Moncada, Spain

CEU Cardinal Herrera University is a private university in Valencia, Spain. It is part of the CEU Foundation, being the first private school of Law ever founded in Valencia. It has been associated to the University of Valencia and Polytechnic University of Valencia since the early 1970s but the University gained its current name in 1999.The University has five faculties: Faculty of Health science, Faculty Of Veterinary, Faculty of Law, Business and Political Science, Faculty of Humanities and Communication science and ESET Technical School of Engineering. CEU-UCH offers degrees in English , in French Médecine Vétérinaire and in Spanish. It boasts three modern campuses in Moncada , Elche and Castellón. CEU-UCH currently provides high quality teaching to over 7,000 students from all over Spain, especially the regions of Valencia, Murcia, Majorca, Ibiza, and Albacete. Every year, it also welcomes a rapidly growing number of international students with programs like European's Erasmus Programme, Socrates and Leonardo. International rankings place CEU-UCH at the top of the 23 Spanish private universities, rankings like Shanghai Jiao Tong University’s Academic Ranking of World Universities placed CEU-UCH the second Spanish private university, after the University of Navarra, in terms of research in 2013. In 2014 U-Multirank, a new global university ranking financed by the EU which assesses the performance of more than 850 higher education institutions worldwide, placed CEU-UCH as the tenth European university in agreement to regional involvement, scientific productivity and international orientation Wikipedia.


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Pich A.,University of Valencia | Rosell I.,University of Valencia | Rosell I.,CEU Cardenal Herrera University | Sanz-Cillero J.J.,National Institute of Nuclear Physics, Italy | Sanz-Cillero J.J.,Peking University
Physical Review Letters | Year: 2013

We present a one-loop calculation of the oblique S and T parameters within strongly coupled models of electroweak symmetry breaking with a light Higgs-like boson. We use a general effective Lagrangian, implementing the chiral symmetry breaking SU(2)L⊠- SU(2)R→SU(2) L+R with Goldstone bosons, gauge bosons, the Higgs-like scalar, and one multiplet of vector and axial-vector massive resonance states. Using a dispersive representation and imposing a proper ultraviolet behavior, we obtain S and T at the next-to-leading order in terms of a few resonance parameters. The experimentally allowed range forces the vector and axial-vector states to be heavy, with masses above the TeV scale, and suggests that the Higgs-like scalar should have a WW coupling close to the standard model one. Our conclusions are generic and apply to more specific scenarios such as the minimal SO(5)/SO(4) composite Higgs model. © 2013 American Physical Society.


Perez-Gracia M.T.,CEU Cardenal Herrera University | Mateos Lindemann M.L.,Hospital Universitario Ramon y Cajal | Montalvo Villalba M.C.,Laboratory Hepatitis Virales
Reviews in Medical Virology | Year: 2013

SUMMARY: Acute hepatitis E is a very common disease in developing countries, to the point that, according to World Health Organization estimates, one third of the world's population has been exposed to HEV. It also causes outbreaks in refugee camps or after natural disasters such as floods or earthquakes. Sporadic cases of acute hepatitis have been observed in practically all European countries and other developed geographical areas, not only in travelers from endemic countries but also in people with no risk factors. But, lately, new aspects of this infection are appearing in industrialized countries such as the possibility of the disease becoming chronic in transplant patients, the immunocompromised in general, and even in patients with previous liver disease who are immunocompetent. In this comprehensive review, we summarize the current knowledge on HEV infection. © 2013 John Wiley & Sons, Ltd.


Albelda T.M.,University of Valencia | Garcia-Espana E.,University of Valencia | Frias J.C.,GIBI230 | Frias J.C.,CEU Cardenal Herrera University
Chemical Society Reviews | Year: 2014

Atherosclerosis is the major underlying pathologic cause of coronary artery disease. An early detection of the disease can prevent clinical sequellae such as angina, myocardial infarction, and stroke. The different imaging techniques employed to visualize the atherosclerotic plaque provide information of diagnostic and prognostic value. Furthermore, the use of contrast agents helps to improve signal-to-noise ratio providing better images. For nuclear imaging techniques and optical imaging these agents are absolutely necessary. We report on the different contrast agents that have been used, are used or may be used in future in animals, humans, or excised tissues for the distinct imaging modalities for atherosclerotic plaque imaging. This journal is © the Partner Organisations 2014.


Perez-Gracia M.T.,CEU Cardenal Herrera University | Suay B.,CEU Cardenal Herrera University | Mateos-Lindemann M.L.,Hospital Universitario Ramon y Cajal
Infection, Genetics and Evolution | Year: 2014

Currently, the infection with the hepatitis E virus represents the most frequent cause for acute hepatitis and jaundice in the world. According to WHO estimations, around two billion people, representing one third of the world's population, live in endemic areas for HEV and, therefore, are at risk of infection. In developed countries, the circulation of the virus in both human and animal (swine, boar, deer) sewage has been confirmed; however, the incidence rate is low compared to that of developing countries where outbreaks of acute hepatitis transmitted via the fecal-oral route are originated, more frequently in the flooding season or after natural disasters, combined with deficient sanitary conditions.There are currently 4 known genotypes of HEV. Genotypes 1 and 2 are isolated in all human epidemic outbreaks in developing countries, while genotypes 3 and 4 are isolated not only in humans but also in animals, in both developing and industrialized countries. These data support genotypes 3 and 4 having zoonotic nature. The diagnosis of this disease is based in the detection of anti-HEV IgG and IgM in blood serum using enzyme-linked immunosorbent methods. However, the method that best confirms the diagnosis is the RT-PCR, which detects HEV RNA in blood serum and also provides the genotype. The clinical course is generally that of an acute hepatitis which in some cases may require hospitalization and that, in transplant patients or HIV infected individuals can become a chronic hepatitis. Furthermore, the virus constitutes an important risk for pregnant women. The hepatitis E can present a wide range of symptoms, from a subclinical case to chronic liver disease with extrahepatic manifestations. For this reason, the diagnostic is challenging if no differential diagnosis is included. There is no specific antiviral drug for hepatitis E, but satisfactory results have been observed in some patients treated with pegylated interferon alfa2a and/or ribavirin.This revision is an update of all the molecular, epidemiological, clinic and preventive knowledge on this emergent disease up to date. © 2014 Elsevier B.V.


Teresa Albelda M.,University of Valencia | Frias J.C.,University of Valencia | Frias J.C.,CEU Cardenal Herrera University | Garcia-Espana E.,University of Valencia | Schneider H.-J.,Saarland University
Chemical Society Reviews | Year: 2012

Supramolecular complexes offer a new and efficient way for the monitoring and removal of many substances emanating from technical processes, fertilization, plant and animal protection, or e.g. chemotherapy. Such pollutants range from toxic or radioactive metal ions and anions to chemical side products, herbicides, pesticides to drugs including steroids, and include degradation products from natural sources. The applications involve usually fast and reversible complex formation, due to prevailing non-covalent interactions. This is of importance for sensing as well as for separation techniques, where the often expensive host compounds can then be reused almost indefinitely. Immobilization of host compounds, e.g. on exchange resins or on membranes, and their implementation in smart new materials hold particular promise. The review illustrates how the design of suitable host compounds in combination with modern sensing and separation methods can contribute to solve some of the biggest problems facing chemistry, which arise from the everyday increasing pollution of the environment. © 2012 The Royal Society of Chemistry.


Falco A.,CEU Cardenal Herrera University | Hackbusch W.,Max Planck Institute Mathematik in den Naturwissenschaften
Foundations of Computational Mathematics | Year: 2012

In this paper we introduce and develop the notion of minimal subspaces in the framework of algebraic and topological tensor product spaces. This mathematical structure arises in a natural way in the study of tensor representations. We use minimal subspaces to prove the existence of a best approximation, for any element in a Banach tensor space, by means of a tensor given in a typical representation format (Tucker, hierarchical, or tensor train). We show that this result holds in a tensor Banach space with a norm stronger than the injective norm and in an intersection of finitely many Banach tensor spaces satisfying some additional conditions. Examples using topological tensor products of standard Sobolev spaces are given. © 2012 SFoCM.


Penades J.R.,University of Glasgow | Chen J.,New York University | Quiles-Puchalt N.,University of Glasgow | Quiles-Puchalt N.,CEU Cardenal Herrera University | And 3 more authors.
Current Opinion in Microbiology | Year: 2015

Bacteriophages are types of viruses that infect bacteria. They are the most abundant and diverse entities in the biosphere, and influence the evolution of most bacterial species by promoting gene transfer, sometimes in unexpected ways. Although pac-type phages can randomly package and transfer bacterial DNA by a process called generalized transduction, some mobile genetic elements have developed elegant and sophisticated strategies to hijack the phage DNA-packaging machinery for their own transfer. Moreover, phage-like particles (gene transfer agents) have also evolved, that can package random pieces of the producing cell's genome. The purpose of this review is to give an overview of some of the various ways by which phages and phage-like particles can transfer bacterial genes, driving bacterial evolution and promoting the emergence of novel pathogens. © 2014 Elsevier Ltd.


Arguisuelas M.D.,CEU Cardenal Herrera University
Spine | Year: 2016

STUDY DESIGN.: Double-blind, randomized parallel sham-controlled trial with concealed allocation and intention-to treat analysis. OBJECTIVE.: To investigate the effects of an isolate Myofascial Release protocol (MFR) on pain, disability and fear- avoidance beliefs in patients with chronic low back pain (CLBP). SUMMARY OF BACKGROUND DATA.: MFR is a form of manual medicine widely used by physiotherapists in the management of different musculoskeletal pathologies. Up to this moment, no previous studies have reported the effects of an isolated MFR treatment in patients with CLBP. METHODS.: Fifty four participants, with nonspecific CLBP, were randomized to MFR group (n?=?27) receiving four sessions of myofascial treatment, each lasting 40 minutes, and to control group (n?=?27) receiving a sham MFR. Variables studied were pain measured by means Short Form McGill Pain questionnaire (SF-MPQ) and visual analogue scale (VAS), disability measured with Roland Morris questionnaire and Fear-Avoidance Beliefs measured with FAB questionnaire (FABQ). RESULTS.: Subjects receiving MFR displayed significant improvements in pain (SF-MPQ) (mean difference -7.8; 95% CI: -14.5 to -1.1, P?=?0.023) and sensory SF-MPQ subscale (mean difference -6.1; 95% CI: -10.8 to -1.5, P?=?0.011) compared to the sham group, but no differences were found in VAS between groups. Disability and the FABQ score also displayed a significant decrease in the MFR group (P?


Espana-Boquera S.,Polytechnic University of Valencia | Castro-Bleda M.J.,Polytechnic University of Valencia | Gorbe-Moya J.,Polytechnic University of Valencia | Zamora-Martinez F.,Polytechnic University of Valencia | Zamora-Martinez F.,CEU Cardenal Herrera University
IEEE Transactions on Pattern Analysis and Machine Intelligence | Year: 2011

This paper proposes the use of hybrid Hidden Markov Model (HMM)/Artificial Neural Network (ANN) models for recognizing unconstrained offline handwritten texts. The structural part of the optical models has been modeled with Markov chains, and a Multilayer Perceptron is used to estimate the emission probabilities. This paper also presents new techniques to remove slope and slant from handwritten text and to normalize the size of text images with supervised learning methods. Slope correction and size normalization are achieved by classifying local extrema of text contours with Multilayer Perceptrons. Slant is also removed in a nonuniform way by using Artificial Neural Networks. Experiments have been conducted on offline handwritten text lines from the IAM database, and the recognition rates achieved, in comparison to the ones reported in the literature, are among the best for the same task. © 2006 IEEE.


Exercise as a therapeutic tool used in End-stage renal disease patients (ESRD) in hemodialysis (HD) is not routinately applied, as it occurs with cardiac or respiratory patients. Lack of awareness of research in this field may contribute to the current situation. Thus, the aims of this review are: 1) to systematically review the literature of exercise training on adult HD patients or patients at a pre-HD stage; 2) to show the evidence on the benefits of exercise for counteracting physiological, functional and psychological impairments found even in older ESRD patients; 3) to recommend requirements of future research in order to include exercise prescription in the HD patients treatment. The Data bases reviewed from 2005 to 2009 were: MEDLINE (Ovid), CINAHL (EBSCOHost), SportDicus (EBSCOHost), Academic Search Complete (EBSCOHost), Fuente Académica (EBSCOHost), MedicLatina (EBSCOHost), PEDro y PubMed. Additionally, references from identified articles, several reviews on ESRD and abstracts to Nephrology Congresses were also reviewed. Randomized Controlled Trials on aerobic, strength and combined programs for HD patients were selected. Data from the studies was compiled and Van Tulder criteria were used for methodological quality assessment. Metanalysis included 6 studies on aerobic exercise, 2 on strength exercise and 5 on combined exercise programs. 640 patients were included in 16 included studies. Effects on physical function, health related quality of life and other secondary measurements were summarized by the Standardized Mean Difference (SMD) Moderate evidence exists on positive effects of aerobic training on peak oxygen consumption at the graded exercise test (SMD 6.55; CI 95%: 4.31-8.78). There is high evidence on positive effects of strength training on health related quality of life (SMD 11.03; CI 95%: 5.63-16.43). Finally, moderate evidence exists on positive effects of combined exercise on peak oxygen consumption at the graded exercise test (SMD 5.57; CI 95%: 2.52-8.61). Summarizing, moderate evidence exists on the improvement on exercise capacity of aerobic training, isolated or combined with strength training. Strength training improves health related quality of life, functional capacity and lower limbs strength. Future studies should clarify which out of the three modalities results in higher benefits for HD patients.

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