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Andreoli C.P.P.,Centro Universitario Herminio Ometto | De Martino M.M.F.,University of Campinas
Sleep Science | Year: 2012

Objectives: The assessment of student achievement in the teaching-learning is a constant concern of the study professors. Actually the night shift is a reality in favor of the persons seeking qualification for a position in the labor market. This study aimed to evaluate the academic performance and correlate with the indices of student achievement and sleep patterns. Methods: Participants were college students from the University Center Herminio Ometto, UNIARARAS, SP, (n = 139) with a mean age of 23.59 years. Were used: a questionnaire to gather personal information and professional evaluation of sleep-wake cycle (sleep diaries), validated by Benedito-Silva et al. (1990). For the analysis of academic performance, we used the Scheduled System Assessment (SPA). Results: The sleep patterns were statistically different between groups (Mann-Whitney) for the variables bedtime (p < 0.001), bedtime (p <0.001), time to wake up (p <0.001) and duration nap (p = 0.009). As for academic performance, students in the daytime period had higher mean values when compared with the group the night. Conclusion: The group of diurnal periods showed better academic performance in comparison with that of the night. The later the hour of waking, the lower academic performance, suggesting the effect of nighttime sleep and deficits. The sleep quality was better for the group of the day.

Blay S.L.,University of Sao Paulo | Marchesoni M.S.M.,Centro Universitario Herminio Ometto
Cadernos de Saude Publica | Year: 2011

The aim of this study is to investigate the impact of psychiatric morbidity, depression, cognitive deficit, number of self-reported illnesses and socio-demographic variables on the WHOQOLBref domain scores. WHOQOL-Bref domain scores are substantially affected by psychiatric morbidity and income. Depression, the number of selfreported illnesses and the female gender also explain the variability of other domains to a lesser extent.

Tessutti L.S.,University of Campinas | Macedo D.V.,University of Campinas | Kubota L.T.,University of Campinas | Alves A.A.,University of Campinas | Alves A.A.,Centro Universitario Herminio Ometto
Analytical Biochemistry | Year: 2013

The use of potentiometry to measure plasma antioxidant capacity to contribute to oxidative stress evaluation is presented. In this assay, plasma (n = 60) diluted (0.3 to 1 ml) in phosphate buffer, pH 7.4, NaCl 9%, was submitted to potentiometry. A platinum wire was the working electrode and saturated calomel the reference. The results are presented as the difference between sample and buffer potential (ΔE). ΔE presented a good inverse correlation with added increasing concentrations of ascorbate (2.5-75 μmol/L; R = -0.99), urate (9.0-150 μmol/L; R = -0.99), and bilirubin (0.78-13 μmol/L; R = -0.99). Increase in the antioxidant capacity decreased ΔE. Depletion of the antioxidant capacity by tert-butylhydroperoxide (6.5-50 μmol/L) presented a direct correlation (0.97) with ΔE. Furthermore, ΔE presented an inverse correlation (R = -0.99) with increased antioxidant capacity of plasma (FRAP) induced by the addition of ascorbate (2.5-75 μmol/L). The response of the potentiometric method proved be adequate for measuring the plasma antioxidant depletion induced by acute exhaustive exercise in rats (control, n = 15; exercised, n = 15). This exercise decreased the concentration of urate (p < 0.05), decreased FRAP (p < 0.5), increased TBARS (p < 0.5), and decreased the potentiometer sensor response (p = 6.5 × 10-3). These results demonstrate the adequacy of potentiometry for evaluating the antioxidant capacity of blood plasma samples. © 2013 Elsevier Inc. All rights reserved.

Clerici M.T.P.S.,Federal University of Alfenas | Kallmann C.,Centro Universitario Herminio Ometto | Gaspi F.O.G.,Centro Universitario Herminio Ometto | Morgano M.A.,Institute Tecnologia Of Alimentos Ital | And 2 more authors.
Food Research International | Year: 2011

Fruit of wolf (Solanum lycocarpum A. St. - HILL), found in Brazilian cerrado, has been used in the initial ripening stage as flour and/or starch in popular medicine due to its hypoglycemiant action. The aim of this work was to study the occurrence of phytochemical compounds, physical, chemical and technological characteristics of fruit of wolf flour and starch in the initial ripening stage. Flour and starch were extracted using known popularly and experimental methods (with sodium bisulfite) and chemical composition and technological characteristics were analyzed. The results were comparatively assessed by Tukey's test (p < 0.05). The recommendation for use was the extraction of flour and starch products by previously removing peels and seeds of fruit of wolf. The most relevant finding in this study is the high content of fibers in flour (23. g/100. g) and high content of resistant starch (32. g/100. g) in the fraction of starch extracted from fruit of wolf, which can explain their use as hypoglycemic agent. © 2011 Elsevier Ltd.

Pires R.C.,Centro Universitario Herminio Ometto | Souza E.E.,Centro Universitario Herminio Ometto | Vanzela E.C.,University of Campinas | Ribeiro R.A.,Federal University of Rio de Janeiro | And 4 more authors.
Applied Physiology, Nutrition and Metabolism | Year: 2014

The occurrence of metabolic disorders, such as diabetes, obesity, atherosclerosis, and hypertension, increases with age. Inappropriate food intake, when combined with genetic and hormonal factors, can trigger the occurrence of these diseases in aged organisms. This study investigated whether short-term calorie restriction (CR; 40% of the intake of control animals (CTL) for 21 days) benefits 1-year-old (CR1yr) and 2-year-old (CR2yr) Wistar rats, with regard to insulin secretion and action. Plasma insulin and the insulin secreted by isolated islets were measured with radioimmunoassay, and the insulin sensitivity of peripheral tissues was assessed with the intraperitoneal glucose tolerance test (IPGTT), intraperitoneal insulin tolerance test, and hepatic and muscle adenosine monophosphate-activated protein kinase (AMPK) phosphorylation measurements. Body weight, epididymal fat pad, epididymal fat pad/body weight index, plasma glucose, and insulin were lower in the CR1yr than in the control (CTL1yr) rats. Serum cholesterol, triglycerides, and protein, as well as hepatic and muscle glycogen content, were similar between the CR and CTL groups. The IPGTT was higher in CR2yr and CTL2yr rats than in CR1yr and CTL1yr rats, and insulin sensitivity was higher in CR1yr and CR2yr rats than in their respective CTLs. This was associated with an increase in hepatic and muscle AMPK phosphorylation. No differences in glucose-induced insulin secretion in the isolated islets were observed between CRs and their respective CTL rats. In conclusion, short-term calorie restriction provoked more severe alterations in CR1yr than CR2yr rats. The normoglycemia observed in both CR groups seems to be due to an increase in insulin sensitivity, with the involvement of liver and muscle AMPK.

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