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News Article | May 15, 2017
Site: en.prnasia.com

EL MONTE, Calif., May 16, 2017 /PRNewswire/ -- Yew Bio-Pharm Group, Inc. ("Yew Bio" or the "Company") (YEWB), a major grower and seller of yew trees, yew raw materials used in the manufacture of traditional Chinese medicine, handicraft products made from yew timber and yew candle and soap made with yew essence oil in China, today reported financial results for the three months ended March 31, 2017. Total revenues for the first quarter of 2017 decreased 8.6% to $7.9 million from $8.6 million a year ago. Sales of TCM raw materials amounted to 32.2% of total revenues; sales of yew trees amounted to 0% of total revenues; sales of handicrafts amounted to 0 % of total revenues and sales of "Others" segment consisting with yew candle, yew essence oil soap and pine needle extracts amounted to 67.8% of total revenues. The Company did not make sales of yew tree in the first quarter of 2017 which was mainly attributable to its strategy adjustment to reserve more yew trees for future TCM raw materials sales. For the 2017 first quarter, gross profit was $519,980, or 6.6% of total revenues, compared with $1.4 million, or 16.2% of total revenues for the comparable 2016 quarter. The decrease in the gross profit margin were primarily attributable to the lower gross margin of "Others" segments. Operating expenses decreased 5.5% to $298,403 for the quarter ended March 31, 2017, from $315,900 in the year-ago quarter. The decreasing was primarily attributable to the decreases in stock-based compensation. Net income for the three months ended March 31, 2017 decreased 83.8% to $169,904 from $1.1 million in the same quarter last year due to the decreases in revenues from TCM raw materials. Earnings per diluted share for the three months ended March 31, 2017 was $0.00 as compared to $0.02 for the same period last year. "We are pleased with the steady sales increase in Others segment," said Mr. Zhiguo Wang, Chairman and Chief Executive Officer of Yew Bio-Pharm Group. "This newly added segment had contributed a great portion of our total revenues since the second quarter of 2016. As we mentioned in prior announcement, we expected to launch some new products in the year of 2017, and we recently signed agreement to manufacture two cosmetic series products, the facial creamer and wrinkle remover, both contain yew oil as the main ingredient. We believe these new developed cosmetic products will greatly enrich our product mix and to increase our potential revenues." "We also recently established a retail store located at 1635 S. San Gabriel Blvd. #11, San Gabriel, California. The retail store is mainly focus on promoting and selling yew candles, yew oil soaps and some other yew merchandises. This is a very important milestone for the Company to explore the U.S. consumer market, as well as to promote our yew related products. Accompanied by progressive strategy towards market contact, we believe our yew series products will attract large numbers of U.S. customers in the future." Yew Bio-Pharm Group, Inc., through its operating entity, Harbin Yew Science and Technology Development Co., Ltd. (HDS), is a major grower and seller of yew trees, yew raw materials used in the manufacture of traditional Chinese medicine (TCM) and products made from yew timber in China. Raw material from the species of yew tree that the Company grows contains taxol, and TCM containing yew raw materials has been approved as a traditional Chinese medicine in China for secondary treatment of certain cancers. The Company uses a patented, accelerated growth technology to speed the growth and maturity and commercialization of yew trees and believes that it is one of the few companies possessing a permit to sell them. Yew Bio-Pharm also recently established a division to focus on organic foods and dietary supplements with the aim of developing new business opportunities in related industries. To learn more, please visit www.yewbiopharm.com This press release forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, as amended, or the Exchange Act. These forward-looking statements involve a number of risks and uncertainties that could cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by these forward-looking statements.  A number of factors could cause actual results to differ materially from those contained in any forward-looking statement, including but not limited to the following: our ability to collect from our largest customers; our dependence on a small number of customers for raw materials, including a related party; our ability to continue to purchase raw materials at relatively stable prices; our dependence on a small number of customers for our yew trees for reforestation; our ability to market successfully raw materials used in the manufacture of traditional Chinese medicines; and our ability to receive continued preferential tax treatment for the sale of yew trees and potted yew trees. From time to time, these risks, uncertainties and other factors are discussed in the Company's filings with the U.S. Securities and Exchange Commission, including its most recent annual report on Form 10-K. Yew Bio does not undertake any obligation to update any forward-looking statements as a result of new information, future events or otherwise, except as required under applicable law. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/yew-bio-pharm-group-reports-2017-first-quarter-financial-results-300457493.html


News Article | July 31, 2017
Site: www.engineeringnews.co.za

Agriculture is the largest economic growth sector for Africa, New Partnership for Africa's Development business foundation CEO Lynette Chen said at the Southern African Development Community (SADC) Industrialisation Week on Monday. She pointed out that less than 10% of arable land in Africa was farmed commercially because smallholder farmers, which made up between 70% and 80% of farmers on the continent, were not using their land as a business opportunity. She stated that one of the biggest challenges around African agricultural production was showing subsistence farmers how to become more commercially minded. “We need to support smallholder farmers by getting them into cooperatives and associations. Turning a smallholder farm into a business can contribute to food security throughout the continent, as well as support families and direct communities through agribusiness,” she said. Chen pointed out that there were good examples in the SADC region of effective and efficient farmers associations that were well organised. “In Mozambique, for example, they use two different cooperative models. One is where they form associations whereby each farmer sells produce to that association, which markets it for them.” She added that, alternatively, the farmers are all shareholders of a specific cooperative, where they work and produce under a single label. “The challenge is promoting agricultural investment in Africa, especially through the Beira corridors, which include Mozambique, Zambia and Malawi,” she said. She noted that smallholder farmers had major challenges to access land rights, which they needed to secure loans from banks. Chen said access to finance was also challenge, as agriculture was seen as a risky investment area, particularly at the microfinance level. Agriculture contributes 15% to Africa’s gross domestic product, which Chen said was nowhere near what it should be. “It needs investment by large agribusiness, which is starting to happen. A lot of Saudi and Asian companies are starting to invest in agricultural production on the continent,” she said. She stressed, however, that to ensure food security, value-added production processing has to be done in Africa, which is why the SADC industrialisation strategy is important in creating value chains. “Most of the agriculture produced on the continent is exported, and that needs to change,” she added. CLIMATE CHANGE Chen, meanwhile, pointed to last year’s drought and its severe impact on the agricultural sector in the region. “There needs to be some sort of ‘guarantee instrument’ that will support farmers during bleak times. Climate change has had a significant impact on the agricultural sector in the SADC region and we need to work with farmers to understand climate change patterns and train them to adjust their farming regimes and plans to be integrated with the changes and seasons,” she said. She added that climate change adaptation was critical and that more grassroots interaction needed to take place for a mindset change to occur. At a policy level, Chen said government had a significant role to play in understanding the challenges of climate change and putting policies in place that would support farmers financially. “The SADC has the SADC Regional Agriculture Investment Plan, which is a very comprehensive strategy. It focuses on eight key areas that need to be addressed, and is one of the most comprehensive policies on climate change I have seen,” she said.


VANCOUVER, British Columbia--(BUSINESS WIRE)--lululemon athletica inc. (NASDAQ:LULU) today announced financial results for the first quarter ended April 30, 2017 and a plan to restructure its ivivva operations. The Company reported diluted earnings per share of $0.23 for the first quarter of fiscal 2017. Excluding the impact of the ivivva restructuring, the Company reported adjusted diluted earnings per share of $0.32. The Company plans to operate ivivva, its activewear brand for girls, as a primarily e-commerce focused business, with a select number of stores in key communities across North America. It plans to close approximately 40 of its 55 ivivva branded stores and to convert approximately half of the remaining stores to lululemon branded stores. The Company will also close all of its ivivva branded showrooms and other temporary locations, and will streamline its corporate infrastructure. It is anticipated that the closures and restructuring will be substantially complete by the end of the third quarter of fiscal 2017. In connection with this restructuring plan, the Company recognized pre-tax costs totaling $17.7 million in the first quarter of fiscal 2017. The summary below provides both GAAP and adjusted non-GAAP financial measures. The adjusted financial measures exclude the impact of the ivivva restructuring plan and the related tax effects, and also exclude certain discrete tax items which were recognized during the first quarter of fiscal 2016. For the first quarter ended April 30, 2017: - Comparable store sales decreased 2%, or decreased by 1% on a constant dollar basis. - Direct to consumer net revenue was flat, and was flat on a constant dollar basis. The Company ended the first quarter of fiscal 2017 with $698.3 million in cash and cash equivalents compared to $550.0 million at the end of the first quarter of fiscal 2016. Inventories at the end of the first quarter of fiscal 2017 increased by 6% to $303.9 million compared to $286.2 million at the end of the first quarter of fiscal 2016. The Company ended the quarter with 411 stores. Laurent Potdevin, CEO, lululemon, commented: "I'm excited to see the positive trends that materialized late in Q1 continuing into Q2. Our current outlook for the remainder of 2017 is strong, and I'm energized by the growth strategies taking shape. I'm also confident in our plans to restructure ivivva and believe they are the best means to optimize this part of the business." Mr. Potdevin added: "From our cadence of product innovation, to our enhanced digital experience, and first-ever global brand campaign, we have never felt more deeply connected to our guest or better positioned to expand our collective. We remain laser focused on owning our position as the global brand defining an active, mindful lifestyle." In connection with the restructuring of the ivivva operations, we expect to recognize total pre-tax costs of between $50.0 million and $60.0 million in fiscal 2017, inclusive of $17.7 million recognized during the first quarter of fiscal 2017. This primarily relates to long-lived asset impairment and lease termination costs. For the second quarter of fiscal 2017, we expect net revenue to be in the range of $565 million to $570 million based on a total comparable sales increase in the low-to-mid single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $0.13 to $0.15 for the quarter. Excluding the impact of the ivivva restructuring, we expect adjusted diluted earnings per share to be in the range of $0.33 to $0.35 for the quarter. This guidance assumes 137.2 million diluted weighted-average shares outstanding and a 36.6% tax rate, or 31.0% excluding the tax effect of the ivivva restructuring. The guidance does not reflect potential future repurchases of the Company's shares. For the full fiscal 2017, we now expect net revenue to be in the range of $2.530 billion to $2.580 billion based on a total comparable sales increase in the low-single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $1.97 to $2.07 for the full year. Excluding the impact of the ivivva restructuring, we expect adjusted diluted earnings per share to be in the range of $2.28 to $2.38 for the year. This guidance assumes 137.2 million diluted weighted-average shares outstanding and a 31.6% tax rate, or 31.0% excluding the tax effect of the ivivva restructuring. The guidance does not reflect potential future repurchases of the Company's shares. The guidance and outlook forward-looking statements made in this press release are based on management's expectations as of the date of this press release and the Company undertakes no duty to update or to continue to provide information with respect to any forward-looking statements or risk factors, whether as a result of new information or future events or circumstances or otherwise. Actual results and the timing of events could differ materially from those anticipated in these forward-looking statements as a result of risks and uncertainties, including those stated below. A conference call to discuss first quarter results is scheduled for today, June 1, 2017, at 4:30 p.m. Eastern time. Those interested in participating in the call are invited to dial 1-800-319-4610 or 1-604-638-5340, if calling internationally, approximately 10 minutes prior to the start of the call. A live webcast of the conference call will be available online at: http://investor.lululemon.com/events.cfm. A replay will be made available online approximately two hours following the live call for a period of 30 days. lululemon athletica inc. (NASDAQ:LULU) is a healthy lifestyle inspired athletic apparel company for yoga, running, training, and most other sweaty pursuits, with products that create transformational experiences for people to live happy, healthy, fun lives. Setting the bar in technical fabrics and functional designs, lululemon works with yogis and athletes in local communities for continuous research and product feedback. For more information, visit www.lululemon.com. Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue, and the adjusted financial results, are non-GAAP financial measures. A constant dollar basis assumes the average foreign exchange rates for the period remained constant with the average foreign exchange rates for the same period of the prior year. We provide constant dollar changes in net revenue, total comparable sales, comparable store sales, and changes in direct to consumer net revenue because we use these measures to understand the underlying growth rate of net revenue excluding the impact of changes in foreign exchange rates. We believe that disclosing these measures on a constant dollar basis is useful to investors because it enables them to better understand the level of growth of our business. Adjusted gross profit, gross margin, income from operations, operating margin, effective tax rates, and diluted earnings per share exclude the costs recognized in connection with the plan to restructure the ivivva operations, its related tax effects, and certain discrete items related to the Company's transfer pricing arrangements and taxes on repatriation of foreign earnings. We believe these adjusted financial results and measures provide useful information because these items do not directly relate to our ongoing business operations and therefore do not contribute to a meaningful evaluation of the Company's future operating performance. Furthermore, we believe these adjusted financial results and metrics are useful to investors because of their comparability to our historical information. The presentation of this financial information is not intended to be considered in isolation or as a substitute for, or with greater prominence to, the financial information prepared and presented in accordance with GAAP. For more information on these non-GAAP financial measures, please see the section captioned "Reconciliation of Non-GAAP Financial Measures" included in the accompanying financial tables, which includes more detail on the GAAP financial measure that is most directly comparable to each non-GAAP financial measure, and the related reconciliations between these financial measures. This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 that involve risks, uncertainties and assumptions, such as statements regarding our future financial condition or results of operations and our prospects and strategies for future growth. In many cases, you can identify forward-looking statements by terms such as "may," "will," "should," "expects," "plans," "anticipates," "outlook," "believes," "intends," "estimates," "predicts," "potential" or the negative of these terms or other comparable terminology. These forward-looking statements also include our guidance and outlook statements. These statements are based on management's current expectations but they involve a number of risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of risks and uncertainties, which include, without limitation: our ability to maintain the value and reputation of our brand; the acceptability of our products to our guests; our highly competitive market and increasing competition; our reliance on and limited control over third-party suppliers to provide fabrics for and to produce our products; an economic downturn or economic uncertainty in our key markets; increasing product costs and decreasing selling prices; our ability to anticipate consumer preferences and successfully develop and introduce new, innovative and updated products; our ability to accurately forecast customer demand for our products; our ability to safeguard against security breaches with respect to our information technology systems; any material disruption of our information systems; our ability to have technology-based systems function effectively and grow our e-commerce business globally; the fluctuating costs of raw materials; our ability to expand internationally in light of our limited operating experience and limited brand recognition in new international markets; our ability to deliver our products to the market and to meet customer expectations if we have problems with our distribution system; imitation by our competitors; higher than anticipated costs and our ability to realize the benefits associated with the restructuring of our ivivva business; our ability to protect our intellectual property rights; changes in tax laws or unanticipated tax liabilities, capital or financing needs in the United States, or our intentions with respect to the reinvestment of foreign earnings; our ability to manage our growth and the increased complexity of our business effectively; our ability to cancel store leases if an existing or new store is not profitable; increasing labor costs and other factors associated with the production of our products in South and South East Asia; our ability to successfully open new store locations in a timely manner; our ability to source our merchandise profitably or at all; our ability to comply with trade and other regulations; the continued service of our senior management; seasonality; fluctuations in foreign currency exchange rates; the operations of many of our suppliers are subject to international and other risks; our exposure to various types of litigation; actions of activist stockholders; and other risks and uncertainties set out in filings made from time to time with the United States Securities and Exchange Commission and available at www.sec.gov, including, without limitation, our most recent reports on Form 10-K and Form 10-Q. You are urged to consider these factors carefully in evaluating the forward-looking statements contained herein and are cautioned not to place undue reliance on such forward-looking statements, which are qualified in their entirety by these cautionary statements. The forward-looking statements made herein speak only as of the date of this press release and we undertake no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances, except as may be required by law. Reconciliation of Non-GAAP Financial Measures Unaudited; Expressed in thousands, except per share amounts Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue The below changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue show the net change for the first quarter of fiscal 2017 compared to the first quarter of fiscal 2016. 2Comparable store sales reflects net revenue from company-operated stores that have been open for at least 12 months, or open for at least 12 months after being significantly expanded. The following table reconciles adjusted financial measures with the most directly comparable measures calculated in accordance with GAAP: 1 During the first quarter of fiscal 2017, we recognized costs totaling $5.4 million to reduce the carrying value of certain ivivva branded inventories to their estimated net realizable value and to record the expected net loss on certain committed inventory purchases. 2 During the first quarter of fiscal 2017, we recognized long-lived asset impairment charges of $11.6 million and severance costs of $0.7 million related to our plan to restructure our ivivva operations. 3 The adjustments in the first quarter of fiscal 2016 relate to our transfer pricing arrangements and the associated repatriation of foreign earnings. 4 The adjustment to income tax expense for the first quarter of fiscal 2017 represents the tax effect of the ivivva related restructuring adjustments, calculated based on the expected annual tax rate of the applicable tax jurisdictions. Please refer to Notes 7 and 9 to the unaudited interim consolidated financial statements included in Item 1 of Part I of our Report on Form 10-Q to be filed with the SEC on or about June 1, 2017 for further explanation as to the nature of these items. 1 These adjustments relate to our plan to restructure our ivivva operations. Please refer to Item 5 of Part II of our Report on Form 10-Q to be filed with the SEC on or about June 1, 2017 for an explanation as to the nature of these items. 1Store count and square footage summary includes company-operated stores which are branded lululemon or ivivva. Excludes retail locations operated by third parties under license and supply arrangements. 2Gross square feet added/lost during the quarter includes net square foot additions for company-operated stores which have been renovated or relocated in the quarter. 3As part of the plan to restructure its ivivva operations the Company plans on closing approximately 40 of the 55 ivivva branded company-operated stores which were in operation as at April 30, 2017, and plans on converting approximately half of the remaining stores to lululemon branded company-operated stores.


Technology Providers – Client Portals InvestEdge Connect is a turnkey client portal engineered to seamlessly connect high net worth, ultra-high net worth clients, and institutional investors with their advisors and advisory firms. The portal allows investors to view the same data their advisors use on a daily basis, and enables advisors to securely deliver critical information wherever and whenever their clients need it. Technology Providers – Portfolio Reporting The InvestEdge Client Reporting Solution equips advisors to instantaneously deliver high-quality, reliable presentations by solving many of the inefficiencies inherent with report generation and customization. The patented technology automates time-intensive tasks such as data gathering, report creation, customization, and assembly. MMxCHANGE, a new digital marketplace that enables advisory businesses to design, build, and control their own custom investment platform, has been nominated as a finalist in the following category: Technology Providers – Compliance MMxCHANGE enhances an advisor's ability to manage compliance requirements and regulations, as it affords compliance to go from reactive to proactive measures due to the level of controls offered by multi-tenant functionality. Digital Compliance Administration and Surveillance tools combined with the full control of a fiduciary, "DOL Compliant" Private Exchange, will provide compliance teams with a preemptive strategy for control. MMxCHANGE operates as a logistics center connecting advisors with the tools needed to establish a digital Fiduciary future. "At InvestEdge, we partner with wealth management businesses to provide them with the tools they need to deepen client relationships, enhance advice and move margins," said Bob Stewart, CEO of InvestEdge. "Our client reporting and portal solutions were designed with today's advisor in mind, and being named a finalist reinforces that our cutting-edge technologies are helping them deliver true value to their clients." "MMxCHANGE is designed to support any investment ecosystem no matter how simple or complex the business requirements," said Joe Miskel, Executive Vice President of MMxCHANGE. "We're pleased that WealthManagement.com is recognizing our forward-looking approach to compliance by naming us a finalist in this category." The WealthManagement.com Industry Awards recognize outstanding achievement in the Wealth Management industry. Details about the 2017 Awards and the complete list of finalists can be found on WealthManagement.com's website: http://events.wealthmanagement.com/2017-finalists/. Winners will be announced on October 11, 2017 at an awards ceremony in New York City. About InvestEdge Founded in 2000, InvestEdge, the leader in cutting-edge wealth management solutions, helps advisors deliver the ultimate client experience through integrated software for managing, measuring and reporting on high net worth and ultra-high net worth portfolios. Headquartered in Bala Cynwyd, PA, InvestEdge currently administers $1T in assets. About MMxCHANGE MMxCHANGE is a new digital marketplace that lets you design, build, and control your own custom investment platform – at a fraction of the cost of other platforms. Its unbundled open architecture allows you to select the solutions you need, when you need them, so you can always meet your clients' specific goals in a quickly changing market. This unprecedented flexibility enables you to scale your business at a lower cost. MMxCHANGE, a wholly-owned subsidiary of InvestEdge, seamlessly integrates with InvestEdge's suite of wealth management solutions and functions as a standalone solution. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/investedge-and-mmxchange-named-finalists-for-three-2017-wealthmanagementcom-industry-awards-300472309.html


Patent
Change Inc. | Date: 2017-06-21

Provided herein are carbonated beverages comprising one or more unsaturated fatty acids (e.g., an omega-3, omega-6, and/or amega-9 polyunsaturated fatty acids), wherein the beverages are characterized by having a low oxygen level of less than 500 ppb. Also provided herein are methods for preparing carbonated beverages comprising one or more unsaturated fatty acids (e.g., an omega-3, omega-6, and/or amega-9 polyunsaturated fatty acids), wherein the beverages are characterized by having a low oxygen level of less than 500 ppb.


GeNeuro (Paris:GNRO) (Euronext Paris: CH0308403085 – GNRO) and Servier announced today that 6-month data from the CHANGE-MS Phase 2b study will be presented at MSParis2017, the 7th Joint ECTRIMS-ACTRIMS meeting held 25-28 October 2017, in Paris, France. The presentation will cover efficacy and safety data, and will include post-hoc analyses supporting the hypothesis of a delayed onset of action of GNbAC1 as well as target engagement in the central nervous system. Further details will be communicated right after the conference. CHANGE-MS is an international, randomized, double-blind, placebo-controlled study of 270 RRMS patients, investigating GNbAC1 for the treatment of patients with relapsing-remitting multiple sclerosis (RRMS). GNbAC1 is a monoclonal antibody which neutralizes a retroviral envelope protein encoded by a pathogenic member of the HERV-W family (pHERV-W env). CHANGE-MS is fully funded through a partnership with Servier signed in 2014, in which Servier is involved in the development and potential commercialization of GNbAC1 in MS in territories ex USA and Japan. Under this agreement and depending on achievement of development milestones, GeNeuro could receive a maximum of €362.5M, excluding royalties. The development of GNbAC1 is the result of more than 25 years of research into human endogenous retroviruses (HERVs), including 15 years at Institut Mérieux and INSERM, a French national medical research institute. Found in the human genome, certain HERVs have been linked to various autoimmune and neurodegenerative diseases. Researchers have demonstrated that the retroviral envelope protein associated with a pathogenic form of HERV-W [pHERV-W, formerly referred to as the Multiple Sclerosis RetroVirus (MSRV)] has been identified in brain lesions of patients with MS, particularly in active lesions, and in the pancreas of T1D patients. By neutralizing pHERV-W env, GNbAC1 could at the same time block these pathological inflammatory processes and restore remyelination in MS patients and maintain insulin production in T1D patients. As pHERV-W env has no known physiological function, GNbAC1 is expected to have a good safety profile, without directly affecting the patient’s immune system, as observed in all clinical trials to date. GeNeuro‘s mission is to develop safe and effective treatments against neurological disorders and autoimmune diseases, such as multiple sclerosis and Type 1 diabetes, by neutralizing causal factors encoded by HERVs, which represent 8% of human DNA. GeNeuro is based in Geneva, Switzerland and has R&D facilities in Lyon, France. It has 30 employees and rights to 16 patent families protecting its technology. Servier is an international pharmaceutical company governed by a non-profit foundation, with its headquarters in France (Suresnes). With a strong international presence in 148 countries and a turnover of 4 billion euros in 2016, Servier employs 21,000 people worldwide. Entirely independent, the Group reinvests 25% of its turnover (excluding generic drugs) in research and development and uses all its profits for development. Corporate growth is driven by Servier’s constant search for innovation in five areas of excellence: cardiovascular, immune-inflammatory and neuropsychiatric disease, oncology and diabetes, as well as by its activities in high-quality generic drugs. Servier has a solid commitment to neuropsychiatry and to proposing innovative therapies to patients suffering from neurological conditions. Its research teams are investigating new ways of treating diseases such as Alzheimer’s and Parkinson’s, as well as a broad range of neurodegenerative disorders, by targeting the toxic proteins that lead to neuron degeneration. The priority is to focus on the causes of the diseases rather than their symptoms. Currently, there are 5 projects at different stages of research in this promising area. Regarding development, where Servier’s team has a strong expertise in international clinical development and in investigator training in neurology and psychiatry, current phase II/III projects focus on autism, major depressive disorder, post-stroke functional recovery and multiple sclerosis. This press release contains certain forward - looking statements and estimates concerning GeNeuro’s financial condition, operating results, strategy, projects and future performance and the markets in which it operates. Such forward-looking statements and estimates may be identified by words, such as “anticipate,” “believe,” “can,” “could,” “estimate,” “expect,” “intend,” “is designed to,” “may,” “might,” “plan,” “potential,” “predict,” “objective,” “should,” or the negative of these and similar expressions. They incorporate all topics that are not historical facts. Forward looking statements, forecasts and estimates are based on management’s current assumptions and assessment of risks, uncertainties and other factors, known and unknown, which were deemed to be reasonable at the time they were made but which may turn out to be incorrect. Events and outcomes are difficult to predict and depend on factors beyond the company’s control. Consequently, the actual results, financial condition, performances and/or achievements of GeNeuro or of the industry may turn out to differ materially from the future results, performances or achievements expressed or implied by these statements, forecasts and estimates. Owing to these uncertainties, no representation is made as to the correctness or fairness of these forward-looking statements, forecasts and estimates. Furthermore, forward-looking statements, forecasts and estimates speak only as of the date on which they are made, and GeNeuro undertakes no obligation to update or revise any of them, whether as a result of new information, future events or otherwise, except as required by law.


News Article | December 7, 2016
Site: www.sciencenews.org

Clearing tropical forests may raise the risk of people being exposed to a gruesome disease called Buruli ulcer, a new study suggests. Mycobacterium ulcerans, the bacteria that cause Buruli skin lesions and bone deformities, can thrive in a wide range of wild creatures, especially tiny insects grazing on freshwater algae, says Aaron Morris, now at Imperial College London. Surveying more than 3,600 invertebrates and fish from both pristine forests and cleared land in French Guiana, Morris and colleagues found the bacteria flourishing in altered landscapes. As species are lost from once-complex food webs, there’s an intermediate zone where bacteria-friendly species thrive, Morris and colleagues propose online December 7 in Science Advances. When people push into tropical forests to build farms, roads and towns, the food web of the forest grows simpler, Morris says. Aquatic predators that once kept smaller predators and grazers in check have dwindled, the analysis suggests. This shift in the food web allows some grazers that bacteria multiply abundantly in to thrive in the environment. Thus people might face more risk of picking up the disease. (The exact routes of transmission aren’t clear, according to the U.S. Centers for Disease Control and Prevention.) Yet the relationship between forest loss and bacterial boom times isn’t a straight line, the researchers found.  As people change the landscape even more drastically toward urbanization, the niches for the bacteria-carriers appears to start shrinking again. This may mean that some of the bacteria’s favorite hosts are dwindling away, too. Other work has examined the way that landscape change affects people’s risks of catching infectious diseases, says Kate Jones of University College London, who has studied Lassa fever in Africa. Yet she cautions that recent research suggests that the interplay of infectious disease and disturbance depends strongly on the location. Some evidence has linked degraded ecosystems to rising numbers of small rodents that spread, for instance, Lyme disease. But in cases with diseases spread by monkeys and apes, their habitat needs mean they tend to be among the first animals to disappear as people take over land, taking particular disease risks with them. Just how the rise in bacteria for Buruli ulcer translates into numbers of human cases will take more study. The new study focused on the animals and landscape and did not look at human prevalence of the disease. Worldwide, some 5,000 to 6,000 new cases of Buruli ulcer are reported each year from a total of 15 countries, says the CDC. The disease is also found in at least 18 more countries not included in the statistics. Buruli ulcer can occur in temperate as well as tropical regions but is especially a risk for children and young teens in sub-Saharan Africa.


VANCOUVER, British Columbia--(BUSINESS WIRE)--lululemon athletica inc. (NASDAQ:LULU) today announced financial results for the third quarter ended October 30, 2016. For the third quarter ended October 30, 2016: The Company ended the third quarter of fiscal 2016 with $480.4 million in cash and cash equivalents compared to $403.4 million at the end of the third quarter of fiscal 2015. Inventories at the end of the third quarter of fiscal 2016 increased by 2% to $364.5 million compared to $357.8 million at the end of the third quarter of fiscal 2015. The Company ended the quarter with 389 stores. The Company also announced that its board of directors has approved a stock repurchase program for up to $100 million of its common shares in the open market at prevailing market prices. The timing and actual number of common shares to be repurchased will depend upon market conditions and other factors, in accordance with Securities and Exchange Commission requirements. The stock repurchase program is intended to create shareholder value by making opportunistic repurchases during periods of favorable market conditions. Shares may be repurchased from time to time on the open market, through block trades or otherwise. Purchases may be started or stopped at any time without prior notice depending on market conditions and other factors. Laurent Potdevin, lululemon's CEO, stated: "Our third quarter results demonstrated strong execution across all areas of our business as we delivered continued topline momentum, outperformed in gross margin and inflected meaningfully in EPS. This success is a result of our team's ongoing effort and commitment to delivering on our long term strategies." Mr. Potdevin continued: "As we entered the fourth quarter, we experienced mixed sales results that have since improved. I am inspired by the team's response and passion towards making this another successful holiday season, and I am confident that we will continue to deliver an unparalleled guest experience across all our channels and regions around the globe." For the fourth quarter of fiscal 2016, we expect net revenue to be in the range of $765 million to $785 million based on total comparable sales in the mid-single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $0.96 to $1.01 for the quarter. This guidance assumes 137.3 million diluted weighted-average shares outstanding and a 31.2% tax rate. For the full fiscal 2016, we now expect net revenue to be in the range of $2.320 billion to $2.340 billion based on total comparable sales in the mid-single digits on a constant dollar basis. Diluted earnings per share are expected to be in the range of $2.18 to $2.23 for the full year, or $2.11 to $2.16 normalized for the tax and related interest adjustments made during the first three quarters of fiscal 2016. This guidance assumes 137.3 million diluted weighted-average shares outstanding and a 28.2% tax rate, or 30.9% excluding the above tax and related interest adjustments. A conference call to discuss third quarter results is scheduled for today, December 7, 2016, at 4:30 p.m. Eastern time. Those interested in participating in the call are invited to dial 1-800-319-4610 or 1-604-638-5340, if calling internationally, approximately 10 minutes prior to the start of the call. A live webcast of the conference call will be available online at: http://investor.lululemon.com/events.cfm. A replay will be made available online approximately two hours following the live call for a period of 30 days. lululemon athletica inc. (NASDAQ:LULU) is a healthy lifestyle inspired athletic apparel company for yoga, running, training, and most other sweaty pursuits, with products that create transformational experiences for people to live happy, healthy, fun lives. Setting the bar in technical fabrics and functional designs, lululemon works with yogis and athletes in local communities for continuous research and product feedback. For more information, visit www.lululemon.com. Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue, and the effective tax rate and diluted earnings per share excluding certain tax and related interest adjustments, are not United States generally accepted accounting principle ("GAAP") financial measures. A constant dollar basis assumes the average foreign exchange rates for the current period remained constant with the average foreign exchange rates for the same period of the prior year. We provide constant dollar changes in net revenue, total comparable sales, comparable store sales, and changes in direct to consumer net revenue because we use these measures to understand the underlying growth rate of net revenue excluding the impact of changes in foreign exchange rates. We believe that disclosing these measures on a constant dollar basis is useful to investors because it enables them to better understand the level of growth of our business. We disclose the effective tax rate and diluted earnings per share excluding certain tax and related interest adjustments because of their comparability to our historical information, which we believe is useful to investors. The presentation of this financial information is not intended to be considered in isolation or as a substitute for, or with greater prominence to, the financial information prepared and presented in accordance with GAAP. For more information on these non-GAAP financial measures, please see the section captioned "Reconciliation of Non-GAAP Financial Measures" included in the accompanying financial tables, which includes more detail on the GAAP financial measure that is most directly comparable to each non-GAAP financial measure, and the related reconciliations between these financial measures. This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 that involve risks, uncertainties and assumptions, such as statements regarding our future financial condition or results of operations and our prospects and strategies for future growth. In many cases, you can identify forward-looking statements by terms such as "may," "will," "should," "expects," "plans," "anticipates," "outlook," "believes," "intends," "estimates," "predicts," "potential" or the negative of these terms or other comparable terminology. These forward-looking statements are based on management's current expectations but they involve a number of risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in the forward-looking statements as a result of risks and uncertainties, which include, without limitation: our ability to maintain the value and reputation of our brand, including any negative publicity regarding our products or the production methods of our suppliers or manufacturers; the acceptability of our products to our guests, including receiving products that comply with our technical specifications and quality standards; our highly competitive market and increasing competition; our reliance on and limited control over third-party suppliers to provide fabrics for and to produce our products; an economic downturn or economic uncertainty in our key markets; increasing product costs and decreasing selling prices; our ability to anticipate consumer preferences and successfully develop and introduce new, innovative and updated products; our ability to accurately forecast customer demand for our products; our ability to safeguard against security breaches with respect to our information technology systems; any material disruption of our information systems; our ability to manage our growth and the increased complexity of our business effectively; the fluctuating costs of raw materials; our ability to expand internationally in light of our limited operating experience and limited brand recognition in new international markets; our ability to deliver our products to the market and to meet customer expectations if we have problems with our distribution system; imitation by our competitors; our ability to protect our intellectual property rights; changes in tax laws or unanticipated tax liabilities, capital or financing needs in the United States, or our intentions with respect to the reinvestment of foreign earnings; our ability to cancel store leases if an existing or new store is not profitable; increasing labor costs and other factors associated with the production of our products in South and South East Asia; our ability to successfully open new store locations in a timely manner; our ability to comply with trade and other regulations; the continued service of our senior management; seasonality; fluctuations in foreign currency exchange rates; the operations of many of our suppliers are subject to international and other risks; our ability to source our merchandise profitably or at all; our exposure to various types of litigation; actions of activist stockholders; and other risks and uncertainties set out in filings made from time to time with the United States Securities and Exchange Commission and available at www.sec.gov, including, without limitation, our most recent reports on Form 10-K and Form 10-Q. You are urged to consider these factors carefully in evaluating the forward-looking statements contained herein and are cautioned not to place undue reliance on such forward-looking statements, which are qualified in their entirety by these cautionary statements. The forward-looking statements made herein speak only as of the date of this press release and we undertake no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances, except as may be required by law. Constant dollar changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue The below changes in net revenue, total comparable sales, comparable store sales, and direct to consumer net revenue show the net change for the third quarter of fiscal 2016 compared to the third quarter of fiscal 2015. Effective tax rate and diluted earnings per share, excluding tax and related interest adjustments Expected annual effective tax rate and diluted earnings per share, excluding tax and related interest adjustments


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Provided herein are drinks (e.g., carbonated drinks) comprising one or more unsaturated fatty acids (e.g., an omega-3, omega-6, and/or omega-9) fatty acids, wherein the drinks are characterized by a low glycemic index and/or an enhanced non-refrigerated shelf life.


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Change Inc. | Date: 2016-06-14

A computer-implemented method for enabling an individual to round up the monetary cost of a purchase to a specified amount and contribute the difference to a third party. More specifically, the method allows a user to round up a purchase to the nearest dollar or other amount and then contribute that change to a pool of donations, and further allows fundraising campaigns to compete for the pool of donations through various competitive, social media-based games. In some embodiments, the present invention may be incorporated directly within a digital wallet on a mobile device. In other embodiments the present invention may be a stand-alone application on a mobile device that interfaces with a digital wallet.

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