Central University of Kerala is one of the 15 new Central Universities established under The Central Universities Act, 2009 . CUK aims to extend the scope of learning through a holistic methodology that accommodates diverse linguistic, scientific and cultural traditions. CUK is situated at Kasaragod, the northern-most district of Kerala, and has state-wide jurisdiction. It started functioning from a transit campus in Vidyanagar housing the Administrative Offices, Humanities Schools, University Library, Computer Centre, Language Lab, and the University Guest House. The Riverside Transit Campus at Padannakad, 35 km further south, houses the Science Schools. The permanent campus of the university is being set up at Periye on a panoramic stretch of 310 acres of land beside the National Highway, at which academic activity will commence from the ensuing academic year. Wikipedia.
Babu D.T.,Cochin University of Science and Technology |
Antony S.P.,Cochin University of Science and Technology |
Joseph S.P.,Cochin University of Science and Technology |
Bright A.R.,Central University of Kerala |
Philip R.,Cochin University of Science and Technology
Journal of Invertebrate Pathology | Year: 2013
A marine yeast Candida aquaetextoris S527 as a source of immunostimulant in Penaeus monodon was studied. Yeast diet was prepared by incorporating 10% C. aquaetextoris S527 biomass into a standard shrimp diet and administered in P. monodon at different frequencies (daily, once in three days, once in seven days and once in ten days) followed by challenge with white spot syndrome virus (WSSV). Immune parameters such as total protein, total hemocyte count, pro-phenoloxidase, nitroblue tetrazolium reduction, alkaline phosphatase activity and acid phosphatase activity were tested. Expression profile of antimicrobial peptide (AMP) genes viz., anti-lipopolysaccharide factor (ALF), crustin-1, crustin-2, crustin-3, penaeidin-3 and penaeidin-5; immune genes viz., alpha-2-macroglobulin (α-2-M), astakine, peroxinectin, prophenol oxidase (proPO) and transglutaminase, and WSSV genes viz., DNA polymerase, endonuclease, protein kinase, immediate early gene, latency related gene, ribonucleotide reductase, thymidine kinase and VP28 were analyzed. The study demonstrated that marine yeast diet administered once every seven days conferred better protection to P. monodon against WSSV infection, supported by the hematological and immune gene expression profiles analyzed. © 2012 Elsevier Inc.
Ullattil S.G.,University of CalicutKerala |
Periyat P.,University of CalicutKerala |
Periyat P.,Central University of Kerala
Journal of Materials Chemistry A | Year: 2016
A one pot gel combustion synthetic strategy has been developed for the first time towards the rapid formation of self-doped black anatase TiO2-x (BAT) using titanium butoxide, diethylene glycol (DEG) and water as the only precursors. This swiftly formed nanoplatform was occupied with a high concentration of surface defect sites, especially Ti3+ and oxygen vacancy sites in excess. The in (lattice) and out (surface) defect states were confirmed by Raman, XPS and TEM analysis. These defect-enriched features enabled 33% more photocatalytic activity for BAT than the commercially available photocatalyst Degussa-P25 under solar illumination. © The Royal Society of Chemistry 2016.
Inesi G.,California Pacific Medical Center Research Institute |
Pilankatta R.,Central University of Kerala |
Tadini-Buoninsegni F.,University of Florence
Biochemical Journal | Year: 2014
Copper ATPases, in analogy with other members of the P-ATPase superfamily, contain a catalytic headpiece including an aspartate residue reactingwithATP to form a phosphoenzyme intermediate, and transmembrane helices containing cation-binding sites [TMBS (transmembrane metal-binding sites)] for catalytic activation and cation translocation. Following phosphoenzyme formation by utilization of ATP, bound copper undergoes displacement from the TMBS to the lumenal membrane surface, with no H+ exchange. Although PII-type ATPases sustain active transport of alkali/alkali-earth ions (i.e. Na+, Ca2+) against electrochemical gradients across defined membranes, PIB-type ATPases transfer transition metal ions (i.e. Cu+) from delivery to acceptor proteins and, prominently in mammalian cells, undergo trafficking from/to various membrane compartments. A specific component of copper ATPases is the NMBD (N-terminal metalbinding domain), containing up to six copper-binding sites in mammalian (ATP7A and ATP7B) enzymes. Copper occupancy of NMBD sites and interaction with the ATPase headpiece are required for catalytic activation. Furthermore, in the presence of copper, the NMBD allows interaction with protein kinase D, yielding phosphorylation of serine residues, ATP7B trafficking and protection from proteasome degradation. A specific feature of ATP7A is glycosylation and stabilization on plasma membranes. Cisplatin, a platinum-containing anti-cancer drug, binds to copper sites ofATP7A andATP7B, and undergoes vectorial displacement in analogy with copper. © 2014 Biochemical Society.
Mandal D.,Hebrew University of Jerusalem |
Ramanan R.,Hebrew University of Jerusalem |
Usharani D.,Hebrew University of Jerusalem |
Usharani D.,Indian Central Food Technological Research Institute |
And 4 more authors.
Journal of the American Chemical Society | Year: 2015
This article addresses the intriguing hydrogen-abstraction (H-abstraction) and oxygen-transfer (O-transfer) reactivity of a series of nonheme [FeIV(O)(TMC)(Lax)]z+ complexes, with a tetramethyl cyclam ligand and a variable axial ligand (Lax), toward three substrates: 1,4-cyclohexadiene, 9,10-dihydroanthracene, and triphenyl phosphine. Experimentally, O-transfer-reactivity follows the relative electrophilicity of the complexes, whereas the corresponding H-abstraction-reactivity generally increases as the axial ligand becomes a better electron donor, hence exhibiting an antielectrophilic trend. Our theoretical results show that the antielectrophilic trend in H-abstraction is affected by tunneling contributions. Room-temperature tunneling increases with increase of the electron donation power of the axial-ligand, and this reverses the natural electrophilic trend, as revealed through calculations without tunneling, and leads to the observed antielectrophilic trend. By contrast, O-transfer-reactivity, not being subject to tunneling, retains an electrophilic-dependent reactivity trend, as revealed experimentally and computationally. Tunneling-corrected kinetic-isotope effect (KIE) calculations matched the experimental KIE values only if all of the H-abstraction reactions proceeded on the quintet state (S = 2) surface. As such, the present results corroborate the initially predicted two-state reactivity (TSR) scenario for these reactions. The increase of tunneling with the electron-releasing power of the axial ligand, and the reversal of the "natural" reactivity pattern, support the "tunneling control" hypothesis (Schreiner et al., ref 19). Should these predictions be corroborated, the entire field of C-H bond activation in bioinorganic chemistry would lay open to reinvestigation. © 2014 American Chemical Society.
R A.,Thomas College |
Mathew V.,Central University of Kerala
Plasmonics | Year: 2013
We study the properties of surface plasmon polaritons at an interface between a metal and a strongly nonlinear magnetic cladding, characterized by permeability μ = μ1 + μn1H2. It is observed that the dispersion of modes has a significant dependance on the incident power. The incident power can be adjusted to control the propagation length. In addition, the structure shows strong confinement of the modes at the interface. © 2012 Springer Science+Business Media, LLC.
Sadath A.C.,Central University of Kerala |
Acharya R.H.,National Institute of Technology Karnataka
Energy Economics | Year: 2015
This paper analyses the effects of the rising prices of energy products on the investment of a large panel of manufacturing firms in India during 1993-2013. The prime motivation behind this study is the absence of an empirical study into this research issue exclusively on Indian economy. The empirical results obtained by estimating an Error Correction Model (ECM) using Generalized Method of Moments (GMM) show that energy price rise has negative effect on the investment of firms in the manufacturing sector. The negative effect is transmitted to the firm's investment through both demand-side and supply-side factors. The transmission also depends upon factors such as the energy intensity of production. The results also show that the sales-growth-investment relationship becomes weak in the face of the rising prices of the energy which could be due to the cautious approach to investment adopted by the firms. Therefore, it calls for the attention of the policy makers to evolve a comprehensive energy-policy to ensure continuous supply of energy at affordable prices to the manufacturers. © 2015 Elsevier B.V.
R A.,Central University of Kerala |
Mathew V.,Central University of Kerala
Plasmonics | Year: 2015
We report the near field localized surface plasmon characteristics of triangular system of silver nanocylinders and shell nanocylinders interacting with incident plane wave, studied using finite element method. The trimer nanocylinder system possesses far greater structural tunability than either a single nanorod or a nanoshell, along with much larger local field intensity enhancements and far greater sensitivity. The effect of geometrical as well as material parameters on the longitudinal localized plasmon resonance of the trimer nanosystem was investigated. The results provide insight in to the possible tunability of the localized plasmon modes which could find application in designing of chemical and biological sensors, electron emitters, etc. © 2015 Springer Science+Business Media New York
D'Souza N.M.,Central University of Kerala |
Mathew V.,Central University of Kerala
Applied Optics | Year: 2015
The microwave optical properties of a photonic crystal-based tunable single and multichannel filter are theoretically investigated using the transfer matrix method, finite difference time domain method, and the plane wave expansion method. By applying an external voltage of 8 V/micron about a 35% frequency tuning is obtained. It is found that the number of transmission peaks is directly proportional to the number of periods (N). In addition to this, the dependence of layer thicknesses, angle of incidence and polarization are also analyzed, and it is noticed that the filtering frequency is invariant in angle and polarization. © 2015 Optical Society of America.
Chithra M.,Central University of Kerala |
Anumol C.N.,Central University of Kerala |
Sahu B.,Indian Institute of Technology Bombay |
Sahoo S.C.,Central University of Kerala
Journal of Magnetism and Magnetic Materials | Year: 2016
Cobalt ferrite nanoparticles were prepared by sol-gel technique and were annealed at 900°C in air for 2 h. Structural properties were studied by X-ray diffraction, Raman spectroscopy and Fourier transformed infrared spectroscopy. Scanning electron microscopy and transmission electron microscopy studies show presence of mostly two different sizes of grains in these samples. Magnetization value of 58.36 emu/g was observed at 300 K for the as prepared sample and an enhanced magnetization close to the bulk value of 80.59 emu/g was observed for the annealed sample. At 10 K a two stepped hysteresis loop showing exchange spring magnetic behavior was observed accompanied by very high values of coercivity and remanence. Two clear peaks were observed in the derivative of demagnetization curve in the as prepared sample where as two partially overlapped peaks were observed in the annealed sample. The observed magnetic properties can be understood on the basis of the grain size and their distribution leading to the different types of intergranular interactions in these nanoparticles. © 2015 Elsevier B.V.
Salini K.,Central University of Kerala |
Suseel Rahul K.,Central University of Kerala |
Mathew V.,Central University of Kerala
Applied Physics A: Materials Science and Processing | Year: 2014
The electronic and optical properties of a single exciton in a CdSe/CdS/CdSe/CdS quantum dot is studied by using effective mass approximation with parabolic confinement. The Coloumbic interaction between electron and hole is included by Hartree potential. A self-consistent technique is used to calculate the energy eigenvalue and wavefunction of exciton. Based on this approximation we investigate the effect of core size, shell thickness, well width on exciton binding energy, absorption spectra, and oscillator strength. The results provide the tuning possibility of electronic and optical properties of multilayer quantum dot with layer thickness. © 2014 Springer-Verlag Berlin Heidelberg.