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Viveiros F.Z.,General Motors | Colosio M.A.,General Motors | Rossini E.L.,Centro Universitario Fundacao Santo Andre
SAE Technical Papers | Year: 2013

This work conducted an optimization in sheet metal blank's sizes for cold pressing automotive parts, comparing dimensional characteristics of automotive hood outer panels deep drawn with commonly used blank sizes for this process. As a result, it was possible to suggest modifications to smaller blank sizes, accordingly to the improvement accomplished in this work. The experimental study was conducted from observations in part's superficial aspects after its deep drawing process, which was realized in a commonly used tooling for automotive industry, with a blank's width reduction for the suggested case. The results showed a cost reduction opportunity based in this optimization. © 2013 SAE INTERNATIONAL. Source


De Campos F.,Sao Paulo State University | Iboli O.J.P.,University of Sao Paulo | Hirsch M.,University of Valencia | Magro M.B.,University of Sao Paulo | And 5 more authors.
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2010

The lightest supersymmetric particle may decay with branching ratios that correlate with neutrino oscillation parameters. In this case the CERN Large Hadron Collider (LHC) has the potential to probe the atmospheric neutrino mixing angle with sensitivity competitive to its low-energy determination by underground experiments. Under realistic detection assumptions, we identify the necessary conditions for the experiments at CERN's LHC to probe the simplest scenario for neutrino masses induced by minimal supergravity with bilinear R parity violation. © 2010 The American Physical Society. Source


Magro M.B.,Centro Universitario Fundacao Santo Andre
Journal of Physics: Conference Series | Year: 2010

We present a brief review on the features of bilinear R-parity violation in mSUGRA models at the LHC. These kind of models can provied a way of probing neutrino oscillation physics at colliders. We show that the LHC will be able to cover such models for a large fraction of the parameter space. © 2010 IOP Publishing Ltd. Source


De Campos F.,Sao Paulo State University | De Campos F.,University of Valencia | Iboli O.J.P.,University of Sao Paulo | Magro M.B.,CEA Saclay Nuclear Research Center | And 5 more authors.
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2012

Supersymmetric models with bilinear R-parity violation can account for the observed neutrino masses and mixing parameters indicated by neutrino oscillation data. We consider minimal supergravity versions of bilinear R-parity violation where the lightest supersymmetric particle is a neutralino. This is unstable, with a large enough decay length to be detected at the CERN Large Hadron Collider. We analyze the Large Hadron Collider potential to determine the lightest supersymmetric particle properties, such as mass, lifetime and branching ratios, and discuss their relation to neutrino properties. © 2012 American Physical Society. Source


Linhares J.J.,Federal University of Ceara | Linhares J.J.,Federal University of Sao Paulo | Azevedo Jr M.,Federal University of Sao Paulo | Siufi A.A.,Federal University of Sao Paulo | And 7 more authors.
BMC Medical Genetics | Year: 2012

Background: Emerging evidence has shown that miRNAs are involved in human carcinogenesis as tumor suppressors or oncogenes. Single nucleotide polymorphisms (SNPs) located in pre-miRNAs may affect the processing and therefore, influence the expression of mature miRNAs. Previous studies generated conflicting results when reporting association between the hsa-miR-196a2 rs11614913 common polymorphism and breast cancer.Methods: This study evaluated the hsa-miR-196a2 rs11614913 SNP in 388 breast cancer cases and 388 controls in Brazilian women. Polymorphism was determined by real-time PCR; control and experimental groups were compared through statistical analysis using the X2 or Fisher's exact tests.Results: The analysis of the SNPs frequencies showed a significant difference between the groups (BC and CT) in regards to genotype distribution (χ2: p = 0.024); the homozygous variant (CC) was more frequent in the CT than in the BC group (p = 0.009). The presence of the hsa-miR-196a2 rs11614913 C/T polymorphism was not associated with histological grades (p = 0.522), axillary lymph node positive status (p = 0.805), or clinical stage (p = 0.670) among the breast cancer patients.Conclusions: The results of this study indicated that the CC polymorphic genotype is associated with a decreased risk of BC and the presence of the T allele was significantly associated with an increased risk of BC. © 2012 Linhares et al.; licensee BioMed Central Ltd. Source

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