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Le Touquet – Paris-Plage, France

Patent
Cephalon France | Date: 2011-05-11

The present invention relates to a method for regioselectively reducing the maleimide compounds of formula (I). The invention also relates to C


Patent
Cephalon France | Date: 2012-06-04

The present invention relates to novel oral pharmaceutical compositions in lyophilized form, in which the dissolution and the bioavailability of the active ingredient that they contain are improved. The compositions according to the invention comprise in particular a polyvinyl acetate/polyvinylpyrrolidone copolymer. The oral lyophilisates according to the invention are particularly suitable for the production of medicaments based on active ingredients which have low solubility or very low solubility in water or which are virtually insoluble in water.


Patent
Cephalon France | Date: 2012-06-04

The present invention relates to a method for preparing an oral lyophilizate composition comprising:


Patent
Cephalon France and Cephalon Inc. | Date: 2011-09-29

Lyophilized cakes of proteasome inhibitors are described, as well as methods for their production and use.


The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of: wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1.

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