Cephalon France

Paris, France

Cephalon France

Paris, France
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The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:


Patent
Cephalon France | Date: 2012-06-04

The present invention relates to novel oral pharmaceutical compositions in lyophilized form, in which the dissolution and the bioavailability of the active ingredient that they contain are improved. The compositions according to the invention comprise in particular a polyvinyl acetate/polyvinylpyrrolidone copolymer. The oral lyophilisates according to the invention are particularly suitable for the production of medicaments based on active ingredients which have low solubility or very low solubility in water or which are virtually insoluble in water.


The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:


Patent
Cephalon France and Cephalon Inc. | Date: 2012-11-16

The present invention relates a method for purifying a fused pyrrolocarbazole compound known as 11-isobutyl-2-methyl-8-(2-pyrimidinylamino)-2,5,6,11,12,13-hexahydro-4Hindazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one using an acid complex thereof. The present invention also relates to a crystalline form of the acid complex.


Patent
Cephalon France | Date: 2011-04-26

The invention concerns an oral lyophilizate comprising modafinil particles having a median diameter of about 10 to about 1000 m in association with an appropriate amount of at least one excipient selected from the group consisting of fatty acid esters of glycerol, cyclic oligosaccharides, sweeteners or mixtures thereof.


Patent
Cephalon France | Date: 2011-05-11

The present invention relates to a method for regioselectively reducing the maleimide compounds of formula (I). The invention also relates to C_(7 )hydroxy lactam regioisomers of formula (II) obtainable by this method and their use for the preparation of lactams of formula (III) which are particularly useful as intermediate for the synthesis of fused pyrrolocarbazoles.


Patent
Cephalon France and Cephalon Inc. | Date: 2011-12-22

The present invention provides compounds of formula I: their use as H_(3 )antagonists/inverse agonists, processes for their preparation, and pharmaceutical compositions thereof.


Patent
Cephalon France | Date: 2012-01-04

The present invention relates to modafinil polymorphic form VI, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic form VI.


The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of: wherein Ar, Y, R^(1 )are as defined in claim 1.


Patent
Cephalon France | Date: 2012-06-04

The present invention relates to a method for preparing an oral lyophilizate composition comprising:

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