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Annunziata M.A.,Irccs Centro Of Riferimento Oncologico Of Aviano | Muzzatti B.,Irccs Centro Of Riferimento Oncologico Of Aviano
Recenti Progressi in Medicina

The presence of depressive symptoms and states compromises the quality of life of the oncological patients and the therapeutic adherence. It can also negatively influence prognosis and survival. In this contribution, relevance, issues and modality of registration of this construct in oncological patients will be discussed. Source

Bidoli E.,Irccs Centro Of Riferimento Oncologico Of Aviano | Barbone F.,University of Udine | Barbone F.,University of Trieste | Collarile P.,Agenzia Regionale Protezione Ambientale | And 6 more authors.
International Journal of Environmental Research and Public Health

We assessed the risk of lung cancer in people living near the iron foundry located within the city of Trieste, Northeastern Italy. Between 1995 and 2009, all incident cases of lung cancer and corresponding population were considered. A deposition model of the foundry-specific emissions of SO2 defined: “nearby”, “urban”, and “outlying” areas. Rate ratios (RRs) and annual percent changes (APCs) were computed. Among nearby residents, significantly increased risks of lung cancer were noted in men below age 75 years (RR = 1.35 vs. urban area; 95% CI: 1.03–1.77). In women, and in men aged 75 years or older, no significant RRs were observed. Conversely, people living in the outlying area appeared to be at lower risk than residents in the urban area- in all age groups, in men (RR = 0.87; 95% CI: 0.78–0.98) and in women (RR = 0.74; 95% CI: 0.62–0.88). Negative statistically significant APC was recorded in men living in urban areas (–2.6%), whereas in women APC significantly increased among those living in the urban area (+2.3%). Multiple interpretations for this observation are plausible, since several factors might have modified and/or confounded the risk of lung cancer, including air pollution from other sources and road traffic, occupational and smoking patterns. © 2015 by the authors; licensee MDPI, Basel, Switzerland. Source

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