Time filter

Source Type

News Article | December 7, 2016
Site: www.sciencenews.org

Clearing tropical forests may raise the risk of people being exposed to a gruesome disease called Buruli ulcer, a new study suggests. Mycobacterium ulcerans, the bacteria that cause Buruli skin lesions and bone deformities, can thrive in a wide range of wild creatures, especially tiny insects grazing on freshwater algae, says Aaron Morris, now at Imperial College London. Surveying more than 3,600 invertebrates and fish from both pristine forests and cleared land in French Guiana, Morris and colleagues found the bacteria flourishing in altered landscapes. As species are lost from once-complex food webs, there’s an intermediate zone where bacteria-friendly species thrive, Morris and colleagues propose online December 7 in Science Advances. When people push into tropical forests to build farms, roads and towns, the food web of the forest grows simpler, Morris says. Aquatic predators that once kept smaller predators and grazers in check have dwindled, the analysis suggests. This shift in the food web allows some grazers that bacteria multiply abundantly in to thrive in the environment. Thus people might face more risk of picking up the disease. (The exact routes of transmission aren’t clear, according to the U.S. Centers for Disease Control and Prevention.) Yet the relationship between forest loss and bacterial boom times isn’t a straight line, the researchers found.  As people change the landscape even more drastically toward urbanization, the niches for the bacteria-carriers appears to start shrinking again. This may mean that some of the bacteria’s favorite hosts are dwindling away, too. Other work has examined the way that landscape change affects people’s risks of catching infectious diseases, says Kate Jones of University College London, who has studied Lassa fever in Africa. Yet she cautions that recent research suggests that the interplay of infectious disease and disturbance depends strongly on the location. Some evidence has linked degraded ecosystems to rising numbers of small rodents that spread, for instance, Lyme disease. But in cases with diseases spread by monkeys and apes, their habitat needs mean they tend to be among the first animals to disappear as people take over land, taking particular disease risks with them. Just how the rise in bacteria for Buruli ulcer translates into numbers of human cases will take more study. The new study focused on the animals and landscape and did not look at human prevalence of the disease. Worldwide, some 5,000 to 6,000 new cases of Buruli ulcer are reported each year from a total of 15 countries, says the CDC. The disease is also found in at least 18 more countries not included in the statistics. Buruli ulcer can occur in temperate as well as tropical regions but is especially a risk for children and young teens in sub-Saharan Africa.


VANCOUVER, British Columbia--(BUSINESS WIRE)--lululemon athletica inc. (NASDAQ:LULU) today announced financial results for the third quarter ended October 30, 2016. For the third quarter ended October 30, 2016: The Company ended the third quarter of fiscal 2016 with $480.4 million in cash and cash equivalents compared to $403.4 million at the end of the third quarter of fiscal 2015. Inventories at the end of the third quarter of fiscal 2016 increased by 2% to $364.5 million compared to $357.8 million at the end of the third quarter of fiscal 2015. The Company ended the quarter with 389 stores. The Company also announced that its board of directors has approved a stock repurchase program for up to $100 million of its common shares in the open market at prevailing market prices. The timing and actual number of common shares to be repurchased will depend upon market conditions and other factors, in accordance with Securities and Exchange Commission requirements. The stock repurchase program is intended to create shareholder value by making opportunistic repurchases during periods of favorable market conditions. Shares may be repurchased from time to time on the open market, through block trades or otherwise. Purchases may be started or stopped at any time without prior notice depending on market conditions and other factors. Laurent Potdevin, lululemon's CEO, stated: "Our third quarter results demonstrated strong execution across all areas of our business as we delivered continued topline momentum, outperformed in gross margin and inflected meaningfully in EPS. This success is a result of our team's ongoing effort and commitment to delivering on our long term strategies." Mr. Potdevin continued: "As we entered the fourth quarter, we experienced mixed sales results that have since improved. I am inspired by the team's response and passion towards making this another successful holiday season, and I am confident that we will continue to deliver an unparalleled guest experience across all our channels and regions around the globe." For the fourth quarter of fiscal 2016, we expect net revenue to be in the range of $765 million to $785 million based on total comparable sales in the mid-single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $0.96 to $1.01 for the quarter. This guidance assumes 137.3 million diluted weighted-average shares outstanding and a 31.2% tax rate. For the full fiscal 2016, we now expect net revenue to be in the range of $2.320 billion to $2.340 billion based on total comparable sales in the mid-single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $2.18 to $2.23 for the full year, or $2.11 to $2.16 normalized for the tax and related interest adjustments made during the first three quarters of fiscal 2016. This guidance assumes 137.3 million diluted weighted-average shares outstanding and a 28.2% tax rate, or 30.9% excluding the above tax and related interest adjustments. A conference call to discuss third quarter results is scheduled for today, December 7, 2016, at 4:30 p.m. Eastern time. Those interested in participating in the call are invited to dial 1-800-319-4610 or 1-604-638-5340, if calling internationally, approximately 10 minutes prior to the start of the call. A live webcast of the conference call will be available online at: http://investor.lululemon.com/events.cfm. A replay will be made available online approximately two hours following the live call for a period of 30 days. lululemon athletica inc. (NASDAQ:LULU) is a healthy lifestyle inspired athletic apparel company for yoga, running, training, and most other sweaty pursuits, with products that create transformational experiences for people to live happy, healthy, fun lives. Setting the bar in technical fabrics and functional designs, lululemon works with yogis and athletes in local communities for continuous research and product feedback. For more information, visit www.lululemon.com. Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue, and the effective tax rate and diluted earnings per share excluding certain tax and related interest adjustments, are not United States generally accepted accounting principle ("GAAP") financial measures. A constant dollar basis assumes the average foreign exchange rates for the current period remained constant with the average foreign exchange rates for the same period of the prior year. We provide constant dollar changes in net revenue, total comparable sales, comparable store sales, and changes in direct to consumer net revenue because we use these measures to understand the underlying growth rate of net revenue excluding the impact of changes in foreign exchange rates. We believe that disclosing these measures on a constant dollar basis is useful to investors because it enables them to better understand the level of growth of our business. We disclose the effective tax rate and diluted earnings per share excluding certain tax and related interest adjustments because of their comparability to our historical information, which we believe is useful to investors. The presentation of this financial information is not intended to be considered in isolation or as a substitute for, or with greater prominence to, the financial information prepared and presented in accordance with GAAP. For more information on these non-GAAP financial measures, please see the section captioned "Reconciliation of Non-GAAP Financial Measures" included in the accompanying financial tables, which includes more detail on the GAAP financial measure that is most directly comparable to each non-GAAP financial measure, and the related reconciliations between these financial measures. This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 that involve risks, uncertainties and assumptions, such as statements regarding our future financial condition or results of operations and our prospects and strategies for future growth. In many cases, you can identify forward-looking statements by terms such as "may," "will," "should," "expects," "plans," "anticipates," "outlook," "believes," "intends," "estimates," "predicts," "potential" or the negative of these terms or other comparable terminology. These forward-looking statements are based on management's current expectations but they involve a number of risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of risks and uncertainties, which include, without limitation: our ability to maintain the value and reputation of our brand, including any negative publicity regarding our products or the production methods of our suppliers or manufacturers; the acceptability of our products to our guests, including receiving products that comply with our technical specifications and quality standards; our highly competitive market and increasing competition; our reliance on and limited control over third-party suppliers to provide fabrics for and to produce our products; an economic downturn or economic uncertainty in our key markets; increasing product costs and decreasing selling prices; our ability to anticipate consumer preferences and successfully develop and introduce new, innovative and updated products; our ability to accurately forecast customer demand for our products; our ability to safeguard against security breaches with respect to our information technology systems; any material disruption of our information systems; our ability to manage our growth and the increased complexity of our business effectively; the fluctuating costs of raw materials; our ability to expand internationally in light of our limited operating experience and limited brand recognition in new international markets; our ability to deliver our products to the market and to meet customer expectations if we have problems with our distribution system; imitation by our competitors; our ability to protect our intellectual property rights; changes in tax laws or unanticipated tax liabilities, capital or financing needs in the United States, or our intentions with respect to the reinvestment of foreign earnings; our ability to cancel store leases if an existing or new store is not profitable; increasing labor costs and other factors associated with the production of our products in South and South East Asia; our ability to successfully open new store locations in a timely manner; our ability to comply with trade and other regulations; the continued service of our senior management; seasonality; fluctuations in foreign currency exchange rates; the operations of many of our suppliers are subject to international and other risks; our ability to source our merchandise profitably or at all; our exposure to various types of litigation; actions of activist stockholders; and other risks and uncertainties set out in filings made from time to time with the United States Securities and Exchange Commission and available at www.sec.gov, including, without limitation, our most recent reports on Form 10-K and Form 10-Q. You are urged to consider these factors carefully in evaluating the forward-looking statements contained herein and are cautioned not to place undue reliance on such forward-looking statements, which are qualified in their entirety by these cautionary statements. The forward-looking statements made herein speak only as of the date of this press release and we undertake no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances, except as may be required by law. Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue The below changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue show the net change for the third quarter of fiscal 2016 compared to the third quarter of fiscal 2015. Effective tax rate and diluted earnings per share, excluding tax and related interest adjustments Expected annual effective tax rate and diluted earnings per share, excluding tax and related interest adjustments


News Article | December 6, 2016
Site: www.businesswire.com

WASHINGTON--(BUSINESS WIRE)--CEOs report higher expectations for sales and hiring over the next six months, but lower expectations for capital investment, according to the Business Roundtable fourth quarter 2016 CEO Economic Outlook Survey. For the fifth straight year, CEOs cited regulation as the top cost pressure facing their companies. In their first GDP estimate for 2017, CEOs projected 2 percent growth next year. While the outlook for hiring is positive, the overall results suggest continued economic growth, albeit at a slow pace. The Business Roundtable CEO Economic Outlook Index — a composite of CEO projections for sales and plans for capital spending and hiring over the next six months — rose by 4.6 points, from 69.6 in the third quarter to 74.2 in the fourth quarter. The Index remains below its historical average of 79.6. CEO expectations for sales over the next six months increased by 4.5 points, and expectations for hiring increased by a more robust 14.8 points over last quarter. However, CEO plans for capital expenditures fell by 5.4 points relative to last quarter. “America’s business leaders are encouraged by President-elect Trump’s pledge to boost economic growth,” said Doug Oberhelman, Chairman & CEO of Caterpillar Inc. and Chairman of Business Roundtable. “We will work with the incoming Administration and Congress to enact pro-growth policies such as modernizing the U.S. tax system, adopting a smarter approach to regulation, investing in infrastructure and focusing on the education and training people need to thrive in the 21st century economy.” In response to a question posed annually in the fourth quarter, CEOs once again reported that regulation was the top cost pressure facing their businesses, followed by labor and health care costs. “It’s telling that for the fifth year in a row CEOs name regulation as their greatest cost pressure,” said Oberhelman. “We are encouraged by the promise of a renewed focus to usher in a smarter regulatory environment that promotes job creation and economic growth and also protects safety, health and the environment.” The survey’s key findings from this quarter and the third quarter of 2016 include: The Business Roundtable CEO Economic Outlook Index — a composite index of CEO plans for the next six months of sales, capital spending and employment — increased from 69.6 in the third quarter of 2016 to 74.2 in the fourth quarter of 2016. The long-term average of the Index is 79.6. The Business Roundtable CEO Economic Outlook Survey, conducted quarterly since the fourth quarter of 2002, provides a forward-looking view of the economy by Business Roundtable member CEOs. The survey is designed to provide a picture of the future direction of the U.S. economy by asking CEOs to report their plans for their company’s sales, capex and employment in the next six months. The data are used to create the Business Roundtable CEO Economic Outlook Index and sub-indices for sales, capex and hiring expectations. All of these indices are diffusion indices that range between -50 and 150 — where readings at 50 or above indicate an economic expansion, and readings below 50 indicate an economic contraction. A diffusion index is defined as the percentage of respondents who report that a measure will increase, minus the percentage who report that the measure will decrease. The fourth quarter 2016 survey was conducted between October 26 and November 16, 2016. Responses were received from 142 member CEOs. The percentages in some categories may not equal 100 due to rounding. Results of this and all previous surveys are available at brt.org/resources/ceo-survey. Business Roundtable CEO members lead companies with more than $6 trillion in annual revenues and nearly 15 million employees. The combined market capitalization of Business Roundtable member companies is the equivalent of nearly one-quarter of total U.S. stock market capitalization, and Business Roundtable members invest $103 billion annually in research and development – equal to 30 percent of U.S. private R&D spending. Our companies pay $226 billion in dividends to shareholders and generate $412 billion in revenues for small and medium-sized businesses annually. Business Roundtable companies also make more than $7 billion a year in charitable contributions. Learn more at BRT.org


Patent
Change Inc. | Date: 2014-12-19

Provided herein are drinks (e.g., carbonated drinks) comprising one or more unsaturated fatty acids (e.g., an omega-3, omega-6, and/or omega-9) fatty acids, wherein the drinks are characterized by a low glycemic index and/or an enhanced non-refrigerated shelf life.


Patent
Change Inc. | Date: 2016-06-14

A computer-implemented method for enabling an individual to round up the monetary cost of a purchase to a specified amount and contribute the difference to a third party. More specifically, the method allows a user to round up a purchase to the nearest dollar or other amount and then contribute that change to a pool of donations, and further allows fundraising campaigns to compete for the pool of donations through various competitive, social media-based games. In some embodiments, the present invention may be incorporated directly within a digital wallet on a mobile device. In other embodiments the present invention may be a stand-alone application on a mobile device that interfaces with a digital wallet.


Trademark
Change Inc. | Date: 2016-02-29

Dietary and nutritional supplements.


Trademark
Change Inc. | Date: 2016-05-02

Computer hardware for the capturing of images and recording of video for use in a medical or surgical environment; Computer software and hardware for recording, documenting, archiving video and images; Digital video recorders; Electronic data recorders.


Trademark
Change Inc. | Date: 2016-02-23

Educational apparatus for teaching and testing knowledge on the principles of environmental protection and resource sustainability, namely, energy generation devices, resource availability and consumption display devices, water table display devices, pollution effect display devices, and animal display devices. Educational aids for teaching and testing knowledge on the principles of environmental protection and resource sustainability, namely, flash cards, maps, energy generation display models, pollution effect display models, resource availability and consumption display models, water table display models, and animal display models. Games related to environmental protection and resource sustainability, namely, card games, dice games, and board games; toys related to environmental protection and resource sustainability, namely, balls, playing cards, and energy generation device building kits. Educational services, namely, providing lesson plans, experiential education, project design and execution, training, workshops, and seminars, in the field of environmental protection and resource sustainability; Providing educational information in the field of environmental protection and resource sustainability for the purpose of academic study; Educational services, namely, providing educational information in the field of environmental protection and resource sustainability for the purpose of continuing professional education to educators, community event organizers and business operators. Environmental protection and resource sustainability consulting, namely, providing information in the field of environmental protection and natural resource sustainability.


Trademark
Change Inc. | Date: 2016-09-28

Downloadable software in the fields of network security, network behavior analytics, user behavior analytics, system behavior analytics, application behavior analytics, identity and access management, behavioral baselining and monitoring, operational behavioral analytics, maintaining the security and privacy of the network, users, systems, applications and data, and monitoring the integrity of a computer network or computer system; Software in the fields of network security, network behavior analytics, user behavior analytics, system behavior analytics, application behavior analytics, identity and access management, behavioral baselining and monitoring, operational behavioral analytics, maintaining the security and privacy of the network, users, systems, applications and data, and monitoring the integrity of a computer network or computer system. Providing temporary use of non-downloadable cloud-based software in the fields of network security, network behavior analytics, user behavior analytics, system behavior analytics, application behavior analytics, identity and access management, behavioral baselining and monitoring, operational behavioral analytics, maintaining the security and privacy of the network, users, systems, applications and data; and monitoring the integrity of a computer network or computer system; Platform as a service (PAAS) featuring computer software in the fields of network security, network behavior analytics, user behavior analytics, system behavior analytics, application behavior analytics, identity and access management, behavioral baselining and monitoring, operational behavioral analytics; maintaining the security and privacy of the network, users, systems, applications and data; and monitoring the integrity of a computer network or computer system.

Loading Change Inc. collaborators
Loading Change Inc. collaborators