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San Fedele Superiore, Italy

The aim of this study was to estimate the prevalence of HPV infection in women in the general population and identify associated risk factors. Five hundred women participating in a cervical cancer screening program were included in the study which was performed in Asti between April 2005 and October 2005. The prevalence of HPV infection was 10.6%. The most common genotypes were types 18, 16, 51 and 31. Cigarette smoke and oral contraceptive use were found to be significantly associated with infection. Source


Luzi A.M.,Centro Operativo AIDS | De Mei B.,Centro Of Epidemiologia | Colucci A.,Centro Operativo AIDS | Gallo P.,Centro Operativo AIDS
Annali dell'Istituto Superiore di Sanita | Year: 2010

In the present work, we outline basic health counselling skills, specifically, those for performing pre-test and post-test counselling for HIV infection. The ultimate goal is to propose that counselling be performed in facilities that carry out screening for anti-HIV antibodies, following standardised (and thus replicable) criteria, with consistent focus on the quality of the relationship between the healthcare professional and the individual undergoing testing and on the individual's specific needs. Source


Fanales-Belasio E.,Centro Nazionale AIDS | Raimondo M.,Centro Operativo AIDS | SuligoI. B.,Centro Operativo AIDS | Butto S.,Centro Nazionale AIDS
Annali dell'Istituto Superiore di Sanita | Year: 2010

Studies on HIV virology and pathogenesis address the complex mechanisms that result in the HIV infection of the cell and destruction of the immune system. These studies are focused on both the structure and the replication characteristics of HIV and on the interaction of the virus with the host. Continuous updating of knowledge on structure, variability and replication of HIV, as well as the characteristics of the host immune response, are essential to refine virological and immunological mechanisms associated with the viral infection and allow us to identify key molecules in the virus life cycle that can be important for the design of new diagnostic assays and specific antiviral drugs and vaccines. In this article we review the characteristics of molecular structure, replication and pathogenesis of HIV, with a particular focus on those aspects that are important for the design of diagnostic assays. Source


Zucchetto A.,Centro Of Riferimento Oncologico | Suligoi B.,Centro Operativo AIDS | De Paoli A.,Centro Of Riferimento Oncologico | Pennazza S.,National Institute of Statistics | And 7 more authors.
Clinical Infectious Diseases | Year: 2010

During the period 1999-2006, non-AIDS-defining cancers accounted for 7.4% of deaths among Italian people with AIDS. The risk of death was 6.6-fold higher than in the general population, being particularly elevated for virus-related cancers. The study findings highlighted the importance of monitoring the cancer burden on mortality for people with AIDS. © 2010 by the Infectious Diseases Society of America. All rights reserved. Source


Overview of the impact of ano-genital warts in Italy. In Italy, the HPV infection is not subject to mandatory reporting, the available epidemiological data come from sentinel surveillance of STIs and show a high spread among young people under 25 years and an increase in reports after 2004. Although ano-genital warts are a benign disease, nonetheless they are characterized by a big relational and psycho-sexual impact, due also to high recurrence rates. It is extremely useful to promote information activities, education in safe sex, early diagnosis and treatment of genital warts. In this context, primary prevention through vaccination represents a valid tool of protection. Source

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