-agency collaboration when providing Integrative Family and Systems Treatment (I-FAST) for families with severely emotionally or behaviorally disturbed children. Data were collected through a series of eight focus groups with 26 agency collaborators across 11 counties in Ohio. Data analysis revealed two emergent phenomena: the process of developing collaboration, consisting of making initial contact, a trial period and developing trust; and the key ingredients of collaboration, focusing on interpersonal and professional qualities. Implications of each theme are discussed. © 2011 Springer Science+Business Media, LLC.


Hsu C.-Y.,Chao Yang University of Technology | Tseng K.-K.,Harbin Institute of Technology | Chen S.-T.,Chao Yang University of Technology | Huang C.-H.,Buddhist Tzu Chi General Hospital | Huang C.-H.,Tzu Chi University
Journal of Nanoelectronics and Optoelectronics | Year: 2012

Dental radiographs have been extensively used in diagnosing dental diseases to help dentist for identifying victims of disasters. This study describes a flowchart of an automatic classification method for digital dental radiography. Thirty subjects were collected dental radiographs for this experiment. For each subject, there are fourteen different positions to take the X-ray images around the patient's mouth. A computer program was developed to automatically classify the fourteen classes of dental images, Upper Center Incisor (UCI), Lower Center Incisor (LCI), Upper Right Canine (URC), Upper Left Canine (ULC), Lower Right Canine (LRC), Lower Left Canine (LLC), Upper Right Premolar (URP), Upper Left Premolar (ULP), Lower Right Premolar (LRP), Lower Left Premolar (LLP), Upper Right Molar (URM), Upper Left Molar (ULM), Lower Right Molar (LRM) and Lower Left Molar (LLM). The classification method for digital dental radiography included image processing, feature computing and rule decisions for classifying. The results were compared with those of an experienced dentist. There were 420 images used to test the performance of proposed method. The accuracy of the classification is 80.5% (338/420). Copyright © 2012 American Scientific Publishers All rights reserved.


Weng Y.-C.,Hokkaido University | Fujiwara T.,Okayama University | Houng H.J.,Environmental Protection Administration | Sun C.-H.,Environmental Protection Administration | And 2 more authors.
Journal of Cleaner Production | Year: 2015

As a comparatively low-cost technology for waste treatment and disposal, landfilling has been adopted worldwide, particularly in developing countries. After one landfill is fully filled, the aftercare management turns into an important issue for municipalities, while the deposited waste is highly complex and condensed. Recent literature has indicated that landfill management plays an important role on critical issues of contemporary solid waste management, including biodiversity preservation, global warming mitigation, landfill mining and land reclamation. This study firstly made a comprehensive literature review on the existing studies in several Asia-Pacific economies, secondly conducted field surveys for the several illustrations of the aftercare management of closed landfills in Japan and Taiwan. Afterward, the findings from the literature and illustrations from the Asia-Pacific region were qualitatively summarized. Based on the results, concrete management strategies were discussed for the aftercare management of closed landfills in the context of land reclamation from important perspectives. For promoting the closed landfill management and seeking for adequate reclamation methods, the ex-post monitoring, impact assessments, and the essential cost-benefit analysis should be implemented with regard to respective reclamation type and local conditions. Using the outcomes of this study, municipalities can formulate concrete strategies to mitigate the risks and negative impacts, and to increase the benefits of landfills from a life-cycle perspective, considering the multi-stakeholders. © 2015 Elsevier Ltd. All rights reserved.


Tsui T.-S.,National Chung Hsing University | Yu S.-S.,National Chung Hsing University | Lin S.-H.,National Chung Hsing University | Lin J.-L.,National Chung Hsing University | And 2 more authors.
ISNE 2013 - IEEE International Symposium on Next-Generation Electronics 2013 | Year: 2013

Using balloon snake algorithm to get the contour in an image, the contour will stay on the inner darker place (that is in the relatively minimum energy) of the image. To solve this problem, we usually use median filter or Gaussian filter as the tool of softening brightness of the image. These two filters will blur the edges of the object, thus increase the difficulty to find the real contour of the object. Papari, Petkov and Campisi propose an algorithm (P-P-C filter) to soften the internal part of an image and strengthen the edge of the objects in the image. When we use balloon snake algorithm to process an image which relative contrast is not obvious, using P-P-C filter as the pre-process tool is still easier to identify the contour of the object of image than using median filter and Gaussian filter. In this paper, we use an example to illustrate that using P-P-C filter then use balloon snake algorithm to find the contour of an object is better than direct use balloon snake algorithm, using median filter then use balloon snake algorithm, and using Gaussian filter then use balloon snake algorithm to find the contour of an object. © 2013 IEEE.


Lin J.-F.,Chao Yang University of Technology | Sheu M.-H.,National Yunlin University of Science and Technology | Wang P.-S.,National Yunlin University of Science and Technology
IEEE Region 10 Annual International Conference, Proceedings/TENCON | Year: 2011

In this paper, a novel low power pulse-triggered flip-flop design is presented. Firstly, the pulse generation control logic, an AND function, is removed from the critical path to facilitate a faster discharge operation. A simple 2-transistor AND gate design is used to reduce the circuit complexity. Secondly, a conditional pulse enhancement technique is devised to speed up the discharge along the critical path only when needed. As a result, transistor sizes in delay inverter and pulse generation circuit can be reduced for power saving. Various post-layout simulation results based on UMC CMOS 90nm technology reveal that the proposed design features the best power-delay-product performance in seven FF designs under comparison. Its maximum power saving against rival designs is up to 38.4%. Compared with the conventional transmission gate based FF design, the average leakage power consumption is also reduced by a factor of 3.52. © 2011 IEEE.

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