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Donostia / San Sebastian, Spain

CEIT is a non-profit research institute created by the University of Navarra in 1982 and located in Donostia-San Sebastian, Gipuzkoa, in northern Spain. CEIT carries out applied industrial research projects through collaboration with industrial R&D departments on a contractual basis. In 2010 CEIT had a workforce of around 300 and an annual budget of over €32 million. Hitherto 12 spin-offs have been created in which there are over 300 people employed.CEIT belongs to the IK4 Research Alliance with 9 members from the Basque Country: CEIT, Cidetec, Gaiker, Ideko, Ikerlan, Tekniker, Vicomtech, Azterlan and Lortek. It has also ties with Tecnun School of Engineering, the Fraunhofer Society in Germany, the European Bioengineering Alliance, the European Rail Research Network of Excellence EURNEX and other R&D institutions and research centres on the world.The work of CEIT is divided across several core research areas: Materials Engineering, Applied Mechanics, Electronics & Communications, Environmental Engineering, Microelectronics & Microsystems and Biomedical Engineering. Some notable researchers include Javier Gil Sevillano, Pedro Crespo, Jordi Viñolas and current Director Alejo Avello. Recent noteworthy projects have included biorobotics and surgical simulation, technological applications for the support of independent living for the elderly , advanced water treatment technologies, and Integrated Circuits Design for RFID Applications.There are plans to open a new bio-engineering centre jointly with the University of Navarra in 2011 Wikipedia.

Rodriguez-Couto S.,Centro de estudios e investigaciones tecnicas de Gipuzkoa | Rodriguez-Couto S.,Ikerbasque
Journal of Hazardous Materials | Year: 2012

Cubes of nylon sponge, cubes of polyurethane foam (PUF), cuttings of stainless steel sponges and the commercial carriers Kaldnes™ K1 were tested as inert supports for laccase production by the white-rot fungus Trametes pubescens under semi-solid-state fermentation conditions. The cultures operating with Kaldnes™ K1 led to the highest laccase activity (3667. U/l). In addition this support could be re-utilised, making the whole process more economical. Subsequently, the decolouration of simulated textile wastewater (STW) by T. pubescens grown on the different tested supports under semi-solid-state fermentation conditions was studied. Decolouration percentages around 66-80% were obtained in 96. h. It was found that STW decolouration was due to two mechanisms: laccase action (biodegradation) and adsorption onto fungal mycelium, save for the PUF cultures in which decolouration was mainly due to adsorption onto the support. Further, the decolouration of STW by Kaldnes™ K1 cultures in three successive batches of 96. h each was studied. Decolouration percentages of 51.3, 70.0 and 69.8%, were attained for each batch, respectively. © 2012 Elsevier B.V.

Osma J.F.,Rovira i Virgili University | Toca-Herrera J.L.,Biosurfaces | Rodriguez-Couto S.,Centro de estudios e investigaciones tecnicas de Gipuzkoa | Rodriguez-Couto S.,Ikerbasque
Applied Catalysis A: General | Year: 2010

Laccase from Trametes pubescens was immobilised on alumina pellets and coated with polyelectrolytes. It was shown that this approach enhanced both laccase stability and reusability. Further, the immobilised-coated laccase was applied to the decolouration of a simulated textile effluent in laboratory-scale reactors. The simulated textile effluent was based on the recalcitrant diazo dye Reactive Black 5 (0.5 g/L). It was found that the decolouration was due to two processes: dye adsorption on the immobilisation support and coating and dye degradation by the laccase enzyme. The adsorption process represented less than 10% of colour removal for all cases, so decolouration was mainly due to laccase action. The decolouration was performed in both batch and continuous modes. A complete decolouration of the effluent was obtained in 30-36 h for the former and 48 h for the latter without the addition of redox mediators. In addition, the decolourised effluent showed lower phytotoxicity than the original one. These encouraging results make the process suitable for its potential implementation at industrial scale. © 2009 Elsevier B.V. All rights reserved.

Osma J.F.,Rovira i Virgili University | Toca-Herrera J.L.,Biosurfaces | Rodriguez-Couto S.,Centro de estudios e investigaciones tecnicas de Gipuzkoa | Rodriguez-Couto S.,Ikerbasque
Bioresource Technology | Year: 2010

This study deals with the biotransformation products obtained from the transformation of the anthraquinonic dye Remazol Brilliant Blue R (RBBR) by immobilised laccase from the white-rot fungus Trametes pubescens. A decolouration percentage of 44% was obtained in 42. h. RBBR transformation products were investigated using ultraviolet-visible (UV-vis) spectrum scan and High Performance Liquid Chromatography/Mass Spectrometry (LC-MS) analysis. Two compounds were identified as the transformation intermediates (m/. z 304.29 and m/. z 342.24) and other two as the final transformation products (m/. z 343.29 and m/. z 207.16). As a result a metabolic pathway for RBBR transformation by laccase was proposed. No backward polymerisation of the transformation products resulting in recurrent colouration was observed after laccase treatment of RBBR. It was also found that the biotransformation products of RBBR showed less phytotoxicity than the dye itself. © 2010 Elsevier Ltd.

Vervynckt S.,Ghent University | Verbeken K.,Ghent University | Verbeken K.,Max Planck Institute Fur Eisenforschung | Lopez B.,Centro de estudios e investigaciones tecnicas de Gipuzkoa | Jonas J.J.,McGill University
International Materials Reviews | Year: 2012

The use of heavy gauge steel sheets for structural applications often requires a combination of high yield strength and adequate toughness. The most cost effective way to achieve high yield strength and high ductility in low alloyed steels is through grain refinement. In industrial practice, such refinement is commonly obtained by thermomechanical controlled processing (TMCP). This approach comprises slab reheating to well defined temperatures, a large amount of hot deformation below the non-recrystallisation temperature T nr and accelerated cooling. In practice, the T nr is generally raised by the addition of microalloying elements such as Nb and Ti. As these elements contribute substantially to the alloying costs, optimisation of their use allows for a decrease in production cost. Better understanding of the T nr assists in tuning the rolling process so that optimum mechanical properties can be produced. One area of importance is to recognise that the concept of the T nr was originally developed for reversing mills and the production of plate steels. Methods of defining and determining it must be modified if it is to be applied to strip mills and their associated short interpass times. The main goal of this review is to provide a concise and complete overview of the current understanding of the fundamental mechanisms that control the T nr and to address the different methods that can be used to determine it. © 2012 Institute of Materials, Minerals and Mining and ASM International.

Rodriguez-Couto S.,Centro de estudios e investigaciones tecnicas de Gipuzkoa | Rodriguez-Couto S.,Ikerbasque
Journal of Hazardous Materials | Year: 2011

Laccase production by Trametes pubescens grown on sunflower-seed shells (SS) under solid-state fermentation (SFF) conditions in temporary immersion bioreactors was studied. Three immersion cycles were considered: 1min immersed and 9min non-immersed, 1min immersed and 30min non-immersed and 1min immersed and 60min non-immersed. The latter led to the highest laccase activities (4000-6000Ul-1). Also, the in vitro and in vivo decolouration of the recalcitrant textile dye Remazol Brilliant Blue R (RBBR) was assessed. It was found that RBBR (133.33mgl-1) was efficiently decolourised by T. pubencens grown on SS under SSF conditions in temporary immersion bioreactors in five successive batches. The percentage of RBBR decolouration was higher than 55% in 4h and around 70% in 24h in all the batches. However, it was found that RBBR decolouration by the crude culture filtrates was more advantageous. Thus, an RBBR decolouration percentage of nearly 80% in 2h was obtained. © 2011 Elsevier B.V.

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